TR200003157T2 - Abacavir, lamivudin ve zidovudin içeren homojen farmasötik bileşimler - Google Patents

Abacavir, lamivudin ve zidovudin içeren homojen farmasötik bileşimler

Info

Publication number: TR200003157T2
Authority: TR; Turkey
Prior art keywords: lamivudine; zidovudine; pharmaceutical compositions; compositions containing; abacavir
Prior art date: 1998-04-29

Application number

TR2000/03157T

Other languages

English (en)

Turkish (tr)

Inventor

Currie Robin

Jain Sunil

Wayne Wood Allen

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-04-29

Filing date

1999-04-26

Publication date

2001-01-22

1999-04-26 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2001-01-22 Publication of TR200003157T2 publication Critical patent/TR200003157T2/xx

Links

LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 title abstract 2
229960004748 abacavir Drugs 0.000 title abstract 2
MCGSCOLBFJQGHM-SCZZXKLOSA-N abacavir Chemical compound C=12N=CN([C@H]3C=C[C@@H](CO)C3)C2=NC(N)=NC=1NC1CC1 MCGSCOLBFJQGHM-SCZZXKLOSA-N 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
241000725303 Human immunodeficiency virus Species 0.000 abstract 3
230000000840 anti-viral effect Effects 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Biophysics (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

TR2000/03157T 1998-04-29 1999-04-26 Abacavir, lamivudin ve zidovudin içeren homojen farmasötik bileşimler TR200003157T2 (tr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9809213.3A GB9809213D0 (en)	1998-04-29	1998-04-29	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
TR200003157T2 true TR200003157T2 (tr)	2001-01-22

Family

ID=10831228

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TR2000/03157T TR200003157T2 (tr)	1998-04-29	1999-04-26	Abacavir, lamivudin ve zidovudin içeren homojen farmasötik bileşimler

Country Status (23)

Country	Link
EP (1)	EP1083932A1 (is)
JP (1)	JP2002512979A (is)
KR (1)	KR20010043128A (is)
CN (1)	CN1411380A (is)
AP (1)	AP2000001971A0 (is)
AU (1)	AU4135599A (is)
BR (1)	BR9910071A (is)
CA (1)	CA2330391A1 (is)
EA (1)	EA200000997A1 (is)
EE (1)	EE200000646A (is)
GB (1)	GB9809213D0 (is)
HR (1)	HRP20000732A2 (is)
HU (1)	HUP0101622A3 (is)
ID (1)	ID26955A (is)
IL (1)	IL139181A0 (is)
IS (1)	IS5675A (is)
NO (1)	NO20005418L (is)
NZ (1)	NZ507745A (is)
PL (1)	PL343710A1 (is)
SK (1)	SK16212000A3 (is)
TR (1)	TR200003157T2 (is)
WO (1)	WO1999055372A1 (is)
ZA (1)	ZA200005922B (is)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6875773B1 (en)	1998-05-29	2005-04-05	Ben M. Dunn	Combination therapy for treatment of FIV infection
CA2374198A1 (en) *	1998-05-29	1999-12-02	Maki Arai	Combination therapy for treatment of fiv infection
GB9820417D0 (en) *	1998-09-18	1998-11-11	Glaxo Group Ltd	Antiviral combinations
US7074417B2 (en) *	2000-10-13	2006-07-11	Advancis Pharmaceutical Corporation	Multiple-delayed release anti-viral product, use and formulation thereof
DE60219965T2 (de) *	2002-04-23	2008-01-17	Lupin Ltd., Mumbai	Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine
TW200403061A (en) *	2002-06-04	2004-03-01	Glaxo Group Ltd	Pharmaceutical compositions
CN100335125C (zh) *	2003-06-03	2007-09-05	上海现代药物制剂工程研究中心	杀毒抗菌用长效干扰素喷鼻粉剂
WO2006114709A1 (en) *	2005-04-25	2006-11-02	Aurobindo Pharma Limited	Pharmaceutical compositions of antiretrovirals
WO2007013047A2 (en) *	2005-07-29	2007-02-01	Ranbaxy Laboratories Limited	Water-dispersible anti-retroviral pharmaceutical compositions
ES2279707B1 (es) *	2005-11-10	2008-06-01	Combino Pharm, S.L.	Formulaciones orales que comprenden 3'-azidonucleosidos.
US20110053884A1 (en) *	2007-10-02	2011-03-03	Schinazi Raymond F	Potent combinations of zidovudine and drugs that select for the k65r mutation in the hiv polymerase
GB2470494B (en) *	2008-01-17	2012-08-08	Univ Holy Ghost Duquesne	Antiretroviral drug formulations for treatment of children exposed to HIV/AIDS
PH12012501537A1 (en) *	2010-01-27	2018-02-07	Viiv Healthcare Co	Antiviral therapy
CN114010776A (zh)	2010-06-09	2022-02-08	疫苗技术股份有限公司	用于增强抗逆转录病毒治疗的hiv感染者的治疗性免疫
EP2822560A1 (en)	2012-03-05	2015-01-14	Cipla Limited	Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine
CN104884063A (zh)	2012-10-23	2015-09-02	西普拉有限公司	抗逆转录病毒药物组合物
EP3007695B1 (en)	2013-06-13	2024-02-07	Akebia Therapeutics, Inc.	Compositions and methods for treating anemia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY115461A (en) *	1995-03-30	2003-06-30	Wellcome Found	Synergistic combinations of zidovudine, 1592u89 and 3tc
GB9622681D0 (en) *	1996-10-31	1997-01-08	Glaxo Group Ltd	Pharmaceutical compositions

1998
- 1998-04-29 GB GBGB9809213.3A patent/GB9809213D0/en not_active Ceased
1999
- 1999-04-26 AU AU41355/99A patent/AU4135599A/en not_active Abandoned
- 1999-04-26 JP JP2000545569A patent/JP2002512979A/ja active Pending
- 1999-04-26 SK SK1621-2000A patent/SK16212000A3/sk unknown
- 1999-04-26 KR KR1020007012021A patent/KR20010043128A/ko not_active Withdrawn
- 1999-04-26 WO PCT/EP1999/002794 patent/WO1999055372A1/en not_active Ceased
- 1999-04-26 HR HR20000732A patent/HRP20000732A2/hr not_active Application Discontinuation
- 1999-04-26 CA CA002330391A patent/CA2330391A1/en not_active Abandoned
- 1999-04-26 ID IDW20002479A patent/ID26955A/id unknown
- 1999-04-26 NZ NZ507745A patent/NZ507745A/en unknown
- 1999-04-26 EP EP99924822A patent/EP1083932A1/en not_active Withdrawn
- 1999-04-26 IL IL13918199A patent/IL139181A0/xx unknown
- 1999-04-26 EE EEP200000646A patent/EE200000646A/xx unknown
- 1999-04-26 AP APAP/P/2000/001971A patent/AP2000001971A0/en unknown
- 1999-04-26 CN CN99807983A patent/CN1411380A/zh active Pending
- 1999-04-26 BR BR9910071-1A patent/BR9910071A/pt not_active IP Right Cessation
- 1999-04-26 TR TR2000/03157T patent/TR200003157T2/xx unknown
- 1999-04-26 HU HU0101622A patent/HUP0101622A3/hu unknown
- 1999-04-26 PL PL99343710A patent/PL343710A1/xx unknown
- 1999-04-26 EA EA200000997A patent/EA200000997A1/ru unknown
2000
- 2000-10-20 IS IS5675A patent/IS5675A/is unknown
- 2000-10-23 ZA ZA200005922A patent/ZA200005922B/xx unknown
- 2000-10-27 NO NO20005418A patent/NO20005418L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20010043128A (ko)	2001-05-25
NO20005418L (no)	2000-11-29
PL343710A1 (en)	2001-08-27
CN1411380A (zh)	2003-04-16
NO20005418D0 (no)	2000-10-27
ZA200005922B (en)	2001-10-23
EP1083932A1 (en)	2001-03-21
AU4135599A (en)	1999-11-16
HUP0101622A2 (hu)	2002-03-28
GB9809213D0 (en)	1998-07-01
IS5675A (is)	2000-10-20
EA200000997A1 (ru)	2001-06-25
BR9910071A (pt)	2000-12-26
WO1999055372A1 (en)	1999-11-04
EE200000646A (et)	2002-04-15
ID26955A (id)	2001-02-22
NZ507745A (en)	2004-07-30
JP2002512979A (ja)	2002-05-08
IL139181A0 (en)	2001-11-25
HRP20000732A2 (en)	2001-02-28
CA2330391A1 (en)	1999-11-04
HUP0101622A3 (en)	2003-09-29
SK16212000A3 (sk)	2001-07-10
AP2000001971A0 (en)	2000-12-31

Publication	Publication Date	Title
TR200003157T2 (tr)	2001-01-22	Abacavir, lamivudin ve zidovudin içeren homojen farmasötik bileşimler
DE69632256D1 (de)	2004-05-27	Antivirale proteine, dafür kodierende dna, und deren verwendung
FI20001231A7 (fi)	2000-05-23	2-Deoksi-2,3-didehydro-N-asetyylineuramiinihapon johdannaisia ja niiden analogeja ja niiden käyttö antiviraalisina aineina
DK1126828T3 (da)	2009-06-15	Oral indgivelse af adenosin-analoger
MXPA02006679A (es)	2005-12-19	Composicion farmaceutica.
NZ333707A (en)	2000-09-29	Antiviral compositions comprising Aeginetiae herba derived from plant extracts and at least one other Chinese herbal medicine
BR9811121A (pt)	2000-07-18	Produto, composição farmacêutica, e uso de um produto
TR200001892T2 (tr)	2000-11-21	Monomer cinsi ensülin analogları ve bunların kullanımı.
UA29429C2 (uk)	2000-11-15	Фармацевтична композиція для лікування вірусних інфекцій, спосіб отримання композиції, спосіб лікування або профілактики віл-інфекції у людини
BR0210350A (pt)	2004-07-20	Nucleosìdeos 4'-substituìdos
RU94013464A (ru)	1995-12-10	Нуклеозидные аналоги 1,3-оксатиолана, способ получения, фармацевтическая композиция, способ лечения вирусной инфекции
MXPA02007478A (es)	2004-08-23	Vacuna contra el virus de inmunodeficiencia humana.
ES2177695T3 (es)	2002-12-16	Uso de derivados funcionales de la molecual de adhesion intercelular icam-1 en terapia antiviral.
DK92788A (da)	1988-02-23	Anvendelse af 3'-deoxy-3'-flourguanosider til fremstilling af laegemidler mod retrovira
ES2151600T3 (es)	2001-01-01	Derivados de n-(3-amino-2-hidroxibutil)sulfonamida utilizados como inhibidores de proteasa de vih.
ES2179110T3 (es)	2003-01-16	Succinato 4-(2-amino-6-(ciclopropilamino)-9h-purin-9-il)-2-ciclopenteno-1-metanol como agente antiviral.
EA199900345A1 (ru)	2000-02-28	Фармацевтические композиции, содержащие ламивудин и зидовудин
DK615788D0 (da)	1988-11-04	Nucleosidforbindelser til anvendelse mod virale infektioner
PA8449301A1 (es)	2000-05-24	Composiciones farmaceuticas
ES2064748T3 (es)	1995-02-01	Composiciones antiviricas conteniendo derivados del sulfoquinovosil glicerol y analogos del mismo y su uso.
AP2000001930A0 (en)	2000-09-30	AZT derivatives exhihibiting spermicidal and anti-viral activity.
MX9700044A (es)	1997-04-30	Combinacion triple anti-virus de inmunodeficiencia humana.
ATE232108T1 (de)	2003-02-15	Interleukin - 8 als antivirale- und antitumorwirkstoffe
AU7512287A (en)	1987-12-22	Expression of human t-cell lymphotropic virus (htlv-iii)reve rse transcriptase and uses thereof
BR0207566A (pt)	2004-09-14	Processo para preparação de (e)-5-(2-bromovinil)-2'-desoxiuridina