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SI1645558T1 - Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja - Google Patents

Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja

Info

Publication number
SI1645558T1
SI1645558T1 SI200331283T SI200331283T SI1645558T1 SI 1645558 T1 SI1645558 T1 SI 1645558T1 SI 200331283 T SI200331283 T SI 200331283T SI 200331283 T SI200331283 T SI 200331283T SI 1645558 T1 SI1645558 T1 SI 1645558T1
Authority
SI
Slovenia
Prior art keywords
serotonin
piperazinylpyrazines
receptor modulators
ht2c receptor
relates
Prior art date
Application number
SI200331283T
Other languages
English (en)
Inventor
Magnus Cernerud
Helena Lundstrom
Claes Lofstrom
Margit Pelcman
Tom Fleck
Alexander Paptchikhine
Emma Andersson
Alf Nygren
Original Assignee
Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0201881A external-priority patent/SE0201881D0/xx
Priority claimed from SE0202041A external-priority patent/SE0202041D0/xx
Priority claimed from SE0202516A external-priority patent/SE0202516D0/xx
Application filed by Biovitrum Ab Publ filed Critical Biovitrum Ab Publ
Publication of SI1645558T1 publication Critical patent/SI1645558T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Luminescent Compositions (AREA)
SI200331283T 2002-06-19 2003-06-18 Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja SI1645558T1 (sl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (sv) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation
US39065602P 2002-06-21 2002-06-21
SE0202041A SE0202041D0 (sv) 2002-06-28 2002-06-28 Novel process
US40611902P 2002-08-26 2002-08-26
SE0202516A SE0202516D0 (sv) 2002-08-26 2002-08-26 Novel compounds, their use, and preparation
US41670102P 2002-10-07 2002-10-07
EP05023471A EP1645558B1 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as serotonin 5-HT2C receptor modulators

Publications (1)

Publication Number Publication Date
SI1645558T1 true SI1645558T1 (sl) 2008-10-31

Family

ID=30004077

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200330493T SI1529043T1 (sl) 2002-06-19 2003-06-18 Postopek za pripravo 2-metil piperazinskih derivatov
SI200331283T SI1645558T1 (sl) 2002-06-19 2003-06-18 Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200330493T SI1529043T1 (sl) 2002-06-19 2003-06-18 Postopek za pripravo 2-metil piperazinskih derivatov

Country Status (16)

Country Link
EP (2) EP1645558B1 (sl)
JP (4) JP4592417B2 (sl)
CN (1) CN100334082C (sl)
AT (2) ATE398119T1 (sl)
AU (1) AU2003237746B8 (sl)
CA (1) CA2485532C (sl)
CY (1) CY1106225T1 (sl)
DE (2) DE60307286T2 (sl)
DK (2) DK1529043T3 (sl)
ES (2) ES2307102T3 (sl)
HK (1) HK1080079B (sl)
NO (1) NO20050279D0 (sl)
NZ (1) NZ536663A (sl)
PT (2) PT1529043E (sl)
SI (2) SI1529043T1 (sl)
WO (1) WO2004000829A1 (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8685924B2 (en) 2004-08-25 2014-04-01 Takeda Pharmaceutical Company Limited Preventives/remedies for stress urinary incontinence and method of screening the same
JP5528699B2 (ja) 2006-05-16 2014-06-25 武田薬品工業株式会社 縮合複素環化合物およびその用途
RU2464269C2 (ru) 2007-10-16 2012-10-20 Дайити Санкио Компани, Лимитед Пиримидилиндолиновое соединение
JP5520051B2 (ja) 2007-11-15 2014-06-11 武田薬品工業株式会社 縮合ピリジン誘導体およびその用途
DK2442870T3 (da) 2009-06-15 2014-06-30 Takeda Pharmaceutical Pyrazinooxazepin-derivater.
US20120253036A1 (en) 2009-12-11 2012-10-04 Yukinori Nagakura Agent for treating fibromyalgia
GB201304811D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Novel treatment for hypertension
JPWO2019131902A1 (ja) 2017-12-27 2020-12-10 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06306075A (ja) * 1993-04-23 1994-11-01 Sanwa Kagaku Kenkyusho Co Ltd エトキシベンズアミド誘導体
CN1242995C (zh) * 1999-05-21 2006-02-22 比奥维特罗姆股份公司 化合物,它们的用途和制备方法
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa
EA005975B1 (ru) * 2000-11-20 2005-08-25 Биовитрум Аб Соединения пиперазинилпиразинов в качестве антагонистов серотонин 5-ht2 рецептора

Also Published As

Publication number Publication date
NO20050279D0 (no) 2005-01-18
JP2013227336A (ja) 2013-11-07
ATE334980T1 (de) 2006-08-15
PT1529043E (pt) 2006-12-29
JP2005537316A (ja) 2005-12-08
EP1529043B1 (en) 2006-08-02
AU2003237746B8 (en) 2010-01-28
JP5378241B2 (ja) 2013-12-25
HK1080079B (zh) 2008-03-14
SI1529043T1 (sl) 2006-12-31
DK1529043T3 (da) 2006-12-04
EP1645558B1 (en) 2008-06-11
CY1106225T1 (el) 2011-06-08
JP2010120949A (ja) 2010-06-03
DE60307286T2 (de) 2007-10-25
NZ536663A (en) 2007-05-31
DK1645558T3 (da) 2008-10-06
WO2004000829A1 (en) 2003-12-31
ATE398119T1 (de) 2008-07-15
PT1645558E (pt) 2008-07-30
EP1529043A1 (en) 2005-05-11
ES2270051T3 (es) 2007-04-01
DE60321606D1 (de) 2008-07-24
EP1645558A1 (en) 2006-04-12
CN100334082C (zh) 2007-08-29
HK1080079A1 (zh) 2006-04-21
AU2003237746B2 (en) 2009-12-17
AU2003237746A1 (en) 2004-01-06
CA2485532C (en) 2012-03-06
JP4592417B2 (ja) 2010-12-01
JP2013116906A (ja) 2013-06-13
DE60307286D1 (de) 2006-09-14
CN1662523A (zh) 2005-08-31
CA2485532A1 (en) 2003-12-31
ES2307102T3 (es) 2008-11-16

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