UA92604C2 - Композиция стансопорфина с физиологической осмотической концентрацией и ее применение - Google Patents
Композиция стансопорфина с физиологической осмотической концентрацией и ее применениеInfo
- Publication number
- UA92604C2 UA92604C2 UAA200712058A UAA200712058A UA92604C2 UA 92604 C2 UA92604 C2 UA 92604C2 UA A200712058 A UAA200712058 A UA A200712058A UA A200712058 A UAA200712058 A UA A200712058A UA 92604 C2 UA92604 C2 UA 92604C2
- Authority
- UA
- Ukraine
- Prior art keywords
- stannsoporfin
- composition
- physiological osmolarity
- pharmaceutical compositions
- methods
- Prior art date
Links
- LLDZJTIZVZFNCM-UHFFFAOYSA-J 3-[18-(2-carboxyethyl)-8,13-diethyl-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;dichlorotin(2+) Chemical compound [H+].[H+].[Cl-].[Cl-].[Sn+4].[N-]1C(C=C2C(=C(C)C(=CC=3C(=C(C)C(=C4)N=3)CC)[N-]2)CCC([O-])=O)=C(CCC([O-])=O)C(C)=C1C=C1C(C)=C(CC)C4=N1 LLDZJTIZVZFNCM-UHFFFAOYSA-J 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229950001307 stannsoporfin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 229940126534 drug product Drugs 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение раскрывает фармацевтические композиции, которые содержат стансопорфин, а также способы лечения гипербилирубинемии с их помощью.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/096,359 US20060222668A1 (en) | 2005-04-01 | 2005-04-01 | Stannsoporfin compositions, drug products and methods of manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA92604C2 true UA92604C2 (ru) | 2010-11-25 |
Family
ID=37070775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200712058A UA92604C2 (ru) | 2005-04-01 | 2006-03-31 | Композиция стансопорфина с физиологической осмотической концентрацией и ее применение |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20060222668A1 (ru) |
| EP (1) | EP2301548A1 (ru) |
| JP (1) | JP2008534618A (ru) |
| CN (1) | CN101160053A (ru) |
| BR (1) | BRPI0609794A2 (ru) |
| EA (1) | EA013597B1 (ru) |
| IL (1) | IL186337A0 (ru) |
| MX (1) | MX2007012166A (ru) |
| NZ (1) | NZ562158A (ru) |
| UA (1) | UA92604C2 (ru) |
| ZA (1) | ZA200708892B (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7375216B2 (en) * | 2002-06-04 | 2008-05-20 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin compounds |
| US20060222668A1 (en) * | 2005-04-01 | 2006-10-05 | Wellspring Pharmaceutical Corporation | Stannsoporfin compositions, drug products and methods of manufacture |
| US8142781B2 (en) * | 2005-10-07 | 2012-03-27 | Armagen Technologies, Inc. | Fusion proteins for blood-brain barrier delivery |
| JP2010505854A (ja) * | 2006-10-04 | 2010-02-25 | インファケア ファーマスーティカル,コーポレイション | 低投与量のスタンソポルフィンを用いる幼児の高ビリルビン血症の治療 |
| ATE524187T1 (de) | 2006-10-04 | 2011-09-15 | Infacare Pharmaceutical Corp | Herstellung grosser mengen von hochreinem stannsoporfin |
| DK2691398T3 (en) | 2011-03-30 | 2017-01-16 | Infacare Pharmaceutical Corp | Methods for synthesizing metal mesoporphyrins |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4684637A (en) * | 1981-07-15 | 1987-08-04 | The Rockefeller University | Method of decreasing rate of heme metabolism |
| US4708964A (en) * | 1984-02-09 | 1987-11-24 | Chemex Pharmaceuticals | Lipoxygenase inhibitors |
| US4619923A (en) * | 1985-01-14 | 1986-10-28 | The Rockefeller University | Metal protoporphyrins in the control of tryptophan metabolism |
| US4657902A (en) * | 1985-03-25 | 1987-04-14 | The Rockefeller University | Therapeutic use of tin mesoporphyrin |
| US4692440A (en) * | 1985-03-25 | 1987-09-08 | The Rockefeller University | Therapeutic use of tin mesoporphyrin |
| US4692439A (en) * | 1986-06-20 | 1987-09-08 | The Rockefeller University | Therapeutic use of tin diiododeuteroporphyrin |
| US4668670A (en) * | 1986-06-20 | 1987-05-26 | The Rockefeller University | Tin diiododeuteroporphyrin and therapeutic use thereof |
| US4861876A (en) * | 1986-11-26 | 1989-08-29 | Wayne State University | Hematoporphyrin derivative and method of preparation and purification |
| US4782049A (en) * | 1986-12-08 | 1988-11-01 | The Rockefeller University | Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis |
| US4900871A (en) * | 1987-01-02 | 1990-02-13 | Sun Refining And Marketing Company | Hydrocarbon oxidations catalyzed by iron coordination complexes containing a halogenated ligand |
| US5990363A (en) * | 1987-01-02 | 1999-11-23 | Sun Company, Inc. | Method for oxidizing alkanes using novel porphyrins synthesized from dipyrromethanes and aldehydes |
| US5081115A (en) * | 1987-10-15 | 1992-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Method to prevent neonatal jaundice with metalloporphyrin compositions |
| US4831024A (en) * | 1987-10-15 | 1989-05-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method to prevent neonatal jaundice |
| DE3827940A1 (de) * | 1988-08-13 | 1990-03-01 | Schering Ag | 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| US4861676A (en) * | 1988-08-29 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Improved coextrudable adhesive and products therefrom |
| US5162313A (en) * | 1989-03-16 | 1992-11-10 | The Rockefeller University | Control of heme and iron concentrations in body tissues |
| US5223494A (en) * | 1989-09-25 | 1993-06-29 | The Rockefeller University | Orally administered porphyrins to control intestinal iron absorption |
| US5062775A (en) * | 1989-09-29 | 1991-11-05 | Rocky Mountain Research, Inc. | Roller pump in an extra corporeal support system |
| US5010073A (en) * | 1989-10-05 | 1991-04-23 | The Rockefeller University | Use of liposomes as carriers for metalloporphyrins |
| US5192757A (en) * | 1990-12-20 | 1993-03-09 | Glaxo Inc. | Cobalt porphyrins |
| US5371199B1 (en) * | 1992-08-14 | 1995-12-26 | Univ Pennsylvania | Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor |
| US5817830A (en) * | 1992-08-14 | 1998-10-06 | Trustees Of The University Of Pennsylvania | Pyrrolic compounds |
| US5493017A (en) * | 1992-08-14 | 1996-02-20 | The Trustees Of The University Of Pennsylvania | Ring-metalated porphyrins |
| CA2130853A1 (en) * | 1994-08-25 | 1996-02-26 | Svetlana Kudrevich | Process for the syntheses of monosulphonated phthalocyanines, naphthobenzoporphyrazines and porphyrins via a modified meerwein reaction |
| US6066333A (en) * | 1994-09-22 | 2000-05-23 | William Harvey Research Limited | Pharmaceutical control of inflammation |
| US5912341A (en) * | 1995-03-14 | 1999-06-15 | Hoffman/Barrett, L.L.C. | Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom |
| US5929064A (en) * | 1995-08-02 | 1999-07-27 | Warner-Lambert Company | Amino acid complexes of cobalt (III) mesoporphyrin IX and cobalt (III) protoporphyrin IX |
| US5883246A (en) * | 1996-03-07 | 1999-03-16 | Qlt Phototherapeutics, Inc. | Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds |
| US6004530A (en) * | 1996-06-04 | 1999-12-21 | Roche Diagnostics Gmbh | Use of metallo-porphyrin conjugates for the detection of biological substances |
| GB9616353D0 (en) * | 1996-08-03 | 1996-09-11 | Secr Defence | Metallo-porphyrins |
| US6124452A (en) * | 1997-12-19 | 2000-09-26 | University Of Nebraska-Lincoln | Octafluoro-meso-tetraarylporphyrins and methods for making these compounds |
| DE19706490C1 (de) * | 1997-02-19 | 1998-09-17 | Deutsches Krebsforsch | Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen |
| US5886173A (en) * | 1997-07-30 | 1999-03-23 | Pharmacyclics, Inc. | Metallation of macrocycles with 2,4-dicarbonyl-metal complexes |
| US6194566B1 (en) * | 1997-12-02 | 2001-02-27 | Schering Aktiengesellschaft | Process for the production of metalloporphyrin-metal complex conjugates |
| JP3673888B2 (ja) * | 1998-03-09 | 2005-07-20 | 独立行政法人科学技術振興機構 | ポルフィリン類金属錯体の製造方法 |
| DE19831217A1 (de) * | 1998-07-03 | 2000-01-05 | Schering Ag | Neue Porphyrinderivate, diese enthaltende pharmazeutische Mittel und ihre Verwendung in der photodynamischen Therapie und MRI-Diagnostik |
| US5973141A (en) * | 1998-11-27 | 1999-10-26 | Miravant Pharmaceuticals, Inc. | Method for the demethoxycarbonylation of porphyrinic compounds such as pheophorbides |
| US6462192B2 (en) * | 2001-01-23 | 2002-10-08 | Miravant Pharmaceuticals, Inc. | Processes for large scale production of tetrapyrroles |
| WO2002096417A1 (en) * | 2001-05-31 | 2002-12-05 | Miravant Pharmaceuticals, Inc. | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and mri diagnosis |
| US7375216B2 (en) * | 2002-06-04 | 2008-05-20 | Infacare Pharmaceutical Corporation | Preparation of metal mesoporphyrin compounds |
| WO2003101999A2 (en) * | 2002-06-04 | 2003-12-11 | Wellspring Pharmaceutical Corporation | Preparation of metal mesoporphyrin halide compounds |
| US20040097481A1 (en) * | 2002-11-20 | 2004-05-20 | Benjamin Levinson | Water-soluble mesoporphyrin compounds and methods of preparation |
| DE602004019761D1 (de) * | 2003-01-08 | 2009-04-16 | Novartis Vaccines & Diagnostic | Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante |
| US20060222668A1 (en) * | 2005-04-01 | 2006-10-05 | Wellspring Pharmaceutical Corporation | Stannsoporfin compositions, drug products and methods of manufacture |
| ATE524187T1 (de) * | 2006-10-04 | 2011-09-15 | Infacare Pharmaceutical Corp | Herstellung grosser mengen von hochreinem stannsoporfin |
| JP2010505854A (ja) * | 2006-10-04 | 2010-02-25 | インファケア ファーマスーティカル,コーポレイション | 低投与量のスタンソポルフィンを用いる幼児の高ビリルビン血症の治療 |
-
2005
- 2005-04-01 US US11/096,359 patent/US20060222668A1/en not_active Abandoned
- 2005-09-30 US US11/239,769 patent/US20060222669A1/en not_active Abandoned
-
2006
- 2006-03-31 NZ NZ562158A patent/NZ562158A/en not_active IP Right Cessation
- 2006-03-31 JP JP2008504470A patent/JP2008534618A/ja not_active Withdrawn
- 2006-03-31 MX MX2007012166A patent/MX2007012166A/es unknown
- 2006-03-31 EP EP10014149A patent/EP2301548A1/en not_active Withdrawn
- 2006-03-31 BR BRPI0609794-4A patent/BRPI0609794A2/pt not_active IP Right Cessation
- 2006-03-31 UA UAA200712058A patent/UA92604C2/ru unknown
- 2006-03-31 EA EA200702136A patent/EA013597B1/ru not_active IP Right Cessation
- 2006-03-31 CN CNA2006800127792A patent/CN101160053A/zh active Pending
-
2007
- 2007-10-07 IL IL186337A patent/IL186337A0/en unknown
- 2007-10-17 ZA ZA200708892A patent/ZA200708892B/en unknown
-
2008
- 2008-04-22 US US12/107,658 patent/US20080261939A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0609794A2 (pt) | 2010-04-27 |
| US20060222669A1 (en) | 2006-10-05 |
| EA200702136A1 (ru) | 2008-04-28 |
| CN101160053A (zh) | 2008-04-09 |
| US20080261939A1 (en) | 2008-10-23 |
| NZ562158A (en) | 2011-04-29 |
| ZA200708892B (en) | 2008-06-25 |
| MX2007012166A (es) | 2007-12-10 |
| US20060222668A1 (en) | 2006-10-05 |
| EP2301548A1 (en) | 2011-03-30 |
| IL186337A0 (en) | 2008-01-20 |
| EA013597B1 (ru) | 2010-06-30 |
| JP2008534618A (ja) | 2008-08-28 |
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