TR200003157T2 - Homogeneous pharmaceutical compositions containing abacavir, lamivudine and zidovudine - Google Patents
Homogeneous pharmaceutical compositions containing abacavir, lamivudine and zidovudineInfo
- Publication number
- TR200003157T2 TR200003157T2 TR2000/03157T TR200003157T TR200003157T2 TR 200003157 T2 TR200003157 T2 TR 200003157T2 TR 2000/03157 T TR2000/03157 T TR 2000/03157T TR 200003157 T TR200003157 T TR 200003157T TR 200003157 T2 TR200003157 T2 TR 200003157T2
- Authority
- TR
- Turkey
- Prior art keywords
- lamivudine
- zidovudine
- pharmaceutical compositions
- compositions containing
- abacavir
- Prior art date
Links
- LHCOVOKZWQYODM-CPEOKENHSA-N 4-amino-1-[(2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one;1-[(2r,4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1N=C(N)C=CN1[C@H]1O[C@@H](CO)SC1.O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 LHCOVOKZWQYODM-CPEOKENHSA-N 0.000 title abstract 2
- 229960004748 abacavir Drugs 0.000 title abstract 2
- MCGSCOLBFJQGHM-SCZZXKLOSA-N abacavir Chemical compound C=12N=CN([C@H]3C=C[C@@H](CO)C3)C2=NC(N)=NC=1NC1CC1 MCGSCOLBFJQGHM-SCZZXKLOSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 3
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Abacavir, lamivudin ve zidovudinin antiviral etki saglayan bir miktarda bir homojen kombinasyonunu içeren bir farmasötik bilesim, bu tip bir bilesimi hazirlamak için bir islem, ve bir insan bagisiklik eksikligi virüsü (HIV) enfeksiyonlu hastaya bu tip bir bilesimin uygulanmasini içeren HIV virüsü inhibe edici bir yöntem tarif edilmektedir.An HIV virus inhibitory method comprising a pharmaceutical composition comprising a homogeneous combination of abacavir, lamivudine and zidovudine in an amount that provides antiviral effect, a human immunodeficiency virus (HIV) infected patient. is described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809213.3A GB9809213D0 (en) | 1998-04-29 | 1998-04-29 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200003157T2 true TR200003157T2 (en) | 2001-01-22 |
Family
ID=10831228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/03157T TR200003157T2 (en) | 1998-04-29 | 1999-04-26 | Homogeneous pharmaceutical compositions containing abacavir, lamivudine and zidovudine |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1083932A1 (en) |
| JP (1) | JP2002512979A (en) |
| KR (1) | KR20010043128A (en) |
| CN (1) | CN1411380A (en) |
| AP (1) | AP2000001971A0 (en) |
| AU (1) | AU4135599A (en) |
| BR (1) | BR9910071A (en) |
| CA (1) | CA2330391A1 (en) |
| EA (1) | EA200000997A1 (en) |
| EE (1) | EE200000646A (en) |
| GB (1) | GB9809213D0 (en) |
| HR (1) | HRP20000732A2 (en) |
| HU (1) | HUP0101622A3 (en) |
| ID (1) | ID26955A (en) |
| IL (1) | IL139181A0 (en) |
| IS (1) | IS5675A (en) |
| NO (1) | NO20005418L (en) |
| NZ (1) | NZ507745A (en) |
| PL (1) | PL343710A1 (en) |
| SK (1) | SK16212000A3 (en) |
| TR (1) | TR200003157T2 (en) |
| WO (1) | WO1999055372A1 (en) |
| ZA (1) | ZA200005922B (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875773B1 (en) | 1998-05-29 | 2005-04-05 | Ben M. Dunn | Combination therapy for treatment of FIV infection |
| CA2374198A1 (en) * | 1998-05-29 | 1999-12-02 | Maki Arai | Combination therapy for treatment of fiv infection |
| GB9820417D0 (en) * | 1998-09-18 | 1998-11-11 | Glaxo Group Ltd | Antiviral combinations |
| US7074417B2 (en) * | 2000-10-13 | 2006-07-11 | Advancis Pharmaceutical Corporation | Multiple-delayed release anti-viral product, use and formulation thereof |
| DE60219965T2 (en) * | 2002-04-23 | 2008-01-17 | Lupin Ltd., Mumbai | LONG-LIQUID COMPOSITIONS CONTAINING ZIDOVUDINE AND / OR LAMIVUDINE |
| TW200403061A (en) * | 2002-06-04 | 2004-03-01 | Glaxo Group Ltd | Pharmaceutical compositions |
| CN100335125C (en) * | 2003-06-03 | 2007-09-05 | 上海现代药物制剂工程研究中心 | Interferon nasal spray powder with long service for detoxication and anti-bacteria |
| WO2006114709A1 (en) * | 2005-04-25 | 2006-11-02 | Aurobindo Pharma Limited | Pharmaceutical compositions of antiretrovirals |
| WO2007013047A2 (en) * | 2005-07-29 | 2007-02-01 | Ranbaxy Laboratories Limited | Water-dispersible anti-retroviral pharmaceutical compositions |
| ES2279707B1 (en) * | 2005-11-10 | 2008-06-01 | Combino Pharm, S.L. | ORAL FORMULATIONS THAT INCLUDE 3'-AZIDONUCLEOSIDS. |
| US20110053884A1 (en) * | 2007-10-02 | 2011-03-03 | Schinazi Raymond F | Potent combinations of zidovudine and drugs that select for the k65r mutation in the hiv polymerase |
| GB2470494B (en) * | 2008-01-17 | 2012-08-08 | Univ Holy Ghost Duquesne | Antiretroviral drug formulations for treatment of children exposed to HIV/AIDS |
| PH12012501537A1 (en) * | 2010-01-27 | 2018-02-07 | Viiv Healthcare Co | Antiviral therapy |
| CN114010776A (en) | 2010-06-09 | 2022-02-08 | 疫苗技术股份有限公司 | Therapeutic immunization of HIV-infected persons for enhancing antiretroviral therapy |
| EP2822560A1 (en) | 2012-03-05 | 2015-01-14 | Cipla Limited | Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine |
| CN104884063A (en) | 2012-10-23 | 2015-09-02 | 西普拉有限公司 | Pharmaceutical antiretroviral composition |
| EP3007695B1 (en) | 2013-06-13 | 2024-02-07 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY115461A (en) * | 1995-03-30 | 2003-06-30 | Wellcome Found | Synergistic combinations of zidovudine, 1592u89 and 3tc |
| GB9622681D0 (en) * | 1996-10-31 | 1997-01-08 | Glaxo Group Ltd | Pharmaceutical compositions |
-
1998
- 1998-04-29 GB GBGB9809213.3A patent/GB9809213D0/en not_active Ceased
-
1999
- 1999-04-26 AU AU41355/99A patent/AU4135599A/en not_active Abandoned
- 1999-04-26 JP JP2000545569A patent/JP2002512979A/en active Pending
- 1999-04-26 SK SK1621-2000A patent/SK16212000A3/en unknown
- 1999-04-26 KR KR1020007012021A patent/KR20010043128A/en not_active Withdrawn
- 1999-04-26 WO PCT/EP1999/002794 patent/WO1999055372A1/en not_active Ceased
- 1999-04-26 HR HR20000732A patent/HRP20000732A2/en not_active Application Discontinuation
- 1999-04-26 CA CA002330391A patent/CA2330391A1/en not_active Abandoned
- 1999-04-26 ID IDW20002479A patent/ID26955A/en unknown
- 1999-04-26 NZ NZ507745A patent/NZ507745A/en unknown
- 1999-04-26 EP EP99924822A patent/EP1083932A1/en not_active Withdrawn
- 1999-04-26 IL IL13918199A patent/IL139181A0/en unknown
- 1999-04-26 EE EEP200000646A patent/EE200000646A/en unknown
- 1999-04-26 AP APAP/P/2000/001971A patent/AP2000001971A0/en unknown
- 1999-04-26 CN CN99807983A patent/CN1411380A/en active Pending
- 1999-04-26 BR BR9910071-1A patent/BR9910071A/en not_active IP Right Cessation
- 1999-04-26 TR TR2000/03157T patent/TR200003157T2/en unknown
- 1999-04-26 HU HU0101622A patent/HUP0101622A3/en unknown
- 1999-04-26 PL PL99343710A patent/PL343710A1/en unknown
- 1999-04-26 EA EA200000997A patent/EA200000997A1/en unknown
-
2000
- 2000-10-20 IS IS5675A patent/IS5675A/en unknown
- 2000-10-23 ZA ZA200005922A patent/ZA200005922B/en unknown
- 2000-10-27 NO NO20005418A patent/NO20005418L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010043128A (en) | 2001-05-25 |
| NO20005418L (en) | 2000-11-29 |
| PL343710A1 (en) | 2001-08-27 |
| CN1411380A (en) | 2003-04-16 |
| NO20005418D0 (en) | 2000-10-27 |
| ZA200005922B (en) | 2001-10-23 |
| EP1083932A1 (en) | 2001-03-21 |
| AU4135599A (en) | 1999-11-16 |
| HUP0101622A2 (en) | 2002-03-28 |
| GB9809213D0 (en) | 1998-07-01 |
| IS5675A (en) | 2000-10-20 |
| EA200000997A1 (en) | 2001-06-25 |
| BR9910071A (en) | 2000-12-26 |
| WO1999055372A1 (en) | 1999-11-04 |
| EE200000646A (en) | 2002-04-15 |
| ID26955A (en) | 2001-02-22 |
| NZ507745A (en) | 2004-07-30 |
| JP2002512979A (en) | 2002-05-08 |
| IL139181A0 (en) | 2001-11-25 |
| HRP20000732A2 (en) | 2001-02-28 |
| CA2330391A1 (en) | 1999-11-04 |
| HUP0101622A3 (en) | 2003-09-29 |
| SK16212000A3 (en) | 2001-07-10 |
| AP2000001971A0 (en) | 2000-12-31 |
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