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SG60050A1 - Process for the preparation of enantiomerically pure cyclo-alkanl-indol-and azaindol-and pyrimido(1,2a) indol-carbocylic acids and their activated derivatives - Google Patents

Process for the preparation of enantiomerically pure cyclo-alkanl-indol-and azaindol-and pyrimido(1,2a) indol-carbocylic acids and their activated derivatives

Info

Publication number
SG60050A1
SG60050A1 SG1997001028A SG1997001028A SG60050A1 SG 60050 A1 SG60050 A1 SG 60050A1 SG 1997001028 A SG1997001028 A SG 1997001028A SG 1997001028 A SG1997001028 A SG 1997001028A SG 60050 A1 SG60050 A1 SG 60050A1
Authority
SG
Singapore
Prior art keywords
indol
alkanl
azaindol
pyrimido
preparation
Prior art date
Application number
SG1997001028A
Other languages
English (en)
Inventor
Jan-Bernd Lenfers
Peter Fey
Paul Naab
Van Kai Laak
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG60050A1 publication Critical patent/SG60050A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG1997001028A 1996-04-04 1997-04-01 Process for the preparation of enantiomerically pure cyclo-alkanl-indol-and azaindol-and pyrimido(1,2a) indol-carbocylic acids and their activated derivatives SG60050A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613549A DE19613549A1 (de) 1996-04-04 1996-04-04 Verfahren zur Herstellung von enantiomerenreinen Cycloalkano-indol- und azaindol-carbonsäuren und deren aktivierte Derivate

Publications (1)

Publication Number Publication Date
SG60050A1 true SG60050A1 (en) 1999-02-22

Family

ID=7790501

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1997001028A SG60050A1 (en) 1996-04-04 1997-04-01 Process for the preparation of enantiomerically pure cyclo-alkanl-indol-and azaindol-and pyrimido(1,2a) indol-carbocylic acids and their activated derivatives

Country Status (27)

Country Link
US (1) US5952498A (fr)
EP (1) EP0799829B1 (fr)
JP (2) JP4235268B2 (fr)
KR (1) KR970069988A (fr)
CN (2) CN1067394C (fr)
AR (2) AR006544A1 (fr)
AT (1) ATE246193T1 (fr)
AU (1) AU722592B2 (fr)
BR (1) BR9701672A (fr)
CA (1) CA2201435C (fr)
CZ (1) CZ102197A3 (fr)
DE (2) DE19613549A1 (fr)
DZ (1) DZ2202A1 (fr)
EE (1) EE9700079A (fr)
ES (1) ES2202506T3 (fr)
HR (1) HRP970178A2 (fr)
HU (1) HU218494B (fr)
ID (1) ID16794A (fr)
IL (1) IL120591A (fr)
MA (1) MA24130A1 (fr)
NO (2) NO308301B1 (fr)
NZ (1) NZ314498A (fr)
PL (1) PL319269A1 (fr)
SG (1) SG60050A1 (fr)
SK (1) SK42897A3 (fr)
TN (1) TNSN97060A1 (fr)
ZA (1) ZA972831B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4435477A1 (de) 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
WO2001074817A1 (fr) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Derives d'hydrazide
WO2005051382A1 (fr) * 2003-11-28 2005-06-09 Astellas Pharma Inc. Agent renforçant l'effet hypolipidemiant
CA2910191C (fr) 2004-03-05 2022-03-08 The Trustees Of The Univeristy Of Pennsylvania L'utilisation d'inhibiteurs mtp pour le traitement a faibles effets secondaires contre des affections liees a l'hyperlipidemie et l'hypercholesterolemie
AU2005230397B2 (en) * 2004-04-09 2010-04-08 Elanco Animal Health Ireland Limited Intermittent dosing regimen for the treatment of overweight with MTP-inhibitors
CA2626461A1 (fr) * 2005-10-18 2007-04-26 Aegerion Pharmaceuticals Methodes de traitement de troubles associees l'hyperlipidemie chez un mammifere
US20080051427A1 (en) * 2006-05-18 2008-02-28 Fritz Schuckler Pharmaceutical Compositions and Methods of Using Same
WO2008079398A1 (fr) * 2006-12-21 2008-07-03 Aegerion Pharmaceuticals, Inc. Procédés de traitement de l'obésité à l'aide d'une combinaison comprenant un inhibiteur de mtp et un inhibiteur de l'absorption du cholestérol
WO2008124384A2 (fr) * 2007-04-03 2008-10-16 Aegerion Pharmaceuticals, Inc. Méthodes de traitement de l'hépatite c
PT2968284T (pt) 2013-03-14 2021-06-28 Osteoqc Inc Derivados alquilamina de harmina para promoção de crescimento ósseo
EP3837241A4 (fr) 2018-08-14 2022-05-18 Osteoqc Inc. COMPOSÉS ß-CARBOLINE FLUORÉS
BR112021002614A2 (pt) 2018-08-14 2021-05-04 Osteoqc Inc. compostos pirrol-dipiridina
AU2021316011A1 (en) 2020-07-29 2023-02-09 Amryt Pharmaceuticals Inc. Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole
DE4435477A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate

Also Published As

Publication number Publication date
EP0799829A1 (fr) 1997-10-08
NZ314498A (en) 1999-09-29
US5952498A (en) 1999-09-14
SK42897A3 (en) 1997-10-08
EP0799829B1 (fr) 2003-07-30
AU1660297A (en) 1997-10-09
JP4235268B2 (ja) 2009-03-11
CZ102197A3 (en) 1997-10-15
AR006544A1 (es) 1999-09-08
NO308301B1 (no) 2000-08-28
DE19613549A1 (de) 1997-10-09
AR012048A2 (es) 2000-09-27
JPH1045759A (ja) 1998-02-17
NO20003784D0 (no) 2000-07-24
CN1184109A (zh) 1998-06-10
CN1330065A (zh) 2002-01-09
CA2201435A1 (fr) 1997-10-04
ID16794A (id) 1997-11-13
PL319269A1 (en) 1997-10-13
ZA972831B (en) 1997-10-31
TNSN97060A1 (fr) 2005-03-15
MA24130A1 (fr) 1997-10-01
ES2202506T3 (es) 2004-04-01
NO971513D0 (no) 1997-04-03
NO20003784L (no) 1997-10-06
ATE246193T1 (de) 2003-08-15
IL120591A0 (en) 1997-08-14
CA2201435C (fr) 2006-12-12
HRP970178A2 (en) 1998-04-30
NO971513L (no) 1997-10-06
DZ2202A1 (fr) 2002-12-03
EE9700079A (et) 1997-10-15
IL120591A (en) 2000-11-21
MX9702446A (es) 1997-10-31
HU218494B (hu) 2000-09-28
DE59710487D1 (de) 2003-09-04
HUP9700698A1 (hu) 1998-01-28
HU9700698D0 (en) 1997-05-28
JP2008169218A (ja) 2008-07-24
AU722592B2 (en) 2000-08-10
KR970069988A (ko) 1997-11-07
BR9701672A (pt) 1998-11-03
CN1067394C (zh) 2001-06-20

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