ATE398119T1 - Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors - Google Patents

Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors

Info

Publication number: ATE398119T1
Authority: AT; Austria
Prior art keywords: serotonin; piperazinylpyrazine; modulators; ht2c receptor; relates
Prior art date: 2002-06-19

Application number

AT05023471T

Other languages

English (en)

Inventor

Magnus Cernerud

Helena Lundstroem

Claes Loefstroem

Margit Pelcman

Tom Fleck

Alexander Paptchikhine

Emma Andersson

Alf Nygren

Original Assignee

Biovitrum Ab Publ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-19

Filing date

2003-06-18

Publication date

2008-07-15

2002-06-19 Priority claimed from SE0201881A external-priority patent/SE0201881D0/xx

2002-06-28 Priority claimed from SE0202041A external-priority patent/SE0202041D0/xx

2002-08-26 Priority claimed from SE0202516A external-priority patent/SE0202516D0/xx

2003-06-18 Application filed by Biovitrum Ab Publ filed Critical Biovitrum Ab Publ

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE398119T1 publication Critical patent/ATE398119T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Luminescent Compositions (AREA)

AT05023471T 2002-06-19 2003-06-18 Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors ATE398119T1 (de)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
SE0201881A SE0201881D0 (sv)	2002-06-19	2002-06-19	Novel compounds, their use, and preparation
US39065602P	2002-06-21	2002-06-21
SE0202041A SE0202041D0 (sv)	2002-06-28	2002-06-28	Novel process
US40611902P	2002-08-26	2002-08-26
SE0202516A SE0202516D0 (sv)	2002-08-26	2002-08-26	Novel compounds, their use, and preparation
US41670102P	2002-10-07	2002-10-07

Publications (1)

Publication Number	Publication Date
ATE398119T1 true ATE398119T1 (de)	2008-07-15

Family

ID=30004077

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT05023471T ATE398119T1 (de)	2002-06-19	2003-06-18	Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors
AT03736405T ATE334980T1 (de)	2002-06-19	2003-06-18	Verfahren zur herstellung von 2-methyl piperazine derivaten.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT03736405T ATE334980T1 (de)	2002-06-19	2003-06-18	Verfahren zur herstellung von 2-methyl piperazine derivaten.

Country Status (16)

Country	Link
EP (2)	EP1645558B1 (de)
JP (4)	JP4592417B2 (de)
CN (1)	CN100334082C (de)
AT (2)	ATE398119T1 (de)
AU (1)	AU2003237746B8 (de)
CA (1)	CA2485532C (de)
CY (1)	CY1106225T1 (de)
DE (2)	DE60307286T2 (de)
DK (2)	DK1529043T3 (de)
ES (2)	ES2307102T3 (de)
HK (1)	HK1080079B (de)
NO (1)	NO20050279D0 (de)
NZ (1)	NZ536663A (de)
PT (2)	PT1529043E (de)
SI (2)	SI1529043T1 (de)
WO (1)	WO2004000829A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8685924B2 (en)	2004-08-25	2014-04-01	Takeda Pharmaceutical Company Limited	Preventives/remedies for stress urinary incontinence and method of screening the same
JP5528699B2 (ja)	2006-05-16	2014-06-25	武田薬品工業株式会社	縮合複素環化合物およびその用途
RU2464269C2 (ru)	2007-10-16	2012-10-20	Дайити Санкио Компани, Лимитед	Пиримидилиндолиновое соединение
JP5520051B2 (ja)	2007-11-15	2014-06-11	武田薬品工業株式会社	縮合ピリジン誘導体およびその用途
DK2442870T3 (da)	2009-06-15	2014-06-30	Takeda Pharmaceutical	Pyrazinooxazepin-derivater.
US20120253036A1 (en)	2009-12-11	2012-10-04	Yukinori Nagakura	Agent for treating fibromyalgia
GB201304811D0 (en) *	2013-03-15	2013-05-01	Proximagen Ltd	Novel treatment for hypertension
JPWO2019131902A1 (ja)	2017-12-27	2020-12-10	武田薬品工業株式会社	腹圧性尿失禁および便失禁の治療薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06306075A (ja) *	1993-04-23	1994-11-01	Sanwa Kagaku Kenkyusho Co Ltd	エトキシベンズアミド誘導体
CN1242995C (zh) *	1999-05-21	2006-02-22	比奥维特罗姆股份公司	化合物,它们的用途和制备方法
AR032318A1 (es) *	2000-04-13	2003-11-05	Pharmacia Corp	Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa
EA005975B1 (ru) *	2000-11-20	2005-08-25	Биовитрум Аб	Соединения пиперазинилпиразинов в качестве антагонистов серотонин 5-ht2 рецептора

2003
- 2003-06-18 ES ES05023471T patent/ES2307102T3/es not_active Expired - Lifetime
- 2003-06-18 NZ NZ536663A patent/NZ536663A/en not_active IP Right Cessation
- 2003-06-18 CA CA2485532A patent/CA2485532C/en not_active Expired - Fee Related
- 2003-06-18 PT PT03736405T patent/PT1529043E/pt unknown
- 2003-06-18 PT PT05023471T patent/PT1645558E/pt unknown
- 2003-06-18 SI SI200330493T patent/SI1529043T1/sl unknown
- 2003-06-18 ES ES03736405T patent/ES2270051T3/es not_active Expired - Lifetime
- 2003-06-18 EP EP05023471A patent/EP1645558B1/de not_active Expired - Lifetime
- 2003-06-18 EP EP03736405A patent/EP1529043B1/de not_active Expired - Lifetime
- 2003-06-18 CN CNB038141612A patent/CN100334082C/zh not_active Expired - Fee Related
- 2003-06-18 DE DE60307286T patent/DE60307286T2/de not_active Expired - Lifetime
- 2003-06-18 SI SI200331283T patent/SI1645558T1/sl unknown
- 2003-06-18 AT AT05023471T patent/ATE398119T1/de active
- 2003-06-18 AT AT03736405T patent/ATE334980T1/de active
- 2003-06-18 WO PCT/SE2003/001043 patent/WO2004000829A1/en not_active Ceased
- 2003-06-18 HK HK06100135.0A patent/HK1080079B/zh not_active IP Right Cessation
- 2003-06-18 DK DK03736405T patent/DK1529043T3/da active
- 2003-06-18 AU AU2003237746A patent/AU2003237746B8/en not_active Ceased
- 2003-06-18 DE DE60321606T patent/DE60321606D1/de not_active Expired - Lifetime
- 2003-06-18 JP JP2004530934A patent/JP4592417B2/ja not_active Expired - Fee Related
- 2003-06-18 DK DK05023471T patent/DK1645558T3/da active
2005
- 2005-01-18 NO NO20050279A patent/NO20050279D0/no not_active Application Discontinuation
2006
- 2006-10-30 CY CY20061101556T patent/CY1106225T1/el unknown
2010
- 2010-01-07 JP JP2010002229A patent/JP5378241B2/ja not_active Expired - Fee Related
2013
- 2013-02-04 JP JP2013019444A patent/JP2013116906A/ja active Pending
- 2013-07-08 JP JP2013142942A patent/JP2013227336A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
NO20050279D0 (no)	2005-01-18
JP2013227336A (ja)	2013-11-07
ATE334980T1 (de)	2006-08-15
PT1529043E (pt)	2006-12-29
JP2005537316A (ja)	2005-12-08
EP1529043B1 (de)	2006-08-02
AU2003237746B8 (en)	2010-01-28
JP5378241B2 (ja)	2013-12-25
HK1080079B (zh)	2008-03-14
SI1529043T1 (sl)	2006-12-31
DK1529043T3 (da)	2006-12-04
EP1645558B1 (de)	2008-06-11
CY1106225T1 (el)	2011-06-08
JP2010120949A (ja)	2010-06-03
DE60307286T2 (de)	2007-10-25
NZ536663A (en)	2007-05-31
DK1645558T3 (da)	2008-10-06
WO2004000829A1 (en)	2003-12-31
PT1645558E (pt)	2008-07-30
EP1529043A1 (de)	2005-05-11
ES2270051T3 (es)	2007-04-01
DE60321606D1 (de)	2008-07-24
EP1645558A1 (de)	2006-04-12
SI1645558T1 (sl)	2008-10-31
CN100334082C (zh)	2007-08-29
HK1080079A1 (zh)	2006-04-21
AU2003237746B2 (en)	2009-12-17
AU2003237746A1 (en)	2004-01-06
CA2485532C (en)	2012-03-06
JP4592417B2 (ja)	2010-12-01
JP2013116906A (ja)	2013-06-13
DE60307286D1 (de)	2006-09-14
CN1662523A (zh)	2005-08-31
CA2485532A1 (en)	2003-12-31
ES2307102T3 (es)	2008-11-16

Publication	Publication Date	Title
BR0311494A (pt)	2005-03-29	Novos indóis substituìdos
SE0303180D0 (sv)	2003-11-26	Novel compounds
SE0302232D0 (sv)	2003-08-18	Novel Compounds
ATE356621T1 (de)	2007-04-15	(s)-2-n-propylamino-5-hydroxytetralin als d3- agonistisches therapeutikum
BRPI0410711A (pt)	2006-06-13	novos compostos
SE0203713D0 (sv)	2002-12-13	Novel compounds
EA200970326A1 (ru)	2009-12-30	Алкильные производные в качестве метаботропных рецепторов глутамата
DK1379246T3 (da)	2009-01-26	Nocieptin-analoger
IL189298A0 (en)	2008-06-05	3.5-disubstituted phenyl-piperidines as modulators of dopamine meurotransmission
NO20063275L (no)	2006-07-14	Anvendelse av substituerte 2-aminotetraliner for forebyggende behandling av Parkinsons sykdom
EA200601194A1 (ru)	2006-10-27	Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
MA33242B1 (fr)	2012-05-02	Composes pour le traitement de troubles metaboliques
SE0401465D0 (sv)	2004-06-08	New substituted piperdines as modulators of dopamine neurotransmission
EA200601895A1 (ru)	2007-04-27	3-(4-гетероарилциклогексиламино)циклопентанкарбоксамиды в качестве модуляторов хемокиновых рецепторов
ATE398119T1 (de)	2008-07-15	Piperazinylpyrazine als modulatoren des serotonin 5-ht2c rezeptors
DE60221813D1 (de)	2007-09-27	Thiazolopyrimidinderivate und deren verwendung als antagonisten des cx3cr1 rezeptors
DE602006014305D1 (de)	2010-06-24	Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptors
BRPI0413158A (pt)	2006-10-03	compostos de n-sulfonil-heterociclo-pirrolil-alquil-aminas como ligantes de 5-hidróxi-triptamina-6
EA200700707A1 (ru)	2007-08-31	Производные 2-ациламинотиазола
ATE418973T1 (de)	2009-01-15	Spirocyclopropyl-amide und -säuren und ihre therapeutischen anwendungen
ATE386519T1 (de)	2008-03-15	Benzimidazole derivate und ihre anwendung als gaba a rezeptor komplex modulatoren
DE602005026965D1 (de)	2011-04-28	Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete aminomethylsubstituierte bicyclische aromatische verbindungen
EA200602080A1 (ru)	2007-04-27	Пиперазиновые производные алкилоксиндолов
ATE498622T1 (de)	2011-03-15	Prolinamidtetrazolderivate als nk3- rezeptorantagonisten
SE0201881D0 (sv)	2002-06-19	Novel compounds, their use, and preparation

Legal Events

Date	Code	Title	Description
2009-02-15	UEP	Publication of translation of european patent specification	Ref document number: 1645558 Country of ref document: EP

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