EA200000997A1 - Гомогенные фармацевтические композиции, содержащие абакавир, ламивудин и зидовудин - Google Patents
Гомогенные фармацевтические композиции, содержащие абакавир, ламивудин и зидовудинInfo
- Publication number
- EA200000997A1 EA200000997A1 EA200000997A EA200000997A EA200000997A1 EA 200000997 A1 EA200000997 A1 EA 200000997A1 EA 200000997 A EA200000997 A EA 200000997A EA 200000997 A EA200000997 A EA 200000997A EA 200000997 A1 EA200000997 A1 EA 200000997A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- abakavir
- lamivudin
- zidovudin
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 abstract 1
- 229960004748 abacavir Drugs 0.000 abstract 1
- MCGSCOLBFJQGHM-SCZZXKLOSA-N abacavir Chemical compound C=12N=CN([C@H]3C=C[C@@H](CO)C3)C2=NC(N)=NC=1NC1CC1 MCGSCOLBFJQGHM-SCZZXKLOSA-N 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809213.3A GB9809213D0 (en) | 1998-04-29 | 1998-04-29 | Pharmaceutical compositions |
| PCT/EP1999/002794 WO1999055372A1 (en) | 1998-04-29 | 1999-04-26 | Homogeneous pharmaceutical compositions comprising abacavir, lamivudine and zidovudine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200000997A1 true EA200000997A1 (ru) | 2001-06-25 |
Family
ID=10831228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200000997A EA200000997A1 (ru) | 1998-04-29 | 1999-04-26 | Гомогенные фармацевтические композиции, содержащие абакавир, ламивудин и зидовудин |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1083932A1 (is) |
| JP (1) | JP2002512979A (is) |
| KR (1) | KR20010043128A (is) |
| CN (1) | CN1411380A (is) |
| AP (1) | AP2000001971A0 (is) |
| AU (1) | AU4135599A (is) |
| BR (1) | BR9910071A (is) |
| CA (1) | CA2330391A1 (is) |
| EA (1) | EA200000997A1 (is) |
| EE (1) | EE200000646A (is) |
| GB (1) | GB9809213D0 (is) |
| HR (1) | HRP20000732A2 (is) |
| HU (1) | HUP0101622A3 (is) |
| ID (1) | ID26955A (is) |
| IL (1) | IL139181A0 (is) |
| IS (1) | IS5675A (is) |
| NO (1) | NO20005418L (is) |
| NZ (1) | NZ507745A (is) |
| PL (1) | PL343710A1 (is) |
| SK (1) | SK16212000A3 (is) |
| TR (1) | TR200003157T2 (is) |
| WO (1) | WO1999055372A1 (is) |
| ZA (1) | ZA200005922B (is) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875773B1 (en) | 1998-05-29 | 2005-04-05 | Ben M. Dunn | Combination therapy for treatment of FIV infection |
| EP1146882A2 (en) * | 1998-05-29 | 2001-10-24 | The University Of Florida | Combination of zidovudine (azt) with nucleoside analogs for treatment of feline immunodeficiency virus |
| GB9820417D0 (en) * | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
| US7074417B2 (en) * | 2000-10-13 | 2006-07-11 | Advancis Pharmaceutical Corporation | Multiple-delayed release anti-viral product, use and formulation thereof |
| BR0215707A (pt) * | 2002-04-23 | 2005-05-03 | Lupin Ltd | Composição farmacêutica para a liberação controlada de ingredientes ativos e processo para a preparação de uma composição farmacêutica |
| TW200403061A (en) * | 2002-06-04 | 2004-03-01 | Glaxo Group Ltd | Pharmaceutical compositions |
| CN100335125C (zh) * | 2003-06-03 | 2007-09-05 | 上海现代药物制剂工程研究中心 | 杀毒抗菌用长效干扰素喷鼻粉剂 |
| US20110104267A1 (en) * | 2005-04-25 | 2011-05-05 | Aurobindo Pharma Limited | Pharmaceutical compositions of antiretrovirals |
| WO2007013047A2 (en) * | 2005-07-29 | 2007-02-01 | Ranbaxy Laboratories Limited | Water-dispersible anti-retroviral pharmaceutical compositions |
| ES2279707B1 (es) * | 2005-11-10 | 2008-06-01 | Combino Pharm, S.L. | Formulaciones orales que comprenden 3'-azidonucleosidos. |
| CN101878032A (zh) * | 2007-10-02 | 2010-11-03 | 埃默里大学 | 齐多夫定和针对hiv聚合酶中k65r突变选择的药剂的强力组合 |
| GB2470494B (en) * | 2008-01-17 | 2012-08-08 | Univ Holy Ghost Duquesne | Antiretroviral drug formulations for treatment of children exposed to HIV/AIDS |
| SMT201800290T1 (it) * | 2010-01-27 | 2018-07-17 | Viiv Healthcare Co | Terapia antivirale |
| US20130115237A1 (en) | 2010-06-09 | 2013-05-09 | Vaccine Technologies, Incorporated | Therapeutic immunization in hiv infected subjects to augment antiretroviral treatment |
| IN2014MN01907A (is) | 2012-03-05 | 2015-07-10 | Cipla Ltd | |
| NZ706223A (en) | 2012-10-23 | 2018-11-30 | Cipla Ltd | Pharmaceutical antiretroviral composition |
| SG11201509998WA (en) | 2013-06-13 | 2016-01-28 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY115461A (en) * | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
| GB9622681D0 (en) * | 1996-10-31 | 1997-01-08 | Glaxo Group Ltd | Pharmaceutical compositions |
-
1998
- 1998-04-29 GB GBGB9809213.3A patent/GB9809213D0/en not_active Ceased
-
1999
- 1999-04-26 HR HR20000732A patent/HRP20000732A2/hr not_active Application Discontinuation
- 1999-04-26 EE EEP200000646A patent/EE200000646A/xx unknown
- 1999-04-26 AU AU41355/99A patent/AU4135599A/en not_active Abandoned
- 1999-04-26 CA CA002330391A patent/CA2330391A1/en not_active Abandoned
- 1999-04-26 TR TR2000/03157T patent/TR200003157T2/xx unknown
- 1999-04-26 IL IL13918199A patent/IL139181A0/xx unknown
- 1999-04-26 NZ NZ507745A patent/NZ507745A/en unknown
- 1999-04-26 EP EP99924822A patent/EP1083932A1/en not_active Withdrawn
- 1999-04-26 EA EA200000997A patent/EA200000997A1/ru unknown
- 1999-04-26 PL PL99343710A patent/PL343710A1/xx unknown
- 1999-04-26 ID IDW20002479A patent/ID26955A/id unknown
- 1999-04-26 JP JP2000545569A patent/JP2002512979A/ja active Pending
- 1999-04-26 WO PCT/EP1999/002794 patent/WO1999055372A1/en not_active Ceased
- 1999-04-26 KR KR1020007012021A patent/KR20010043128A/ko not_active Withdrawn
- 1999-04-26 HU HU0101622A patent/HUP0101622A3/hu unknown
- 1999-04-26 CN CN99807983A patent/CN1411380A/zh active Pending
- 1999-04-26 AP APAP/P/2000/001971A patent/AP2000001971A0/en unknown
- 1999-04-26 BR BR9910071-1A patent/BR9910071A/pt not_active IP Right Cessation
- 1999-04-26 SK SK1621-2000A patent/SK16212000A3/sk unknown
-
2000
- 2000-10-20 IS IS5675A patent/IS5675A/is unknown
- 2000-10-23 ZA ZA200005922A patent/ZA200005922B/xx unknown
- 2000-10-27 NO NO20005418A patent/NO20005418L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002512979A (ja) | 2002-05-08 |
| CN1411380A (zh) | 2003-04-16 |
| HUP0101622A3 (en) | 2003-09-29 |
| SK16212000A3 (sk) | 2001-07-10 |
| HRP20000732A2 (en) | 2001-02-28 |
| NO20005418D0 (no) | 2000-10-27 |
| AP2000001971A0 (en) | 2000-12-31 |
| ID26955A (id) | 2001-02-22 |
| HUP0101622A2 (hu) | 2002-03-28 |
| IS5675A (is) | 2000-10-20 |
| NZ507745A (en) | 2004-07-30 |
| IL139181A0 (en) | 2001-11-25 |
| AU4135599A (en) | 1999-11-16 |
| TR200003157T2 (tr) | 2001-01-22 |
| GB9809213D0 (en) | 1998-07-01 |
| EE200000646A (et) | 2002-04-15 |
| NO20005418L (no) | 2000-11-29 |
| PL343710A1 (en) | 2001-08-27 |
| ZA200005922B (en) | 2001-10-23 |
| CA2330391A1 (en) | 1999-11-04 |
| KR20010043128A (ko) | 2001-05-25 |
| BR9910071A (pt) | 2000-12-26 |
| EP1083932A1 (en) | 2001-03-21 |
| WO1999055372A1 (en) | 1999-11-04 |
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