PE20000120A1 - Composicion de metilfenidato en forma solida para uso topico - Google Patents
Composicion de metilfenidato en forma solida para uso topicoInfo
- Publication number
- PE20000120A1 PE20000120A1 PE1998001219A PE00121998A PE20000120A1 PE 20000120 A1 PE20000120 A1 PE 20000120A1 PE 1998001219 A PE1998001219 A PE 1998001219A PE 00121998 A PE00121998 A PE 00121998A PE 20000120 A1 PE20000120 A1 PE 20000120A1
- Authority
- PE
- Peru
- Prior art keywords
- methylphenidate
- composition
- copolymers
- presented
- refers
- Prior art date
Links
- DUGOZIWVEXMGBE-UHFFFAOYSA-N Methylphenidate Chemical group C=1C=CC=CC=1C(C(=O)OC)C1CCCCN1 DUGOZIWVEXMGBE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960001344 methylphenidate Drugs 0.000 title abstract 4
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title 1
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 244000043261 Hevea brasiliensis Species 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 229920003052 natural elastomer Polymers 0.000 abstract 1
- 229920001194 natural rubber Polymers 0.000 abstract 1
- 229920000058 polyacrylate Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 229920003051 synthetic elastomer Polymers 0.000 abstract 1
- 239000005061 synthetic rubber Substances 0.000 abstract 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
SE REFIERE A UNA COMPOSICION PARA LA APLICACION TOPICA DE METILFENIDATO PRESENTADO EN UN SISTEMA LIMITADO Y FLEXIBLE PARA LA ADMINISTRACION EN LA PIEL O EN LAS MUCOSAS POR 10 HORAS Y EN CANTIDAD SUFICIENTE PARA LOGRAR UNA CINETICA DE ORDEN CERO; EL METILFENIDATO SE PRESENTA COMO BASE, SAL BASICA, ESTER, ENANTIOMERO d-TREO-METILFENIDIATO. LA COMPOSICION COMPRENDE ADEMAS UN MATERIAL ADHESIVO SIENDO DE PREFERENCIA ACRILICOS; CAUCHOS NATURALES; CAUCHOS SINTETICOS; ADHESIVOS BIOLOGICOS TAL COMO POLISACARIDOS NATURALES O SINTETICOS; POLISILOXANOS; POLIACRILATOS, POLIVINIL PIRROLIDONAS, COPOLIMEROS DE VINILPIRROLIDONA; COPOLIMEROS DE BLOQUES DE ESTIRENO. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. EL METILFENIDATO ES UN ESTIMULANTE DEL SISTEMA NERVIOSO CENTRAL POR LO QUE LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO DE TRASTORNO DE DEFICIT DE LA ATENCION Y DEFICIT DE LA ATENCION CON HIPERACTIVIDAD
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6951097P | 1997-12-15 | 1997-12-15 | |
| US09/163,351 US6210705B1 (en) | 1997-12-15 | 1998-09-30 | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000120A1 true PE20000120A1 (es) | 2000-02-19 |
Family
ID=26750154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998001219A PE20000120A1 (es) | 1997-12-15 | 1998-12-15 | Composicion de metilfenidato en forma solida para uso topico |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US6210705B1 (es) |
| EP (2) | EP2314288B1 (es) |
| JP (3) | JP4316800B2 (es) |
| KR (1) | KR100633348B1 (es) |
| CN (1) | CN1368876A (es) |
| AR (1) | AR014062A1 (es) |
| AT (1) | ATE260652T1 (es) |
| AU (1) | AU752027B2 (es) |
| BR (1) | BR9814282A (es) |
| CA (1) | CA2315237C (es) |
| CZ (2) | CZ300535B6 (es) |
| DE (1) | DE69822199T2 (es) |
| DK (1) | DK1037615T3 (es) |
| ES (2) | ES2219926T3 (es) |
| HK (1) | HK1049447A1 (es) |
| HU (1) | HU226615B1 (es) |
| IL (1) | IL136760A0 (es) |
| LV (1) | LV12558B (es) |
| NO (1) | NO329974B1 (es) |
| NZ (1) | NZ505689A (es) |
| PE (1) | PE20000120A1 (es) |
| PL (1) | PL195315B1 (es) |
| PT (1) | PT1037615E (es) |
| RU (1) | RU2233156C2 (es) |
| SI (1) | SI20360B (es) |
| TR (1) | TR200001736T2 (es) |
| TW (2) | TWI242452B (es) |
| WO (1) | WO1999030694A2 (es) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US20020102291A1 (en) * | 1997-12-15 | 2002-08-01 | Noven Pharmaceuticals, Inc. | Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
| GB9913458D0 (en) * | 1999-06-09 | 1999-08-11 | Medeva Europ Ltd | The therapeutic use of d-threo-methylphenidate |
| GB9918735D0 (en) * | 1999-08-09 | 1999-10-13 | Straken Limited | Transdermal patches |
| CO5261532A1 (es) * | 1999-11-15 | 2003-03-31 | Novartis Ag | Compuestos heterociclicos sililados, procedimiento para la preparacion de estos y composicion farmaceutica que los contiene |
| ES2210025T3 (es) * | 1999-12-17 | 2004-07-01 | Celltech Pharma Europe Limited | Agente farmaceutico para el tratamiento de estados convulsivos. |
| US6455066B1 (en) | 2000-03-10 | 2002-09-24 | Epicept Corporation | Intradermal-penetration agents for topical local anesthetic administration |
| US6905016B2 (en) * | 2000-03-14 | 2005-06-14 | Noven Pharmaceuticals, Inc. | Packaging system for transdermal drug delivery systems |
| US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
| US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
| DE10060550C1 (de) * | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten |
| EP1366762B1 (en) * | 2001-03-07 | 2015-12-30 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
| FR2822049B1 (fr) * | 2001-03-13 | 2003-08-01 | Dbv Medica 1 | Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation |
| US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
| NZ528148A (en) * | 2001-03-16 | 2006-02-24 | Alza Corp | Transdermal patch for administering fentanyl |
| DE10141650C1 (de) * | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| US20030049272A1 (en) * | 2001-08-30 | 2003-03-13 | Yatindra Joshi | Pharmaceutical composition which produces irritation |
| JP4354678B2 (ja) * | 2002-08-28 | 2009-10-28 | 久光製薬株式会社 | 貼付剤 |
| US6913768B2 (en) | 2002-09-24 | 2005-07-05 | Shire Laboratories, Inc. | Sustained release delivery of amphetamine salts |
| CA2507522C (en) | 2002-12-13 | 2015-02-24 | Durect Corporation | Oral drug delivery system |
| RU2356580C2 (ru) * | 2003-10-28 | 2009-05-27 | Новен Фармасьютикалз, Инк | Композиции и способы, обеспечивающие контролируемую потерю лекарственных средств и доставку в системах трансдермальной доставки лекарственных средств |
| EP1845984B1 (en) * | 2005-01-20 | 2013-01-09 | Institute for Molecular Medicine, Inc. | Methylphenidate derivatives and uses of them |
| EP1845780B1 (en) * | 2005-01-20 | 2011-07-27 | Institute for Molecular Medicine, Inc. | Uses of methylphenidate derivatives |
| KR101333100B1 (ko) * | 2005-12-23 | 2013-11-27 | 에피나믹스 게엠베하 | 폴리우레탄 군으로부터의 필름-형성 헤어 케어 폴리머의 용도 및 폴리머를 포함하는 약학적 제제와 패치 |
| US9393218B2 (en) * | 2005-12-23 | 2016-07-19 | Epinamics Gmbh | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers |
| RU2008138595A (ru) * | 2006-02-27 | 2010-04-10 | Ноувен Фамэсьютикэлз, Инк. (US) | Гибкая ограниченная система для трансдермального введения скополамина, способ ее изготовления и способ трансдермальной доставки скополамина с ее помощью |
| RU2414209C2 (ru) * | 2006-05-01 | 2011-03-20 | Колгейт-Палмолив Компани | Композиция с силиконовым композитом для ухода за полостью рта |
| WO2008103538A1 (en) * | 2007-02-21 | 2008-08-28 | Connected Health Systems, Llc | Treating adhd and other diseases involving inflammation |
| CN101902996B (zh) * | 2007-10-15 | 2014-11-26 | 阿尔扎公司 | 芬太尼的一天更换一次透皮施用 |
| FR2924349B1 (fr) | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
| FR2924350B1 (fr) * | 2007-12-03 | 2010-08-13 | Dbv Tech | Procede et compositions pour la vaccination par voie cutanee |
| EP2067471B1 (en) | 2007-12-06 | 2018-02-14 | Durect Corporation | Oral pharmaceutical dosage forms |
| ES2524696T3 (es) * | 2007-12-31 | 2014-12-11 | Acclarent, Inc. | Vendaje del tejido de la mucosa y método de uso |
| FR2926466B1 (fr) * | 2008-01-23 | 2010-11-12 | Dbv Tech | Procede de fabrication de patchs par electrospray |
| US8217047B2 (en) | 2008-05-27 | 2012-07-10 | Dmi Acquisition Corp. | Therapeutic methods and compounds |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| JP5155128B2 (ja) * | 2008-12-11 | 2013-02-27 | 日東電工株式会社 | メチルフェニデート貼付製剤 |
| CA2976789C (en) * | 2009-06-05 | 2019-12-31 | Megtec Systems, Inc. | Method of drying a web of printed material |
| EP2364695A1 (en) | 2010-02-10 | 2011-09-14 | Nitto Denko Corporation | Methylphenidate patch preparation |
| US20110200663A1 (en) * | 2010-02-12 | 2011-08-18 | Nitto Denko Corporation | Methylphenidate patch preparation |
| US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| DK3272342T3 (da) | 2011-03-23 | 2021-06-07 | Ironshore Pharmaceuticals & Dev Inc | Fremgangsmåder og sammensætninger til behandling af opmærksomhedsforstyrrelse |
| US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
| US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| RS55812B1 (sr) | 2011-07-28 | 2017-08-31 | Kempharm Inc | Metilfenidatni prolekovi, procesi za njihovo dobijanje i njihova primena |
| CA2891467A1 (en) | 2012-10-15 | 2014-04-24 | Noven Pharmaceuticals, Inc. | Compositions and methods for the transdermal delivery of methylphenidate |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| TW201431554A (zh) | 2012-12-28 | 2014-08-16 | Noven Pharma | 左炔諾孕酮(levonorgestrel)及乙烯雌二醇之經皮藥物遞送系統 |
| JP6359032B2 (ja) | 2012-12-28 | 2018-07-18 | ノーヴェン ファーマシューティカルズ インコーポレイテッド | 経皮薬物送達用のマルチポリマー組成物 |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| WO2014159582A1 (en) | 2013-03-14 | 2014-10-02 | Noven Pharmaceuticals, Inc | Amphetamine transdermal compositions with acrylic block copolymer |
| AR095259A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria |
| AR095260A1 (es) | 2013-03-15 | 2015-09-30 | Noven Pharma | Composiciones de anfetaminas transdérmicas estables y métodos de fabricación |
| AU2014233453A1 (en) | 2013-03-15 | 2015-10-01 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| CN106163514B (zh) | 2013-12-25 | 2019-07-19 | 藤本株式会社 | 注意缺陷和多动性障碍的预防及治疗剂 |
| US9980921B2 (en) * | 2016-06-30 | 2018-05-29 | Taho Pharmaceuticals Ltd. | Transdermal delivery system containing methylphenidate or its salts and methods thereof |
| CA3028450A1 (en) | 2016-07-06 | 2018-01-11 | Durect Corporation | Oral dosage form with drug composition, barrier layer and drug layer |
| CN106511264A (zh) * | 2016-11-15 | 2017-03-22 | 北京万全德众医药生物技术有限公司 | 一种盐酸哌甲酯口服溶液剂及其制备方法 |
| EP3551619B1 (en) | 2016-12-11 | 2024-03-06 | Zevra Therapeutics, Inc. | Compositions comprising methylphenidate-prodrugs, processes of making and using the same |
| EP3598982A1 (en) | 2018-07-23 | 2020-01-29 | Centre National De La Recherche Scientifique | Bioconjugates of neuropeptides derivatives |
| JP7600661B2 (ja) * | 2020-12-11 | 2024-12-17 | artience株式会社 | 貼付剤 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2957880A (en) | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| US4310509A (en) | 1979-07-31 | 1982-01-12 | Minnesota Mining And Manufacturing Company | Pressure-sensitive adhesive having a broad spectrum antimicrobial therein |
| US4655767A (en) | 1984-10-29 | 1987-04-07 | Dow Corning Corporation | Transdermal drug delivery devices with amine-resistant silicone adhesives |
| US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5474783A (en) | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| DE3910578A1 (de) * | 1989-03-29 | 1990-10-04 | Schering Ag | Mittel zur transdermalen applikation enthaltend gestoden |
| JP2693212B2 (ja) * | 1989-03-28 | 1997-12-24 | 日東電工株式会社 | 疾患治療用テープ製剤 |
| WO1992021333A2 (en) * | 1991-05-24 | 1992-12-10 | Pharmavene, Inc. | Treatment of drug withdrawal symptoms and drug craving with type b monoamine oxidase inhibitors |
| US5629019A (en) | 1992-02-27 | 1997-05-13 | Alza Corporation | Formulations with hydrophobic permeation enhancers |
| EP0652774B1 (en) | 1992-07-28 | 1997-05-07 | The Procter & Gamble Company | Pharmaceutical composition for topical use containing a crosslinked cationic polymer and an alkoxylated ether |
| CH691209A5 (de) | 1993-09-06 | 2001-05-15 | Scherrer Inst Paul | Herstellungsverfahren für einen Polmerelektrolyten und elektrochemische Zelle mit diesem Polymerelektrolyten. |
| EP0689920B1 (de) | 1994-06-29 | 1999-10-13 | Hennecke GmbH | Verfahren und Vorrichtung zum kontinuierlichen Herstellen von Schaumstoffblöcken oder Schaumstoffbahnen |
| US5601839A (en) | 1995-04-26 | 1997-02-11 | Theratech, Inc. | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
| US5780050A (en) | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
| WO1998039042A1 (en) | 1997-03-07 | 1998-09-11 | Jackson Richard R | Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods |
| GB9711032D0 (en) | 1997-05-30 | 1997-07-23 | Johnson Matthey Plc | Compound as a stimulant for the central nervous system |
| US6684641B2 (en) | 1999-12-15 | 2004-02-03 | Osaka Gas Co., Ltd. | Fluid distributor, burner device, gas turbine engine, and cogeneration system |
-
1998
- 1998-09-30 US US09/163,351 patent/US6210705B1/en not_active Expired - Lifetime
- 1998-12-14 ES ES98963170T patent/ES2219926T3/es not_active Expired - Lifetime
- 1998-12-14 IL IL13676098A patent/IL136760A0/xx not_active IP Right Cessation
- 1998-12-14 EP EP10011358.8A patent/EP2314288B1/en not_active Expired - Lifetime
- 1998-12-14 TW TW087120741A patent/TWI242452B/zh not_active IP Right Cessation
- 1998-12-14 CA CA002315237A patent/CA2315237C/en not_active Expired - Lifetime
- 1998-12-14 JP JP2000538677A patent/JP4316800B2/ja not_active Expired - Lifetime
- 1998-12-14 KR KR1020007006477A patent/KR100633348B1/ko not_active Expired - Fee Related
- 1998-12-14 BR BR9814282-8A patent/BR9814282A/pt not_active Application Discontinuation
- 1998-12-14 HK HK03101632.9A patent/HK1049447A1/zh unknown
- 1998-12-14 SI SI9820083A patent/SI20360B/sl not_active IP Right Cessation
- 1998-12-14 AT AT98963170T patent/ATE260652T1/de active
- 1998-12-14 CZ CZ20002209A patent/CZ300535B6/cs not_active IP Right Cessation
- 1998-12-14 AU AU18249/99A patent/AU752027B2/en not_active Ceased
- 1998-12-14 ES ES10011358.8T patent/ES2452517T3/es not_active Expired - Lifetime
- 1998-12-14 HU HU0004539A patent/HU226615B1/hu not_active IP Right Cessation
- 1998-12-14 TW TW092128573A patent/TWI244396B/zh not_active IP Right Cessation
- 1998-12-14 DE DE69822199T patent/DE69822199T2/de not_active Expired - Lifetime
- 1998-12-14 PT PT98963170T patent/PT1037615E/pt unknown
- 1998-12-14 DK DK98963170T patent/DK1037615T3/da active
- 1998-12-14 WO PCT/US1998/026560 patent/WO1999030694A2/en not_active Ceased
- 1998-12-14 CZ CZ2009-132A patent/CZ305817B6/cs not_active IP Right Cessation
- 1998-12-14 TR TR2000/01736T patent/TR200001736T2/xx unknown
- 1998-12-14 NZ NZ505689A patent/NZ505689A/xx not_active IP Right Cessation
- 1998-12-14 EP EP98963170A patent/EP1037615B1/en not_active Expired - Lifetime
- 1998-12-14 PL PL98341596A patent/PL195315B1/pl unknown
- 1998-12-14 RU RU2000119097/15A patent/RU2233156C2/ru not_active IP Right Cessation
- 1998-12-14 CN CN98813634A patent/CN1368876A/zh active Pending
- 1998-12-15 PE PE1998001219A patent/PE20000120A1/es not_active Application Discontinuation
- 1998-12-15 AR ARP980106392A patent/AR014062A1/es not_active Application Discontinuation
-
2000
- 2000-06-15 NO NO20003096A patent/NO329974B1/no not_active IP Right Cessation
- 2000-07-17 LV LVP-00-92A patent/LV12558B/en unknown
- 2000-07-18 US US09/618,626 patent/US6348211B1/en not_active Expired - Lifetime
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2008
- 2008-11-13 JP JP2008291364A patent/JP2009073856A/ja active Pending
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2012
- 2012-12-26 JP JP2012282405A patent/JP2013056944A/ja active Pending
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