LV10927B - Sustained-release preparation - Google Patents

Sustained-release preparation Download PDF

Info

Publication number: LV10927B
Authority: LV; Latvia
Prior art keywords: group; acid; medicament; copolymer; peptide
Prior art date: 1992-12-07

Application number

LVP-95-160A

Other languages

English (en)

Latvian (lv)

Other versions

LV10927A (lv

Inventor

Shigeru Kamei

Yasutaka Igari

Yasuaki Ogawa

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-07

Filing date

1995-06-07

Publication date

1996-04-20

1995-06-07 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1995-12-20 Publication of LV10927A publication Critical patent/LV10927A/xx

1996-04-20 Publication of LV10927B publication Critical patent/LV10927B/en

Links

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COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
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125000000168 pyrrolyl group Chemical group 0.000 description 1
125000005493 quinolyl group Chemical group 0.000 description 1
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239000004474 valine Substances 0.000 description 1
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239000008096 xylene Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Reproductive Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

LVP-95-160A 1992-12-07 1995-06-07 Sustained-release preparation LV10927B (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP32707092		1992-12-07
JP1897893		1993-02-05
JP14513493		1993-06-16
PCT/JP1993/001773 WO1994013317A1 (fr)	1992-12-07	1993-12-07	Preparation a liberation prolongee

Publications (2)

Publication Number	Publication Date
LV10927A LV10927A (lv)	1995-12-20
LV10927B true LV10927B (en)	1996-04-20

Family

ID=27282444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LVP-95-160A LV10927B (en)	1992-12-07	1995-06-07	Sustained-release preparation

Country Status (23)

Country	Link
US (7)	US5480868A (sv)
EP (2)	EP0601799B1 (sv)
JP (1)	JP3725906B2 (sv)
KR (2)	KR100305951B1 (sv)
CN (2)	CN1099893C (sv)
AT (2)	ATE203910T1 (sv)
AU (1)	AU669939B2 (sv)
CA (1)	CA2110730C (sv)
DE (2)	DE69330547T2 (sv)
DK (2)	DK1088555T3 (sv)
EE (1)	EE03117B1 (sv)
ES (2)	ES2158856T3 (sv)
FI (2)	FI935471A7 (sv)
GE (1)	GEP19991600B (sv)
GR (1)	GR3037085T3 (sv)
LV (1)	LV10927B (sv)
MX (1)	MX9307686A (sv)
NO (1)	NO310704B1 (sv)
NZ (1)	NZ250349A (sv)
PT (2)	PT601799E (sv)
SG (1)	SG46283A1 (sv)
TW (1)	TW333456B (sv)
WO (1)	WO1994013317A1 (sv)

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1993
- 1993-11-24 TW TW082109889A patent/TW333456B/zh active
- 1993-12-01 AU AU52113/93A patent/AU669939B2/en not_active Ceased
- 1993-12-01 GE GEAP19931669A patent/GEP19991600B/en unknown
- 1993-12-03 SG SG1996002095A patent/SG46283A1/en unknown
- 1993-12-03 NZ NZ250349A patent/NZ250349A/en unknown
- 1993-12-03 DE DE69330547T patent/DE69330547T2/de not_active Expired - Lifetime
- 1993-12-03 AT AT93309681T patent/ATE203910T1/de not_active IP Right Cessation
- 1993-12-03 ES ES93309681T patent/ES2158856T3/es not_active Expired - Lifetime
- 1993-12-03 DK DK00203850T patent/DK1088555T3/da active
- 1993-12-03 ES ES00203850T patent/ES2238247T3/es not_active Expired - Lifetime
- 1993-12-03 DE DE69333817T patent/DE69333817T2/de not_active Expired - Lifetime
- 1993-12-03 PT PT93309681T patent/PT601799E/pt unknown
- 1993-12-03 PT PT00203850T patent/PT1088555E/pt unknown
- 1993-12-03 DK DK93309681T patent/DK0601799T3/da active
- 1993-12-03 EP EP93309681A patent/EP0601799B1/en not_active Expired - Lifetime
- 1993-12-03 AT AT00203850T patent/ATE295733T1/de active
- 1993-12-03 EP EP00203850A patent/EP1088555B1/en not_active Expired - Lifetime
- 1993-12-06 NO NO19934423A patent/NO310704B1/no unknown
- 1993-12-06 MX MX9307686A patent/MX9307686A/es unknown
- 1993-12-06 CA CA002110730A patent/CA2110730C/en not_active Expired - Lifetime
- 1993-12-07 KR KR1019930026743A patent/KR100305951B1/ko not_active Expired - Fee Related
- 1993-12-07 CN CN93121140A patent/CN1099893C/zh not_active Expired - Fee Related
- 1993-12-07 FI FI935471A patent/FI935471A7/sv unknown
- 1993-12-07 WO PCT/JP1993/001773 patent/WO1994013317A1/ja not_active Ceased
- 1993-12-07 JP JP30665993A patent/JP3725906B2/ja not_active Expired - Fee Related
- 1993-12-07 US US08/162,698 patent/US5480868A/en not_active Expired - Lifetime
1994
- 1994-11-17 EE EE9400331A patent/EE03117B1/xx not_active IP Right Cessation
1995
- 1995-06-06 US US08/471,382 patent/US5668111A/en not_active Expired - Lifetime
- 1995-06-07 LV LVP-95-160A patent/LV10927B/en unknown
1997
- 1997-07-14 US US08/892,315 patent/US5972891A/en not_active Expired - Lifetime
1999
- 1999-08-31 US US09/386,232 patent/US6528093B1/en not_active Expired - Fee Related
2000
- 2000-09-01 KR KR1020000051490A patent/KR100319425B1/ko not_active Expired - Lifetime
2001
- 2001-10-31 GR GR20010401958T patent/GR3037085T3/el not_active IP Right Cessation
- 2001-12-26 US US10/025,967 patent/US20020147150A1/en not_active Abandoned
2002
- 2002-03-22 CN CNB021082065A patent/CN100488560C/zh not_active Expired - Lifetime
- 2002-04-23 US US10/127,558 patent/US7048947B2/en not_active Expired - Fee Related
2003
- 2003-02-04 FI FI20030166A patent/FI116196B/sv not_active IP Right Cessation
2008
- 2008-10-07 US US12/285,494 patent/US20090048180A1/en not_active Abandoned

Also Published As

Publication number	Publication date
TW333456B (en)	1998-06-11
KR100305951B1 (ko)	2001-11-30
GEP19991600B (en)	1999-04-29
US5668111A (en)	1997-09-16
AU5211393A (en)	1994-06-16
ES2158856T3 (es)	2001-09-16
FI20030166L (sv)	2003-02-04
EE03117B1 (et)	1998-10-15
AU669939B2 (en)	1996-06-27
FI935471A7 (sv)	1994-06-08
DE69330547T2 (de)	2001-11-22
EP0601799B1 (en)	2001-08-08
US5480868A (en)	1996-01-02
CA2110730A1 (en)	1994-06-08
CN1428144A (zh)	2003-07-09
NO310704B1 (no)	2001-08-20
HK1037519A1 (en)	2002-02-15
US6528093B1 (en)	2003-03-04
DE69333817D1 (de)	2005-06-23
US7048947B2 (en)	2006-05-23
US20030039698A1 (en)	2003-02-27
EP0601799A1 (en)	1994-06-15
KR100319425B1 (ko)	2002-01-09
DE69330547D1 (de)	2001-09-13
CN100488560C (zh)	2009-05-20
NO934423L (no)	1994-06-08
JPH0797334A (ja)	1995-04-11
KR20010016379A (ko)	2001-03-05
DK1088555T3 (da)	2005-07-04
US20020147150A1 (en)	2002-10-10
ATE203910T1 (de)	2001-08-15
FI116196B (sv)	2005-10-14
EP1088555B1 (en)	2005-05-18
SG46283A1 (en)	1998-02-20
DE69333817T2 (de)	2006-02-02
GR3037085T3 (en)	2002-01-31
CA2110730C (en)	2008-09-16
NZ250349A (en)	1994-12-22
DK0601799T3 (da)	2001-10-01
ES2238247T3 (es)	2005-09-01
WO1994013317A1 (fr)	1994-06-23
NO934423D0 (no)	1993-12-06
ATE295733T1 (de)	2005-06-15
US20020173467A1 (en)	2002-11-21
JP3725906B2 (ja)	2005-12-14
MX9307686A (es)	1994-06-30
KR940013530A (ko)	1994-07-15
US20090048180A1 (en)	2009-02-19
CN1096221A (zh)	1994-12-14
CN1099893C (zh)	2003-01-29
FI935471A0 (fi)	1993-12-07
PT1088555E (pt)	2005-07-29
US5972891A (en)	1999-10-26
PT601799E (pt)	2001-12-28
LV10927A (lv)	1995-12-20
EP1088555A1 (en)	2001-04-04

Publication	Publication Date	Title
US5480868A (en)	1996-01-02	Sustained-release preparation
ES2256276T3 (es)	2006-07-16	Polimero de acido lactico y procedimiento para su produccion.
RU2301661C2 (ru)	2007-06-27	Композиция с регулируемым высвобождением и способ ее получения
KR100988178B1 (ko)	2010-10-18	서방성 조성물 및 이의 제조 방법
RU2207151C2 (ru)	2003-06-27	Иммобилизованный и стабилизированный комплекс антагониста, лютеинизирующий гормон высвобождающего гормона, способ его получения, лекарственное средство
CA2671670C (en)	2015-02-10	Sustained-release composition and method for producing the same
KR20020012312A (ko)	2002-02-15	서방성 조성물, 그의 제조 방법 및 용도
RU2128055C1 (ru)	1999-03-27	Фармацевтическая композиция замедленного высвобождения и способ ее получения
CN100463672C (zh)	2009-02-25	制备大量微胶囊的方法
NO323428B1 (no)	2007-04-30	Fremgangsmate for fremstilling av mikrokapsel
HK1037519B (en)	2005-10-21	Sustained-release leuprorelin preparation