DK1645558T3 - Piperazinylpyraziner som serotonin 5-HT2C receptormodulatorer - Google Patents
Piperazinylpyraziner som serotonin 5-HT2C receptormodulatorerInfo
- Publication number
- DK1645558T3 DK1645558T3 DK05023471T DK05023471T DK1645558T3 DK 1645558 T3 DK1645558 T3 DK 1645558T3 DK 05023471 T DK05023471 T DK 05023471T DK 05023471 T DK05023471 T DK 05023471T DK 1645558 T3 DK1645558 T3 DK 1645558T3
- Authority
- DK
- Denmark
- Prior art keywords
- serotonin
- piperazinylpyrazines
- receptor modulators
- ht2c receptor
- relates
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title abstract 4
- 229940076279 serotonin Drugs 0.000 title abstract 2
- HCGFLVDMFDHYJD-UHFFFAOYSA-N 2-piperazin-1-ylpyrazine Chemical class C1CNCCN1C1=CN=CC=N1 HCGFLVDMFDHYJD-UHFFFAOYSA-N 0.000 title 1
- 102000006902 5-HT2C Serotonin Receptor Human genes 0.000 title 1
- 108010072553 5-HT2C Serotonin Receptor Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201881A SE0201881D0 (sv) | 2002-06-19 | 2002-06-19 | Novel compounds, their use, and preparation |
| US39065602P | 2002-06-21 | 2002-06-21 | |
| SE0202041A SE0202041D0 (sv) | 2002-06-28 | 2002-06-28 | Novel process |
| US40611902P | 2002-08-26 | 2002-08-26 | |
| SE0202516A SE0202516D0 (sv) | 2002-08-26 | 2002-08-26 | Novel compounds, their use, and preparation |
| US41670102P | 2002-10-07 | 2002-10-07 | |
| PCT/SE2003/001043 WO2004000829A1 (en) | 2002-06-19 | 2003-06-18 | Novel process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1645558T3 true DK1645558T3 (da) | 2008-10-06 |
Family
ID=30004077
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03736405T DK1529043T3 (da) | 2002-06-19 | 2003-06-18 | Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater |
| DK05023471T DK1645558T3 (da) | 2002-06-19 | 2003-06-18 | Piperazinylpyraziner som serotonin 5-HT2C receptormodulatorer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03736405T DK1529043T3 (da) | 2002-06-19 | 2003-06-18 | Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1645558B1 (da) |
| JP (4) | JP4592417B2 (da) |
| CN (1) | CN100334082C (da) |
| AT (2) | ATE398119T1 (da) |
| AU (1) | AU2003237746B8 (da) |
| CA (1) | CA2485532C (da) |
| CY (1) | CY1106225T1 (da) |
| DE (2) | DE60307286T2 (da) |
| DK (2) | DK1529043T3 (da) |
| ES (2) | ES2307102T3 (da) |
| HK (1) | HK1080079B (da) |
| NO (1) | NO20050279D0 (da) |
| NZ (1) | NZ536663A (da) |
| PT (2) | PT1529043E (da) |
| SI (2) | SI1529043T1 (da) |
| WO (1) | WO2004000829A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8685924B2 (en) | 2004-08-25 | 2014-04-01 | Takeda Pharmaceutical Company Limited | Preventives/remedies for stress urinary incontinence and method of screening the same |
| JP5528699B2 (ja) | 2006-05-16 | 2014-06-25 | 武田薬品工業株式会社 | 縮合複素環化合物およびその用途 |
| RU2464269C2 (ru) | 2007-10-16 | 2012-10-20 | Дайити Санкио Компани, Лимитед | Пиримидилиндолиновое соединение |
| JP5520051B2 (ja) | 2007-11-15 | 2014-06-11 | 武田薬品工業株式会社 | 縮合ピリジン誘導体およびその用途 |
| DK2442870T3 (da) | 2009-06-15 | 2014-06-30 | Takeda Pharmaceutical | Pyrazinooxazepin-derivater. |
| US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
| GB201304811D0 (en) * | 2013-03-15 | 2013-05-01 | Proximagen Ltd | Novel treatment for hypertension |
| JPWO2019131902A1 (ja) | 2017-12-27 | 2020-12-10 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06306075A (ja) * | 1993-04-23 | 1994-11-01 | Sanwa Kagaku Kenkyusho Co Ltd | エトキシベンズアミド誘導体 |
| CN1242995C (zh) * | 1999-05-21 | 2006-02-22 | 比奥维特罗姆股份公司 | 化合物,它们的用途和制备方法 |
| AR032318A1 (es) * | 2000-04-13 | 2003-11-05 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa |
| EA005975B1 (ru) * | 2000-11-20 | 2005-08-25 | Биовитрум Аб | Соединения пиперазинилпиразинов в качестве антагонистов серотонин 5-ht2 рецептора |
-
2003
- 2003-06-18 ES ES05023471T patent/ES2307102T3/es not_active Expired - Lifetime
- 2003-06-18 NZ NZ536663A patent/NZ536663A/en not_active IP Right Cessation
- 2003-06-18 CA CA2485532A patent/CA2485532C/en not_active Expired - Fee Related
- 2003-06-18 PT PT03736405T patent/PT1529043E/pt unknown
- 2003-06-18 PT PT05023471T patent/PT1645558E/pt unknown
- 2003-06-18 SI SI200330493T patent/SI1529043T1/sl unknown
- 2003-06-18 ES ES03736405T patent/ES2270051T3/es not_active Expired - Lifetime
- 2003-06-18 EP EP05023471A patent/EP1645558B1/en not_active Expired - Lifetime
- 2003-06-18 EP EP03736405A patent/EP1529043B1/en not_active Expired - Lifetime
- 2003-06-18 CN CNB038141612A patent/CN100334082C/zh not_active Expired - Fee Related
- 2003-06-18 DE DE60307286T patent/DE60307286T2/de not_active Expired - Lifetime
- 2003-06-18 SI SI200331283T patent/SI1645558T1/sl unknown
- 2003-06-18 AT AT05023471T patent/ATE398119T1/de active
- 2003-06-18 AT AT03736405T patent/ATE334980T1/de active
- 2003-06-18 WO PCT/SE2003/001043 patent/WO2004000829A1/en not_active Ceased
- 2003-06-18 HK HK06100135.0A patent/HK1080079B/zh not_active IP Right Cessation
- 2003-06-18 DK DK03736405T patent/DK1529043T3/da active
- 2003-06-18 AU AU2003237746A patent/AU2003237746B8/en not_active Ceased
- 2003-06-18 DE DE60321606T patent/DE60321606D1/de not_active Expired - Lifetime
- 2003-06-18 JP JP2004530934A patent/JP4592417B2/ja not_active Expired - Fee Related
- 2003-06-18 DK DK05023471T patent/DK1645558T3/da active
-
2005
- 2005-01-18 NO NO20050279A patent/NO20050279D0/no not_active Application Discontinuation
-
2006
- 2006-10-30 CY CY20061101556T patent/CY1106225T1/el unknown
-
2010
- 2010-01-07 JP JP2010002229A patent/JP5378241B2/ja not_active Expired - Fee Related
-
2013
- 2013-02-04 JP JP2013019444A patent/JP2013116906A/ja active Pending
- 2013-07-08 JP JP2013142942A patent/JP2013227336A/ja not_active Withdrawn
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