NO984348D0 - Anvendelse av (+)-<alfa>-(2,3-dimethoxyfenyl)-1-[2-(4-fluor-fenyl)-ethyl]-4-piperidinmethanol ved behandling av depressive sykdommer og bipolare sykdommer - Google Patents

Anvendelse av (+)-<alfa>-(2,3-dimethoxyfenyl)-1-[2-(4-fluor-fenyl)-ethyl]-4-piperidinmethanol ved behandling av depressive sykdommer og bipolare sykdommer

Info

Publication number: NO984348D0
Authority: NO; Norway
Prior art keywords: depressive; dimethoxyphenyl; fluorophenyl; alpha; ethyl
Prior art date: 1996-03-21

Application number

NO984348A

Other languages

English (en)

Other versions

NO316788B1 (no

NO984348L (no

Inventor

Cesare Mondadori

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-21

Filing date

1998-09-18

Publication date

1998-09-18

1998-09-18 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1998-09-18 Publication of NO984348D0 publication Critical patent/NO984348D0/no

1998-09-18 Publication of NO984348L publication Critical patent/NO984348L/no

2004-05-10 Publication of NO316788B1 publication Critical patent/NO316788B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO19984348A 1996-03-21 1998-09-18 Anvendelse av (+)-<alfa>-(2,3-dimethoxyfenyl)-1-[2-(4-fluorfenyl)-ethyl]-4-piperidinmethanol ved behandling av depressive sykdommer NO316788B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP96400591A EP0796619A1 (en)	1996-03-21	1996-03-21	Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders
PCT/US1997/002597 WO1997034603A1 (en)	1996-03-21	1997-02-21	USE OF (+)-α-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL IN TREATING DEPRESSIVE DISORDERS AND BIPOLAR DISORDERS

Publications (3)

Publication Number	Publication Date
NO984348D0 true NO984348D0 (no)	1998-09-18
NO984348L NO984348L (no)	1998-09-18
NO316788B1 NO316788B1 (no)	2004-05-10

Family

ID=8225234

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO19984348A NO316788B1 (no)	1996-03-21	1998-09-18	Anvendelse av (+)-<alfa>-(2,3-dimethoxyfenyl)-1-[2-(4-fluorfenyl)-ethyl]-4-piperidinmethanol ved behandling av depressive sykdommer
NO20033184A NO20033184D0 (no)	1996-03-21	2003-07-11	Anvendelse av forbindelsen (+)-<alfa>-(2,3-dimetoksyfenyl)-1- [2-(4-fluorfenyl)etyl]-4-piperidinmetanol

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20033184A NO20033184D0 (no)	1996-03-21	2003-07-11	Anvendelse av forbindelsen (+)-<alfa>-(2,3-dimetoksyfenyl)-1- [2-(4-fluorfenyl)etyl]-4-piperidinmetanol

Country Status (22)

Country	Link
US (2)	US6022877A (no)
EP (2)	EP0796619A1 (no)
JP (1)	JP4165906B2 (no)
KR (1)	KR100423018B1 (no)
CN (1)	CN1114406C (no)
AR (1)	AR006281A1 (no)
AT (1)	ATE219672T1 (no)
AU (1)	AU704435B2 (no)
BR (1)	BR9708109A (no)
CA (1)	CA2250077C (no)
DE (1)	DE69713571T2 (no)
DK (1)	DK0888114T3 (no)
ES (1)	ES2175356T3 (no)
HU (1)	HU226675B1 (no)
IL (1)	IL126022A (no)
NO (2)	NO316788B1 (no)
NZ (1)	NZ331448A (no)
PT (1)	PT888114E (no)
SI (1)	SI0888114T1 (no)
TW (1)	TW517048B (no)
WO (1)	WO1997034603A1 (no)
ZA (1)	ZA972345B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0796619A1 (en) *	1996-03-21	1997-09-24	Merrell Pharmaceuticals Inc.	Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders
US6713627B2 (en)	1998-03-13	2004-03-30	Aventis Pharmaceuticals Inc.	Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
TWI249526B (en) *	1998-03-13	2006-02-21	Aventis Pharma Inc	Novel processes for the preparation of (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
US6277864B1 (en)	1998-08-28	2001-08-21	Aventis Pharmaceuticals Inc.	Use of R- +)-α-(2,3-dimethoxyphenyl-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol for the treatment of sleep disorders
KR100735513B1 (ko) *	1998-08-28	2007-07-06	아벤티스 파마슈티칼스 인크.	Ｒ(+)-α-(2,3-디메톡시페닐)-1-[2-(4-플루오로페닐)에틸]-4-피페리딘메탄올의 수면 장애 치료용 약제학적 조성물
US6939879B2 (en)	1998-08-28	2005-09-06	Aventis Pharmaceuticals Inc.	Use of R (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of substance induced insomnia
US20020099076A1 (en) *	2000-05-25	2002-07-25	Richard Scheyer D.	Use of (+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol or its prodrug in the treatment of symptoms of dementia and dopamine induced psychosis
US20020161026A1 (en) *	2000-11-07	2002-10-31	Paralkar Vishwas M.	Combination therapies for the stimulation of bone growth
NZ526531A (en) *	2001-01-31	2005-02-25	Pfizer Prod Inc	Ether derivatives useful as inhibitors of phosphodiesterase type IV (PDE4) isozymes
US8501778B2 (en)	2008-06-20	2013-08-06	Nhwa Pharma. Corporation	Aralkyl piperidine derivatives and their uses as antalgic or ataractic agent
US8188119B2 (en) *	2008-10-24	2012-05-29	Eisai R&D Management Co., Ltd	Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4912117A (en) *	1985-07-02	1990-03-27	Merrell Dow Pharmaceuticals Inc.	Novel chemical compounds
US4783471A (en) *	1985-07-02	1988-11-08	Merrell Dow Pharmaceuticals Inc.	N-aralkyl piperidine methanol derivatives and the uses thereof
US5169096A (en) *	1985-07-02	1992-12-08	Merrell Dow Pharmaceuticals Inc.	N-aralkyl-piperidine-methanol derivatives
US5021428A (en) *	1985-07-02	1991-06-04	Merrell Dow Pharmaceuticals Inc.	Novel chemical compounds for the prophylactic treatment of migraine
US4762842A (en) *	1985-10-01	1988-08-09	Eli Lilly And Company	Selective method for blocking 5HT2 receptors
US4877798A (en) *	1987-11-23	1989-10-31	Merrell Dow Pharmaceuticals Inc.	Treatment of fibromyalgia
JPH02138214A (ja) *	1987-12-10	1990-05-28	Merrell Dow Pharmaceut Inc	不安を治療する方法
ATE102482T1 (de) *	1988-01-21	1994-03-15	Merrell Dow Pharma	Verwendung von 1,4-disubstituierten-piperidinyl- verbindungen zur herstellung eines arzneimittels zur behandlung von schlaflosigkeit.
US5064838A (en) *	1988-01-21	1991-11-12	Merrell Dow Pharmaceuticals	1,4-disubstituted-piperidinyl compounds as pain relievers
ZA891901B (en) *	1988-03-17	1989-11-29	Merrell Dow Pharma	Method for the treatment of the extrapyramidal side effects associated with neuroleptic therapy
US4902691A (en) *	1988-12-19	1990-02-20	Eli Lilly And Company	Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US5106855A (en) *	1989-12-20	1992-04-21	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of glaucoma
DK0531410T3 (da) *	1990-06-01	1995-01-30	Merrell Dow Pharma	(+)-alfa-(2,3-Demethoxyphenyl)-1-(2-(4-fluorphenyl)ethyl)-4-piperidinmethanol
US5643784A (en) *	1990-12-04	1997-07-01	H, Lundbeck A/S	Indan derivatives
US5618824A (en) *	1994-03-09	1997-04-08	Merrell Pharmaceuticals Inc.	Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
EP0868185A4 (en) *	1995-12-22	2002-04-10	Lilly Co Eli	METHOD FOR TREATING DEPRESSIONS
EP0796619A1 (en) *	1996-03-21	1997-09-24	Merrell Pharmaceuticals Inc.	Use of (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-4-piperidinemethanol in treating depressive disorders and bipolar disorders

1996
- 1996-03-21 EP EP96400591A patent/EP0796619A1/en not_active Withdrawn
1997
- 1997-02-21 SI SI9730363T patent/SI0888114T1/xx unknown
- 1997-02-21 DK DK97907698T patent/DK0888114T3/da active
- 1997-02-21 BR BR9708109A patent/BR9708109A/pt not_active Application Discontinuation
- 1997-02-21 CN CN97193148A patent/CN1114406C/zh not_active Expired - Fee Related
- 1997-02-21 HU HU9902135A patent/HU226675B1/hu not_active IP Right Cessation
- 1997-02-21 JP JP53346797A patent/JP4165906B2/ja not_active Expired - Fee Related
- 1997-02-21 IL IL12602297A patent/IL126022A/xx not_active IP Right Cessation
- 1997-02-21 PT PT97907698T patent/PT888114E/pt unknown
- 1997-02-21 CA CA002250077A patent/CA2250077C/en not_active Expired - Fee Related
- 1997-02-21 WO PCT/US1997/002597 patent/WO1997034603A1/en not_active Ceased
- 1997-02-21 NZ NZ331448A patent/NZ331448A/en unknown
- 1997-02-21 AU AU19631/97A patent/AU704435B2/en not_active Ceased
- 1997-02-21 DE DE69713571T patent/DE69713571T2/de not_active Expired - Lifetime
- 1997-02-21 AT AT97907698T patent/ATE219672T1/de not_active IP Right Cessation
- 1997-02-21 ES ES97907698T patent/ES2175356T3/es not_active Expired - Lifetime
- 1997-02-21 EP EP97907698A patent/EP0888114B1/en not_active Expired - Lifetime
- 1997-02-21 KR KR10-1998-0707435A patent/KR100423018B1/ko not_active Expired - Fee Related
- 1997-03-17 TW TW086103292A patent/TW517048B/zh not_active IP Right Cessation
- 1997-03-18 ZA ZA9702345A patent/ZA972345B/xx unknown
- 1997-03-19 AR ARP970101085A patent/AR006281A1/es unknown
1998
- 1998-02-19 US US09/026,323 patent/US6022877A/en not_active Expired - Lifetime
- 1998-09-18 NO NO19984348A patent/NO316788B1/no not_active IP Right Cessation
2000
- 2000-10-30 US US09/699,647 patent/US6380216B1/en not_active Expired - Fee Related
2003
- 2003-07-11 NO NO20033184A patent/NO20033184D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE69713571D1 (de)	2002-08-01
JP2000506887A (ja)	2000-06-06
EP0888114A1 (en)	1999-01-07
HK1019702A1 (en)	2000-02-25
EP0888114B1 (en)	2002-06-26
ATE219672T1 (de)	2002-07-15
HU226675B1 (en)	2009-06-29
NO20033184D0 (no)	2003-07-11
JP4165906B2 (ja)	2008-10-15
DK0888114T3 (da)	2002-10-07
AU1963197A (en)	1997-10-10
WO1997034603A1 (en)	1997-09-25
TW517048B (en)	2003-01-11
SI0888114T1 (en)	2002-10-31
AU704435B2 (en)	1999-04-22
US6022877A (en)	2000-02-08
KR20000064711A (ko)	2000-11-06
CA2250077C (en)	2003-10-07
AR006281A1 (es)	1999-08-11
ZA972345B (en)	1997-09-25
PT888114E (pt)	2002-11-29
ES2175356T3 (es)	2002-11-16
CN1114406C (zh)	2003-07-16
IL126022A (en)	2003-11-23
NO316788B1 (no)	2004-05-10
HUP9902135A2 (hu)	1999-11-29
NZ331448A (en)	2000-06-23
NO984348L (no)	1998-09-18
EP0796619A1 (en)	1997-09-24
DE69713571T2 (de)	2003-02-20
KR100423018B1 (ko)	2004-05-17
HUP9902135A3 (en)	2001-05-28
BR9708109A (pt)	1999-07-27
IL126022A0 (en)	1999-05-09
NO20033184L (no)	1998-09-18
CN1213968A (zh)	1999-04-14
US6380216B1 (en)	2002-04-30
CA2250077A1 (en)	1997-09-25

Publication	Publication Date	Title
NO924619D0 (no)	1992-11-30	(+)-alfa-(2,3-dimetoksyfenyl)-1-(2-(4-fluorfenyl)ethyl)-4-piperidinmetanol
IT242435Y1 (it)	2001-06-14	Chiodo per la riduzione delle fratture trocanteriche e del collo delfemore.
NO984348L (no)	1998-09-18	Anvendelse av (+)-<alfa>-(2,3-dimethoxyfenyl)-1-[2-(4-fluor-fenyl)-ethyl]-4-piperidinmethanol ved behandling av depressive sykdommer og bipolare sykdommer
IT243536Y1 (it)	2002-03-05	Apparecchio ortodontico per l'espansione e la contrazione ortodonticae ortopedica del mascellare superiore.
HUP0000873A3 (en)	2002-10-28	The use of levobupivacaine in facial surgery
HUP0000963A3 (en)	2000-10-30	The use of levobupivacaine in paediatric surgery
NO984836D0 (no)	1998-10-16	Substituerte benzylaminer og deres anvendelse for behandling av depresjon
PT925039E (pt)	2002-06-28	Aparelhos para tratamento de ortopedia funcional dento facial e parodontologia
NO20025630L (no)	2003-01-24	Anvendelse av (+)-alfa-(2,3-dimetoksyfenyl)-1-[2-(4- fluorfenyl)etyl]-4-piperidinmetanol eller dets prodrug ved behandling av symptomer pådemens og dopaminindusert psykose
NO20004545D0 (no)	2000-09-12	FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol
BG104914A (en)	2001-10-31	Paroxetine maleate
HUP0202145A3 (en)	2003-02-28	The use of r(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol for the treatment of sleep disorders
NO990303L (no)	1999-03-22	Lipidbindende proteiner og deres terapeutiske og diagnostiske anvendelse
ITTO940003A0 (it)	1994-01-05	Procedimento per la formazione di conduttori ctc e testa traspositriceper l'attuazione del procedimento.
BR1100532A (pt)	2000-06-06	(+)-alfa-(2,3-dimetoxifenil)-1-[2-(4-fluorfenil)etil]-4-pipe ridinometanol e composição contendo o mesmo
IT1286876B1 (it)	1998-07-17	Procedimento per la preparazione e la conservazione di succo di limone fresco
ITBO980084A0 (it)	1998-02-16	Apparecchiatura per l'esecuzione di trattamenti terapeutici localizzat i, particolarmente ultrasuono terapia e/o vibro terapia.
ITRM980055A0 (it)	1998-01-28	Composizione pr impiego odontoiatrico e procedimento per la sua applicazione
IT1292233B1 (it)	1999-01-29	Dispositivo per il fissaggio di protesi dentarie ed ossee.
LV11523A (lv)	1996-10-20	Domperidona pielietosana kardalgijas arstesana

Legal Events

Date	Code	Title	Description
2013-09-30	MM1K	Lapsed by not paying the annual fees