LT3169665T - Pakeistieji aza-spiro(4.5)dekano dariniai - Google Patents
Pakeistieji aza-spiro(4.5)dekano dariniaiInfo
- Publication number
- LT3169665T LT3169665T LTEP15737988.4T LT15737988T LT3169665T LT 3169665 T LT3169665 T LT 3169665T LT 15737988 T LT15737988 T LT 15737988T LT 3169665 T LT3169665 T LT 3169665T
- Authority
- LT
- Lithuania
- Prior art keywords
- spiro
- decane derivatives
- substituted aza
- aza
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14002438 | 2014-07-15 | ||
| PCT/EP2015/001446 WO2016008583A1 (de) | 2014-07-15 | 2015-07-14 | Substituierte aza-spiro(4.5)decan-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3169665T true LT3169665T (lt) | 2018-07-10 |
Family
ID=51211483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP15737988.4T LT3169665T (lt) | 2014-07-15 | 2015-07-14 | Pakeistieji aza-spiro(4.5)dekano dariniai |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10202345B2 (lt) |
| EP (1) | EP3169665B1 (lt) |
| JP (1) | JP6490187B2 (lt) |
| CN (1) | CN106536514A (lt) |
| AU (1) | AU2015291468B2 (lt) |
| BR (1) | BR112017000766A2 (lt) |
| CA (1) | CA2955073A1 (lt) |
| CY (1) | CY1120443T1 (lt) |
| DK (1) | DK3169665T3 (lt) |
| EA (1) | EA201790186A1 (lt) |
| ES (1) | ES2680820T3 (lt) |
| HR (1) | HRP20180940T1 (lt) |
| HU (1) | HUE039604T2 (lt) |
| LT (1) | LT3169665T (lt) |
| MX (1) | MX2017000519A (lt) |
| PL (1) | PL3169665T3 (lt) |
| PT (1) | PT3169665T (lt) |
| RS (1) | RS57388B1 (lt) |
| SI (1) | SI3169665T1 (lt) |
| TR (1) | TR201809663T4 (lt) |
| TW (1) | TW201607923A (lt) |
| WO (1) | WO2016008583A1 (lt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE040133T2 (hu) * | 2014-07-15 | 2019-02-28 | Gruenenthal Gmbh | Szubsztituált azaspiro(4.5)dekán származékok |
| WO2019152688A1 (en) * | 2018-01-31 | 2019-08-08 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA827340B (en) * | 1981-11-12 | 1983-10-26 | Upjohn Co | Analgesic 1-oxa-,aza-and thia-spirocyclic compounds |
| DE3928182A1 (de) | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
| DE19608653A1 (de) | 1996-03-06 | 1997-09-11 | Thomae Gmbh Dr K | Pyrimido[5,4-d]pyrimidine, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| EA200000385A1 (ru) | 1997-11-04 | 2000-10-30 | Пфайзер Продактс Инк. | Терапевтически активные соединения на основе индазольной биоизостерической замены катехина в ингибиторах фосфодиэстеразы типа vi (pde4) |
| JP2003525207A (ja) * | 1999-06-02 | 2003-08-26 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 薬剤として有用なアミノ複素環 |
| HUP9902374A3 (en) | 1999-07-15 | 2002-11-28 | Sanofi Aventis | Process for producing spiro[(4-cyclohexanone)-[3h]indol-2'[1'h]-on derivatives and intermediates |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DK2272813T3 (en) | 2001-04-24 | 2017-02-27 | Massachusetts Inst Of Tech (Mit) | COPPER CATALYST CREATION OF CARBON OXYGEN COMPOUNDS |
| DE10210190A1 (de) * | 2002-03-07 | 2003-09-25 | Sanol Arznei Schwarz Gmbh | Aza-Spiroverbindungen |
| EP1601674B1 (en) | 2002-09-09 | 2012-08-08 | Janssen Pharmaceutica NV | Hydroxyalkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10252665A1 (de) * | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate |
| DE10360792A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10360793A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE102004023635A1 (de) | 2004-05-10 | 2006-04-13 | Grünenthal GmbH | Heteroarylsubstituierte Cyclohexyl-1,4-diamin-Derivate |
| DE102004039382A1 (de) | 2004-08-13 | 2006-02-23 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE602005020656D1 (de) | 2004-09-13 | 2010-05-27 | Merck Sharp & Dohme | Bicyclische anilidspirolactame als antagonisten des cgrp-rezeptors |
| JP2008513476A (ja) | 2004-09-17 | 2008-05-01 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | ｃ−Ｋｉｔ癌原遺伝子阻害剤としての（スピロシクリルアミド）アミノチオフェン化合物 |
| DE102005016460A1 (de) | 2005-04-11 | 2006-10-19 | Grünenthal GmbH | Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit |
| DE102005038141A1 (de) * | 2005-08-12 | 2007-02-15 | Grünenthal GmbH | Substituierte 8-(3-Aminopropyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-on-Derivate |
| TW200800999A (en) | 2005-09-06 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
| AR057579A1 (es) | 2005-11-23 | 2007-12-05 | Merck & Co Inc | Compuestos espirociclicos como inhibidores de histona de acetilasa (hdac) |
| JP5225098B2 (ja) | 2005-12-14 | 2013-07-03 | ブリストル−マイヤーズ スクイブ カンパニー | 第ＸＩａ因子インヒビターとしてのアリールプロピオンアミド、アリールアクリルアミド、アリールプロピンアミド、またはアリールメチルウレアアナログ |
| DE102005061428A1 (de) | 2005-12-22 | 2007-08-16 | Grünenthal GmbH | Substituierte Cyclohexylmethyl-Derivate |
| ATE471311T1 (de) | 2006-04-25 | 2010-07-15 | Lilly Co Eli | Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1 |
| DE102006019597A1 (de) | 2006-04-27 | 2007-10-31 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE102006033114A1 (de) | 2006-07-18 | 2008-01-24 | Grünenthal GmbH | Spirocyclische Azaindol-Derivate |
| DE102006033109A1 (de) | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituierte Heteroaryl-Derivate |
| EP2066674B1 (en) | 2006-09-18 | 2010-06-30 | F.Hoffmann-La Roche Ag | Octahydropyrrolo [3, 4-c] pyrrole derivatives and their use as antiviral agents |
| AU2007299818B2 (en) | 2006-09-22 | 2012-08-02 | Janssen Pharmaceutica N.V. | Spiro benzazepines used as vasopressin antagonists |
| DE102007009235A1 (de) | 2007-02-22 | 2008-09-18 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE102007009319A1 (de) | 2007-02-22 | 2008-08-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| BRPI0808025A2 (pt) | 2007-03-01 | 2014-06-24 | Mitsubishi Tanabe Pharma Corp | Composto de benzimidazol e uso farmacêutico do mesmo |
| GB0707934D0 (en) | 2007-04-24 | 2007-05-30 | Glaxo Group Ltd | Chemical compounds |
| CA2716352C (en) | 2008-03-06 | 2013-05-28 | Amgen Inc. | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders |
| PT2260042E (pt) | 2008-03-27 | 2011-12-06 | Gruenenthal Gmbh | Derivados de ciclo-hexano espirocíclicos substituídos |
| CN103214376A (zh) * | 2008-03-27 | 2013-07-24 | 格吕伦塔尔有限公司 | 取代的4-氨基环己烷衍生物 |
| CA2719739A1 (en) | 2008-03-27 | 2009-10-01 | Sven Frormann | Hydroxymethylcyclohexylamines |
| AR071067A1 (es) | 2008-03-27 | 2010-05-26 | Gruenenthal Chemie | Ciclohexildiaminas sustituidas |
| DK2257526T3 (da) | 2008-03-27 | 2012-02-06 | Gruenenthal Gmbh | Spiro(5,5)undecan-derivater |
| AU2009277095B2 (en) | 2008-07-30 | 2012-09-06 | Purdue Pharma L.P. | Buprenorphine analogs |
| UA107943C2 (xx) | 2009-11-16 | 2015-03-10 | Lilly Co Eli | Сполуки спіропіперидину як антагоністи рецептора orl-1 |
| GB201111775D0 (en) | 2011-07-08 | 2011-08-24 | Univ Bath | Compounds and uses thereof |
| EP3736265A1 (en) * | 2011-10-20 | 2020-11-11 | Oryzon Genomics, S.A. | (hetero)aryl cyclopropylamine compounds as lsd1 inhibitors |
-
2015
- 2015-07-13 TW TW104122500A patent/TW201607923A/zh unknown
- 2015-07-14 PT PT157379884T patent/PT3169665T/pt unknown
- 2015-07-14 CA CA2955073A patent/CA2955073A1/en not_active Abandoned
- 2015-07-14 EA EA201790186A patent/EA201790186A1/ru unknown
- 2015-07-14 WO PCT/EP2015/001446 patent/WO2016008583A1/de not_active Ceased
- 2015-07-14 EP EP15737988.4A patent/EP3169665B1/de not_active Not-in-force
- 2015-07-14 TR TR2018/09663T patent/TR201809663T4/tr unknown
- 2015-07-14 MX MX2017000519A patent/MX2017000519A/es unknown
- 2015-07-14 CN CN201580038748.3A patent/CN106536514A/zh active Pending
- 2015-07-14 SI SI201530295T patent/SI3169665T1/en unknown
- 2015-07-14 PL PL15737988T patent/PL3169665T3/pl unknown
- 2015-07-14 LT LTEP15737988.4T patent/LT3169665T/lt unknown
- 2015-07-14 JP JP2017502128A patent/JP6490187B2/ja not_active Expired - Fee Related
- 2015-07-14 HU HUE15737988A patent/HUE039604T2/hu unknown
- 2015-07-14 ES ES15737988T patent/ES2680820T3/es active Active
- 2015-07-14 DK DK15737988.4T patent/DK3169665T3/en active
- 2015-07-14 BR BR112017000766A patent/BR112017000766A2/pt not_active Application Discontinuation
- 2015-07-14 AU AU2015291468A patent/AU2015291468B2/en not_active Ceased
- 2015-07-14 RS RS20180789A patent/RS57388B1/sr unknown
- 2015-07-14 HR HRP20180940TT patent/HRP20180940T1/hr unknown
- 2015-07-15 US US14/799,872 patent/US10202345B2/en not_active Expired - Fee Related
-
2018
- 2018-07-11 CY CY20181100722T patent/CY1120443T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2955073A1 (en) | 2016-01-21 |
| WO2016008583A1 (de) | 2016-01-21 |
| US20160016903A1 (en) | 2016-01-21 |
| ES2680820T3 (es) | 2018-09-11 |
| JP6490187B2 (ja) | 2019-03-27 |
| TR201809663T4 (tr) | 2018-07-23 |
| EA201790186A1 (ru) | 2017-07-31 |
| PT3169665T (pt) | 2018-07-12 |
| DK3169665T3 (en) | 2018-06-25 |
| JP2017520599A (ja) | 2017-07-27 |
| SI3169665T1 (en) | 2018-08-31 |
| MX2017000519A (es) | 2017-05-01 |
| US10202345B2 (en) | 2019-02-12 |
| EP3169665A1 (de) | 2017-05-24 |
| HRP20180940T1 (hr) | 2018-07-27 |
| TW201607923A (zh) | 2016-03-01 |
| AU2015291468B2 (en) | 2019-01-24 |
| CY1120443T1 (el) | 2019-07-10 |
| AU2015291468A1 (en) | 2017-03-02 |
| HUE039604T2 (hu) | 2019-01-28 |
| PL3169665T3 (pl) | 2018-12-31 |
| EP3169665B1 (de) | 2018-05-09 |
| CN106536514A (zh) | 2017-03-22 |
| WO2016008583A8 (de) | 2016-03-31 |
| RS57388B1 (sr) | 2018-09-28 |
| BR112017000766A2 (pt) | 2017-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL265752A (en) | Spirocyclic compounds | |
| ZA201800826B (en) | Substituted oxopyridine derivatives | |
| GB2550864B (en) | Well | |
| IL252053A0 (en) | Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders | |
| IL260488B (en) | History of 8-amino-2-oxo-3,1-diaza-spiro-[5.4]-decane | |
| GB201416346D0 (en) | Spirocyclic derivatives | |
| GB201416352D0 (en) | Spirocyclic derivatives | |
| PL3233890T3 (pl) | Pestiwirus | |
| IL254662A0 (en) | Spirocyclic compounds | |
| IL267145B (en) | Spiropyridine derivatives | |
| HUE040133T2 (hu) | Szubsztituált azaspiro(4.5)dekán származékok | |
| SG11201803584RA (en) | 1,4-dicarbonyl-piperidyl derivatives | |
| IL258217A (en) | 2,3,4,5 tetrahydropyridin-6-amine derivatives | |
| PL3169665T3 (pl) | Podstawione pochodne aza-spiro(4,5)dekanu | |
| GB2555413B (en) | Sampling circuitry | |
| PT3319956T (pt) | Derivados de oxopiridina substituída | |
| HK40013278A (en) | Spirocyclic compounds | |
| AU5625P (en) | BG-3.324 Fragaria Xananassa | |
| GB201615095D0 (en) | Match strikes | |
| GB201614244D0 (en) | Tjti&tjtd | |
| GB201614243D0 (en) | Tjti&tjtd | |
| GB201614173D0 (en) | Tjti&tjtd | |
| GB201611093D0 (en) | . | |
| GB201408093D0 (en) | The vores heltian white hole. | |
| GB201605155D0 (en) | Supervoucher.com |