UY27111A1 - Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina - Google Patents
Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetinaInfo
- Publication number
- UY27111A1 UY27111A1 UY27111A UY27111A UY27111A1 UY 27111 A1 UY27111 A1 UY 27111A1 UY 27111 A UY27111 A UY 27111A UY 27111 A UY27111 A UY 27111A UY 27111 A1 UY27111 A1 UY 27111A1
- Authority
- UY
- Uruguay
- Prior art keywords
- erythropoietin
- improvement
- protection
- responding
- fabrics
- Prior art date
Links
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 4
- 102000003951 Erythropoietin Human genes 0.000 title abstract 3
- 108090000394 Erythropoietin Proteins 0.000 title abstract 3
- 229940105423 erythropoietin Drugs 0.000 title abstract 3
- 210000000056 organ Anatomy 0.000 title abstract 2
- 239000004744 fabric Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
Abstract
Son provistos métodos y composiciones para la protección o mejoría de una célula, tejido, órgano o parte corporal que responde a la eritropoyetina para su función o viabilidad in vivo, in situ o ex vivo en mamíferos, incluyendo seres humanos, por administración sistémica o local de un modulador de actividad de receptor de eritropotina, tal como una eritropoyetina o una eritropoyetina modificada.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25924500P | 2000-12-29 | 2000-12-29 | |
| US09/753,132 US6531121B2 (en) | 2000-12-29 | 2000-12-29 | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY27111A1 true UY27111A1 (es) | 2002-06-20 |
Family
ID=26947185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY27111A UY27111A1 (es) | 2000-12-29 | 2001-12-31 | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
Country Status (33)
| Country | Link |
|---|---|
| EP (2) | EP2281828A3 (es) |
| JP (4) | JP2005502584A (es) |
| KR (3) | KR20080041755A (es) |
| CN (2) | CN102319421A (es) |
| AR (1) | AR035412A1 (es) |
| AU (1) | AU2002239665B2 (es) |
| BG (1) | BG108030A (es) |
| BR (1) | BR0116587A (es) |
| CA (1) | CA2432853A1 (es) |
| CL (1) | CL2010000606A1 (es) |
| CZ (1) | CZ20032059A3 (es) |
| DO (1) | DOP2001000321A (es) |
| EA (1) | EA007967B1 (es) |
| EE (1) | EE200300267A (es) |
| ES (1) | ES2564552T3 (es) |
| HR (1) | HRP20030515A2 (es) |
| HU (1) | HUP0302549A3 (es) |
| IL (2) | IL156399A0 (es) |
| IS (1) | IS6843A (es) |
| MX (1) | MXPA03005893A (es) |
| NO (1) | NO332038B1 (es) |
| NZ (2) | NZ526722A (es) |
| PA (1) | PA8536201A1 (es) |
| PE (2) | PE20020744A1 (es) |
| PH (1) | PH12016500941A1 (es) |
| PL (1) | PL365876A1 (es) |
| RS (1) | RS52276B (es) |
| SK (1) | SK9572003A3 (es) |
| SV (1) | SV2003000814A (es) |
| UA (1) | UA91321C2 (es) |
| UY (1) | UY27111A1 (es) |
| WO (1) | WO2002053580A2 (es) |
| ZA (1) | ZA200304551B (es) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8236561B2 (en) | 1999-04-15 | 2012-08-07 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
| US7297680B2 (en) | 1999-04-15 | 2007-11-20 | Crucell Holland B.V. | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content |
| US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
| US7604960B2 (en) | 1999-04-15 | 2009-10-20 | Crucell Holland B.V. | Transient protein expression methods |
| US7192759B1 (en) | 1999-11-26 | 2007-03-20 | Crucell Holland B.V. | Production of vaccines |
| US7527961B2 (en) | 1999-11-26 | 2009-05-05 | Crucell Holland B.V. | Production of vaccines |
| US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
| PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| EP1930023A3 (en) * | 2001-04-09 | 2008-08-06 | East Carolina University | Erythropoietin ameliorates chemotherapy-induced toxicity in vivo |
| US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7795210B2 (en) | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| AU2002351444B2 (en) | 2001-12-07 | 2008-02-21 | Crucell Holland B.V. | Production of viruses, viral isolates and vaccines |
| DE10219545A1 (de) * | 2002-04-26 | 2003-11-06 | Lang Florian | Regulation der Apoptose |
| DE10234192B4 (de) | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| US7803777B2 (en) | 2003-03-14 | 2010-09-28 | Biogenerix Ag | Branched water-soluble polymers and their conjugates |
| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
| US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
| ATE414144T1 (de) | 2003-05-09 | 2008-11-15 | Crucell Holland Bv | Kulturen von e1-immortalisierten zellen und verfahren zu deren kultivierung zur erhöhung der produktausbeuten davon |
| WO2004103275A2 (en) | 2003-05-09 | 2004-12-02 | Neose Technologies, Inc. | Compositions and methods for the preparation of human growth hormone glycosylation mutants |
| WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
| MXPA06003234A (es) * | 2003-09-29 | 2006-06-08 | Warren Pharmaceuticals Inc | Citosinas protectoras de los tejidos para el tratamiento y prevencion de la sepsis y la formacion de adhesiones. |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US20060040856A1 (en) | 2003-12-03 | 2006-02-23 | Neose Technologies, Inc. | Glycopegylated factor IX |
| US7956032B2 (en) | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| NZ548123A (en) | 2004-01-08 | 2010-05-28 | Novo Nordisk As | O-linked glycosylation of peptides |
| JP2008505184A (ja) * | 2004-07-02 | 2008-02-21 | ザ ケネス エス．ウォーレン インスティテュート，インコーポレーテッド | 完全にカルバミル化されたエリトロポイエチンを生成する方法 |
| AU2005259689B2 (en) * | 2004-07-07 | 2011-10-06 | H. Lundbeck A/S | Novel carbamylated EPO and method for its production |
| US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
| WO2006031811A2 (en) | 2004-09-10 | 2006-03-23 | Neose Technologies, Inc. | Glycopegylated interferon alpha |
| EP2586456B1 (en) | 2004-10-29 | 2016-01-20 | ratiopharm GmbH | Remodeling and glycopegylation of fibroblast growth factor (FGF) |
| AT500929B1 (de) | 2004-11-09 | 2007-03-15 | Medizinische Uni Wien Muw | Pharmazeutische zubereitung die erythropoietin enthält |
| CN101090973B (zh) * | 2004-12-30 | 2012-03-28 | 克鲁塞尔荷兰公司 | 从表达腺病毒e1a蛋白的细胞中获得唾液酸化增加的重组蛋白质的方法及由此获得的蛋白质 |
| EP2514757A3 (en) | 2005-01-10 | 2014-03-05 | ratiopharm GmbH | Glycopegylated granulocyte colony stimulating factor |
| JP2008527980A (ja) * | 2005-01-25 | 2008-07-31 | アポロ ライフ サイエンシズ リミテッド | 分子およびそのキメラ分子 |
| WO2006121569A2 (en) | 2005-04-08 | 2006-11-16 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
| EP1888098A2 (en) | 2005-05-25 | 2008-02-20 | Neose Technologies, Inc. | Glycopegylated erythropoietin formulations |
| EP1891231A4 (en) | 2005-05-25 | 2011-06-22 | Novo Nordisk As | GLYCOPEGYLATED FACTOR IX |
| PL2540309T3 (pl) | 2005-08-05 | 2018-03-30 | Araim Pharmaceuticals, Inc. | Peptydy chroniące tkanki i ich zastosowanie |
| JPWO2007020922A1 (ja) * | 2005-08-17 | 2009-02-26 | 創 戸苅 | 脳疾患の治療剤および予防剤 |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| AU2007206409A1 (en) | 2006-01-18 | 2007-07-26 | Chugai Seiyaku Kabushiki Kaisha | Method of removing sialic acid and process for producing asialoerythropoietin |
| WO2008011633A2 (en) | 2006-07-21 | 2008-01-24 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
| US20100075375A1 (en) | 2006-10-03 | 2010-03-25 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates |
| AR065613A1 (es) * | 2007-03-09 | 2009-06-17 | Chugai Pharmaceutical Co Ltd | Agentes de proteccion para organos transplantados |
| PL2144923T3 (pl) | 2007-04-03 | 2013-12-31 | Biogenerix Ag | Sposoby leczenia z użyciem glikopegilowanego G-CSF |
| MX2009013259A (es) | 2007-06-12 | 2010-01-25 | Novo Nordisk As | Proceso mejorado para la produccion de azucares de nucleotidos. |
| US8207112B2 (en) | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
| SG10202011946PA (en) | 2008-01-22 | 2020-12-30 | Araim Pharmaceuticals Inc | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage |
| WO2009102021A1 (ja) * | 2008-02-14 | 2009-08-20 | Kyoto University | 骨髄由来幹細胞、前駆細胞機能賦活による網膜疾患治療 |
| RU2573587C2 (ru) | 2008-02-27 | 2016-01-20 | Ново Нордиск А/С | Конъюгированные молекулы фактора viii |
| CN102186879A (zh) * | 2008-05-29 | 2011-09-14 | 韩诺生物制约株式会社 | 修饰的显示增加的蛋白酶抗性的促红细胞生成素(epo)多肽及其药物组合物 |
| HUE035168T2 (en) | 2008-09-26 | 2018-05-02 | Ambrx Inc | Modified animal erythropoietin polypeptides and their applications |
| EP2590666B1 (en) | 2010-07-06 | 2017-04-26 | Augustinus Bader | Topical application of erythropoietin for use in the treatment of injuries of the cornea |
| WO2013180809A1 (en) | 2012-05-29 | 2013-12-05 | North Carolina Central University | Methods for the production of cytoprotective asialo-erythropoietin in plants and its purification from plant tissues |
| JP2019523633A (ja) | 2016-04-29 | 2019-08-29 | アライム ファーマシューティカルズ，インコーポレーテッド | 組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド |
| CN109415426B (zh) * | 2016-07-12 | 2022-03-11 | 赫克萨尔股份公司 | 具有降低的唾液酸残基的乙酰化率的糖蛋白 |
| RU2709833C1 (ru) * | 2019-06-13 | 2019-12-23 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции микроциркуляции в плаценте асиалированным эритропоэтином при ADMA-подобной модели преэклампсии |
| RU2707060C1 (ru) * | 2019-06-14 | 2019-11-21 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции эндотелиальной дисфункции асиалированным эритропоэтином при ADMA-подобной модели преэклампсии |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215051A (en) | 1979-08-29 | 1980-07-29 | Standard Oil Company (Indiana) | Formation, purification and recovery of phthalic anhydride |
| KR850004274A (ko) * | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
| US4703008A (en) | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
| US4704355A (en) | 1985-03-27 | 1987-11-03 | New Horizons Diagnostics Corporation | Assay utilizing ATP encapsulated within liposome particles |
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US4835260A (en) | 1987-03-20 | 1989-05-30 | Genetics Institute, Inc. | Erythropoietin composition |
| JPH029900A (ja) * | 1988-04-12 | 1990-01-12 | Kirin Amgen Inc | 修飾エリスロポエチン |
| US5308617A (en) * | 1988-08-10 | 1994-05-03 | Halzyme Ltd. | Protein heparin conjugates |
| FR2646438B1 (fr) | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| DE3923963A1 (de) | 1989-07-20 | 1991-01-31 | Behringwerke Ag | Muteine des menschlichen erythropoetins, ihre herstellung und ihre verwendung |
| WO1991004014A1 (en) | 1989-09-21 | 1991-04-04 | Synergen, Inc. | Method for transporting compositions across the blood brain barrier |
| US5856298A (en) | 1989-10-13 | 1999-01-05 | Amgen Inc. | Erythropoietin isoforms |
| KR100263845B1 (ko) * | 1989-10-13 | 2000-08-16 | 스튜어트 엘.왓트 | 에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물 |
| WO1991006667A1 (en) | 1989-11-06 | 1991-05-16 | Cell Genesys, Inc. | Production of proteins using homologous recombination |
| JP3156236B2 (ja) * | 1991-09-30 | 2001-04-16 | 雪印乳業株式会社 | 記憶障害改善治療剤 |
| PT101031B (pt) | 1991-11-05 | 2002-07-31 | Transkaryotic Therapies Inc | Processo para o fornecimento de proteinas por terapia genetica |
| US5625035A (en) * | 1992-06-05 | 1997-04-29 | The Regents, University Of California | Erythropoietin binding protein from mammalian serum |
| US6153407A (en) * | 1992-07-28 | 2000-11-28 | Beth Israel Deaconess Medical Center | Erythropoietin DNA having modified 5' and 3' sequences and its use to prepare EPO therapeutics |
| WO1994026087A2 (en) | 1993-05-14 | 1994-11-24 | Connor Kim C O | Recombinant protein production and insect cell culture and process |
| IL110669A (en) | 1993-08-17 | 2008-11-26 | Kirin Amgen Inc | Erythropoietin analogs |
| US5830851A (en) | 1993-11-19 | 1998-11-03 | Affymax Technologies N.V. | Methods of administering peptides that bind to the erythropoietin receptor |
| US5773569A (en) | 1993-11-19 | 1998-06-30 | Affymax Technologies N.V. | Compounds and peptides that bind to the erythropoietin receptor |
| US5767078A (en) | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
| JP3343357B2 (ja) | 1995-11-13 | 2002-11-11 | 寳酒造株式会社 | レトロウイルスによる標的細胞への遺伝子導入方法 |
| US5856292A (en) | 1996-04-08 | 1999-01-05 | Colgate Palmolive Company | Light duty liquid cleaning compositions |
| US5835382A (en) | 1996-04-26 | 1998-11-10 | The Scripps Research Institute | Small molecule mimetics of erythropoietin |
| BR9712675A (pt) | 1996-10-25 | 1999-10-19 | Searle & Co | Agonistas do receptor de eritropoietina circularmente permutados. |
| WO2000042175A1 (en) * | 1999-01-14 | 2000-07-20 | Bolder Biotechnology Inc. | Methods for making proteins containing free cysteine residues |
| DE19857609A1 (de) * | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
| TR200103785T2 (tr) * | 1999-04-13 | 2002-06-21 | The Kenneth S. Warren Institute, Inc. | Uyarılabilir doku işlevinin periferik olarak uygulanan eritropoietin vasıtasıyla düzenlenmesi |
| PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
| US9209627B2 (en) | 2010-08-25 | 2015-12-08 | Access Business Group International Llc | Wireless power supply system and multi-layer shim assembly |
| KR101290029B1 (ko) | 2011-01-20 | 2013-07-30 | 에스티팜 주식회사 | 시타글립틴의 중간체 제조방법 |
-
2001
- 2001-12-27 PA PA20018536201A patent/PA8536201A1/es unknown
- 2001-12-28 CN CN2011102274750A patent/CN102319421A/zh active Pending
- 2001-12-28 EE EEP200300267A patent/EE200300267A/xx unknown
- 2001-12-28 AU AU2002239665A patent/AU2002239665B2/en not_active Ceased
- 2001-12-28 IL IL15639901A patent/IL156399A0/xx active IP Right Grant
- 2001-12-28 PL PL01365876A patent/PL365876A1/xx not_active Application Discontinuation
- 2001-12-28 NZ NZ526722A patent/NZ526722A/en not_active IP Right Cessation
- 2001-12-28 EP EP10012572A patent/EP2281828A3/en not_active Withdrawn
- 2001-12-28 CN CNA018229492A patent/CN1505638A/zh active Pending
- 2001-12-28 KR KR1020087010285A patent/KR20080041755A/ko not_active Ceased
- 2001-12-28 RS YU53103A patent/RS52276B/sr unknown
- 2001-12-28 WO PCT/US2001/049479 patent/WO2002053580A2/en not_active Ceased
- 2001-12-28 MX MXPA03005893A patent/MXPA03005893A/es active IP Right Grant
- 2001-12-28 SK SK957-2003A patent/SK9572003A3/sk unknown
- 2001-12-28 HU HU0302549A patent/HUP0302549A3/hu not_active Application Discontinuation
- 2001-12-28 UA UA2003077040A patent/UA91321C2/uk unknown
- 2001-12-28 KR KR1020037008843A patent/KR100880201B1/ko not_active Expired - Fee Related
- 2001-12-28 EP EP01987457.7A patent/EP1406922B1/en not_active Expired - Lifetime
- 2001-12-28 KR KR1020097013419A patent/KR100985615B1/ko not_active Expired - Fee Related
- 2001-12-28 EA EA200300738A patent/EA007967B1/ru not_active IP Right Cessation
- 2001-12-28 JP JP2002555103A patent/JP2005502584A/ja active Pending
- 2001-12-28 NZ NZ551445A patent/NZ551445A/en unknown
- 2001-12-28 PE PE2001001314A patent/PE20020744A1/es not_active Application Discontinuation
- 2001-12-28 CA CA002432853A patent/CA2432853A1/en not_active Abandoned
- 2001-12-28 ES ES01987457.7T patent/ES2564552T3/es not_active Expired - Lifetime
- 2001-12-28 CZ CZ20032059A patent/CZ20032059A3/cs unknown
- 2001-12-28 PE PE2011000084A patent/PE20110236A1/es not_active Application Discontinuation
- 2001-12-28 DO DO2001P000321A patent/DOP2001000321A/es unknown
- 2001-12-28 HR HR20030515A patent/HRP20030515A2/hr not_active Application Discontinuation
- 2001-12-28 BR BR0116587-9A patent/BR0116587A/pt not_active Application Discontinuation
- 2001-12-31 UY UY27111A patent/UY27111A1/es unknown
-
2002
- 2002-01-02 AR ARP020100003A patent/AR035412A1/es unknown
- 2002-01-03 SV SV2002000814A patent/SV2003000814A/es not_active Application Discontinuation
-
2003
- 2003-06-11 ZA ZA2003/04551A patent/ZA200304551B/en unknown
- 2003-06-11 IL IL156399A patent/IL156399A/en not_active IP Right Cessation
- 2003-06-13 IS IS6843A patent/IS6843A/is unknown
- 2003-06-24 NO NO20032912A patent/NO332038B1/no not_active IP Right Cessation
- 2003-07-25 BG BG108030A patent/BG108030A/bg unknown
-
2009
- 2009-09-10 JP JP2009209009A patent/JP2010031017A/ja active Pending
-
2010
- 2010-06-09 CL CL2010000606A patent/CL2010000606A1/es unknown
-
2013
- 2013-04-25 JP JP2013092598A patent/JP6114099B2/ja not_active Expired - Fee Related
-
2015
- 2015-07-15 JP JP2015141106A patent/JP2015221816A/ja active Pending
-
2016
- 2016-05-20 PH PH12016500941A patent/PH12016500941A1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY27111A1 (es) | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina | |
| AR040396A1 (es) | Citoquinas protectoras de tejidos para la proteccion, restauracion y mejoramiento de celulas, tejidos y organos receptivos | |
| NO20050504L (no) | Rekombinante vevsbeskyttende cytokiner og nukleinsyrer som koder for slike, for beskyttelse, gjenoppbygging og oking av responsive celler, vev og organer | |
| TW200509983A (en) | The dermal external agent for inhibiting or repairing the dermal damage due to drying | |
| MXPA96004911A (es) | Pellas de matriz de liberacion lenta y su produccion. | |
| ES2138271T3 (es) | Compuestos de 6-dimetil-amino-metil-1-fenil-ciclohexano como principio activo farmaceutico. | |
| MX390753B (es) | Metodos para reprogramar celulas y usos de los mismos. | |
| CR9351A (es) | Composiciones y metodos para aplicaicon topica y suministro transdermico de toxina botulinica | |
| ES2175460T3 (es) | Compuesto de lipoxinas y su utilizacion en el tratamiento de patologias con proliferacion celular. | |
| CY1108798T1 (el) | To μονοξειδιο toy ανθρακα βελτιωνει τα αποτελεσματα στις μεταμοσχευσεις ιστου και οργανων και καταστελει την αποπτωση | |
| ATE279910T1 (de) | Tensid für äusserlich anzuwendende hautpräparate und diese beinhaltende äusserlich anzuwendende hautpräparate | |
| ES2105913T3 (es) | Composiciones para el teñido de las fibras queratinicas que comprenden un orto-diamino pirazol y una sal de manganeso, procedimiento de teñido que utiliza estas composiciones. | |
| CL2004000931A1 (es) | Pelicula consumible adaptada para adherirse y disolverse en la cavidad bucal que comprende un almidon modificado y un agente farmaceuticamente activo. | |
| ATE370730T1 (de) | Pharmazeutische zubereitungen, die chelatbildner/sequestriermittel enthalten und deren dermatologische verwendung | |
| DE50107916D1 (de) | Dreidimensionales hautmodell | |
| CY1107454T1 (el) | Μητρα αμεσης συμπιεσης για ελεγχομενη απελευθερωση ημepησιων μονοδοσεων της κλαριθρομυκινης | |
| CR10289A (es) | "estratrienos 9-alfa-sustituidos como estrogenos de eficacia selectiva"(divisional) | |
| CU23797A3 (es) | Método para preparar tejido orgánico acelular para revitalización | |
| TR200201071T2 (tr) | Rar selektif retinoid antagonistleri kullanılarak anfizem tedavisi | |
| DE50101479D1 (de) | Fluoresceinisothiocyanat-(fitc)-sinistrin, seine herstellung und verwendung | |
| BR0311479A (pt) | Derivados de tiofeno antelmìnticos e inseticidas | |
| CR6452A (es) | Composicion de resorcinol | |
| HN2000000090A (es) | Sal difosfato de un derivado de 4sustituido-9-desoxo-9a-aza-9a-homoeritromicina y su composicion farmaceutica. | |
| CR11211A (es) | Estratienos 8-beta-sustituidos como estrogenos de accion selectiva | |
| ECSP088994A (es) | INHIBIDORES DE CANAL DE POTASIO Kv1.5 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DESI | Application deemed to be withdrawn |
Effective date: 20140325 |