LT2960238T - Monociklinis piridino darinys - Google Patents
Monociklinis piridino darinysInfo
- Publication number
- LT2960238T LT2960238T LTEP14754294.8T LT14754294T LT2960238T LT 2960238 T LT2960238 T LT 2960238T LT 14754294 T LT14754294 T LT 14754294T LT 2960238 T LT2960238 T LT 2960238T
- Authority
- LT
- Lithuania
- Prior art keywords
- pyridine derivative
- monocyclic pyridine
- monocyclic
- derivative
- pyridine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361766922P | 2013-02-20 | 2013-02-20 | |
| PCT/JP2014/053819 WO2014129477A1 (ja) | 2013-02-20 | 2014-02-18 | 単環ピリジン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2960238T true LT2960238T (lt) | 2017-07-10 |
Family
ID=51351646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14754294.8T LT2960238T (lt) | 2013-02-20 | 2014-02-18 | Monociklinis piridino darinys |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US8933099B2 (lt) |
| EP (1) | EP2960238B1 (lt) |
| JP (2) | JP5600229B1 (lt) |
| KR (1) | KR102050128B1 (lt) |
| CN (1) | CN105073730B (lt) |
| AR (1) | AR094812A1 (lt) |
| AU (1) | AU2014219811B2 (lt) |
| BR (1) | BR112015019790B1 (lt) |
| CA (1) | CA2901585C (lt) |
| CL (1) | CL2015002311A1 (lt) |
| CY (1) | CY1119220T1 (lt) |
| DK (1) | DK2960238T3 (lt) |
| ES (1) | ES2628495T3 (lt) |
| HR (1) | HRP20170873T1 (lt) |
| HU (1) | HUE032931T2 (lt) |
| IL (1) | IL240623B (lt) |
| JO (1) | JO3261B1 (lt) |
| LT (1) | LT2960238T (lt) |
| ME (1) | ME02755B (lt) |
| MX (1) | MX361870B (lt) |
| MY (1) | MY178760A (lt) |
| NZ (1) | NZ711101A (lt) |
| PE (1) | PE20151509A1 (lt) |
| PH (1) | PH12015501813A1 (lt) |
| PL (1) | PL2960238T3 (lt) |
| PT (1) | PT2960238T (lt) |
| RS (1) | RS56064B1 (lt) |
| RU (1) | RU2645352C2 (lt) |
| SG (1) | SG11201506488WA (lt) |
| SI (1) | SI2960238T1 (lt) |
| SM (1) | SMT201700288T1 (lt) |
| TW (4) | TWI672139B (lt) |
| UA (1) | UA116794C2 (lt) |
| WO (1) | WO2014129477A1 (lt) |
| ZA (1) | ZA201505941B (lt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2914072T3 (es) * | 2014-08-18 | 2022-06-07 | Eisai R&D Man Co Ltd | Sal de derivado de piridina monocíclico y su cristal |
| JP6503450B2 (ja) * | 2015-03-25 | 2019-04-17 | 国立研究開発法人国立がん研究センター | 胆管癌治療剤 |
| MX384034B (es) * | 2015-12-17 | 2025-03-14 | Eisai R&D Man Co Ltd | Agente terapeutico para cancer de mama. |
| CN107098884A (zh) * | 2016-02-19 | 2017-08-29 | 中国科学院上海药物研究所 | 一类取代的氨基吡啶类化合物及其制备和用途 |
| SG11202001481PA (en) * | 2017-10-12 | 2020-03-30 | Eisai R&D Man Co Ltd | Pharmaceutical composition comprising fgfr selective tyrosine kinase inhibitor |
| BR112020017922A2 (pt) | 2018-03-28 | 2020-12-22 | Eisai R&D Management Co., Ltd. | Agente terapêutico para carcinoma hepatocelular |
| JP2022526713A (ja) | 2019-03-21 | 2022-05-26 | オンクセオ | がんの処置のための、キナーゼ阻害剤と組み合わせたＤｂａｉｔ分子 |
| JP2023500906A (ja) | 2019-11-08 | 2023-01-11 | インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） | キナーゼ阻害剤に対する獲得抵抗性を有するがんの処置方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| MX2022012934A (es) * | 2020-04-17 | 2022-11-08 | Eisai R&D Man Co Ltd | Agente terapeutico para cancer de mama. |
| CA3185174A1 (en) * | 2020-07-31 | 2022-02-03 | Eisai R&D Management Co., Ltd. | Therapeutic agent for breast cancer |
| JPWO2022092085A1 (lt) | 2020-10-28 | 2022-05-05 | ||
| TW202328099A (zh) | 2021-08-31 | 2023-07-16 | 日商衛材R&D企管股份有限公司 | 單環吡啶衍生物之製造方法 |
| CA3227445A1 (en) | 2021-08-31 | 2023-03-09 | Eisai R&D Management Co., Ltd. | Production method for synthetic intermediate of monocyclic pyridine derivative |
| AU2023236231A1 (en) * | 2022-03-18 | 2024-09-05 | Shanghai Institute Of Materia Medica , Chinese Academy Of Sciences | Salt of substituted amino six-membered nitric heterocyclic compound, crystal form thereof, method for preparing same, and use thereof |
| CN120021412A (zh) * | 2023-09-18 | 2025-05-20 | 上海润石医药科技有限公司 | 包含杂芳基氧基萘类化合物的药物组合物及其制备方法和应用 |
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| DE10006139A1 (de) * | 2000-02-11 | 2001-08-16 | Merck Patent Gmbh | Indol-3-yl-Derivate |
| DE60134679D1 (de) | 2000-10-20 | 2008-08-14 | Eisai R&D Man Co Ltd | Stickstoff enthaltende aromatische Heterozyklen |
| US6949585B2 (en) | 2001-04-03 | 2005-09-27 | Eisai Co., Ltd. | Cyclooctanone derivatives and cyclodecanone derivative, and use thereof |
| US20030187026A1 (en) * | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| KR100732440B1 (ko) * | 2002-08-30 | 2007-06-27 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 질소 함유 방향환 유도체 |
| US7098332B2 (en) | 2002-12-20 | 2006-08-29 | Hoffmann-La Roche Inc. | 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones |
| KR20050111636A (ko) | 2003-04-10 | 2005-11-25 | 에프. 호프만-라 로슈 아게 | 피리미도 화합물 |
| US20050256154A1 (en) | 2004-05-04 | 2005-11-17 | Kin-Chun Luk | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides |
| GB0512324D0 (en) | 2005-06-16 | 2005-07-27 | Novartis Ag | Organic compounds |
| FR2883286B1 (fr) | 2005-03-16 | 2008-10-03 | Sanofi Aventis Sa | NOUVEAUX DERIVES D'IMIDAZO[1,5-a]PYRIDINES, INHIBITEURS DE FGFs, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT |
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| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
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| US7737149B2 (en) | 2006-12-21 | 2010-06-15 | Astrazeneca Ab | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof |
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| EP2158471A1 (en) | 2007-06-25 | 2010-03-03 | Qinetiq Limited | Heater suitable for use in a preconcentrator device |
| WO2009019518A1 (en) | 2007-08-09 | 2009-02-12 | Astrazeneca Ab | Pyrimidine compounds having a fgfr inhibitory effect |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| WO2009056886A1 (en) | 2007-11-01 | 2009-05-07 | Astrazeneca Ab | Pyrimidine derivatives and their use as modulators of fgfr activity |
| CL2008003675A1 (es) * | 2007-12-13 | 2009-03-20 | Wyeth Corp | Compuestos derivados de 5-alquil o alquenil 3-cianopiridinas, procedimiento de preparacion, composicion farmaceutica, util para reducir la actividad incrementada de una enzima en un mamifero, en donde dicha enzima es una proteina quinasa, destinado al tratamiento de la inflamacion, asma, colitis, esclerosis multiple, soriasis, artritis reumatoide. |
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| AU2009248774B2 (en) | 2008-05-23 | 2012-05-31 | Novartis Ag | Derivatives of quinolines and quinoxalines as protein tyrosine kinase inhibitors |
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| BRPI0914233A2 (pt) | 2008-06-19 | 2015-11-03 | Astrazeneca Ab | composto, uso de um composto, métodos para produzir um efeito inibidor de fgfr e para produzir um efeito anticâncer em um animal de sangue quente, composição farmacêutica, e, método para tratar uma doença |
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| EP2270043A1 (en) | 2009-07-03 | 2011-01-05 | Sanofi-Aventis | Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor |
| PH12012500252A1 (en) | 2009-08-07 | 2015-06-26 | Chugai Pharmaceutical Co Ltd | Aminopyrazole derivative |
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-
2014
- 2014-02-17 AR ARP140100495A patent/AR094812A1/es active IP Right Grant
- 2014-02-18 JP JP2014526292A patent/JP5600229B1/ja active Active
- 2014-02-18 EP EP14754294.8A patent/EP2960238B1/en active Active
- 2014-02-18 WO PCT/JP2014/053819 patent/WO2014129477A1/ja not_active Ceased
- 2014-02-18 ES ES14754294.8T patent/ES2628495T3/es active Active
- 2014-02-18 RS RS20170596A patent/RS56064B1/sr unknown
- 2014-02-18 SI SI201430247A patent/SI2960238T1/sl unknown
- 2014-02-18 RU RU2015134558A patent/RU2645352C2/ru active
- 2014-02-18 ME MEP-2017-130A patent/ME02755B/me unknown
- 2014-02-18 SM SM20170288T patent/SMT201700288T1/it unknown
- 2014-02-18 NZ NZ711101A patent/NZ711101A/en unknown
- 2014-02-18 PE PE2015001748A patent/PE20151509A1/es active IP Right Grant
- 2014-02-18 LT LTEP14754294.8T patent/LT2960238T/lt unknown
- 2014-02-18 MX MX2015010698A patent/MX361870B/es active IP Right Grant
- 2014-02-18 TW TW107134526A patent/TWI672139B/zh active
- 2014-02-18 PL PL14754294T patent/PL2960238T3/pl unknown
- 2014-02-18 TW TW103105419A patent/TWI641602B/zh active
- 2014-02-18 CA CA2901585A patent/CA2901585C/en active Active
- 2014-02-18 PT PT147542948T patent/PT2960238T/pt unknown
- 2014-02-18 KR KR1020157022252A patent/KR102050128B1/ko active Active
- 2014-02-18 UA UAA201508149A patent/UA116794C2/uk unknown
- 2014-02-18 DK DK14754294.8T patent/DK2960238T3/en active
- 2014-02-18 JO JOP/2014/0039A patent/JO3261B1/ar active
- 2014-02-18 MY MYPI2015702696A patent/MY178760A/en unknown
- 2014-02-18 SG SG11201506488WA patent/SG11201506488WA/en unknown
- 2014-02-18 BR BR112015019790-6A patent/BR112015019790B1/pt active IP Right Grant
- 2014-02-18 HR HRP20170873TT patent/HRP20170873T1/hr unknown
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- 2014-02-18 CN CN201480009370.XA patent/CN105073730B/zh active Active
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- 2014-02-18 AU AU2014219811A patent/AU2014219811B2/en active Active
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- 2014-02-19 US US14/183,864 patent/US8933099B2/en active Active
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