SK284339B6 - Deriváty pyridopyranoazepínu, spôsob ich prípravy, liečivo a farmaceutická kompozícia s ich obsahom - Google Patents

Deriváty pyridopyranoazepínu, spôsob ich prípravy, liečivo a farmaceutická kompozícia s ich obsahom Download PDF

Info

Publication number: SK284339B6
Authority: SK; Slovakia
Prior art keywords: group; alkyl; hydrogen; compound; carbon atoms
Prior art date: 1999-03-05

Application number

SK1242-2001A

Other languages

English (en)

Slovak (sk)

Other versions

SK12422001A3 (sk

Inventor

Fr�D�Ric Galli

Samir Jegham

Alistair Lochead

Axelle Samson

Original Assignee

Sanofi-Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-05

Filing date

2000-03-01

Publication date

2005-02-04

2000-03-01 Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo

2002-04-04 Publication of SK12422001A3 publication Critical patent/SK12422001A3/sk

2005-02-04 Publication of SK284339B6 publication Critical patent/SK284339B6/sk

Links

238000000034 method Methods 0.000 title claims abstract description 13
239000003814 drug Substances 0.000 title claims abstract description 4
238000002360 preparation method Methods 0.000 title claims abstract description 4
239000008194 pharmaceutical composition Substances 0.000 title claims abstract 3
CJNWEJQNKRUGOX-UHFFFAOYSA-N pyrido[1,2]pyrano[3,5-b]azepine Chemical class C1=CC=NC2=CC3=NC=CC=C3OC2=C1 CJNWEJQNKRUGOX-UHFFFAOYSA-N 0.000 title claims description 4
239000000203 mixture Substances 0.000 claims abstract description 24
-1 cyano, hydroxyl Chemical group 0.000 claims abstract description 17
125000000217 alkyl group Chemical group 0.000 claims abstract description 15
229910052739 hydrogen Inorganic materials 0.000 claims abstract description 10
239000001257 hydrogen Substances 0.000 claims abstract description 10
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 7
125000005843 halogen group Chemical group 0.000 claims abstract description 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 7
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims abstract description 7
125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 6
150000003839 salts Chemical class 0.000 claims abstract description 6
239000002253 acid Substances 0.000 claims abstract description 4
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125000001624 naphthyl group Chemical group 0.000 claims abstract description 3
125000004433 nitrogen atom Chemical group N* 0.000 claims abstract description 3
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims abstract description 3
150000002431 hydrogen Chemical group 0.000 claims abstract 2
150000001875 compounds Chemical class 0.000 claims description 63
125000004432 carbon atom Chemical group C* 0.000 claims description 8
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 2
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229910052736 halogen Inorganic materials 0.000 claims description 2
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125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 2
239000000654 additive Substances 0.000 claims 1
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125000002252 acyl group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
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208000020016 psychiatric disease Diseases 0.000 description 1
FVHNEDLBZCSUSN-UHFFFAOYSA-N pyrano[2,3-c]pyrazole Chemical compound O1C=CC=C2C=NN=C21 FVHNEDLBZCSUSN-UHFFFAOYSA-N 0.000 description 1
230000008707 rearrangement Effects 0.000 description 1
230000004044 response Effects 0.000 description 1
238000009938 salting Methods 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
201000000980 schizophrenia Diseases 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
238000007711 solidification Methods 0.000 description 1
230000008023 solidification Effects 0.000 description 1
238000013222 sprague-dawley male rat Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000007940 sugar coated tablet Substances 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000013589 supplement Substances 0.000 description 1
238000002636 symptomatic treatment Methods 0.000 description 1
208000011580 syndromic disease Diseases 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
239000003826 tablet Substances 0.000 description 1
DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
230000006441 vascular event Effects 0.000 description 1
LYTCVQQGCSNFJU-LKGYBJPKSA-N α-bungarotoxin Chemical compound C(/[C@H]1O[C@H]2C[C@H]3O[C@@H](CC(=C)C=O)C[C@H](O)[C@]3(C)O[C@@H]2C[C@@H]1O[C@@H]1C2)=C/C[C@]1(C)O[C@H]1[C@@]2(C)O[C@]2(C)CC[C@@H]3O[C@@H]4C[C@]5(C)O[C@@H]6C(C)=CC(=O)O[C@H]6C[C@H]5O[C@H]4C[C@@H](C)[C@H]3O[C@H]2C1 LYTCVQQGCSNFJU-LKGYBJPKSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
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- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SK1242-2001A 1999-03-05 2000-03-01 Deriváty pyridopyranoazepínu, spôsob ich prípravy, liečivo a farmaceutická kompozícia s ich obsahom SK284339B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9902784A FR2790474B1 (fr)	1999-03-05	1999-03-05	Derives de pyridopyranoazepines, leur preparation et leur application en therapeutique
PCT/FR2000/000502 WO2000053608A1 (fr)	1999-03-05	2000-03-01	Derives de pyridopyranoazepines, leur preparation et leur application en therapeutique

Publications (2)

Publication Number	Publication Date
SK12422001A3 SK12422001A3 (sk)	2002-04-04
SK284339B6 true SK284339B6 (sk)	2005-02-04

Family

ID=9542888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1242-2001A SK284339B6 (sk)	1999-03-05	2000-03-01	Deriváty pyridopyranoazepínu, spôsob ich prípravy, liečivo a farmaceutická kompozícia s ich obsahom

Country Status (37)

Country	Link
US (2)	US6538003B1 (es)
EP (1)	EP1161434B1 (es)
JP (1)	JP4806123B2 (es)
KR (2)	KR100768355B1 (es)
CN (1)	CN1137894C (es)
AR (1)	AR022820A1 (es)
AT (1)	ATE231869T1 (es)
AU (1)	AU764625B2 (es)
BG (1)	BG65211B1 (es)
BR (1)	BR0008763A (es)
CA (1)	CA2372063C (es)
CO (1)	CO5160250A1 (es)
CZ (1)	CZ302259B6 (es)
DE (1)	DE60001307T2 (es)
DK (1)	DK1161434T3 (es)
EE (1)	EE04497B1 (es)
ES (1)	ES2191611T3 (es)
FR (1)	FR2790474B1 (es)
HK (1)	HK1040398B (es)
HR (1)	HRP20010655B1 (es)
HU (1)	HU228671B1 (es)
ID (1)	ID30116A (es)
IL (2)	IL145150A0 (es)
MX (1)	MXPA01008972A (es)
NO (1)	NO327119B1 (es)
NZ (1)	NZ513561A (es)
PE (1)	PE20001543A1 (es)
PL (1)	PL201683B1 (es)
RS (1)	RS49997B (es)
RU (1)	RU2238273C2 (es)
SK (1)	SK284339B6 (es)
TR (1)	TR200102403T2 (es)
TW (1)	TWI222975B (es)
UA (1)	UA61164C2 (es)
UY (1)	UY26048A1 (es)
WO (1)	WO2000053608A1 (es)
ZA (1)	ZA200106811B (es)

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DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
KR20120041739A (ko)	2002-07-18	2012-05-02	사이토스 바이오테크놀로지 아게	합텐-캐리어 컨쥬게이트 및 그의 용도
WO2004052365A2 (en) *	2002-12-06	2004-06-24	North Shore-Long Island Jewish Research Institute	Inhibition of inflamation using alpha 7 receptor-binding cholinergic agonists
US7238715B2 (en) *	2002-12-06	2007-07-03	The Feinstein Institute For Medical Research	Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
US8580842B2 (en)	2003-09-30	2013-11-12	Abbott Gmbh & Co. Kg	Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US8316104B2 (en)	2005-11-15	2012-11-20	California Institute Of Technology	Method and apparatus for collaborative system
US8486979B2 (en) *	2006-12-12	2013-07-16	Abbvie Inc.	1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en)	2006-12-12	2008-07-10	Abbott Laboratories	Pharmaceutical compositions and their methods of use
UY30846A1 (es) *	2006-12-30	2008-07-31	Abbott Gmbh & Amp	Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
US20080255203A1 (en) *	2007-04-12	2008-10-16	Abbott Laboratories	Heterocyclic compounds and their methods of use
US20090076059A1 (en) *	2007-09-19	2009-03-19	Protia, Llc	Deuterium-enriched dianicline
CN101981027B (zh)	2007-12-07	2014-08-06	Abbvie德国有限责任两合公司	氨基甲基取代的羟吲哚衍生物及其用于治疗加压素依赖性疾病的用途
CN102026995B (zh)	2007-12-07	2014-10-29	Abbvie德国有限责任两合公司	5，6-二取代的羟吲哚衍生物和其用途
US8703774B2 (en)	2007-12-07	2014-04-22	AbbVie Deutschland GmbH & Co. KG	Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
BRPI0820668A2 (pt) *	2007-12-07	2017-08-22	Abbott Gmbh & Co Kg	Derivados de oxindol substituídos por 5-halogênio e seu uso para tratar doenças dependentes de vasopressina
US8383657B2 (en) *	2007-12-21	2013-02-26	Abbott Laboratories	Thiazolylidine urea and amide derivatives and methods of use thereof
US20090221648A1 (en) *	2007-12-21	2009-09-03	Abbott Laboratories	Compositions for treatment of cognitive disorders
WO2009146031A1 (en) *	2008-03-31	2009-12-03	University Of South Florida	Methods of treating disease-induced ataxia and non-ataxic imbalance
PE20110711A1 (es)	2008-11-19	2011-10-11	Envivo Pharmaceuticals Inc	Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmaceuticamente aceptables de la misma
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
EP2429518A1 (en) *	2009-05-11	2012-03-21	Envivo Pharmaceuticals, Inc.	Treatment of cognitive disorders with certain alpha-7 nicotinic acid receptors in combination with acetylcholinesterase inhibitors
WO2010138600A2 (en) *	2009-05-29	2010-12-02	Abbott Laboratories	Pharmaceutical compositions for the treatment of pain
MX2012013345A (es)	2010-05-17	2013-02-11	Envivo Pharmaceuticals Inc	Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado.
RU2635522C2 (ru)	2012-05-08	2017-11-13	Форум Фармасьютикалз, Инк.	Способы поддержания, лечения или улучшения когнитивной функции
US9585867B2 (en)	2015-08-06	2017-03-07	Charles Everett Ankner	Cannabinod formulation for the sedation of a human or animal

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JP3008226B2 (ja) *	1991-01-16	2000-02-14	第一製薬株式会社	六環性化合物
GB9301660D0 (en) *	1993-01-28	1993-03-17	Smithkline Beecham Plc	Pharmaceuticals
EP0853621A1 (en) *	1995-09-22	1998-07-22	Novo Nordisk A/S	Novel substituted azacyclic or azabicyclic compounds
FR2761072B1 (fr) *	1997-03-20	1999-04-23	Synthelabo	Derives de 2,3-dihydrofuro[3,2-b]pyridine, leur preparation et leur application en therapeutique
WO1998054189A1 (en) *	1997-05-30	1998-12-03	Neurosearch A/S	Spiro-quinuclidine derivatives, their preparation and use
AR013184A1 (es) *	1997-07-18	2000-12-13	Astrazeneca Ab	Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
SE9900100D0 (sv) *	1999-01-15	1999-01-15	Astra Ab	New compounds

1999
- 1999-03-05 FR FR9902784A patent/FR2790474B1/fr not_active Expired - Fee Related
2000
- 2000-01-03 UA UA2001085808A patent/UA61164C2/uk unknown
- 2000-03-01 CZ CZ20013102A patent/CZ302259B6/cs not_active IP Right Cessation
- 2000-03-01 ID IDW00200101796A patent/ID30116A/id unknown
- 2000-03-01 BR BR0008763-7A patent/BR0008763A/pt not_active Application Discontinuation
- 2000-03-01 HU HU0201753A patent/HU228671B1/hu not_active IP Right Cessation
- 2000-03-01 JP JP2000604044A patent/JP4806123B2/ja not_active Expired - Fee Related
- 2000-03-01 US US09/913,679 patent/US6538003B1/en not_active Expired - Lifetime
- 2000-03-01 KR KR1020017011245A patent/KR100768355B1/ko not_active Expired - Fee Related
- 2000-03-01 CN CNB008046662A patent/CN1137894C/zh not_active Expired - Fee Related
- 2000-03-01 EP EP00907746A patent/EP1161434B1/fr not_active Expired - Lifetime
- 2000-03-01 WO PCT/FR2000/000502 patent/WO2000053608A1/fr not_active Ceased
- 2000-03-01 SK SK1242-2001A patent/SK284339B6/sk not_active IP Right Cessation
- 2000-03-01 DK DK00907746T patent/DK1161434T3/da active
- 2000-03-01 CA CA2372063A patent/CA2372063C/en not_active Expired - Fee Related
- 2000-03-01 AU AU29226/00A patent/AU764625B2/en not_active Ceased
- 2000-03-01 HR HR960321A patent/HRP20010655B1/xx not_active IP Right Cessation
- 2000-03-01 NZ NZ513561A patent/NZ513561A/xx not_active IP Right Cessation
- 2000-03-01 EE EEP200100470A patent/EE04497B1/xx not_active IP Right Cessation
- 2000-03-01 IL IL14515000A patent/IL145150A0/xx active IP Right Grant
- 2000-03-01 KR KR1020077013746A patent/KR20070086359A/ko not_active Withdrawn
- 2000-03-01 PL PL352330A patent/PL201683B1/pl unknown
- 2000-03-01 RS YUP-596/01A patent/RS49997B/sr unknown
- 2000-03-01 DE DE60001307T patent/DE60001307T2/de not_active Expired - Lifetime
- 2000-03-01 ES ES00907746T patent/ES2191611T3/es not_active Expired - Lifetime
- 2000-03-01 MX MXPA01008972A patent/MXPA01008972A/es unknown
- 2000-03-01 AT AT00907746T patent/ATE231869T1/de active
- 2000-03-01 TR TR2001/02403T patent/TR200102403T2/xx unknown
- 2000-03-01 HK HK02101759.7A patent/HK1040398B/zh not_active IP Right Cessation
- 2000-03-01 RU RU2001123126/04A patent/RU2238273C2/ru not_active IP Right Cessation
- 2000-03-01 CO CO00014724A patent/CO5160250A1/es unknown
- 2000-03-03 UY UY26048A patent/UY26048A1/es not_active IP Right Cessation
- 2000-03-03 AR ARP000100942A patent/AR022820A1/es active IP Right Grant
- 2000-03-03 PE PE2000000187A patent/PE20001543A1/es not_active Application Discontinuation
- 2000-03-08 TW TW089103753A patent/TWI222975B/zh not_active IP Right Cessation
2001
- 2001-08-16 BG BG105828A patent/BG65211B1/bg unknown
- 2001-08-17 ZA ZA200106811A patent/ZA200106811B/en unknown
- 2001-08-28 IL IL145150A patent/IL145150A/en not_active IP Right Cessation
- 2001-09-03 NO NO20014270A patent/NO327119B1/no not_active IP Right Cessation
2003
- 2003-02-06 US US10/359,881 patent/US6908927B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR100768355B1 (ko)	2007-10-17
IL145150A (en)	2007-06-03
FR2790474B1 (fr)	2001-04-06
AU764625B2 (en)	2003-08-28
RU2238273C2 (ru)	2004-10-20
CA2372063C (en)	2011-01-11
HRP20010655B1 (en)	2003-06-30
TWI222975B (en)	2004-11-01
UY26048A1 (es)	2000-09-29
PL352330A1 (en)	2003-08-11
HU228671B1 (en)	2013-05-28
US6908927B2 (en)	2005-06-21
ZA200106811B (en)	2002-08-19
MXPA01008972A (es)	2002-03-27
WO2000053608A1 (fr)	2000-09-14
DE60001307D1 (de)	2003-03-06
HUP0201753A3 (en)	2004-12-28
BG105828A (bg)	2002-03-29
HK1040398B (zh)	2003-07-18
DE60001307T2 (de)	2003-12-11
SK12422001A3 (sk)	2002-04-04
CZ302259B6 (cs)	2011-01-19
NO327119B1 (no)	2009-04-27
BR0008763A (pt)	2002-01-02
NO20014270L (no)	2001-11-05
NZ513561A (en)	2003-06-30
AR022820A1 (es)	2002-09-04
TR200102403T2 (tr)	2001-12-21
ES2191611T3 (es)	2003-09-16
EE200100470A (et)	2002-12-16
CN1343208A (zh)	2002-04-03
UA61164C2 (uk)	2003-11-17
YU59601A (sh)	2004-03-12
ATE231869T1 (de)	2003-02-15
JP2002539129A (ja)	2002-11-19
DK1161434T3 (da)	2003-05-26
KR20070086359A (ko)	2007-08-27
EE04497B1 (et)	2005-06-15
HRP20010655A2 (en)	2002-08-31
US6538003B1 (en)	2003-03-25
EP1161434A1 (fr)	2001-12-12
ID30116A (id)	2001-11-08
PL201683B1 (pl)	2009-04-30
IL145150A0 (en)	2002-06-30
CA2372063A1 (en)	2000-09-14
HUP0201753A2 (en)	2002-09-28
PE20001543A1 (es)	2001-03-18
JP4806123B2 (ja)	2011-11-02
KR20010102492A (ko)	2001-11-15
US20030187012A1 (en)	2003-10-02
NO20014270D0 (no)	2001-09-03
FR2790474A1 (fr)	2000-09-08
RS49997B (sr)	2008-09-29
CZ20013102A3 (cs)	2002-01-16
CO5160250A1 (es)	2002-05-30
AU2922600A (en)	2000-09-28
BG65211B1 (bg)	2007-07-31
HK1040398A1 (en)	2002-06-07
EP1161434B1 (fr)	2003-01-29
CN1137894C (zh)	2004-02-11

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