RU2015123748A - Продукты для ухода за полостью рта, содержащие четырехосновный хлорид цинка и триметилглицин - Google Patents
Продукты для ухода за полостью рта, содержащие четырехосновный хлорид цинка и триметилглицин Download PDFInfo
- Publication number
- RU2015123748A RU2015123748A RU2015123748A RU2015123748A RU2015123748A RU 2015123748 A RU2015123748 A RU 2015123748A RU 2015123748 A RU2015123748 A RU 2015123748A RU 2015123748 A RU2015123748 A RU 2015123748A RU 2015123748 A RU2015123748 A RU 2015123748A
- Authority
- RU
- Russia
- Prior art keywords
- composition according
- composition
- tmg
- halide
- reduce
- Prior art date
Links
- 239000011701 zinc Substances 0.000 title claims 9
- 229910052725 zinc Inorganic materials 0.000 title claims 9
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title claims 4
- GEOIQTXXOZPWHP-UHFFFAOYSA-N 2-(dimethylamino)propanoyl chloride Chemical compound CN(C)C(C)C(Cl)=O GEOIQTXXOZPWHP-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 20
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims 7
- -1 zinc halide Chemical class 0.000 claims 7
- 241000894006 Bacteria Species 0.000 claims 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 150000001805 chlorine compounds Chemical group 0.000 claims 2
- 208000002925 dental caries Diseases 0.000 claims 2
- 210000003298 dental enamel Anatomy 0.000 claims 2
- 230000003628 erosive effect Effects 0.000 claims 2
- 208000024693 gingival disease Diseases 0.000 claims 2
- 150000004820 halides Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical class N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 1
- 206010006326 Breath odour Diseases 0.000 claims 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 239000004909 Moisturizer Substances 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 150000001449 anionic compounds Chemical class 0.000 claims 1
- 229920006318 anionic polymer Polymers 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000001680 brushing effect Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229940112822 chewing gum Drugs 0.000 claims 1
- 235000015218 chewing gum Nutrition 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 210000004268 dentin Anatomy 0.000 claims 1
- 201000002170 dentin sensitivity Diseases 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 239000003205 fragrance Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 230000009610 hypersensitivity Effects 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001333 moisturizer Effects 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 229940051866 mouthwash Drugs 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 159000000001 potassium salts Chemical class 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
- 239000011347 resin Substances 0.000 claims 1
- 229920005989 resin Polymers 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (18)
1. Композиция для ухода за полостью рта, содержащая смесь четырехосновного галогенида цинка и триметилглицина (TMG), в свободной форме или в форме перорально приемлемой соли.
2. Композиция по п. 1, в которой галогенид выбран из хлорида, бромида и фторида.
3. Композиция по п. 1 или 2, в которой галогенид представляет собой хлорид.
4. Композиция по п. 1, в которой TMG представлен в форме перорально приемлемой кислотно-аддитивной соли.
5. Композиция по п. 1 или 2, в которой TMG представлен в виде хлористоводородной соли.
6. Композиция по п. 1 или 2, в которой количество цинка составляет 0,05-4% масс.
7. Композиция по п. 1 или 2, в которой четырехосновный галогенид цинка солюбилизирует в составе, но обеспечивает осаждение цинка при использовании и разбавлении слюной и/или при промывании.
8. Композиция по п. 1 или 2, в которой смесь четырехосновного галогенида цинка и TMG получают перед введением в композицию для ухода за полостью рта.
9. Композиция по п. 1 или 2 в форме зубной пасты, геля, жидкости для полоскания рта, порошка, крема, полоски или жевательной резинки.
10. Композиция по п. 1 или 2, дополнительно содержащая эффективное количество источника фторид-ионов.
11. Композиция по п. 1 или 2, содержащая перорально приемлемое основание, содержащее ингредиенты, выбранные из абразивных веществ, буферных веществ, увлажнителей, поверхностно-активных веществ, загустителей, полосок или фрагментов из смолы, освежителей для полости рта, вкусовых веществ, ароматизирующих веществ, окрашивающих веществ, антибактериальных средств, отбеливающих веществ, веществ, которые препятствуют или предотвращают прикрепление бактерий, источников кальция, источников фосфата, перорально приемлемых
солей калия и анионных полимеров, и комбинации двух или более из них.
12. Композиция по п. 1 или 2, в которой рН смеси перед добавлением композиции составляет от рН 5 до рН 6.
13. Композиция по п. 1 для использования для уменьшения и ослабления кислотной эрозии эмали зубов, уменьшения биопленки, образуемой бактериями, и зубного налета, уменьшения неприятного запаха изо рта, уменьшения воспаления десен, подавления развития кариеса и образования полостей и/или снижения повышенной чувствительности дентина.
14. Ионный комплекс, содержащий четырехосновной галогенид цинка, TMG и анионные соединения.
15. Применение четырехосновного галогенида цинка вместе с TMG в производстве продукта для ухода за полостью рта.
16. Способ лечения или уменьшения эрозии зубной эмали, чистки зубов, уменьшения биопленки, образуемой бактериями, и зубного налета, уменьшения воспаления десен, ингибирования кариеса и образования полостей и/или уменьшения повышенной чувствительности дентина, включающий нанесение композиции по любому из пп. 1-13 на зубы.
17. Комплекс четырехосновный галогенид цинка-триметилглицин.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/070528 WO2014098827A1 (en) | 2012-12-19 | 2012-12-19 | Oral care products comprising tetrabasic zinc chloride and trimethylglycine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015123748A true RU2015123748A (ru) | 2017-01-26 |
| RU2634269C2 RU2634269C2 (ru) | 2017-10-24 |
Family
ID=47501522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015123748A RU2634269C2 (ru) | 2012-12-19 | 2012-12-19 | Продукты для ухода за полостью рта, содержащие четырехосновный хлорид цинка и триметилглицин |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9861563B2 (ru) |
| EP (1) | EP2934444B1 (ru) |
| KR (1) | KR20150097552A (ru) |
| CN (1) | CN104853722B (ru) |
| AR (1) | AR094201A1 (ru) |
| AU (1) | AU2012397268B2 (ru) |
| BR (1) | BR112015014453B1 (ru) |
| CA (1) | CA2892468C (ru) |
| IL (1) | IL239424A0 (ru) |
| MX (1) | MX352454B (ru) |
| PH (1) | PH12015501239A1 (ru) |
| RU (1) | RU2634269C2 (ru) |
| TW (1) | TWI513469B (ru) |
| WO (1) | WO2014098827A1 (ru) |
| ZA (1) | ZA201503949B (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10105303B2 (en) * | 2012-12-19 | 2018-10-23 | Colgate-Palmolive Company | Oral care composition comprising zinc amino acid halides |
| PH12015501436B1 (en) | 2012-12-19 | 2022-07-01 | Colgate Palmolive Co | Dentifrice comprising zinc - amino acid complex |
| CN107635568B (zh) | 2015-06-12 | 2021-01-05 | 杰富意矿物股份有限公司 | 皮肤创伤或皮肤粗糙治疗剂 |
| AU2016389266B2 (en) | 2016-01-28 | 2021-07-01 | Kimberly-Clark Worldwide, Inc. | Anti-adherent composition against DNA viruses and method of inhibiting the adherence of DNA viruses to a surface |
| KR101978828B1 (ko) * | 2016-03-21 | 2019-05-15 | 주식회사 엘지생활건강 | 바이오필름 제거용 조성물 |
| GB2565511B (en) | 2016-05-26 | 2022-04-13 | Kimberly Clark Co | Anti-adherent compositions and methods of inhibiting the adherence of microbes to a surface |
| US10952937B2 (en) | 2016-09-28 | 2021-03-23 | Colgate-Palmolive Company | Oral care compositions and dispensing system therefor |
| WO2019125829A1 (en) * | 2017-12-19 | 2019-06-27 | Colgate-Palmolive Company | Oral care compositions |
| RU2760840C1 (ru) * | 2017-12-19 | 2021-11-30 | Колгейт-Палмолив Компани | Композиции для личной гигиены |
| US11117906B2 (en) | 2018-12-21 | 2021-09-14 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| AU2019402083A1 (en) | 2018-12-21 | 2021-06-24 | Colgate-Palmolive Company | Zinc-arginine-halide complex |
| US11091502B2 (en) | 2018-12-21 | 2021-08-17 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| US11229591B2 (en) | 2018-12-21 | 2022-01-25 | Colgate-Palmolive Company | Methods for synthesizing zinc-lysine-chloride complex |
| DE102023103403A1 (de) * | 2023-02-13 | 2024-08-14 | Dr. Kurt Wolff Gmbh & Co. Kg | Mundpflegemittel mit Dimethylglycin |
Family Cites Families (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1538230A (en) | 1921-12-05 | 1925-05-19 | Ernest F Wiederholdt | Insulated spark-plug connecter |
| DE735096C (de) | 1940-12-09 | 1943-05-06 | Ig Farbenindustrie Ag | Verfahren zur Herstellung von Sulfonsaeuren |
| US2527686A (en) | 1945-12-26 | 1950-10-31 | Max H Sandberg | Mouthwash |
| US2503280A (en) | 1947-10-24 | 1950-04-11 | Du Pont | Azo catalysts in preparation of sulfonic acids |
| US2507088A (en) | 1948-01-08 | 1950-05-09 | Du Pont | Sulfoxidation process |
| US2893918A (en) | 1957-04-24 | 1959-07-07 | Harold A Abramson | Deodorant composition |
| FR1247957A (fr) | 1958-09-28 | 1960-12-09 | Ajinomoto Kk | Procédé de séparation continue d'aminoacides racémiques |
| US3320174A (en) | 1964-04-20 | 1967-05-16 | Colgate Palmolive Co | Detergent composition |
| US3372188A (en) | 1965-03-12 | 1968-03-05 | Union Oil Co | Sulfoxidation process in the presence of sulfur trioxide |
| US3538230A (en) | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| US3678154A (en) | 1968-07-01 | 1972-07-18 | Procter & Gamble | Oral compositions for calculus retardation |
| US3535421A (en) | 1968-07-11 | 1970-10-20 | Procter & Gamble | Oral compositions for calculus retardation |
| US3741911A (en) | 1970-12-21 | 1973-06-26 | Hart Chemical Ltd | Phosphate-free detergent composition |
| US3959458A (en) | 1973-02-09 | 1976-05-25 | The Procter & Gamble Company | Oral compositions for calculus retardation |
| US3937807A (en) | 1973-03-06 | 1976-02-10 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| US3862307A (en) | 1973-04-09 | 1975-01-21 | Procter & Gamble | Dentifrices containing a cationic therapeutic agent and improved silica abrasive |
| US3941818A (en) | 1973-08-20 | 1976-03-02 | Zinpro Corporation | 1:1 Zinc methionine complexes |
| US4051234A (en) | 1975-06-06 | 1977-09-27 | The Procter & Gamble Company | Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies |
| US4340583A (en) | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4339432A (en) | 1979-06-20 | 1982-07-13 | Lever Brothers Company | Oral mouthwash containing zinc and glycine |
| CA1139229A (en) | 1979-06-20 | 1983-01-11 | Thomas W. Ritchey | Zinc salt with glycine in oral composition |
| US4316824A (en) | 1980-06-26 | 1982-02-23 | The Procter & Gamble Company | Liquid detergent composition containing alkyl sulfate and alkyl ethoxylated sulfate |
| JPS57158724A (en) | 1981-03-26 | 1982-09-30 | Shiseido Co Ltd | Antimicrobial composition |
| US4565693A (en) | 1981-11-09 | 1986-01-21 | Colgate-Palmolive Company | Deodorant composition |
| US4487757A (en) | 1981-12-28 | 1984-12-11 | Colgate-Palmolive Company | Dispensing container of toothpaste which effervesces during toothbrushing |
| IL64700A0 (en) | 1982-01-01 | 1982-03-31 | Binderman Itzhak | Dental care compositions |
| US4885155A (en) | 1982-06-22 | 1989-12-05 | The Procter & Gamble Company | Anticalculus compositions using pyrophosphate salt |
| DE3238118A1 (de) | 1982-10-14 | 1984-04-19 | Verla-Pharm, Arzneimittelfabrik Apotheker H.J. v. Ehrlich GmbH & Co KG, 8132 Tutzing | Verfahren zur herstellung von komplexverbindungen aus aminodicarbonsaeuren, zweiwertigen metallionen und halogenidionen |
| US4687663B1 (en) | 1983-03-01 | 1997-10-07 | Chesebrough Ponds Usa Co | Dental preparation article and method for storage and delivery thereof |
| GB2179536B (en) | 1984-06-11 | 1988-12-21 | Godfrey Science & Design Inc | Improvement in the flavour of zinc supplements for oral use |
| US4599152A (en) | 1985-05-24 | 1986-07-08 | Albion Laboratories | Pure amino acid chelates |
| US5188821A (en) | 1987-01-30 | 1993-02-23 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
| US5192531A (en) | 1988-12-29 | 1993-03-09 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| US4866161A (en) | 1987-08-24 | 1989-09-12 | University Of South Alabama | Inhibition of tartar deposition by polyanionic/hydrophobic peptides and derivatives thereof which have a clustered block copolymer structure |
| US5004597A (en) | 1987-09-14 | 1991-04-02 | The Procter & Gamble Company | Oral compositions comprising stannous flouride and stannous gluconate |
| US4842847A (en) | 1987-12-21 | 1989-06-27 | The B. F. Goodrich Company | Dental calculus inhibiting compositions |
| US5287539A (en) * | 1988-03-10 | 1994-02-15 | Scientific-Atlanta, Inc. | Interdiction program denial system for jamming audio and video signals |
| US5061815A (en) | 1988-07-06 | 1991-10-29 | Zinpro Corporation | Metal lysine complexes and method for producing metal lysine complexes |
| US5156845A (en) * | 1990-05-04 | 1992-10-20 | Colgate-Palmolive Company | Dry mouth lozenge |
| GB2243775A (en) * | 1990-05-09 | 1991-11-13 | Unilever Plc | Oral compositions |
| JPH0578243A (ja) | 1990-12-11 | 1993-03-30 | Shiseido Co Ltd | 鎮痒剤及び鎮痒組成物 |
| GB9107833D0 (en) | 1991-04-12 | 1991-05-29 | Unilever Plc | Treatment of periodontitis |
| US5643559A (en) | 1991-10-30 | 1997-07-01 | Colgate-Palmolive Company | Deodorant compositions comprising inhibitors of odor-producing axillary bacterial exoenzymes |
| US5504055A (en) | 1994-03-15 | 1996-04-02 | J.H. Biotech, Inc. | Metal amino acid chelate |
| US5707679A (en) | 1994-09-30 | 1998-01-13 | Kemin Industries, Inc. | Metal propionates for use as animal feed supplements |
| EP0740932B1 (en) | 1995-05-03 | 2002-09-04 | Unilever N.V. | Clear gel-type dentifrices |
| US5714447A (en) | 1996-01-24 | 1998-02-03 | Church & Dwight Co., Inc. | Deodorant soap or detergent composition containing a zinc compound and a polyamine |
| US5698724A (en) | 1996-04-30 | 1997-12-16 | Zinpro Corporation | Amino acid metal complexes using hydrolyzed protein as the amino acid source and methods re same |
| US6121315A (en) | 1996-09-20 | 2000-09-19 | Warner-Lambert Company | Oral compositions containing a zinc compound |
| GB9622659D0 (en) | 1996-10-31 | 1997-01-08 | Unilever Plc | Hair treatment composition |
| US5897891A (en) | 1996-11-18 | 1999-04-27 | Godfrey; John C. | Flavorful zinc compositions for oral use incorporating copper |
| FI106923B (fi) | 1997-01-03 | 2001-05-15 | Cultor Ltd Finnsugar Bioproduc | Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa |
| US5993784A (en) | 1997-07-24 | 1999-11-30 | Whitehill Oral Technologies | Low foaming therapeutic toothpastes with improved cleaning and abrasion performance |
| DK176196B1 (da) | 1997-10-07 | 2007-01-08 | Ejvind Jersie Pedersen | Mundhygejnepræparat til behandling af halitosis samt anvendelse af et chelat omfattende en metaliondel og en aminosyredel som en komponent i præparatet |
| US6605289B1 (en) | 1998-06-09 | 2003-08-12 | Embro Research Company, Llc. | Method and composition for the treatment of epidermal irritations and infections |
| US6558710B1 (en) | 1999-06-14 | 2003-05-06 | Helen Rebecca Godfrey | Topical zinc compositions and methods of use |
| US6685920B2 (en) | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
| US7164035B2 (en) | 2000-01-07 | 2007-01-16 | Newsome David A | Zinc-monocysteine complex and method of using zinc-cysteine complexes |
| JP3490950B2 (ja) | 2000-03-15 | 2004-01-26 | 三洋電機株式会社 | ２シリンダ型２段圧縮式ロータリーコンプレッサ |
| DE10160933B4 (de) | 2001-12-12 | 2018-06-21 | Evonik Degussa Gmbh | Zubereitungen mit desodorierender Wirkung, enthaltend das Zinksalz der Ricinolsäure und mindestens eine aminofunktionelle Aminosäure |
| US6670494B1 (en) | 2001-12-17 | 2003-12-30 | J H Brotech, Inc. | Method for preparation of metal organic acid chelates |
| US20040033916A1 (en) | 2002-06-28 | 2004-02-19 | Kuzmin Vladimir Semenovich | Disinfecting composition |
| JP2004175790A (ja) | 2002-11-12 | 2004-06-24 | Arita Junichi | α−グルコシダーゼ阻害作用を有する亜鉛含有物 |
| US7022351B2 (en) | 2003-01-14 | 2006-04-04 | Zinpro Corporation | Composition for supplementing animals with solutions of essential metal amino acid complexes |
| US20040198998A1 (en) | 2003-04-04 | 2004-10-07 | Marian Holerca | Glycine-free antiperspirant salts with betaine for enhanced cosmetic products |
| US7270806B2 (en) | 2004-07-27 | 2007-09-18 | Coty S.A. | Liquid stick antiperspirant |
| US7700079B2 (en) | 2005-09-26 | 2010-04-20 | Jamie Collins Doss | Therapeutic soap product with UV protection |
| EP1954239A2 (en) | 2005-11-29 | 2008-08-13 | The Procter and Gamble Company | Dentifrice composition comprising binder system comprising hydrophilic clay material |
| BRPI0622284A2 (pt) | 2006-05-25 | 2011-03-29 | Yiqiang Huang | processo de obtenção de cloreto básico de zinco utilizado como aditivo micronutriente |
| DE102006040302A1 (de) | 2006-08-29 | 2008-03-20 | Henkel Kgaa | Antitranspirant- und Deodorant-Zusammensetzungen mit verbesserter Pflegewirkung |
| PL1935395T3 (pl) | 2006-12-20 | 2013-11-29 | Unilever Nv | Doustna kompozycja |
| US8247398B2 (en) | 2007-02-17 | 2012-08-21 | Ssv Therapeutics, Inc. | Zinc complexes of natural amino acids for treating elevated copper caused toxicities |
| RU2355420C2 (ru) * | 2007-06-29 | 2009-05-20 | Леонид Леонидович Клопотенко | Зубная паста, содержащая лактулозу, бетаин, хондроитин сульфат и ферменты: папаин, лизоцим, рибонуклеазу и лидазу |
| JP2009084201A (ja) | 2007-09-28 | 2009-04-23 | Riken Koryo Kogyo Kk | パーマネントウェーブ剤用消臭処理剤並びにこれを含有するパーマネントウェーブ剤 |
| WO2009134657A1 (en) * | 2008-04-28 | 2009-11-05 | The Procter & Gamble Company | Oral care compositions |
| EP2293761B1 (en) | 2008-05-12 | 2017-02-01 | Tagra Biotechnologies Ltd | Compositions for topical application comprising microencapsulated colorants |
| US20100021573A1 (en) | 2008-07-22 | 2010-01-28 | Michael J Gonzalez | Compositions and methods for the prevention of cardiovascular disease |
| JP2010132639A (ja) | 2008-11-10 | 2010-06-17 | Nikko Chemical Co Ltd | Ｄｎａ損傷抑制剤及びマトリックスメタロプロテアーゼ−１産生抑制剤 |
| WO2011005577A1 (en) | 2009-06-24 | 2011-01-13 | Soparkar Charles N S | Zinc supplementation to increase responsiveness to metalloprotease therapy |
| CN101606639B (zh) | 2009-07-20 | 2012-07-25 | 曹江山 | 一种保育猪浓缩饲料 |
| AU2009353312B2 (en) | 2009-09-30 | 2013-04-04 | Colgate-Palmolive Company | Antiperspirant/deodorant composition |
| AU2009354789B2 (en) | 2009-10-29 | 2013-06-13 | Colgate-Palmolive Company | Dentifrice comprising stannous fluoride plus zinc citrate and low levels of water |
| AR079890A1 (es) | 2010-01-13 | 2012-02-29 | Colgate Palmolive Co | Estabilizacion de peliculas de oxido de zinc en composiciones bucales |
| SG183905A1 (en) | 2010-03-31 | 2012-10-30 | Colgate Palmolive Co | Oral care composition |
| CN103156073B (zh) | 2011-12-13 | 2015-02-18 | 北京东方联鸣科技发展有限公司 | 奶牛产后营养补充剂 |
| CN103535536A (zh) | 2012-07-15 | 2014-01-29 | 新沂市佳威饲料有限公司 | 一种哺乳母猪饲料的配制方法 |
| WO2014098821A1 (en) | 2012-12-19 | 2014-06-26 | Colgate-Palmolive Company | Method for indicating time for washing or indicating delivery of antibacterial agent |
| RU2638791C2 (ru) | 2012-12-19 | 2017-12-15 | Колгейт-Палмолив Компани | Композиция с галогенидными предшественниками аминокислоты/триметилглицина цинка |
| WO2014098828A1 (en) | 2012-12-19 | 2014-06-26 | Colgate-Palmolive Company | Teeth whitening methods, visually perceptible signals and compositions therefor|comprising zinc amino acid halides |
| RU2628540C2 (ru) | 2012-12-19 | 2017-08-18 | Колгейт-Палмолив Компани | Продукты для ухода за полостью рта, включающие оксид цинка и триметилглицин |
| WO2014098819A1 (en) | 2012-12-19 | 2014-06-26 | Colgate-Palmolive Company | Antiperspirant products with protein and antiperspirant salts |
| RU2621130C2 (ru) | 2012-12-19 | 2017-05-31 | Колгейт-Палмолив Компани | Цинк аминокислота/триметилглицин галогенид |
| WO2014204439A1 (en) | 2013-06-18 | 2014-12-24 | Colgate-Palmolive Company | Zinc amino acid halide complex with cysteine |
| BR112015014478A2 (pt) | 2012-12-19 | 2017-07-11 | Colgate Palmolive Co | complexo de haleto de aminoácido e zinco com cisteína |
| PH12015501436B1 (en) | 2012-12-19 | 2022-07-01 | Colgate Palmolive Co | Dentifrice comprising zinc - amino acid complex |
| US10105303B2 (en) | 2012-12-19 | 2018-10-23 | Colgate-Palmolive Company | Oral care composition comprising zinc amino acid halides |
| CA2892182C (en) | 2012-12-19 | 2020-09-15 | Colgate-Palmolive Company | Zinc-lysine complex |
| MX352357B (es) | 2012-12-19 | 2017-11-22 | Colgate Palmolive Co | Productos para el cuidado oral que contienen un complejo de zinc tetrabásico-aminoácido-halogenuro. |
| MX353019B (es) | 2012-12-19 | 2017-12-18 | Colgate Palmolive Co | Enjuagues bucales de haluros de aminoácidos y zinc. |
| US10494589B2 (en) | 2012-12-19 | 2019-12-03 | Colgate-Palmolive Company | Method for indicating time for washing or indicating delivery of antibacterial agent |
-
2012
- 2012-12-19 US US14/653,876 patent/US9861563B2/en active Active
- 2012-12-19 KR KR1020157016637A patent/KR20150097552A/ko not_active Withdrawn
- 2012-12-19 AU AU2012397268A patent/AU2012397268B2/en not_active Ceased
- 2012-12-19 EP EP12809994.2A patent/EP2934444B1/en active Active
- 2012-12-19 MX MX2015007788A patent/MX352454B/es active IP Right Grant
- 2012-12-19 BR BR112015014453-5A patent/BR112015014453B1/pt not_active IP Right Cessation
- 2012-12-19 CN CN201280077862.3A patent/CN104853722B/zh not_active Expired - Fee Related
- 2012-12-19 RU RU2015123748A patent/RU2634269C2/ru active
- 2012-12-19 WO PCT/US2012/070528 patent/WO2014098827A1/en not_active Ceased
- 2012-12-19 CA CA2892468A patent/CA2892468C/en active Active
-
2013
- 2013-11-28 TW TW102143367A patent/TWI513469B/zh not_active IP Right Cessation
- 2013-12-19 AR ARP130104935A patent/AR094201A1/es unknown
-
2015
- 2015-06-02 ZA ZA2015/03949A patent/ZA201503949B/en unknown
- 2015-06-02 PH PH12015501239A patent/PH12015501239A1/en unknown
- 2015-06-15 IL IL239424A patent/IL239424A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150328096A1 (en) | 2015-11-19 |
| CA2892468C (en) | 2019-10-08 |
| BR112015014453A2 (pt) | 2017-07-11 |
| EP2934444B1 (en) | 2016-11-30 |
| MX2015007788A (es) | 2015-08-20 |
| MX352454B (es) | 2017-11-24 |
| WO2014098827A1 (en) | 2014-06-26 |
| IL239424A0 (en) | 2015-07-30 |
| RU2634269C2 (ru) | 2017-10-24 |
| TW201446277A (zh) | 2014-12-16 |
| CN104853722B (zh) | 2018-07-24 |
| CN104853722A (zh) | 2015-08-19 |
| PH12015501239A1 (en) | 2015-08-17 |
| TWI513469B (zh) | 2015-12-21 |
| KR20150097552A (ko) | 2015-08-26 |
| ZA201503949B (en) | 2017-08-30 |
| CA2892468A1 (en) | 2014-06-26 |
| AR094201A1 (es) | 2015-07-15 |
| BR112015014453B1 (pt) | 2019-06-11 |
| US9861563B2 (en) | 2018-01-09 |
| EP2934444A1 (en) | 2015-10-28 |
| AU2012397268A1 (en) | 2015-06-11 |
| AU2012397268B2 (en) | 2015-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2015123748A (ru) | Продукты для ухода за полостью рта, содержащие четырехосновный хлорид цинка и триметилглицин | |
| RU2015123679A (ru) | Продукты для ухода за полостью рта, содержащие комплекс четырехосновной цинк-аминокислота-галогенид | |
| RU2015123707A (ru) | Продукты для ухода за полостью рта, включающие оксид цинка и триметилглицин | |
| RU2015129106A (ru) | Композиции для ухода за полостью рта, содержащие комплекс цинка с аминокислотой и галогенидом | |
| RU2015123653A (ru) | Гель для ухода за полостью рта, содержащий комплекс цинка и аминокислоты | |
| RU2016148244A (ru) | Средство для ухода за зубами, содержащее комплекс цинка с аминокислотой и фосфаты | |
| JP2011511795A5 (ru) | ||
| RU2015123751A (ru) | Ополаскиватель для полости рта с галогенидом цинка-аминокислоты | |
| RU2015123649A (ru) | Двухкомпонентные композиции, содержащие комплексы аминокислот и галогенидов с цинком и цистеин | |
| RU2010137324A (ru) | Двухкомпонентный продукт для ухода за ротовой полостью | |
| RU2018105782A (ru) | Композиции для ухода за полостью рта и способы их применения | |
| RU2013111534A (ru) | Средство для ухода за полостью рта, способы его применения и производства | |
| RU2017128410A (ru) | Композиции для ухода за полостью рта и способы их применения | |
| GB2499317B (en) | Multicomponent oral care composition | |
| RU2015126796A (ru) | Композиции, содержащие фосфат цинка | |
| JP2014208658A5 (ru) | ||
| JP2011515332A5 (ru) | ||
| RU2010137329A (ru) | Продукт для ухода за полостью рта и способы его применения и получения | |
| RU2013130973A (ru) | Композиции средств для чистки зубов, содержащие силикат кальция и основную аминокислоту | |
| JP2009533344A (ja) | 口腔ケア計画及びキット | |
| RU2014129791A (ru) | Композиции для ухода за полостью рта | |
| RU2013126513A (ru) | Продукт для ухода за полостью рта и способы его применения и получения | |
| RU2010137342A (ru) | Композиции и способы лечения ксеростомии | |
| US20160374904A1 (en) | Sequential Material Deposition for Remineralization and Desensitization of Teeth | |
| RU2016126429A (ru) | Стабилизированные композиции на основе олова (II) |