GB2120662B - New azepinoindoles their production and pharmaceutical compositions containing them - Google Patents

New azepinoindoles their production and pharmaceutical compositions containing them

Info

Publication number: GB2120662B
Authority: GB; United Kingdom
Prior art keywords: azepinoindoles; new; production; pharmaceutical compositions; compositions containing
Prior art date: 1982-05-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB08312159A

Other versions

GB2120662A (en

GB8312159D0 (en

Inventor

Fulvio Gadient

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-06

Filing date

1983-05-04

Publication date

1985-09-11

1983-05-04 Application filed by Sandoz AG filed Critical Sandoz AG

1983-06-08 Publication of GB8312159D0 publication Critical patent/GB8312159D0/en

1983-12-07 Publication of GB2120662A publication Critical patent/GB2120662A/en

1985-09-11 Application granted granted Critical

1985-09-11 Publication of GB2120662B publication Critical patent/GB2120662B/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

GB08312159A 1982-05-06 1983-05-04 New azepinoindoles their production and pharmaceutical compositions containing them Expired GB2120662B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH2806/82A CH649553A5 (en)	1982-05-06	1982-05-06	AZEPINOINDOLS AND METHOD FOR THE PRODUCTION THEREOF.

Publications (3)

Publication Number	Publication Date
GB8312159D0 GB8312159D0 (en)	1983-06-08
GB2120662A GB2120662A (en)	1983-12-07
GB2120662B true GB2120662B (en)	1985-09-11

Family

ID=4242007

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB08312159A Expired GB2120662B (en)	1982-05-06	1983-05-04	New azepinoindoles their production and pharmaceutical compositions containing them

Country Status (17)

Country	Link
JP (1)	JPS58203993A (en)
AU (1)	AU1425683A (en)
BE (1)	BE896590A (en)
CH (1)	CH649553A5 (en)
DE (1)	DE3315467A1 (en)
DK (1)	DK199883A (en)
ES (1)	ES522008A0 (en)
FI (1)	FI831475L (en)
FR (1)	FR2526434A1 (en)
GB (1)	GB2120662B (en)
HU (1)	HU189275B (en)
IL (1)	IL68576A0 (en)
IT (1)	IT1197644B (en)
NL (1)	NL8301552A (en)
PT (1)	PT76632B (en)
SE (1)	SE8302554L (en)
ZA (1)	ZA833266B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8500370A (en) *	1984-02-22	1985-09-16	Sandoz Ag	DIAZEPINOINDOLS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
AU582564B2 (en) *	1985-02-20	1989-04-06	Sandoz Ltd.	2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
PE20020510A1 (en)	2000-09-20	2002-06-12	Upjohn Co	DERIVATIVES OF AZEPYL [4,5b] INDOLINE SUBSTITUTE AS LIGANDS OF SEROTONIN (5-HT) RECEPTORS
JP2005526691A (en) *	2001-08-08	2005-09-08	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	Therapeutic agent 1H-pyrido [4,3-b] indole
AU2007207508B2 (en) *	2006-01-19	2011-08-18	Athersys, Inc.	Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof
JP5501251B2 (en)	2008-01-11	2014-05-21	アルバニーモレキュラーリサーチ，インコーポレイテッド	(1-Azinone) substituted pyridoindoles as MCH antagonists
WO2011003007A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
EP2448585B1 (en)	2009-07-01	2014-01-01	Albany Molecular Research, Inc.	Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2012088038A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof
US8993765B2 (en)	2010-12-21	2015-03-31	Albany Molecular Research, Inc.	Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE12641T1 (en) *	1979-11-02	1985-04-15	Sandoz Ag	AZEPININDOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

1982
- 1982-05-06 CH CH2806/82A patent/CH649553A5/en not_active IP Right Cessation
1983
- 1983-04-27 FR FR8307089A patent/FR2526434A1/en active Pending
- 1983-04-28 BE BE1/10774A patent/BE896590A/en not_active IP Right Cessation
- 1983-04-28 DE DE19833315467 patent/DE3315467A1/en not_active Withdrawn
- 1983-04-29 FI FI831475A patent/FI831475L/en not_active Application Discontinuation
- 1983-05-02 ES ES522008A patent/ES522008A0/en active Granted
- 1983-05-03 NL NL8301552A patent/NL8301552A/en not_active Application Discontinuation
- 1983-05-04 DK DK199883A patent/DK199883A/en not_active Application Discontinuation
- 1983-05-04 HU HU831531A patent/HU189275B/en unknown
- 1983-05-04 GB GB08312159A patent/GB2120662B/en not_active Expired
- 1983-05-04 IL IL68576A patent/IL68576A0/en unknown
- 1983-05-04 PT PT76632A patent/PT76632B/en unknown
- 1983-05-04 SE SE8302554A patent/SE8302554L/en not_active Application Discontinuation
- 1983-05-04 JP JP58078869A patent/JPS58203993A/en active Pending
- 1983-05-05 AU AU14256/83A patent/AU1425683A/en not_active Abandoned
- 1983-05-06 IT IT48232/83A patent/IT1197644B/en active
- 1983-05-06 ZA ZA833266A patent/ZA833266B/en unknown

Also Published As

Publication number	Publication date
IT1197644B (en)	1988-12-06
AU1425683A (en)	1983-11-10
BE896590A (en)	1983-10-28
DK199883A (en)	1983-11-07
FI831475A7 (en)	1983-11-07
GB2120662A (en)	1983-12-07
FI831475L (en)	1983-11-07
IT8348232A1 (en)	1984-11-06
FR2526434A1 (en)	1983-11-10
ES8502440A1 (en)	1985-01-01
DE3315467A1 (en)	1983-11-17
DK199883D0 (en)	1983-05-04
IT8348232A0 (en)	1983-05-06
ES522008A0 (en)	1985-01-01
GB8312159D0 (en)	1983-06-08
JPS58203993A (en)	1983-11-28
NL8301552A (en)	1983-12-01
IL68576A0 (en)	1983-09-30
SE8302554L (en)	1983-11-07
HU189275B (en)	1986-06-30
PT76632B (en)	1986-01-27
ZA833266B (en)	1984-12-24
PT76632A (en)	1983-06-01
SE8302554D0 (en)	1983-05-04
CH649553A5 (en)	1985-05-31
FI831475A0 (en)	1983-04-29

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Legal Events

Date	Code	Title	Description
1987-12-16	PCNP	Patent ceased through non-payment of renewal fee