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PE20150287A1 - Composicion farmaceutica que contiene un acido tetrahidrofolico - Google Patents

Composicion farmaceutica que contiene un acido tetrahidrofolico

Info

Publication number
PE20150287A1
PE20150287A1 PE2014002543A PE2014002543A PE20150287A1 PE 20150287 A1 PE20150287 A1 PE 20150287A1 PE 2014002543 A PE2014002543 A PE 2014002543A PE 2014002543 A PE2014002543 A PE 2014002543A PE 20150287 A1 PE20150287 A1 PE 20150287A1
Authority
PE
Peru
Prior art keywords
pharmaceutical composition
tetrahydropholic
composition containing
progestagen
acid
Prior art date
Application number
PE2014002543A
Other languages
English (en)
Inventor
Kristina King
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36763829&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20150287(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of PE20150287A1 publication Critical patent/PE20150287A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN PROGESTAGENO TAL COMO DROSPIRENONA EN UNA CANTIDAD DE 2.5 A 3.5MG; B) UN ESTROGENO TAL COMO ETINILESTRADIOL EN UNA CANTIDAD DE 0.015 A 0.035MG; C) UNA SAL DE CALCIO DEL ACIDO 5-METIL-(6S)-TETRAHIDROFOLICO EN UNA CANTIDAD DE 0.1 A 5MG; D) CELULOSA MICROCRISTALINA EN UNA CANTIDAD DE 10 A 80MG; Y E) LACTOSA MONOHIDRATO EN UNA CANTIDAD DE 10 A 80MG. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE LA COMPOSICION. DICHA COMPOSICION ES UTIL COMO ANTICONCEPTIVO ORAL Y PROPORCIONAN BUENA ESTABILIDAD DEL ACIDO TETRAHIDROFOLICO DURANTE EL ALMACENAMIENTO ASEGURANDO NO OBSTANTE UNA LIBERACION RAPIDA Y CONFIABLE DEL ESTROGENO Y DEL PROGESTAGENO
PE2014002543A 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un acido tetrahidrofolico PE20150287A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06014002 2006-07-06

Publications (1)

Publication Number Publication Date
PE20150287A1 true PE20150287A1 (es) 2015-03-15

Family

ID=36763829

Family Applications (3)

Application Number Title Priority Date Filing Date
PE2007000867A PE20080273A1 (es) 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un progestageno, un estrogeno y un acido tetrahidrofolico
PE2011002146A PE20120375A1 (es) 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un acido tetrahidrofolico
PE2014002543A PE20150287A1 (es) 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un acido tetrahidrofolico

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PE2007000867A PE20080273A1 (es) 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un progestageno, un estrogeno y un acido tetrahidrofolico
PE2011002146A PE20120375A1 (es) 2006-07-06 2007-07-05 Composicion farmaceutica que contiene un acido tetrahidrofolico

Country Status (31)

Country Link
EP (2) EP2422774B1 (es)
JP (1) JP2009542591A (es)
KR (2) KR20090033889A (es)
CN (3) CN101489563A (es)
AR (2) AR061958A1 (es)
AU (1) AU2007271449B2 (es)
BR (1) BRPI0713565B8 (es)
CA (2) CA2656131C (es)
CL (1) CL2007001962A1 (es)
CO (1) CO6150125A2 (es)
CR (1) CR10549A (es)
CU (1) CU20090004A7 (es)
EC (1) ECSP099030A (es)
ES (1) ES2626838T5 (es)
GT (1) GT200900001A (es)
IL (3) IL196027A0 (es)
MA (1) MA30598B1 (es)
MX (1) MX2009000079A (es)
MY (1) MY169516A (es)
NO (1) NO347567B1 (es)
NZ (1) NZ573766A (es)
PE (3) PE20080273A1 (es)
PH (1) PH12012501774B1 (es)
RU (2) RU2479306C2 (es)
SG (1) SG188869A1 (es)
TN (1) TNSN08543A1 (es)
TW (2) TWI508730B (es)
UA (2) UA105078C2 (es)
UY (1) UY30462A1 (es)
WO (1) WO2008003432A1 (es)
ZA (4) ZA200900868B (es)

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US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
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CN107446458A (zh) * 2017-08-04 2017-12-08 合众(佛山)化工有限公司 一种高耐水性的丙烯酸改性聚氨酯杂化树脂水性涂料
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TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
CN110237046B (zh) * 2019-03-29 2021-07-30 福格森(武汉)生物科技股份有限公司 一种l-5-甲基四氢叶酸微囊的制备方法
CN110548034A (zh) * 2019-07-12 2019-12-10 广州莎蔓生物科技有限公司 一种怀孕阻断药物
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
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Also Published As

Publication number Publication date
NZ573766A (en) 2011-05-27
BRPI0713565B1 (pt) 2021-02-02
CO6150125A2 (es) 2010-04-20
HK1131917A1 (en) 2010-02-12
CU20090004A7 (es) 2011-07-11
WO2008003432A1 (en) 2008-01-10
IL196027A0 (en) 2009-09-01
ZA201501673B (en) 2016-02-24
CU23902B1 (es) 2013-06-28
TW200812593A (en) 2008-03-16
RU2009103649A (ru) 2010-08-20
IL245355B (en) 2019-05-30
CA2656131C (en) 2015-10-13
ES2626838T3 (es) 2017-07-26
MA30598B1 (fr) 2009-07-01
BRPI0713565A2 (pt) 2012-03-20
GT200900001A (es) 2009-12-08
CA2656131A1 (en) 2008-01-10
TNSN08543A1 (en) 2010-04-14
EP2422774A1 (en) 2012-02-29
EP2040683A1 (en) 2009-04-01
AR106561A2 (es) 2018-01-24
KR20130042638A (ko) 2013-04-26
AU2007271449B2 (en) 2013-07-11
CN102813663B (zh) 2019-03-22
CN101484143B (zh) 2012-07-04
PH12012501774A1 (en) 2015-09-21
ZA200900868B (en) 2021-05-26
SG188869A1 (en) 2013-04-30
CA2856344C (en) 2017-02-28
IL245355A0 (en) 2016-06-30
KR20090033889A (ko) 2009-04-06
IL224484A (en) 2016-05-31
TW201538161A (zh) 2015-10-16
CR10549A (es) 2009-01-27
EP2040683B2 (en) 2023-08-16
RU2012133154A (ru) 2014-02-10
NO20090578L (no) 2009-03-09
PH12012501774B1 (en) 2015-09-21
PE20120375A1 (es) 2012-05-23
AR061958A1 (es) 2008-08-10
CN102813663A (zh) 2012-12-12
JP2009542591A (ja) 2009-12-03
PE20080273A1 (es) 2008-05-16
UY30462A1 (es) 2008-02-29
EP2422774B1 (en) 2015-08-12
MY169516A (en) 2019-04-22
CN101489563A (zh) 2009-07-22
ZA201808084B (en) 2021-06-30
UA105078C2 (uk) 2014-04-10
RU2479306C2 (ru) 2013-04-20
ES2626838T5 (es) 2024-03-14
ZA201808083B (en) 2021-06-30
BRPI0713565B8 (pt) 2021-05-25
TWI508730B (zh) 2015-11-21
NO20090578A (no) 2009-03-09
MX2009000079A (es) 2009-01-23
RU2624236C2 (ru) 2017-07-03
CN101484143A (zh) 2009-07-15
NO347567B1 (no) 2024-01-15
AU2007271449A1 (en) 2008-01-10
UA100228C2 (uk) 2012-12-10
EP2040683B1 (en) 2017-03-01
CL2007001962A1 (es) 2008-01-04
CA2856344A1 (en) 2008-01-10
ECSP099030A (es) 2009-02-27

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