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TNSN98158A1 - Associations pharmaceutiques d'amlodipine et d'une statine, et procede pour leur preparation - Google Patents

Associations pharmaceutiques d'amlodipine et d'une statine, et procede pour leur preparation

Info

Publication number
TNSN98158A1
TNSN98158A1 TNTNSN98158A TNSN98158A TNSN98158A1 TN SN98158 A1 TNSN98158 A1 TN SN98158A1 TN TNSN98158 A TNTNSN98158 A TN TNSN98158A TN SN98158 A TNSN98158 A TN SN98158A TN SN98158 A1 TNSN98158 A1 TN SN98158A1
Authority
TN
Tunisia
Prior art keywords
amlodipine
preparation
statin
pharmaceutical combinations
treatment
Prior art date
Application number
TNTNSN98158A
Other languages
English (en)
Inventor
Buch Jan
Andrew Donald Scott Robert
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22011309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN98158(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN98158A1 publication Critical patent/TNSN98158A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)

Abstract

L'INVENTION CONCERNE DES ASSOCIATIONS PHARMACEUTIQUES D'AMLODIPINE OU D'UN DES SES SELS D'ADDITION D'ACIDE PHARMACEUTIQUEMENT ACCEPTABLES ET D'UNE STATINE OU DE SES SELS PHARMACEUTIQUEMENT ACCEPTABLES. ELLE CONCERNE EGALEMENT UN PROCEDE POUR LA PREPARATION D'ASSOCIATIONS DE COMPOSITIONS PHARMACEUTIQUES AINSI QUE DES KITS CONTENANT CELLES-CI. APPLICATION : UTILISATION POUR LE TRAITEMENT DE SUJETS SOUFFRANT D'ANGINE DE POITRINE, D'ATHEROSCLEROSE, D'HYPERTENSION ET D'HYPERLIPIDEMIE EN ASSOCIATION, ET POUR LE TRAITEMENT DE SUJETS PRESENTANT DES SYMPTOMES DE RISQUES CARDIAQUES.
TNTNSN98158A 1997-08-29 1998-08-26 Associations pharmaceutiques d'amlodipine et d'une statine, et procede pour leur preparation TNSN98158A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5755597P 1997-08-29 1997-08-29

Publications (1)

Publication Number Publication Date
TNSN98158A1 true TNSN98158A1 (fr) 2005-03-15

Family

ID=22011309

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98158A TNSN98158A1 (fr) 1997-08-29 1998-08-26 Associations pharmaceutiques d'amlodipine et d'une statine, et procede pour leur preparation

Country Status (36)

Country Link
US (1) US20020025981A1 (fr)
EP (1) EP1003507A1 (fr)
JP (1) JP2001514224A (fr)
KR (1) KR20010022385A (fr)
CN (1) CN1117566C (fr)
AP (1) AP1207A (fr)
AR (1) AR017514A1 (fr)
AU (1) AU744982B2 (fr)
BG (1) BG104076A (fr)
BR (1) BR9811558A (fr)
CA (1) CA2296726C (fr)
CO (1) CO4970726A1 (fr)
DZ (1) DZ2600A1 (fr)
EA (1) EA002705B1 (fr)
GT (1) GT199800134A (fr)
HN (1) HN1998000124A (fr)
HR (1) HRP980475A2 (fr)
HU (1) HUP0003103A3 (fr)
ID (1) ID24275A (fr)
IL (2) IL133957A0 (fr)
IS (1) IS5345A (fr)
MA (1) MA26539A1 (fr)
NO (1) NO20000999L (fr)
NZ (1) NZ502283A (fr)
OA (1) OA11289A (fr)
PA (1) PA8457201A1 (fr)
PE (1) PE106999A1 (fr)
PL (1) PL339088A1 (fr)
SA (1) SA98190432A (fr)
SK (1) SK1392000A3 (fr)
TN (1) TNSN98158A1 (fr)
TR (1) TR200000562T2 (fr)
UY (1) UY25159A1 (fr)
WO (1) WO1999011263A1 (fr)
YU (1) YU2700A (fr)
ZA (1) ZA987843B (fr)

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
WO1993023069A1 (fr) 1992-05-19 1993-11-25 Graham Edmund Kelly Complements benefiques pour la sante, contenant des phyto-×strogenes, des analogues ou des metabolites de ceux-ci
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
AUPO203996A0 (en) 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
WO2000038721A1 (fr) 1998-12-23 2000-07-06 G.D. Searle Llc Combinaisons d'inhibiteurs de la proteine de transfert du cholesteryle-ester et de derives de l'acide nicotinique utilisees dans le cadre de troubles cardio-vasculaires
EP1076091A1 (fr) * 1999-08-09 2001-02-14 Universite Catholique De Louvain Composé ou composition pharmaceutique pour la prévention et/ou le traitement d'ischémie cardiaque, de maladies vasculaires périphériques, de tumeurs et de plaies
AUPQ266199A0 (en) 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
DE19944803A1 (de) * 1999-09-20 2001-03-29 Bayer Ag Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln
AU2001284413A1 (en) * 2000-08-30 2002-03-13 Sankyo Company Limited Medicinal compositions for preventing or treating heart failure
AUPR255401A0 (en) * 2001-01-16 2001-02-08 Novogen Research Pty Ltd Regulation of lipids and/or bone density and compositions therefor
AUPR363301A0 (en) 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20030114497A1 (en) * 2001-07-31 2003-06-19 Laman Alani Pharmaceutical compositions of amlodipine and atorvastatin
WO2003061604A2 (fr) 2002-01-17 2003-07-31 Pharmacia Corporation Nouveaux composes d'alkyl/aryl hydroxy ou cetothiepine servant d'inhibiteurs du transport des acides biliaires de type ileal et de l'absorption de taurocholate
NL1019882C2 (nl) * 2002-02-01 2003-08-04 Synthon Licensing Amlodipine vrije base.
US20040053842A1 (en) * 2002-07-02 2004-03-18 Pfizer Inc. Methods of treatment with CETP inhibitors and antihypertensive agents
US7071210B2 (en) * 2002-07-02 2006-07-04 Pfizer Inc. CETP inhibitors in combination with antihypertensive agents and uses thereof
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
WO2005097191A2 (fr) * 2004-04-04 2005-10-20 Sepracor Inc. Combinaisons comprenant de la (s)-amlodipine et un inhibiteur de la hmg-coa reductase ou un inhibiteur de l'absorption de cholesterol ou les deux a la fois et methodes permettant de reduire l'hypertension
KR100582347B1 (ko) * 2004-12-30 2006-05-22 한미약품 주식회사 3-하이드록시-3-메틸글루타릴 조효소 a 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법
KR100742432B1 (ko) 2005-12-27 2007-07-24 한미약품 주식회사 암로디핀 캠실레이트 및 심바스타틴을 포함하는 복합제제,및 이의 제조방법
CN101415425B (zh) 2006-03-29 2014-11-26 兴和株式会社 甘油三酯降低剂和高胰岛素血症改善剂
WO2008023869A1 (fr) * 2006-08-24 2008-02-28 Hanall Pharmaceutical Co., Ltd. PRÉPARATION PHARMACEUTIQUE COMBINÉE À LIBÉRATION CONTRÔLÉE COMPRENANT DES INHIBITEURS CALCIQUES À BASE DE DIHYDROPYRIDINE ET DES INHIBITEURS DE HMG-CoA RÉDUCTASE
WO2008023958A1 (fr) * 2006-08-24 2008-02-28 Hanall Pharmaceutical Co., Ltd. Composition pharmaceutique combinée à libération contrôlée comprenant de la dihydropyridine, des bloqueurs de canal calcium et des inhibiteurs de l'hgm-coa réductase
MX2007008440A (es) * 2007-07-11 2009-02-18 Senosiain S A De C V Lab Composicion farmaceutica combinada.
KR101207618B1 (ko) * 2008-02-22 2012-12-04 한올바이오파마주식회사 심혈관계 질환 치료용 약제학적 제제
WO2009125987A2 (fr) * 2008-04-10 2009-10-15 한올제약주식회사 Préparation pharmaceutique
WO2010008203A2 (fr) * 2008-07-15 2010-01-21 한올제약주식회사 Preparation pharmaceutique contenant un inhibiteur des canaux calciques
CN101804055B (zh) * 2010-04-27 2012-01-25 施慧达药业集团(吉林)有限公司 复方药物制剂
US20190263888A1 (en) 2010-10-19 2019-08-29 Op-T Llc Therapeutic peptides and methods for treating autoimmune related disease
EP3253382B1 (fr) 2015-02-06 2021-11-17 Intercept Pharmaceuticals, Inc. Compositions pharmaceutiques pour thérapie combinée
WO2019094581A1 (fr) * 2017-11-10 2019-05-16 Op-T Llc Procédés de prévention, de modulation et/ou de réduction d'une maladie cardiovasculaire
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
US12377045B2 (en) 2019-11-25 2025-08-05 Fordoz Pharma Corp. Oral liquid formulations of lipid-lowering and blood pressure-lowering drugs
EP4135742A2 (fr) 2020-04-17 2023-02-22 Op-T Llc Peptides bioactifs et leurs méthodes d'utilisation
CN112826937B (zh) * 2021-03-25 2022-03-22 山东大学齐鲁医院 艾地苯醌与他汀类药物联用在防治动脉粥样硬化中的应用

Family Cites Families (2)

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IN176897B (fr) * 1993-10-29 1996-09-28 Cadila Lab Ltd
DE19539363A1 (de) * 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von festen Arzneiformen

Also Published As

Publication number Publication date
KR20010022385A (ko) 2001-03-15
SA98190432A (ar) 2005-12-03
GT199800134A (es) 2000-02-08
HN1998000124A (es) 1999-02-09
WO1999011263A1 (fr) 1999-03-11
HK1029530A1 (en) 2001-04-06
ID24275A (id) 2000-07-13
CO4970726A1 (es) 2000-11-07
EP1003507A1 (fr) 2000-05-31
CN1117566C (zh) 2003-08-13
AP9801333A0 (en) 1998-09-30
PA8457201A1 (es) 2000-05-24
CN1268054A (zh) 2000-09-27
IL133957A0 (en) 2001-04-30
IS5345A (is) 2000-01-14
YU2700A (sh) 2002-06-19
UY25159A1 (es) 2000-12-29
HUP0003103A3 (en) 2002-03-28
EA200000013A1 (ru) 2000-08-28
SK1392000A3 (en) 2000-08-14
CA2296726A1 (fr) 1999-03-11
US20020025981A1 (en) 2002-02-28
HUP0003103A2 (hu) 2001-01-29
NO20000999D0 (no) 2000-02-28
NZ502283A (en) 2002-05-31
ZA987843B (en) 2000-02-28
DZ2600A1 (fr) 2003-03-01
HRP980475A2 (en) 1999-06-30
MA26539A1 (fr) 2004-12-20
OA11289A (en) 2003-08-25
PE106999A1 (es) 1999-11-06
EA002705B1 (ru) 2002-08-29
NO20000999L (no) 2000-02-28
AU8458598A (en) 1999-03-22
IL133957A (en) 2006-06-11
AU744982B2 (en) 2002-03-07
AP1207A (en) 2003-09-20
TR200000562T2 (tr) 2000-08-21
BG104076A (en) 2000-09-29
CA2296726C (fr) 2004-06-29
PL339088A1 (en) 2000-12-04
BR9811558A (pt) 2000-08-22
AR017514A1 (es) 2001-09-12
JP2001514224A (ja) 2001-09-11

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