SG170109A1 - Proteins, nucleic acids and medicaments - Google Patents

Proteins, nucleic acids and medicaments

Info

Publication number: SG170109A1
Authority: SG; Singapore
Prior art keywords: tgf; ss3s; full; wild type; provides
Prior art date: 2006-03-11

Application number

SG201101795-1A

Other languages

English (en)

Inventor

Mark William James Ferguson

Phillip Mellor

Hugh Gerard Laverty

Nick Occleston

Sharon Oaekane

Emma Atkinson

Original Assignee

Renovo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-03-11

Filing date

2007-03-12

Publication date

2011-04-29

2007-03-12 Application filed by Renovo Ltd filed Critical Renovo Ltd

2011-04-29 Publication of SG170109A1 publication Critical patent/SG170109A1/en

Links

239000003814 drug Substances 0.000 title abstract 2
102000039446 nucleic acids Human genes 0.000 title 1
108020004707 nucleic acids Proteins 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 title 1
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
102000056172 Transforming growth factor beta-3 Human genes 0.000 abstract 3
108090000097 Transforming growth factor beta-3 Proteins 0.000 abstract 3
239000012634 fragment Substances 0.000 abstract 3
238000006467 substitution reaction Methods 0.000 abstract 2
ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
102000004887 Transforming Growth Factor beta Human genes 0.000 abstract 1
108090001012 Transforming Growth Factor beta Proteins 0.000 abstract 1
235000001014 amino acid Nutrition 0.000 abstract 1
150000001413 amino acids Chemical group 0.000 abstract 1
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
125000000291 glutamic acid group Chemical group N[C@@H](CCC(O)=O)C(=O)* 0.000 abstract 1
125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physical Education & Sports Medicine (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

SG201101795-1A 2006-03-11 2007-03-12 Proteins, nucleic acids and medicaments SG170109A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0604938.1A GB0604938D0 (en)	2006-03-11	2006-03-11	Proteins, nucleic acids and medicaments

Publications (1)

Publication Number	Publication Date
SG170109A1 true SG170109A1 (en)	2011-04-29

Family

ID=36241443

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG201101795-1A SG170109A1 (en)	2006-03-11	2007-03-12	Proteins, nucleic acids and medicaments

Country Status (16)

Country	Link
US (2)	US7947264B2 (es)
EP (1)	EP2001904A2 (es)
JP (1)	JP2009543542A (es)
KR (1)	KR20080106450A (es)
CN (1)	CN101437846A (es)
AR (1)	AR063947A1 (es)
AU (1)	AU2007226345A1 (es)
BR (1)	BRPI0708785A2 (es)
CA (1)	CA2645344A1 (es)
GB (1)	GB0604938D0 (es)
IL (1)	IL193699A0 (es)
MX (1)	MX2008011705A (es)
NO (1)	NO20084189L (es)
RU (1)	RU2008140119A (es)
SG (1)	SG170109A1 (es)
WO (1)	WO2007104945A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0724203D0 (en) *	2007-12-12	2008-01-23	Renovo Ltd	Methods for the inhibition of scarring
GB0724204D0 (en) *	2007-12-12	2008-01-23	Renovo Ltd	Methods for inhibition of scarring
JP2011228644A (ja)	2010-03-29	2011-11-10	Murata Mfg Co Ltd	電子部品及びその製造方法
CN102657897A (zh) *	2012-05-21	2012-09-12	中国人民解放军第三军医大学第三附属医院	一种载TGF-β3的缓释组织工程膜的制备方法
MY186271A (en)	2015-03-05	2021-07-01	Auckland Uniservices Ltd	Ophthalmic compositions and methods of use therefor

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IL78197A (en)	1985-03-22	1991-07-18	Genentech Inc	Nucleic acid encoding tgf-beta and its uses
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US5135915A (en)	1988-10-14	1992-08-04	Genentech, Inc.	Method for the treatment of grafts prior to transplantation using TGF-.beta.
JPH05501500A (ja)	1989-10-18	1993-03-25	クリエイティブ・バイオマリキュールズ・インコーポレーテッド	ＴＧＦ―βの生合成構築物
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GB9206861D0 (en)	1992-03-28	1992-05-13	Univ Manchester	Wound healing and treatment of fibrotic disorders
WO1993019783A1 (en)	1992-04-01	1993-10-14	The Whittier Institute For Diabetes And Endocrinology	Methods of inhibiting or enhancing scar formation in the cns
US5411940A (en)	1993-09-29	1995-05-02	Alcon Laboratories, Inc.	Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma
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BR9915919A (pt)	1998-10-07	2001-08-21	Syngenta Participations Ag	Proteìnas terapeuticamente ativas em plantas
AU3556400A (en)	1999-03-17	2000-10-04	Novartis Ag	Pharmaceutical compositions
WO2000056879A1 (en)	1999-03-22	2000-09-28	Universität Zürich	TRANSFORMING GROWTH FACTOR (TFG) β SUPERFAMILY ANTAGONISTS
CA2404961A1 (en)	2000-04-03	2001-10-11	Monsanto Technology Llc	Method for producing authentic cytokines in plants
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US20040078851A1 (en)	2000-05-02	2004-04-22	Ning Huang	Production of human growth factors in monocot seeds
DE10026713A1 (de) *	2000-05-30	2001-12-06	Walter Sebald	Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta
AU2001238091A1 (en)	2000-08-09	2002-02-18	Curis, Inc.	Tgf-beta therapeutics, compositions and methods of use
WO2002076494A2 (en)	2001-03-23	2002-10-03	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh	USE OF CYTOKINES OF THE TGF-β SUPERFAMILY FOR THE TREATMENT AND DIAGNOSIS OF SKIN RELATED DISORDERS
US20030033637A1 (en)	2001-06-05	2003-02-13	Croptech Corporation	Gene expression and production of TGF-beta proteins including bioactive mullerian inhibiting substance from plants
KR20050054928A (ko)	2002-09-27	2005-06-10	센트로 데 인제니에리아 제네티카 와이 바이오테크놀로지아	피자식물의 유전자 형질전환 식물의 생산용 벡터
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BRPI0613731A2 (pt)	2005-07-12	2011-02-01	Renovo Ltd	composição farmacêutica, recipiente enchido previamente, bem como uso de um açúcar para aprimorar a recuperação e/ou aumentar a atividade biológica de um membro da superfamìlia tgf-beta
GB0514262D0 (en)	2005-07-12	2005-08-17	Renovo Ltd	Promotion of epithelial regeneration
GB0604964D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Protein folding
GB0604966D0 (en)	2006-03-11	2006-04-19	Renovo Ltd	Medicaments and proteins
GB0617816D0 (en)	2006-09-11	2006-10-18	Renovo Ltd	Nucleic acids and methods of protein expression

2006
- 2006-03-11 GB GBGB0604938.1A patent/GB0604938D0/en not_active Ceased
2007
- 2007-03-12 BR BRPI0708785-3A patent/BRPI0708785A2/pt not_active IP Right Cessation
- 2007-03-12 KR KR1020087023406A patent/KR20080106450A/ko not_active Withdrawn
- 2007-03-12 JP JP2008558882A patent/JP2009543542A/ja active Pending
- 2007-03-12 EP EP07712874A patent/EP2001904A2/en not_active Withdrawn
- 2007-03-12 SG SG201101795-1A patent/SG170109A1/en unknown
- 2007-03-12 AU AU2007226345A patent/AU2007226345A1/en not_active Abandoned
- 2007-03-12 MX MX2008011705A patent/MX2008011705A/es unknown
- 2007-03-12 CN CNA2007800163435A patent/CN101437846A/zh active Pending
- 2007-03-12 WO PCT/GB2007/000833 patent/WO2007104945A2/en not_active Ceased
- 2007-03-12 RU RU2008140119/13A patent/RU2008140119A/ru not_active Application Discontinuation
- 2007-03-12 CA CA002645344A patent/CA2645344A1/en not_active Abandoned
- 2007-03-12 US US12/282,463 patent/US7947264B2/en not_active Expired - Fee Related
- 2007-09-12 AR ARP070104046A patent/AR063947A1/es not_active Application Discontinuation
2008
- 2008-08-26 IL IL193699A patent/IL193699A0/en unknown
- 2008-10-07 NO NO20084189A patent/NO20084189L/no not_active Application Discontinuation
2011
- 2011-01-11 US US13/004,589 patent/US20110105396A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2001904A2 (en)	2008-12-17
CN101437846A (zh)	2009-05-20
NO20084189L (no)	2008-10-07
US20110105396A1 (en)	2011-05-05
US20090105146A1 (en)	2009-04-23
CA2645344A1 (en)	2007-09-20
WO2007104945A2 (en)	2007-09-20
BRPI0708785A2 (pt)	2011-06-14
AR063947A1 (es)	2009-03-04
JP2009543542A (ja)	2009-12-10
RU2008140119A (ru)	2010-04-20
WO2007104945A3 (en)	2008-05-15
KR20080106450A (ko)	2008-12-05
IL193699A0 (en)	2011-08-01
US7947264B2 (en)	2011-05-24
MX2008011705A (es)	2008-09-26
GB0604938D0 (en)	2006-04-19
AU2007226345A1 (en)	2007-09-20

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