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LT3169666T - Pakeistieji azaspiro(4.5)dekano dariniai - Google Patents

Pakeistieji azaspiro(4.5)dekano dariniai

Info

Publication number
LT3169666T
LT3169666T LTEP15738274.8T LT15738274T LT3169666T LT 3169666 T LT3169666 T LT 3169666T LT 15738274 T LT15738274 T LT 15738274T LT 3169666 T LT3169666 T LT 3169666T
Authority
LT
Lithuania
Prior art keywords
decane derivatives
substituted azaspiro
azaspiro
substituted
decane
Prior art date
Application number
LTEP15738274.8T
Other languages
English (en)
Inventor
Anita Wegert
Sven KÜHNERT
René KOENIGS
Bert Nolte
Klaus Linz
Stephanie Harlfinger
Babette-Yvonne Kögel
Paul Ratcliffe
Fritz Theil
Olga GRÖGER
Birgit Braun
Original Assignee
GrĆ¼nenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GrĆ¼nenthal GmbH filed Critical GrĆ¼nenthal GmbH
Publication of LT3169666T publication Critical patent/LT3169666T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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LTEP15738274.8T 2014-07-15 2015-07-14 Pakeistieji azaspiro(4.5)dekano dariniai LT3169666T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14002439 2014-07-15
PCT/EP2015/001445 WO2016008582A1 (en) 2014-07-15 2015-07-14 Substituted azaspiro(4.5)decane derivatives

Publications (1)

Publication Number Publication Date
LT3169666T true LT3169666T (lt) 2018-08-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15738274.8T LT3169666T (lt) 2014-07-15 2015-07-14 Pakeistieji azaspiro(4.5)dekano dariniai

Country Status (20)

Country Link
US (1) US10214520B2 (lt)
EP (1) EP3169666B1 (lt)
JP (1) JP6509321B2 (lt)
CN (1) CN106660954A (lt)
AU (1) AU2015291467B2 (lt)
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