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SV2011003834A - Composiciones y metodos para anticuerpos que se dirigen a la proteina de complemento c5 - Google Patents

Composiciones y metodos para anticuerpos que se dirigen a la proteina de complemento c5

Info

Publication number
SV2011003834A
SV2011003834A SV2011003834A SV2011003834A SV2011003834A SV 2011003834 A SV2011003834 A SV 2011003834A SV 2011003834 A SV2011003834 A SV 2011003834A SV 2011003834 A SV2011003834 A SV 2011003834A SV 2011003834 A SV2011003834 A SV 2011003834A
Authority
SV
El Salvador
Prior art keywords
antibodies
compositions
methods
going
complement protein
Prior art date
Application number
SV2011003834A
Other languages
English (en)
Inventor
Beate Diefenbach-Streiber
Adina Eberth
Braydon Charles Guild
Yong-In Kim
Micahel Roguska
Igor Splawski
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SV2011003834A publication Critical patent/SV2011003834A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A ANTICUERPOS QUE SE DIRIGEN A LA PROTEÍNA DE COMPLEMENTO C5, Y A COMPOSICIONES Y MÉTODOS DE USO DE LOS MISMOS
SV2011003834A 2008-08-05 2011-02-07 Composiciones y metodos para anticuerpos que se dirigen a la proteina de complemento c5 SV2011003834A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8635508P 2008-08-05 2008-08-05

Publications (1)

Publication Number Publication Date
SV2011003834A true SV2011003834A (es) 2011-03-23

Family

ID=41227252

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2011003834A SV2011003834A (es) 2008-08-05 2011-02-07 Composiciones y metodos para anticuerpos que se dirigen a la proteina de complemento c5

Country Status (38)

Country Link
US (5) US8241628B2 (es)
EP (3) EP2328616B1 (es)
JP (2) JP5815403B2 (es)
KR (1) KR101463296B1 (es)
CN (2) CN102170906B (es)
AR (1) AR072897A1 (es)
AU (1) AU2009279197B2 (es)
BR (1) BRPI0916668B1 (es)
CA (1) CA2732782C (es)
CL (1) CL2011000233A1 (es)
CO (1) CO6351750A2 (es)
CR (2) CR20110035A (es)
CU (1) CU23978B1 (es)
DK (1) DK2328616T3 (es)
EA (1) EA027575B1 (es)
EC (1) ECSP11010805A (es)
ES (2) ES2643411T3 (es)
HK (1) HK1203156A1 (es)
HN (1) HN2011000357A (es)
HR (1) HRP20150799T1 (es)
HU (1) HUE026179T2 (es)
IL (1) IL210768B (es)
JO (1) JO3118B1 (es)
MA (1) MA32535B1 (es)
MX (2) MX2011001371A (es)
MY (1) MY159396A (es)
NZ (2) NZ590634A (es)
PE (1) PE20110225A1 (es)
PL (1) PL2328616T3 (es)
PT (1) PT2328616E (es)
RS (1) RS54113B1 (es)
SG (1) SG10201405377XA (es)
SI (1) SI2328616T1 (es)
SV (1) SV2011003834A (es)
TW (2) TWI417107B (es)
UA (1) UA105009C2 (es)
WO (1) WO2010015608A1 (es)
ZA (1) ZA201100375B (es)

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