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PT888114E - Utilizacao de (+)-alfa-(2,3-dimetoxifenil)-1-¬2-(4-fluorofenil)etil|-4-piperidinometanol no tratamento de doencas depressivas e doencas bipolares - Google Patents

Utilizacao de (+)-alfa-(2,3-dimetoxifenil)-1-¬2-(4-fluorofenil)etil|-4-piperidinometanol no tratamento de doencas depressivas e doencas bipolares

Info

Publication number
PT888114E
PT888114E PT97907698T PT97907698T PT888114E PT 888114 E PT888114 E PT 888114E PT 97907698 T PT97907698 T PT 97907698T PT 97907698 T PT97907698 T PT 97907698T PT 888114 E PT888114 E PT 888114E
Authority
PT
Portugal
Prior art keywords
diseases
dimetoxyphenyl
piperidinomethanol
fluorophenyl
alpha
Prior art date
Application number
PT97907698T
Other languages
English (en)
Inventor
Mondadori Dr Cesare
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT888114E publication Critical patent/PT888114E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT97907698T 1996-03-21 1997-02-21 Utilizacao de (+)-alfa-(2,3-dimetoxifenil)-1-¬2-(4-fluorofenil)etil|-4-piperidinometanol no tratamento de doencas depressivas e doencas bipolares PT888114E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96400591A EP0796619A1 (en) 1996-03-21 1996-03-21 Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders

Publications (1)

Publication Number Publication Date
PT888114E true PT888114E (pt) 2002-11-29

Family

ID=8225234

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97907698T PT888114E (pt) 1996-03-21 1997-02-21 Utilizacao de (+)-alfa-(2,3-dimetoxifenil)-1-¬2-(4-fluorofenil)etil|-4-piperidinometanol no tratamento de doencas depressivas e doencas bipolares

Country Status (22)

Country Link
US (2) US6022877A (pt)
EP (2) EP0796619A1 (pt)
JP (1) JP4165906B2 (pt)
KR (1) KR100423018B1 (pt)
CN (1) CN1114406C (pt)
AR (1) AR006281A1 (pt)
AT (1) ATE219672T1 (pt)
AU (1) AU704435B2 (pt)
BR (1) BR9708109A (pt)
CA (1) CA2250077C (pt)
DE (1) DE69713571T2 (pt)
DK (1) DK0888114T3 (pt)
ES (1) ES2175356T3 (pt)
HU (1) HU226675B1 (pt)
IL (1) IL126022A (pt)
NO (2) NO316788B1 (pt)
NZ (1) NZ331448A (pt)
PT (1) PT888114E (pt)
SI (1) SI0888114T1 (pt)
TW (1) TW517048B (pt)
WO (1) WO1997034603A1 (pt)
ZA (1) ZA972345B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0796619A1 (en) * 1996-03-21 1997-09-24 Merrell Pharmaceuticals Inc. Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders
TWI249526B (en) * 1998-03-13 2006-02-21 Aventis Pharma Inc Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
US6713627B2 (en) 1998-03-13 2004-03-30 Aventis Pharmaceuticals Inc. Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
TR200100670T2 (tr) * 1998-08-28 2001-06-21 Aventis Pharmaceuticals Inc. R(+)-alfa-(2,3-Dimetoksifenil)-1- [2-(4-florofenil)etil]-4-piperidinmetanol' ün uyku düzensizlikleri tedavisinde kullanımı.
US6939879B2 (en) 1998-08-28 2005-09-06 Aventis Pharmaceuticals Inc. Use of R (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of substance induced insomnia
US6277864B1 (en) 1998-08-28 2001-08-21 Aventis Pharmaceuticals Inc. Use of R- +)-α-(2,3-dimethoxyphenyl-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol for the treatment of sleep disorders
US20020099076A1 (en) 2000-05-25 2002-07-25 Richard Scheyer D. Use of (+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol or its prodrug in the treatment of symptoms of dementia and dopamine induced psychosis
US20020115695A1 (en) * 2000-11-07 2002-08-22 Paralkar Vishwas M. Combination therapies for the stimulation of bone growth
SK8942003A3 (en) * 2001-01-31 2004-10-05 Pfizer Prod Inc Ether derivatives useful as inhibitors
EP2305645B1 (en) 2008-06-20 2012-05-16 NHWA Pharma.corporation Aralkyl piperidine derivatives and their uses as antalgic or ataractic agent
US8188119B2 (en) * 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783471A (en) * 1985-07-02 1988-11-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine methanol derivatives and the uses thereof
US4912117A (en) * 1985-07-02 1990-03-27 Merrell Dow Pharmaceuticals Inc. Novel chemical compounds
US5169096A (en) * 1985-07-02 1992-12-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl-piperidine-methanol derivatives
US5021428A (en) * 1985-07-02 1991-06-04 Merrell Dow Pharmaceuticals Inc. Novel chemical compounds for the prophylactic treatment of migraine
US4762842A (en) * 1985-10-01 1988-08-09 Eli Lilly And Company Selective method for blocking 5HT2 receptors
US4877798A (en) * 1987-11-23 1989-10-31 Merrell Dow Pharmaceuticals Inc. Treatment of fibromyalgia
JPH02138214A (ja) * 1987-12-10 1990-05-28 Merrell Dow Pharmaceut Inc 不安を治療する方法
US5064838A (en) * 1988-01-21 1991-11-12 Merrell Dow Pharmaceuticals 1,4-disubstituted-piperidinyl compounds as pain relievers
DE3888340T2 (de) * 1988-01-21 1994-06-30 Merrell Dow Pharma Verwendung von 1,4-disubstituierten-Piperidinyl-Verbindungen zur Herstellung eines Arzneimittels zur Behandlung von Schlaflosigkeit.
ZA891901B (en) * 1988-03-17 1989-11-29 Merrell Dow Pharma Method for the treatment of the extrapyramidal side effects associated with neuroleptic therapy
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US5106855A (en) * 1989-12-20 1992-04-21 Merrell Dow Pharmaceuticals Inc. Method for the treatment of glaucoma
DE69105501T2 (de) * 1990-06-01 1995-04-13 Merrell Dow Pharma (+)-alpha-(2,3 dimethoxyphenyl)-1-[2-(fluorophenyl)ethyl]-4-piperidinmethanol.
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
US5618824A (en) * 1994-03-09 1997-04-08 Merrell Pharmaceuticals Inc. Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
KR19990076689A (ko) * 1995-12-22 1999-10-15 피터 지. 스트링거 우울증 치료 방법
EP0796619A1 (en) * 1996-03-21 1997-09-24 Merrell Pharmaceuticals Inc. Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders

Also Published As

Publication number Publication date
SI0888114T1 (en) 2002-10-31
NO984348L (no) 1998-09-18
ATE219672T1 (de) 2002-07-15
CA2250077A1 (en) 1997-09-25
CN1114406C (zh) 2003-07-16
NO316788B1 (no) 2004-05-10
HU226675B1 (en) 2009-06-29
US6022877A (en) 2000-02-08
HUP9902135A2 (hu) 1999-11-29
JP2000506887A (ja) 2000-06-06
BR9708109A (pt) 1999-07-27
TW517048B (en) 2003-01-11
IL126022A (en) 2003-11-23
AR006281A1 (es) 1999-08-11
ES2175356T3 (es) 2002-11-16
AU704435B2 (en) 1999-04-22
DE69713571D1 (de) 2002-08-01
EP0796619A1 (en) 1997-09-24
US6380216B1 (en) 2002-04-30
KR20000064711A (ko) 2000-11-06
WO1997034603A1 (en) 1997-09-25
AU1963197A (en) 1997-10-10
NZ331448A (en) 2000-06-23
HUP9902135A3 (en) 2001-05-28
HK1019702A1 (en) 2000-02-25
DK0888114T3 (da) 2002-10-07
NO984348D0 (no) 1998-09-18
EP0888114B1 (en) 2002-06-26
KR100423018B1 (ko) 2004-05-17
NO20033184L (no) 1998-09-18
IL126022A0 (en) 1999-05-09
CN1213968A (zh) 1999-04-14
ZA972345B (en) 1997-09-25
EP0888114A1 (en) 1999-01-07
DE69713571T2 (de) 2003-02-20
NO20033184D0 (no) 2003-07-11
JP4165906B2 (ja) 2008-10-15
CA2250077C (en) 2003-10-07

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