SG164375A1 - Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof - Google Patents
Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereofInfo
- Publication number
- SG164375A1 SG164375A1 SG201005244-7A SG2010052447A SG164375A1 SG 164375 A1 SG164375 A1 SG 164375A1 SG 2010052447 A SG2010052447 A SG 2010052447A SG 164375 A1 SG164375 A1 SG 164375A1
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutically acceptable
- manufacturing
- extended release
- acceptable salt
- same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04019249 | 2004-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG164375A1 true SG164375A1 (en) | 2010-09-29 |
Family
ID=34926162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG201005244-7A SG164375A1 (en) | 2004-08-13 | 2005-07-25 | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20060051419A1 (es) |
| EP (3) | EP2431027A1 (es) |
| JP (1) | JP4971159B2 (es) |
| KR (2) | KR20070050081A (es) |
| CN (3) | CN101849920A (es) |
| AU (1) | AU2005271193B2 (es) |
| BR (1) | BRPI0513848A (es) |
| CA (1) | CA2576386A1 (es) |
| EA (2) | EA200700388A1 (es) |
| EC (1) | ECSP077243A (es) |
| EG (1) | EG26209A (es) |
| IL (1) | IL181281A0 (es) |
| MX (1) | MX2007001850A (es) |
| NO (1) | NO20070944L (es) |
| NZ (1) | NZ553645A (es) |
| SG (1) | SG164375A1 (es) |
| UA (3) | UA97084C2 (es) |
| WO (1) | WO2006015943A2 (es) |
| ZA (1) | ZA200700313B (es) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| EP2305252A1 (en) * | 2001-12-11 | 2011-04-06 | University Of Virginia Patent Foundation | Use of pramipexole to treat amyotrophic lateral sclerosis |
| MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| RS52057B2 (sr) * | 2004-08-13 | 2018-03-30 | Boehringer Ingelheim Int | Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so |
| KR20070050081A (ko) | 2004-08-13 | 2007-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 프라미펙솔 또는 약제학적으로 허용되는 이의 염을포함하는 연장 방출형 펠렛 제형, 이의 제조방법 및 이의용도 |
| WO2006046256A1 (en) * | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
| EP1901721A1 (en) * | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Delayed release or extended-delayed release dosage forms of pramipexole |
| EP1901720A2 (en) * | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
| JP2009504748A (ja) * | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | R(+)プラミペキソールを用いた神経回復 |
| WO2007090882A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
| WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
| US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
| WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| CA2648495C (en) * | 2006-04-26 | 2016-07-05 | Alphapharm Pty Ltd | Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix |
| PL2457562T3 (pl) * | 2006-05-09 | 2017-09-29 | Mallinckrodt Llc | Stałe postacie dawkowania leku o zmodyfikowanym uwalnianiu o kinetyce rzędu zerowego |
| EP2497473A1 (en) * | 2006-05-16 | 2012-09-12 | Knopp Neurosciences, Inc. | Therapeutically effective amounts of R(+) and S(-) pramipexole for use in the treatment of Parkinson's disease and pharmaceutical compositions thereof |
| KR20090021169A (ko) * | 2006-05-16 | 2009-02-27 | 크놉 뉴로사이언시스 인코포레이티드 | R(+) 및 s(-) 프라미펙솔을 포함하는 조성물 및 이의 사용 방법 |
| US20080131492A1 (en) * | 2006-06-23 | 2008-06-05 | Spherics, Inc. | Dosage forms for movement disorder treatment |
| RU2009110253A (ru) * | 2006-08-24 | 2010-09-27 | БЁРИНГЕР ИНГЕЛЬХАЙМ ФАРМА ГМБХ УНД Ко. КГ (DE) | Способ приготовления таблеток прамипексолдигидрохлорида, обладающих высокой стабильностью при хранении |
| WO2008062446A2 (en) * | 2006-09-14 | 2008-05-29 | Alembic Limited | An extended release composition of levetiracetam, which exhibits no adverse food effect |
| US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| AU2007338631A1 (en) * | 2006-12-22 | 2008-07-03 | Combinatorx, Incorporated | Pharmaceutical compositions for treatment of parkinson's disease and related disorders |
| AU2008224869A1 (en) * | 2007-03-14 | 2008-09-18 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| JP2010521496A (ja) * | 2007-03-14 | 2010-06-24 | ノップ ニューロサイエンシーズ、インク. | キラル精製置換ベンゾチアゾールジアミンの合成 |
| JP2010525018A (ja) * | 2007-04-24 | 2010-07-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | プラミペキソール又はその医薬的に許容できる塩を含有する徐放性錠剤型製剤との組成物 |
| US20110190356A1 (en) * | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
| CA2749253A1 (en) * | 2009-04-09 | 2010-10-14 | Purdue Pharma | Once-daily oral ir/cr pramipexole formulation |
| WO2010148409A1 (en) * | 2009-06-19 | 2010-12-23 | Knopp Neurosciences, Inc. | Compositions and methods for treating amyotrophic lateral sclerosis |
| WO2011128914A2 (en) * | 2010-04-15 | 2011-10-20 | Cadila Healthcare Limited | Extended release pharmaceutical compositions of pramipexole |
| EP2380560A1 (de) * | 2010-04-22 | 2011-10-26 | ratiopharm GmbH | Pramipexol enthaltende Matrixtablette |
| JP2013526601A (ja) * | 2010-05-24 | 2013-06-24 | ルピン・リミテッド | プラミペキソールの徐放性製剤 |
| KR101307334B1 (ko) * | 2010-07-02 | 2013-09-12 | 주식회사 바이오파마티스 | 프라미펙솔 또는 이의 약학적으로 허용되는 염을 포함하는 안정성이 개선된 서방형 약학 조성물 |
| EP2462925A1 (en) * | 2010-11-12 | 2012-06-13 | Neuraxpharm Arzneimittel GmbH | Pramipexole Dihydrochloride Granulate |
| MX358650B (es) * | 2011-03-21 | 2018-08-30 | Boehringer Ingelheim Int | Preparacion solida con contenido de ambroxol. |
| US9512096B2 (en) | 2011-12-22 | 2016-12-06 | Knopp Biosciences, LLP | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| KR101659983B1 (ko) * | 2012-12-31 | 2016-09-26 | 주식회사 삼양바이오팜 | 용융 압출된 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제 |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| ES3043076T3 (en) | 2013-07-12 | 2025-11-24 | Areteia Therapeutics Inc | Treating elevated levels of eosinophils and/or basophils |
| EP3038467B1 (en) | 2013-08-13 | 2020-07-29 | Knopp Biosciences LLC | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| CN104367562A (zh) * | 2013-08-15 | 2015-02-25 | 上海星泰医药科技有限公司 | 盐酸普拉克索缓释片及制备方法 |
| ITMI20132066A1 (it) * | 2013-12-11 | 2015-06-12 | Farmatron Ltd | Sistemi terapeutici a rilascio modificato per la somministrazione orale di mentolo nel trattamento delle malattie intestinali |
| CN105456216B (zh) * | 2014-08-18 | 2019-11-05 | 江苏神龙药业股份有限公司 | 盐酸普拉克索缓释片剂组合物及其制备方法 |
| CN107106494B (zh) * | 2014-09-15 | 2021-12-21 | 奥菲泽米有限公司 | 阿瑞洛莫制剂 |
| CN104367565A (zh) * | 2014-11-21 | 2015-02-25 | 哈尔滨圣吉药业股份有限公司 | 一种盐酸普拉克索缓释微丸 |
| CN104606162B (zh) * | 2015-01-07 | 2017-03-29 | 海南康虹医药科技开发有限公司 | 一种盐酸普拉克索缓释制剂及其制备方法 |
| CN104784155B (zh) * | 2015-05-15 | 2018-02-23 | 中国药科大学 | 一种盐酸普拉克索组合微丸胶囊及其制备方法 |
| CN117180216A (zh) * | 2023-08-01 | 2023-12-08 | 山东新华制药股份有限公司 | 盐酸普拉克索缓释片及其制备方法 |
Family Cites Families (116)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2887440A (en) * | 1957-08-12 | 1959-05-19 | Dow Chemical Co | Enteric coating |
| US3065143A (en) * | 1960-04-19 | 1962-11-20 | Richardson Merrell Inc | Sustained release tablet |
| NL265428A (es) * | 1960-06-06 | |||
| US3458622A (en) * | 1967-04-07 | 1969-07-29 | Squibb & Sons Inc | Controlled release tablet |
| US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| JPS58403B2 (ja) * | 1975-07-24 | 1983-01-06 | 武田薬品工業株式会社 | L− アスコルビンサンセイザイノ セイゾウホウ |
| US4167558A (en) * | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
| US4140755A (en) * | 1976-02-13 | 1979-02-20 | Hoffmann-La Roche Inc. | Sustained release tablet formulations |
| SE8003805L (sv) * | 1980-05-21 | 1981-11-22 | Haessle Ab | En farmaceutisk beredning med forbettrade utlosningsegenskap |
| CH649215A5 (de) | 1981-04-29 | 1985-05-15 | Hoffmann La Roche | Pharmazeutische praeparate. |
| SE8103843L (sv) * | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
| US4424235A (en) * | 1981-09-14 | 1984-01-03 | Hoffmann-La Roche Inc. | Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor |
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| EP0186087B1 (de) * | 1984-12-22 | 1989-08-23 | Dr. Karl Thomae GmbH | Tetrahydro-benzthiazole, deren Herstellung und deren Verwendung als Zwischenprodukte oder als Arnzneimittel |
| US4738851A (en) * | 1985-09-27 | 1988-04-19 | University Of Iowa Research Foundation, Inc. | Controlled release ophthalmic gel formulation |
| US4666612A (en) * | 1986-03-17 | 1987-05-19 | Kerr-Mcgee Chemical Corporation | Method for recovering a wood preservative from waste sludges |
| US4772473A (en) | 1986-06-16 | 1988-09-20 | Norwich Eaton Pharmaceuticals, Inc. | Nitrofurantoin dosage form |
| US4709712A (en) * | 1986-10-22 | 1987-12-01 | Dermatalogical Products Of Texas | Polycarboxylic acid polymer gels as protective agents |
| US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
| US4789549A (en) * | 1987-03-09 | 1988-12-06 | Warner-Lambert Company | Sustained release dosage forms |
| US4859470A (en) | 1988-06-02 | 1989-08-22 | Alza Corporation | Dosage form for delivering diltiazem |
| GB8828020D0 (en) * | 1988-12-01 | 1989-01-05 | Unilever Plc | Topical composition |
| US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US5007790A (en) * | 1989-04-11 | 1991-04-16 | Depomed Systems, Inc. | Sustained-release oral drug dosage form |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5273975A (en) * | 1989-06-09 | 1993-12-28 | The Upjohn Company | Heterocyclic amines having central nervous system activity |
| HU210264B (en) | 1989-06-09 | 1995-03-28 | Upjohn Co | Process for producing amines of condensed ring-systems containing nitrogen and pharmaceutical compositions containing them |
| JP2813809B2 (ja) * | 1989-06-19 | 1998-10-22 | 武田薬品工業株式会社 | 有核顆粒製剤およびその製造法 |
| FR2653337B1 (fr) | 1989-10-23 | 1992-02-07 | Dow Corning Sa | Element a liberation prolongee et procede pour le fabriquer. |
| IE82916B1 (en) * | 1990-11-02 | 2003-06-11 | Elan Corp Plc | Formulations and their use in the treatment of neurological diseases |
| JPH04234812A (ja) * | 1990-03-16 | 1992-08-24 | Yamanouchi Pharmaceut Co Ltd | 持続性製剤用顆粒 |
| GB9015822D0 (en) | 1990-07-18 | 1990-09-05 | Beecham Group Plc | Compositions |
| US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5656296A (en) * | 1992-04-29 | 1997-08-12 | Warner-Lambert Company | Dual control sustained release drug delivery systems and methods for preparing same |
| US5661171A (en) * | 1992-07-02 | 1997-08-26 | Oramed, Inc. | Controlled release pilocarpine delivery system |
| DK0661045T3 (da) | 1992-09-18 | 2002-10-28 | Yamanouchi Pharma Co Ltd | Hydrogelpræparat med forsinket frigivelse |
| DE4241013A1 (de) * | 1992-12-05 | 1994-06-09 | Boehringer Ingelheim Kg | Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung |
| US5431920A (en) * | 1993-09-21 | 1995-07-11 | Merck Frosst, Canada, Inc. | Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents |
| US5458887A (en) * | 1994-03-02 | 1995-10-17 | Andrx Pharmaceuticals, Inc. | Controlled release tablet formulation |
| JPH07330606A (ja) * | 1994-06-08 | 1995-12-19 | Towa Yakuhin Kk | ニカルジピン持続性製剤用顆粒 |
| US5650420A (en) | 1994-12-15 | 1997-07-22 | Pharmacia & Upjohn Company | Pramipexole as a neuroprotective agent |
| BR9612291A (pt) | 1995-12-27 | 1999-07-13 | Janssen Pharmaceutica Nv | Forma de dosagem sólida bioadesiva |
| US5846971A (en) * | 1996-06-28 | 1998-12-08 | Schering Corporation | Oral antifungal composition |
| GB9619074D0 (en) | 1996-09-12 | 1996-10-23 | Smithkline Beecham Plc | Composition |
| WO1998055107A1 (en) * | 1997-06-06 | 1998-12-10 | Depomed, Inc. | Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs |
| DK1009387T3 (da) | 1997-07-02 | 2006-08-14 | Euro Celtique Sa | Stabiliserede tramadolformuleringer med langvarig frigivelse |
| US5895663A (en) | 1997-07-31 | 1999-04-20 | L. Perrigo Company | Pseudoephedrine hydrochloride extended-release tablets |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| DE69819748T2 (de) * | 1997-09-12 | 2004-09-30 | Columbia Laboratories (Bermuda) Ltd. | Arzneimittel zur behandlung von dysmenorrhöe und verfrühten wehen |
| US6248358B1 (en) * | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| US6624200B2 (en) * | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| JP2001517692A (ja) | 1997-09-29 | 2001-10-09 | インヘール セラピューティック システムズ, インコーポレイテッド | ネブライザにおける使用のための安定化調製物 |
| US6197339B1 (en) * | 1997-09-30 | 2001-03-06 | Pharmacia & Upjohn Company | Sustained release tablet formulation to treat Parkinson's disease |
| US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| US20020013304A1 (en) | 1997-10-28 | 2002-01-31 | Wilson Leland F. | As-needed administration of an androgenic agent to enhance female sexual desire and responsiveness |
| US20020054911A1 (en) * | 2000-05-11 | 2002-05-09 | Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi | Novel oral dosage form for carvedilol |
| GB9802201D0 (en) | 1998-02-03 | 1998-04-01 | Cerestar Holding Bv | Free-flowable directly compressible starch as binder,disintegrant and filler for compresion tablets and hard gelatine capsules |
| KR20010034588A (ko) * | 1998-03-11 | 2001-04-25 | 피터 기딩스 | 조성물 |
| KR20010043612A (ko) | 1998-05-15 | 2001-05-25 | 로렌스 티. 마이젠헬더 | 카베골린 및 프라미펙솔의 신규 용도 및 복합 제제 |
| GB9812426D0 (en) | 1998-06-10 | 1998-08-05 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| US6312728B1 (en) | 1998-07-07 | 2001-11-06 | Cascade Development, Inc. | Sustained release pharmaceutical preparation |
| TW407058B (en) * | 1998-07-17 | 2000-10-01 | Dev Center Biotechnology | Oral cisapride dosage forms with an extended duration |
| US6322819B1 (en) * | 1998-10-21 | 2001-11-27 | Shire Laboratories, Inc. | Oral pulsed dose drug delivery system |
| US6270805B1 (en) | 1998-11-06 | 2001-08-07 | Andrx Pharmaceuticals, Inc. | Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| EE05022B1 (et) * | 1999-03-31 | 2008-06-16 | Janssen Pharmaceutica N.V. | Eelthelatineeritud tärklise kasutamine hüdrofiilses kontrollitud vabanemisega preparaadis ja hüdrofiilne kontrollitud vabanemisega preparaat |
| DE19927688A1 (de) * | 1999-06-17 | 2000-12-21 | Gruenenthal Gmbh | Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac |
| ATE431141T1 (de) * | 1999-07-13 | 2009-05-15 | Alpha Res Group Llc | Zusammensetzungen und verfahren zur behandlung der parkinson-krankheit |
| GB9923045D0 (en) | 1999-09-29 | 1999-12-01 | Novartis Ag | New oral formulations |
| EP1225888A2 (en) | 1999-10-19 | 2002-07-31 | Nps Pharmaceuticals, Inc. | Sustained-release formulations for treating cns-mediated disorders |
| US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| CA2394222A1 (en) * | 1999-12-22 | 2001-06-28 | Pharmacia Corporation | Sustained-release formulation of a cyclooxygenase-2 inhibitor |
| US6467637B2 (en) * | 2000-01-27 | 2002-10-22 | The York Group, Inc. | Death care merchandising system |
| ES2540103T3 (es) * | 2000-02-08 | 2015-07-08 | Euro-Celtique S.A. | Formulaciones orales de agonistas opioides resistentes a manipulaciones indebidas |
| PE20011074A1 (es) * | 2000-02-23 | 2001-10-04 | Upjohn Co | Uso de pramipexol en el tratamiento de trastornos de adiccion |
| NZ520975A (en) * | 2000-02-24 | 2004-03-26 | Upjohn Co | New drug combinations containing a norepinephrine reuptake inhibitor and an antimuscarinic agent for treating nervous system disorders |
| US6955821B2 (en) * | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US6277875B1 (en) | 2000-07-17 | 2001-08-21 | Andrew J. Holman | Use of dopamine D2/D3 receptor agonists to treat fibromyalgia |
| CA2418915A1 (en) * | 2000-08-08 | 2002-02-14 | Teva Pharmaceutical Industries Ltd. | Stable pergolide mesylate and process for making same |
| ES2187249B1 (es) * | 2000-09-18 | 2004-09-16 | Synthon Bv | Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles. |
| SE0004671D0 (sv) * | 2000-12-15 | 2000-12-15 | Amarin Dev Ab | Pharmaceutical formulation |
| RU2325152C2 (ru) | 2001-07-04 | 2008-05-27 | Сан Фармасьютикл Индастриз Лимитид | Удерживаемая в желудке система регулируемой доставки лекарственного средства |
| US20030022875A1 (en) | 2001-07-27 | 2003-01-30 | Wilson Leland F. | As-needed administration of orally active androgenic agents to enhance female sexual desire and responsiveness |
| US20030032661A1 (en) * | 2001-08-02 | 2003-02-13 | Boehringer Ingelheim Pharma Kg | Pramipexole as an anticonvulsant |
| DE10138275A1 (de) | 2001-08-10 | 2003-02-27 | Boehringer Ingelheim Pharma | Verbindungen zur Beseitigung der Anhedonie |
| GB0125088D0 (en) | 2001-10-18 | 2001-12-12 | Smithkline Beecham Cork Ltd | New use |
| BR0215262A (pt) * | 2001-12-20 | 2004-12-28 | Pharmacia Corp | Formas de dosagem com liberação sustentada de ordem zero e processo para a fabricação das mesmas |
| AU2003224649B2 (en) | 2002-03-04 | 2006-09-07 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Sustained release drug formulations containing a carrier peptide |
| KR100784341B1 (ko) * | 2002-04-05 | 2007-12-13 | 유로-셀띠끄 소시에떼 아노님 | 활성 화합물의 지속적, 불변적 및 독립적 방출용 매트릭스 |
| US20030215498A1 (en) * | 2002-05-17 | 2003-11-20 | Harland Ronald S. | Rapidly disintegrating comressed tablets comprising biologically active compounds |
| CA2489295A1 (en) * | 2002-06-27 | 2004-01-08 | Cilag Ag | Spherical pellet containing a water-soluble active ingredient |
| JP4478413B2 (ja) | 2002-07-11 | 2010-06-09 | 武田薬品工業株式会社 | 被覆製剤の製造法 |
| JP2005538105A (ja) * | 2002-07-25 | 2005-12-15 | ファルマシア・コーポレーション | 水不溶性ポリマーおよび水溶性の小孔形成物質からなる2層により被覆された固体剤形の製造方法 |
| MY142204A (en) * | 2002-07-25 | 2010-10-29 | Pharmacia Corp | Pramipexole once-daily dosage form |
| MY136318A (en) * | 2002-07-25 | 2008-09-30 | Pharmacia Corp | Sustained-release tablet composition |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| US20040121010A1 (en) * | 2002-10-25 | 2004-06-24 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| CA2415154C (en) | 2002-12-24 | 2009-06-16 | Biovail Laboratories Inc. | Modified release formulations of selective serotonin re-uptake inhibitors |
| AU2002361495A1 (en) | 2002-12-24 | 2004-07-22 | Lupin Limited | Enteric coated fluoxetine composition |
| AU2003224467A1 (en) | 2003-03-11 | 2004-09-30 | Korea United Pharm, Inc. | Process for the preparing of hardcapsule formulation containing lansoprazole |
| CA2520321A1 (en) * | 2003-04-04 | 2004-10-14 | Pharmacia Corporation | Oral extended release compressed tablets of multiparticulates |
| US20050020589A1 (en) * | 2003-06-18 | 2005-01-27 | Pfizer Inc. | Sustained-release tablet composition comprising a dopamine receptor agonist |
| RS52057B2 (sr) * | 2004-08-13 | 2018-03-30 | Boehringer Ingelheim Int | Formulacija tablete sa produženim oslobađanjem koja sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so |
| KR20070050081A (ko) | 2004-08-13 | 2007-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 프라미펙솔 또는 약제학적으로 허용되는 이의 염을포함하는 연장 방출형 펠렛 제형, 이의 제조방법 및 이의용도 |
| WO2006046256A1 (en) | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
| EP1901720A2 (en) | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
| EP1901721A1 (en) | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Delayed release or extended-delayed release dosage forms of pramipexole |
| JP2009504748A (ja) | 2005-08-15 | 2009-02-05 | ユニバーシティ オブ バージニア パテント ファウンデーション | R(+)プラミペキソールを用いた神経回復 |
| WO2007054976A2 (en) | 2005-11-08 | 2007-05-18 | Panacea Biotec Ltd. | Lipid based controlled release pharmaceutical composition |
| WO2007090882A2 (en) | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
| US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
| WO2007090883A1 (en) | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
| EP1886665A1 (en) * | 2006-08-01 | 2008-02-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Gastro retentive delivery system |
| CL2007002214A1 (es) * | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| KR20090045945A (ko) * | 2006-08-25 | 2009-05-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 제어 방출 시스템 및 이의 제조방법 |
-
2005
- 2005-07-25 KR KR1020077005743A patent/KR20070050081A/ko not_active Abandoned
- 2005-07-25 UA UAA201010396A patent/UA97084C2/ru unknown
- 2005-07-25 WO PCT/EP2005/053609 patent/WO2006015943A2/en not_active Ceased
- 2005-07-25 AU AU2005271193A patent/AU2005271193B2/en not_active Ceased
- 2005-07-25 UA UAA200906587A patent/UA95993C2/ru unknown
- 2005-07-25 BR BRPI0513848-5A patent/BRPI0513848A/pt not_active IP Right Cessation
- 2005-07-25 EA EA200700388A patent/EA200700388A1/ru unknown
- 2005-07-25 MX MX2007001850A patent/MX2007001850A/es active IP Right Grant
- 2005-07-25 EP EP11190711A patent/EP2431027A1/en not_active Withdrawn
- 2005-07-25 JP JP2007525279A patent/JP4971159B2/ja not_active Expired - Fee Related
- 2005-07-25 EP EP11190708A patent/EP2431026A1/en not_active Withdrawn
- 2005-07-25 CA CA002576386A patent/CA2576386A1/en not_active Abandoned
- 2005-07-25 CN CN201010196130A patent/CN101849920A/zh active Pending
- 2005-07-25 KR KR1020127033319A patent/KR20130003040A/ko not_active Abandoned
- 2005-07-25 EP EP05769893.8A patent/EP1778201B1/en not_active Expired - Lifetime
- 2005-07-25 EA EA201001086A patent/EA201001086A1/ru unknown
- 2005-07-25 CN CN201010198667A patent/CN101843597A/zh active Pending
- 2005-07-25 NZ NZ553645A patent/NZ553645A/en not_active IP Right Cessation
- 2005-07-25 CN CN2005800275003A patent/CN101022788B/zh not_active Expired - Fee Related
- 2005-07-25 UA UAA200702473A patent/UA88477C2/ru unknown
- 2005-07-25 SG SG201005244-7A patent/SG164375A1/en unknown
- 2005-08-12 US US11/202,689 patent/US20060051419A1/en not_active Abandoned
-
2007
- 2007-01-11 ZA ZA200700313A patent/ZA200700313B/xx unknown
- 2007-02-11 EG EGPCTNA2007000148A patent/EG26209A/en active
- 2007-02-12 IL IL181281A patent/IL181281A0/en unknown
- 2007-02-13 EC EC2007007243A patent/ECSP077243A/es unknown
- 2007-02-19 NO NO20070944A patent/NO20070944L/no not_active Application Discontinuation
-
2008
- 2008-11-24 US US12/276,610 patent/US20090130197A1/en not_active Abandoned
-
2009
- 2009-12-03 US US12/630,271 patent/US8715728B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG164375A1 (en) | Extended release pellet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof | |
| IL181282A0 (en) | Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof | |
| EP1864665A4 (en) | IMMUNOSUPPRESSIVE AGENT AND ANTI-TUMOR AGENT COMPRISING A HETEROCYCLIC COMPOUND AS ACTIVE INGREDIENT | |
| TWI328576B (en) | Diketohydrazine derivative compound, medicament containing same as active ingredient | |
| IL164302A (en) | Substituted benzazoles, compositions and use thereof in the manufacture of a medicament for the inhibition of raf kinase activity | |
| IL176872A0 (en) | Amide derivatives, process for the preparation thereof and use thereof as an insecticide | |
| MXPA05009508A (es) | Derivados de nicotinamida 6-substituida como antagonistas de receptor opioide. | |
| EP1670472B8 (de) | Aerosolformulierung für die inhalation enthaltend ein antich olinergikum | |
| WO2002100860A3 (fr) | Composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens | |
| WO2002036123A3 (en) | New treatments for restless legs syndrome | |
| AU2003206760A1 (en) | Anticholinergic agents, method for producing the same and use thereof as medicaments | |
| EP1619180A4 (en) | CASR ANTAGONIST | |
| AU2003239389A1 (en) | Opioid receptor antagonists | |
| IL182834A0 (en) | Sulfonamido-macrocycles and the salts thereof, a pharmaceutical composition comprisng these compounds, the method of preparing and the use thereof | |
| HUP0400155A3 (en) | N-phenylarylsulfonamide compound, drug containing the compound as active ingredient, intermediate for the compound, and processes for producing the same | |
| IL180397A0 (en) | Diamine derivatives, fungicidal compositions containing the same, and processes for the preparation thereof | |
| WO2005092304A3 (en) | Antifungal agents | |
| WO2003024933A1 (en) | 2-phenyl-3-heteroarylpropionic acid derivative or salt thereof and medicine containing the same | |
| WO2004058712A3 (en) | Herbicidally active nicotinoyl derivates | |
| WO2004012722A3 (en) | Bicifadine formulation | |
| TW200509980A (en) | Parasiticidal composition | |
| AU2003219574A1 (en) | Controlled release formulation comprising benzimidazole derivatives or pharmaceutically acceptable salts thereof with increased stability and method for preparing the same | |
| TW200733963A (en) | Cough inhibitor | |
| UA89408C2 (ru) | Твердая фармацевтическая композиция пролонгированного высвобождения 1-(2,3,4-триметоксибензил)пиперазина и способ ее получения | |
| IL164901A0 (en) | Optically active beta-aminoketones, optically active 1,3-aminoalcohols and processes for preparing them |