PE20020355A1 - Genes involucrados en la produccion de un compuesto isoprenoide - Google Patents
Genes involucrados en la produccion de un compuesto isoprenoideInfo
- Publication number
- PE20020355A1 PE20020355A1 PE2001000878A PE2001000878A PE20020355A1 PE 20020355 A1 PE20020355 A1 PE 20020355A1 PE 2001000878 A PE2001000878 A PE 2001000878A PE 2001000878 A PE2001000878 A PE 2001000878A PE 20020355 A1 PE20020355 A1 PE 20020355A1
- Authority
- PE
- Peru
- Prior art keywords
- nucleic acid
- isolated
- production
- utilized
- refers
- Prior art date
Links
- -1 ISOPRENOID COMPOUND Chemical class 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 7
- 102000039446 nucleic acids Human genes 0.000 abstract 7
- 150000007523 nucleic acids Chemical class 0.000 abstract 7
- 229920001621 AMOLED Polymers 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 241000589344 Methylomonas Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 150000003505 terpenes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE REFIERE A FRAGMENTOS DE ACIDO NUCLEICO QUE CODIFICAN ENZIMAS UTILES PARA LA PRODUCCION DE COMPUESTOS ISOPRENOIDES O UNA MOLECULA DE ACIDO NUCLEICO AISLADA QUE CODIFICA UNA ENZIMA BIOSINTETICA ISOPRENOIDE SELECCIONADA DE: a) UNA MOLECULA AISLADA DE ACIDO NUCLEICO QUE CODIFICA LA SECUENCIA DE AMINACIDOS SEC ID No 2, 4, 6, 8, 10, 12, 14, 16, 18 Y 24; b) UNA MOLECULA AISLADA DE ACIDO NUCLEICO QUE SE HIBRIDIZA CON 0,1% SDS, 0,1% SDS, 65°C Y LAVADA CON 2X SSC Y c) MOLECULA AISLADA DE ACIDO NUCLEICO QUE CODIFICA LA SECUENCIA No 1, 3, 5, 7, 9, ENTRE OTRAS. SE REFIERE TAMBIEN A UNA MOLECULA AISLADA DE ACIDO NUCLEICO DE UNA PRIMERA SECUENCIA NUCLEOTIDA QUE CODIFICA UN POLIPEPTIDO DE POR LO MENOS 620 AMINOACIDOS QUE TIENEN POR LO MENOS 60% DE IDENTIDAD CUANDO SE COMPARA A UN POLIPEPTIDO DE LA SEC ID No :2. SE REFIERE TAMBIEN A UN METODO DONDE LA BACTERIA METANOTROFIA SE DESARROLLA EN UN SUBSTRATO DE CARBONO SELECCIONADO DE METANO Y ETANOL DONDE DICHA BACTERIA ES METHYLOMONAS 16a ATCC PTA 2402. LOS GENES Y PRODUCTOS DE GENES SON AISLADOS DESDE UNA CEPA METHYLOMONAS QUE ES CAPAZ DE UTILIZAR SUBTRATOS DE CARBONO SIMPLE COMO FUENTES DE ENERGIA Y PUEDEN USARSE PARA LA PRODUCCION DE COMPUESTOS ISOPRENOIDES EN UNA VARIEDAD DE ORGANISMOS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22990700P | 2000-09-01 | 2000-09-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020355A1 true PE20020355A1 (es) | 2002-06-19 |
Family
ID=22863158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000878A PE20020355A1 (es) | 2000-09-01 | 2001-09-03 | Genes involucrados en la produccion de un compuesto isoprenoide |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6660507B2 (es) |
| EP (1) | EP1360301A2 (es) |
| JP (1) | JP2005500804A (es) |
| AU (1) | AU2001288476A1 (es) |
| CA (1) | CA2416940A1 (es) |
| NO (1) | NO20030830L (es) |
| PE (1) | PE20020355A1 (es) |
| WO (1) | WO2002020733A2 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001287273A1 (en) * | 2000-03-24 | 2001-10-08 | Maxygen, Inc. | Methods for modulating cellular and organismal phenotypes |
| US6818424B2 (en) | 2000-09-01 | 2004-11-16 | E. I. Du Pont De Nemours And Company | Production of cyclic terpenoids |
| US7026464B2 (en) | 2002-10-21 | 2006-04-11 | E. I. Du Pont De Nemours And Company | Natural promoters for gene expression in C1 metabolizing bacteria |
| US20040219629A1 (en) * | 2002-12-19 | 2004-11-04 | Qiong Cheng | Increasing carotenoid production in bacteria via chromosomal integration |
| US7070952B2 (en) * | 2003-05-07 | 2006-07-04 | E. I. Du Pont Nemours And Company | Genes encoding carotenoid compounds |
| US7232666B2 (en) * | 2003-12-03 | 2007-06-19 | E. I. Du Pont De Nemours And Company | Optimized bacterial host strains of Methylomonas sp. 16a |
| US20050287625A1 (en) * | 2004-03-05 | 2005-12-29 | Miller Edward S Jr | Process for expression of foreign genes in methylotrophic bacteria through chromosomal integration |
| US20060045871A1 (en) * | 2004-09-02 | 2006-03-02 | Odom James M | Antioxidant activity from methanotrophic biomass |
| WO2006102342A2 (en) | 2005-03-18 | 2006-09-28 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| US20070065902A1 (en) * | 2005-09-19 | 2007-03-22 | Dicosimo Deana J | Process for chromosomal expression of foreign genes in the fliC region of a methylotrophic microbial host cell |
| US20070065900A1 (en) * | 2005-09-19 | 2007-03-22 | Dicosimo Deana J | Process for chromosomal expression of foreign genes in the cytochrome-C peroxidase (cytCP) region of a methylotrophic microbial host cell |
| US8273558B2 (en) | 2005-10-26 | 2012-09-25 | Butamax(Tm) Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| CN101297042A (zh) * | 2005-10-26 | 2008-10-29 | 纳幕尔杜邦公司 | 四碳醇的发酵生产 |
| EP2078092A2 (en) | 2006-09-28 | 2009-07-15 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| CN101636474B (zh) * | 2006-11-21 | 2016-01-20 | 阿迈瑞斯公司 | 喷气燃料组合物及其制备和使用方法 |
| CA2670307C (en) * | 2006-11-21 | 2013-06-25 | Amyris Biotechnologies, Inc. | Jet fuel compositions and methods of making and using same |
| BRPI0718973A2 (pt) * | 2006-11-21 | 2014-02-04 | Amyris Biotechnologies Inc | Composição de combustível, métodos para preparar uma composição de combustível, e para acionar um motor, e, veículo |
| WO2009005704A1 (en) * | 2007-07-03 | 2009-01-08 | The Regents Of The University Of California | Methods of increasing isoprenoid or isoprenoid precursor production |
| CN101952448A (zh) * | 2007-12-23 | 2011-01-19 | 格沃股份有限公司 | 高产率产生异丁醇的酵母生物 |
| US8455239B2 (en) | 2007-12-23 | 2013-06-04 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
| BRPI0909989A2 (pt) | 2008-06-05 | 2021-06-22 | Butamax Advanced Biofuels Llc | célula de levedura recombinante e método para a produção de um produto |
| NZ604915A (en) | 2010-06-02 | 2014-10-31 | Evolva Nutrition Inc | Recombinant production of steviol glycosides |
| CN103732753B (zh) | 2011-08-08 | 2018-03-30 | 埃沃尔瓦公司 | 甜菊醇糖苷类的重组生产 |
| JP2014076042A (ja) | 2012-09-21 | 2014-05-01 | Sekisui Chem Co Ltd | 組換え細胞、並びに、β−フェランドレンの生産方法 |
| EP3892728A1 (en) | 2013-02-06 | 2021-10-13 | Evolva SA | Methods for improved production of rebaudioside d and rebaudioside m |
| SG10201705993YA (en) | 2013-02-11 | 2017-08-30 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| US9267158B2 (en) | 2013-03-14 | 2016-02-23 | Intrexon Corporation | Biological production of multi-carbon compounds from methane |
| MX2017001859A (es) | 2014-08-11 | 2017-04-11 | Evolva Sa | Produccion de glicosidos de esteviol en hospederos recombinantes. |
| KR20170052647A (ko) | 2014-09-09 | 2017-05-12 | 에볼바 에스아 | 재조합 숙주에서 스테비올 글리코시드의 생성 |
| JP2018503388A (ja) | 2015-01-30 | 2018-02-08 | エヴォルヴァ エスアー.Evolva Sa. | 組み換え宿主におけるステビオールグリコシドの生産 |
| US10604743B2 (en) | 2015-03-16 | 2020-03-31 | Dsm Ip Assets B.V. | UDP-glycosyltransferases |
| CA2995067A1 (en) | 2015-08-07 | 2017-02-16 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CA3020671A1 (en) | 2016-04-13 | 2017-10-19 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| WO2017198682A1 (en) | 2016-05-16 | 2017-11-23 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN109312281A (zh) | 2016-06-17 | 2019-02-05 | 凯利斯塔公司 | 进气发酵反应器、系统和方法 |
| WO2018083338A1 (en) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| RU2761409C2 (ru) | 2017-01-10 | 2021-12-08 | Калиста, Инк. | Реакторы, системы и способы ферментации с подачей газа с применением зоны вертикального потока |
| AU2018318073B2 (en) | 2017-08-14 | 2024-05-09 | Calysta, Inc. | Gas-fed fermentation reactors, systems and processes utilizing gas/liquid separation vessels |
| US20230082497A1 (en) * | 2020-02-20 | 2023-03-16 | Yield10 Bioscience, Inc. | Genetically engineered plants that express 6-phosphogluconate dehydratase and/or 2-keto-3-deoxy-6-phosphogluconate aldolase |
| EP4453246A4 (en) * | 2021-12-20 | 2025-12-24 | Countable Labs Inc | DIGITAL DETECTION AND QUANTIFICATION OF MULTIPLE TARGETS |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5429939A (en) | 1989-04-21 | 1995-07-04 | Kirin Beer Kabushiki Kaisha | DNA sequences useful for the synthesis of carotenoids |
| US5530189A (en) | 1990-03-02 | 1996-06-25 | Amoco Corporation | Lycopene biosynthesis in genetically engineered hosts |
| RU2149823C1 (ru) | 1994-01-20 | 2000-05-27 | Уилльям Левин Лимитед | Устройство для открывания консервных банок |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| ATE262590T1 (de) | 1995-06-09 | 2004-04-15 | Dsm Ip Assets Bv | Fermentative herstellung von carotenoiden |
| ATE275632T1 (de) | 1995-12-22 | 2004-09-15 | Dsm Ip Assets Bv | Verbesserte verfahren zur transformation von phaffiastämmen,transformierte phaffiastämme auf diese weise erhaltend, und rekominante dns in besagtem verfahren verwendbar |
| JP3209103B2 (ja) | 1996-07-03 | 2001-09-17 | トヨタ自動車株式会社 | 変異型プレニル二燐酸合成酵素 |
| ES2200110T3 (es) | 1996-12-02 | 2004-03-01 | F. Hoffmann-La Roche Ag | Produccion fermentativa de caroteniodes mejorada. |
| WO1999011757A1 (en) | 1997-09-02 | 1999-03-11 | Washington State University Research Foundation | NUCLEIC AND AMINO ACID SEQUENCES FOR A NOVEL TRANSKETOLASE FROM $i (MENTHA PIPERITA) |
| JP3562280B2 (ja) | 1997-12-16 | 2004-09-08 | トヨタ自動車株式会社 | ゲラニル二リン酸合成酵素遺伝子 |
| US6806076B1 (en) | 1998-04-14 | 2004-10-19 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity |
| EP0955363A3 (en) | 1998-05-06 | 2004-01-28 | F. Hoffmann-La Roche Ag | Dna sequences encoding enzymes involved in production of isoprenoids |
| AU3964599A (en) | 1998-05-13 | 1999-11-29 | University Of Maryland | Methods of modifying the production of isopentenyl pyrophosphate, dimethylallyl pyrophosphate and/or isoprenoids |
| AU2163300A (en) | 1998-12-04 | 2000-06-26 | E.I. Du Pont De Nemours And Company | Plant 1-deoxy-d-xylulose 5-phosphate reductoisomerase |
| GB9901902D0 (en) | 1999-01-28 | 1999-03-17 | New Royal Holloway & Bedford | Manipulating isoprenoid expression |
| US6281017B1 (en) | 1999-02-03 | 2001-08-28 | Washington State University Research Foundation | 1-deoxy-d-xylulose-5-phosphate reductoisomerases and method of use |
| US6107058A (en) | 1999-03-26 | 2000-08-22 | Smithkline Beecham Corporation | ispA from Staphylococcus aureus |
| EP1043403A1 (en) | 1999-04-09 | 2000-10-11 | GPC AG, Genome Pharmaceuticals Corporation | Novel method for identifying antibacterial compounds |
| CA2365929A1 (en) | 1999-04-09 | 2000-10-19 | Gpc Biotech Ag | Novel method for identifying antibacterial compounds |
| DE19916176A1 (de) | 1999-04-10 | 2000-10-12 | Bayer Ag | Neue essentielle bakterielle Gene und ihre Proteine |
| EP1190068B1 (en) | 1999-04-15 | 2006-01-25 | Calgene LLC | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| DE19918949A1 (de) | 1999-04-27 | 2000-11-23 | Basf Ag | Überexpression einer DNA-Sequenz codierend für eine 1-Desoxy-D-Xylulose-5-Phosphat Reduktoisomerase in Pflanzen |
| EP1063297B1 (en) | 1999-06-22 | 2008-12-17 | Korea Kumho Petrochemical Co. Ltd. | Farnesyl pyrophosphate synthase (FPS) derived from seedlings of sunflower (Helianthus annus) |
| EP1198575B1 (en) | 1999-08-04 | 2007-09-19 | Adelbert Bacher | Isoprenoid biosynthesis |
| AU2001269685A1 (en) | 2000-05-03 | 2001-11-12 | The Salk Institute For Biological Studies | Crystallization of 4-diphosphocytidyl-2-c-methylerythritol synthesis |
| DE10021688A1 (de) | 2000-05-05 | 2001-11-15 | Hassan Jomaa | Gene des 1-Desoxy-D-xylulose-Biosynthesewegs |
| DE10027821A1 (de) | 2000-06-05 | 2001-12-06 | Adelbert Bacher | Der Mevalonat-unabhängige Isoprenoidbiosyntheseweg |
-
2001
- 2001-08-22 US US09/934,903 patent/US6660507B2/en not_active Expired - Fee Related
- 2001-08-29 JP JP2002525740A patent/JP2005500804A/ja active Pending
- 2001-08-29 EP EP01968214A patent/EP1360301A2/en not_active Withdrawn
- 2001-08-29 CA CA002416940A patent/CA2416940A1/en not_active Abandoned
- 2001-08-29 AU AU2001288476A patent/AU2001288476A1/en not_active Abandoned
- 2001-08-29 WO PCT/US2001/026852 patent/WO2002020733A2/en not_active Ceased
- 2001-09-03 PE PE2001000878A patent/PE20020355A1/es not_active Application Discontinuation
-
2003
- 2003-02-21 NO NO20030830A patent/NO20030830L/no not_active Application Discontinuation
- 2003-11-03 US US10/700,003 patent/US7056717B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040063143A1 (en) | 2004-04-01 |
| US20020102690A1 (en) | 2002-08-01 |
| EP1360301A2 (en) | 2003-11-12 |
| NO20030830L (no) | 2003-04-30 |
| US6660507B2 (en) | 2003-12-09 |
| JP2005500804A (ja) | 2005-01-13 |
| CA2416940A1 (en) | 2002-03-14 |
| WO2002020733A3 (en) | 2003-08-14 |
| AU2001288476A1 (en) | 2002-03-22 |
| NO20030830D0 (no) | 2003-02-21 |
| WO2002020733A2 (en) | 2002-03-14 |
| US7056717B2 (en) | 2006-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |