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SV1999000049A - Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv - Google Patents

Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv

Info

Publication number
SV1999000049A
SV1999000049A SV1999000049A SV1999000049A SV1999000049A SV 1999000049 A SV1999000049 A SV 1999000049A SV 1999000049 A SV1999000049 A SV 1999000049A SV 1999000049 A SV1999000049 A SV 1999000049A SV 1999000049 A SV1999000049 A SV 1999000049A
Authority
SV
El Salvador
Prior art keywords
substituted
diethydropyrimidines
new
heterociclicamente
ref
Prior art date
Application number
SV1999000049A
Other languages
English (en)
Inventor
Siegfried Goldmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV1999000049A publication Critical patent/SV1999000049A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVAS DIHIDROPIRIMIDINAS 2 HETEROCICLICAMENTE SUSTITUIDAS, A MEDICAMENTOS QUE CONTIENEN ESTAS DIHIDROPIRIMIDINAS 2 HETEROCICLICAMENTE SUSTITUIDAS, ASI COMO A UN PROCEDIMIENTO PARA LA PREPARACION DE MEDICAMENTOS. AL INVENCION SE REFIERE ADEMAS AL USO DE DIHIDROPIRIMIDINAS 2 HETEROCICLICAMENTE SUSTITUIDAS PARA LA PREPARACION DE UN MEDICAMENTO, EN ESPECIAL PARA EL TRATAMIENTO DE ENFERMEDADES VIRICAS AGUDAS O CRONICAS, ESPECIALMENTE PARA LA PREPARACION DE UN MEDICAMENTO PARA EL TRATAMIENTO DE INFECCIONES AGUDAS O CRONICAS POR HEPATITIS B.
SV1999000049A 1998-04-18 1999-04-16 Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv SV1999000049A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19817262A DE19817262A1 (de) 1998-04-18 1998-04-18 Neue 2-heterocyclisch substituierte Dihydropyrimidine

Publications (1)

Publication Number Publication Date
SV1999000049A true SV1999000049A (es) 2000-07-04

Family

ID=7864971

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1999000049A SV1999000049A (es) 1998-04-18 1999-04-16 Nuevas dihidropirimidinas 2 heterociclicamente sustituidas ref. lea 32793-sv

Country Status (15)

Country Link
US (1) US6503913B1 (es)
EP (1) EP1073653B1 (es)
JP (1) JP2002512244A (es)
KR (1) KR20010042787A (es)
CN (1) CN1134434C (es)
AR (1) AR015765A1 (es)
AU (1) AU3420599A (es)
CA (1) CA2328876A1 (es)
DE (2) DE19817262A1 (es)
ES (1) ES2181413T3 (es)
GT (1) GT199900055A (es)
ID (1) ID26308A (es)
PE (1) PE20000428A1 (es)
SV (1) SV1999000049A (es)
WO (1) WO1999054329A1 (es)

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DE10012824A1 (de) * 2000-03-16 2001-09-20 Bayer Ag Arzneimittel gegen virale Erkrankungen
DE10012823A1 (de) 2000-03-16 2001-09-20 Bayer Ag Arzneimittel gegen virale Erkrankungen
DE10013125A1 (de) * 2000-03-17 2001-09-20 Bayer Ag Arzneimittel gegen virale Erkrankungen
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CN101104604B (zh) 2006-07-10 2011-03-02 北京摩力克科技有限公司 光学纯二氢嘧啶类化合物及其用于制备治疗和预防病毒性疾病的药物的用途
CN100453542C (zh) * 2007-04-30 2009-01-21 广东东阳光药业有限公司 2-杂环取代的二氢嘧啶消旋化合物的拆分方法
CN101328170B (zh) * 2007-06-18 2011-09-14 张中能 一种氟苯基-取代噻唑二氢嘧啶
CN101328168B (zh) * 2007-06-18 2011-09-07 张中能 一种乙氧碳酰基-取代噻唑二氢嘧啶
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WO2010069147A1 (zh) * 2008-12-17 2010-06-24 张中能 二氢嘧啶类化合物、其组合物及其应用
AR089671A1 (es) * 2012-01-06 2014-09-10 Janssen R & D Ireland 1,4-dihidropirimidinas 4,4-disustituidas y su uso como medicamentos para el tratamiento de la hepatitis b
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US20130267517A1 (en) 2012-03-31 2013-10-10 Hoffmann-La Roche Inc. Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
KR20140143160A (ko) * 2012-03-31 2014-12-15 에프. 호프만-라 로슈 아게 B형 간염 바이러스 감염의 치료 및 예방을 위한 신규한 4-메틸-다이하이드로피리미딘
PL2888241T3 (pl) 2012-08-24 2017-12-29 Sunshine Lake Pharma Co., Ltd. 2,4,5,6-Podstawione pochodne 3,6-dihydropirymidyny jako inhibitory polimerazy wirusa zapalenia wątroby typu B (HBV) do leczenia np. przewlekłego zapalenia wątroby
CN103664925B (zh) * 2012-09-07 2018-01-23 广东东阳光药业有限公司 杂芳基取代的二氢嘧啶类化合物及其在药物中的应用
BR112015004113A2 (pt) 2012-09-10 2017-07-04 Hoffmann La Roche 6-aminoácido heteroarila diidropirimidinas para o tratamento e profilaxia da infecção pelo vírus da hepatite b
MX2016006564A (es) 2013-11-19 2017-09-12 Sunshine Lake Pharma Co Ltd Compuestos dihidropirimidina y su aplicacion en productos farmaceuticos.
KR102284938B1 (ko) * 2013-11-27 2021-08-02 선샤인 레이크 파르마 컴퍼니 리미티드 다이하이드로피리미딘 유도체 및 이의 중간산물의 제조 방법
MX2016012573A (es) 2014-03-28 2018-02-19 Sunshine Lake Pharma Co Ltd Compuestos de dihidropirimidina y su aplicacion en productos farmaceuticos.
TW201629054A (zh) 2015-02-07 2016-08-16 廣東東陽光藥業有限公司 二氫嘧啶衍生物的複合物及其在藥物中的應用
WO2016161268A1 (en) 2015-04-01 2016-10-06 Enanta Pharmaceuticals, Inc. Hepatitis b antviral agents
US10738035B2 (en) 2015-05-13 2020-08-11 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US10179131B2 (en) * 2015-07-13 2019-01-15 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
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CN107501257B (zh) * 2017-08-17 2020-05-29 山东大学 二氢嘧啶-三氮唑类衍生物及其制备方法与应用
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KR20210065965A (ko) 2018-09-21 2021-06-04 이난타 파마슈티칼스, 인코포레이티드 항바이러스제로서 작용화된 헤테로사이클
SG11202105007TA (en) 2018-11-21 2021-06-29 Enanta Pharm Inc Functionalized heterocycles as antiviral agents
JP7703449B2 (ja) 2019-03-14 2025-07-07 スミトモ・ファーマ・アメリカ・インコーポレイテッド イソクロマニル化合物の塩およびその結晶体、ならびにそれらの製造方法、治療用途および医薬組成物
US11236111B2 (en) 2019-06-03 2022-02-01 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
WO2020247575A1 (en) 2019-06-04 2020-12-10 Enanta Pharmaceuticals, Inc. Hepatitis b antiviral agents
WO2020247561A1 (en) 2019-06-04 2020-12-10 Enanta Pharmaceuticals, Inc, Hepatitis b antiviral agents
WO2021007488A1 (en) 2019-07-11 2021-01-14 Enanta Pharmaceuticals, Inc. Substituted heterocycles as antiviral agents
AU2020316351A1 (en) 2019-07-19 2022-02-17 Reata Pharmaceuticals, Inc. C17 polar-substituted heteroaromatic synthetic triterpenoids and methods of use thereof
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Also Published As

Publication number Publication date
EP1073653B1 (de) 2002-08-28
CA2328876A1 (en) 1999-10-28
HK1037188A1 (en) 2002-02-01
JP2002512244A (ja) 2002-04-23
AR015765A1 (es) 2001-05-16
GT199900055A (es) 2000-10-07
KR20010042787A (ko) 2001-05-25
WO1999054329A1 (de) 1999-10-28
US6503913B1 (en) 2003-01-07
CN1297449A (zh) 2001-05-30
DE59902470D1 (de) 2002-10-02
AU3420599A (en) 1999-11-08
ID26308A (id) 2000-12-14
CN1134434C (zh) 2004-01-14
PE20000428A1 (es) 2000-06-25
EP1073653A1 (de) 2001-02-07
ES2181413T3 (es) 2003-02-16
DE19817262A1 (de) 1999-10-21

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