PE20110236A1 - Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetina - Google Patents
Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetinaInfo
- Publication number
- PE20110236A1 PE20110236A1 PE2011000084A PE2011000084A PE20110236A1 PE 20110236 A1 PE20110236 A1 PE 20110236A1 PE 2011000084 A PE2011000084 A PE 2011000084A PE 2011000084 A PE2011000084 A PE 2011000084A PE 20110236 A1 PE20110236 A1 PE 20110236A1
- Authority
- PE
- Peru
- Prior art keywords
- lys
- erythropoyetin
- organs
- tissues
- respond
- Prior art date
Links
- 210000000056 organ Anatomy 0.000 title abstract 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical group NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 9
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 9
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- -1 AMINO Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000007912 intraperitoneal administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
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- Immunology (AREA)
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- Addiction (AREA)
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Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE ERITROPOYETINA CARBAMILADA EN LAS POSICIONES DE LISINA: LYS 47, LYS 72, LYS 79, LYS 124, LYS 143, LYS 167, LYS 179 y LYS 181, EN DONDE EL GRUPO AMINO N-TERMINAL DE LA ERITROPOYETINA TAMBIEN ES CARBAMILADO. DICHA COMPOSICION FARMACEUTICA SE PRESENTA COMO UNA FORMULACION PARENTERAL INTRAVENOSA O INTRAPERITONEAL SIENDO UTIL EN LA PROTECCION Y MEJORAMIENTO DE CELULAS, TEJIDOS Y ORGANOS QUE RESPONDEN A LA ERITROPOYETINA
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25924500P | 2000-12-29 | 2000-12-29 | |
| US09/753,132 US6531121B2 (en) | 2000-12-29 | 2000-12-29 | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20110236A1 true PE20110236A1 (es) | 2011-04-11 |
Family
ID=26947185
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001001314A PE20020744A1 (es) | 2000-12-29 | 2001-12-28 | Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetina |
| PE2011000084A PE20110236A1 (es) | 2000-12-29 | 2001-12-28 | Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetina |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001001314A PE20020744A1 (es) | 2000-12-29 | 2001-12-28 | Proteccion y mejoramiento de celulas, tejidos y organos que responden a la eritropoyetina |
Country Status (33)
| Country | Link |
|---|---|
| EP (2) | EP2281828A3 (es) |
| JP (4) | JP2005502584A (es) |
| KR (3) | KR20080041755A (es) |
| CN (2) | CN102319421A (es) |
| AR (1) | AR035412A1 (es) |
| AU (1) | AU2002239665B2 (es) |
| BG (1) | BG108030A (es) |
| BR (1) | BR0116587A (es) |
| CA (1) | CA2432853A1 (es) |
| CL (1) | CL2010000606A1 (es) |
| CZ (1) | CZ20032059A3 (es) |
| DO (1) | DOP2001000321A (es) |
| EA (1) | EA007967B1 (es) |
| EE (1) | EE200300267A (es) |
| ES (1) | ES2564552T3 (es) |
| HR (1) | HRP20030515A2 (es) |
| HU (1) | HUP0302549A3 (es) |
| IL (2) | IL156399A0 (es) |
| IS (1) | IS6843A (es) |
| MX (1) | MXPA03005893A (es) |
| NO (1) | NO332038B1 (es) |
| NZ (2) | NZ551445A (es) |
| PA (1) | PA8536201A1 (es) |
| PE (2) | PE20020744A1 (es) |
| PH (1) | PH12016500941A1 (es) |
| PL (1) | PL365876A1 (es) |
| RS (1) | RS52276B (es) |
| SK (1) | SK9572003A3 (es) |
| SV (1) | SV2003000814A (es) |
| UA (1) | UA91321C2 (es) |
| UY (1) | UY27111A1 (es) |
| WO (1) | WO2002053580A2 (es) |
| ZA (1) | ZA200304551B (es) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
| US7604960B2 (en) | 1999-04-15 | 2009-10-20 | Crucell Holland B.V. | Transient protein expression methods |
| US7297680B2 (en) | 1999-04-15 | 2007-11-20 | Crucell Holland B.V. | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content |
| US8236561B2 (en) | 1999-04-15 | 2012-08-07 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
| US7527961B2 (en) | 1999-11-26 | 2009-05-05 | Crucell Holland B.V. | Production of vaccines |
| US7192759B1 (en) | 1999-11-26 | 2007-03-20 | Crucell Holland B.V. | Production of vaccines |
| US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
| EP1930023A3 (en) * | 2001-04-09 | 2008-08-06 | East Carolina University | Erythropoietin ameliorates chemotherapy-induced toxicity in vivo |
| US7795210B2 (en) | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| EP1465987B1 (en) | 2001-12-07 | 2008-01-23 | Crucell Holland B.V. | Production of viruses, viral isolates and vaccines |
| DE10219545A1 (de) * | 2002-04-26 | 2003-11-06 | Lang Florian | Regulation der Apoptose |
| DE10234192B4 (de) | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| CA2519092C (en) | 2003-03-14 | 2014-08-05 | Neose Technologies, Inc. | Branched water-soluble polymers and their conjugates |
| WO2006127896A2 (en) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Glycopegylated factor ix |
| EP2338333B1 (en) | 2003-04-09 | 2017-09-06 | ratiopharm GmbH | Glycopegylation methods and proteins/peptides produced by the methods |
| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
| US7932364B2 (en) | 2003-05-09 | 2011-04-26 | Novo Nordisk A/S | Compositions and methods for the preparation of human growth hormone glycosylation mutants |
| JP4865539B2 (ja) | 2003-05-09 | 2012-02-01 | クルセル ホランド ベー ヴェー | Ｅ１不死化細胞の培養物及び該培養物を培養して該培養物から得られる産物の収量を増加させる方法 |
| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
| JP2007517769A (ja) * | 2003-09-29 | 2007-07-05 | ウォーレン ファーマシューティカルズ，インコーポレーテッド | 敗血症および癒着形成の治療および予防のための組織保護性サイトカイン |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US7956032B2 (en) | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
| JP5743368B2 (ja) | 2004-01-08 | 2015-07-01 | ラショファーム ゲーエムベーハー | ペプチドのｏ結合型グリコシル化 |
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