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IT1197644B - Azepinoindoli,loro preparazione e loro impiego come medicamenti - Google Patents

Azepinoindoli,loro preparazione e loro impiego come medicamenti

Info

Publication number
IT1197644B
IT1197644B IT48232/83A IT4823283A IT1197644B IT 1197644 B IT1197644 B IT 1197644B IT 48232/83 A IT48232/83 A IT 48232/83A IT 4823283 A IT4823283 A IT 4823283A IT 1197644 B IT1197644 B IT 1197644B
Authority
IT
Italy
Prior art keywords
azepinoindoli
medications
preparation
Prior art date
Application number
IT48232/83A
Other languages
English (en)
Italian (it)
Other versions
IT8348232A1 (it
IT8348232A0 (it
Inventor
Fulvio Gadient
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8348232A0 publication Critical patent/IT8348232A0/it
Publication of IT8348232A1 publication Critical patent/IT8348232A1/it
Application granted granted Critical
Publication of IT1197644B publication Critical patent/IT1197644B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT48232/83A 1982-05-06 1983-05-06 Azepinoindoli,loro preparazione e loro impiego come medicamenti IT1197644B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2806/82A CH649553A5 (de) 1982-05-06 1982-05-06 Azepinoindole und verfahren zu deren herstellung.

Publications (3)

Publication Number Publication Date
IT8348232A0 IT8348232A0 (it) 1983-05-06
IT8348232A1 IT8348232A1 (it) 1984-11-06
IT1197644B true IT1197644B (it) 1988-12-06

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48232/83A IT1197644B (it) 1982-05-06 1983-05-06 Azepinoindoli,loro preparazione e loro impiego come medicamenti

Country Status (17)

Country Link
JP (1) JPS58203993A (es)
AU (1) AU1425683A (es)
BE (1) BE896590A (es)
CH (1) CH649553A5 (es)
DE (1) DE3315467A1 (es)
DK (1) DK199883A (es)
ES (1) ES8502440A1 (es)
FI (1) FI831475L (es)
FR (1) FR2526434A1 (es)
GB (1) GB2120662B (es)
HU (1) HU189275B (es)
IL (1) IL68576A0 (es)
IT (1) IT1197644B (es)
NL (1) NL8301552A (es)
PT (1) PT76632B (es)
SE (1) SE8302554L (es)
ZA (1) ZA833266B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8500370A (nl) * 1984-02-22 1985-09-16 Sandoz Ag Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
JP2004509894A (ja) * 2000-09-20 2004-04-02 ファルマシア・アンド・アップジョン・カンパニー 置換アゼピノ［４，５−ｂ］インドリン誘導体
CA2453537A1 (en) * 2001-08-08 2003-02-20 Pharmacia & Upjohn Company Therapeutic 1h-pyrido¬4,3-b|indoles
RU2434872C2 (ru) * 2006-01-19 2011-11-27 Атерсис, Инк. Тиофенильные и пирролильные азепины в качестве лигандов серотонинового 5-ht2c рецептора и их применение
BRPI0907122B8 (pt) 2008-01-11 2021-05-25 Albany Molecular Res Inc compostos de piridoindóis (1-azinona) substituídos, composição farmacêutica compreendendo os referidos compostos, e usos dos mesmos
US8637501B2 (en) 2009-07-01 2014-01-28 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
US8618299B2 (en) 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12641T1 (de) * 1979-11-02 1985-04-15 Sandoz Ag Azepinindole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
GB2120662B (en) 1985-09-11
GB2120662A (en) 1983-12-07
ZA833266B (en) 1984-12-24
CH649553A5 (de) 1985-05-31
NL8301552A (nl) 1983-12-01
JPS58203993A (ja) 1983-11-28
DK199883A (da) 1983-11-07
FI831475A7 (fi) 1983-11-07
PT76632A (en) 1983-06-01
SE8302554L (sv) 1983-11-07
DK199883D0 (da) 1983-05-04
FI831475A0 (fi) 1983-04-29
BE896590A (fr) 1983-10-28
HU189275B (en) 1986-06-30
DE3315467A1 (de) 1983-11-17
PT76632B (en) 1986-01-27
ES522008A0 (es) 1985-01-01
IT8348232A1 (it) 1984-11-06
GB8312159D0 (en) 1983-06-08
AU1425683A (en) 1983-11-10
ES8502440A1 (es) 1985-01-01
IL68576A0 (en) 1983-09-30
FR2526434A1 (fr) 1983-11-10
FI831475L (fi) 1983-11-07
SE8302554D0 (sv) 1983-05-04
IT8348232A0 (it) 1983-05-06

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