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MX2017000520A - Derivados de azaspiro(4.5)decano sustituido. - Google Patents

Derivados de azaspiro(4.5)decano sustituido.

Info

Publication number
MX2017000520A
MX2017000520A MX2017000520A MX2017000520A MX2017000520A MX 2017000520 A MX2017000520 A MX 2017000520A MX 2017000520 A MX2017000520 A MX 2017000520A MX 2017000520 A MX2017000520 A MX 2017000520A MX 2017000520 A MX2017000520 A MX 2017000520A
Authority
MX
Mexico
Prior art keywords
decane derivatives
substituted azaspiro
substituted
compounds
preparation
Prior art date
Application number
MX2017000520A
Other languages
English (en)
Inventor
Kögel Babette-Yvonne
Kühnert Sven
Nolte Bert
Michael Koenigs René
WEGERT Anita
Linz Klaus
Harlfinger Stephanie
Ratcliffe Paul
Theil Fritz
Gröger Olga
Braun Birgit
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MX2017000520A publication Critical patent/MX2017000520A/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract

La invención se relación con derivados de ciclohexano espirocíclico sustituidos que tienen una afinidad para el receptor del opioide µ y/o el receptor de ORL1, los procesos para la preparación de los mismos, los medicamentos que contienen estos compuestos y el uso de estos compuestos para la preparación de medicamentos.
MX2017000520A 2014-07-15 2015-07-14 Derivados de azaspiro(4.5)decano sustituido. MX2017000520A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14002439 2014-07-15
PCT/EP2015/001445 WO2016008582A1 (en) 2014-07-15 2015-07-14 Substituted azaspiro(4.5)decane derivatives

Publications (1)

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MX2017000520A true MX2017000520A (es) 2017-05-01

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MX2017000520A MX2017000520A (es) 2014-07-15 2015-07-14 Derivados de azaspiro(4.5)decano sustituido.

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