[go: up one dir, main page]

IS4446A - Andestrogen benzothiophenyl efnasambönd - Google Patents

Andestrogen benzothiophenyl efnasambönd

Info

Publication number
IS4446A
IS4446A IS4446A IS4446A IS4446A IS 4446 A IS4446 A IS 4446A IS 4446 A IS4446 A IS 4446A IS 4446 A IS4446 A IS 4446A IS 4446 A IS4446 A IS 4446A
Authority
IS
Iceland
Prior art keywords
androgenic
benzothiophenyl
compounds
benzothiophenyl compounds
androgenic benzothiophenyl
Prior art date
Application number
IS4446A
Other languages
English (en)
Other versions
IS1788B (is
Inventor
Smith Labell Elisabeth
Douglas Luke Wayne
Mcneill Mcgill John
Scot Miller Randal
Original Assignee
Eli Lilly And Company, Patent Division
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26976194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS4446(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/308,325 external-priority patent/US5629425A/en
Application filed by Eli Lilly And Company, Patent Division filed Critical Eli Lilly And Company, Patent Division
Publication of IS4446A publication Critical patent/IS4446A/is
Publication of IS1788B publication Critical patent/IS1788B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS4446A 1994-09-19 1997-03-18 Andestrogen benzothiophenyl efnasambönd IS1788B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/308,325 US5629425A (en) 1994-09-19 1994-09-19 Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
US42791495A 1995-04-26 1995-04-26
PCT/US1995/011872 WO1996009045A1 (en) 1994-09-19 1995-09-19 Antiestrogenic benzothiophenyl compounds

Publications (2)

Publication Number Publication Date
IS4446A true IS4446A (is) 1997-03-18
IS1788B IS1788B (is) 2001-11-28

Family

ID=26976194

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4446A IS1788B (is) 1994-09-19 1997-03-18 Andestrogen benzothiophenyl efnasambönd

Country Status (50)

Country Link
US (4) US5731327A (is)
JP (2) JPH08193081A (is)
KR (2) KR100367376B1 (is)
CN (2) CN1068324C (is)
AP (1) AP754A (is)
AT (2) AT407988B (is)
AU (3) AU692907B2 (is)
BE (2) BE1009625A3 (is)
BG (1) BG62793B1 (is)
BR (2) BR9504059A (is)
CA (2) CA2158400C (is)
CH (3) CH691594A5 (is)
CO (2) CO4410190A1 (is)
CZ (2) CZ292007B6 (is)
DE (3) DE19549755B4 (is)
DK (4) DK175897B1 (is)
EE (1) EE03386B1 (is)
EG (1) EG23763A (is)
ES (2) ES2129293B1 (is)
FI (2) FI112226B (is)
FR (2) FR2724655B1 (is)
GB (2) GB2293382B (is)
GE (1) GEP19991821B (is)
GR (2) GR1002709B (is)
HR (2) HRP950482B1 (is)
HU (2) HU225417B1 (is)
IE (2) IE80883B1 (is)
IL (3) IL115315A (is)
IS (1) IS1788B (is)
IT (2) IT1277602B1 (is)
LU (2) LU88660A1 (is)
LV (2) LV11178B (is)
MY (1) MY116371A (is)
NL (2) NL1001194C2 (is)
NO (2) NO308107B1 (is)
NZ (2) NZ280028A (is)
OA (1) OA10406A (is)
PE (2) PE14796A1 (is)
PL (2) PL187686B1 (is)
PT (2) PT101771B (is)
RO (2) RO115260B1 (is)
RS (2) RS49513B (is)
SE (2) SE509265C2 (is)
SI (2) SI9500293A (is)
SK (1) SK283502B6 (is)
TR (1) TR199501136A2 (is)
TW (1) TW412534B (is)
UA (2) UA42716C2 (is)
UY (1) UY24040A1 (is)
WO (1) WO1996009045A1 (is)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39049E1 (en) 1992-07-28 2006-03-28 Eli Lilly And Company Methods for inhibiting bone loss
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
USRE38968E1 (en) 1992-07-28 2006-02-07 Eli Lilly And Company Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride
US5478847A (en) 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
US6458811B1 (en) * 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
RO121117B1 (ro) * 1996-03-26 2006-12-29 Eli Lilly And Company Compoziţie farmaceutică conţinând derivaţi de benzotiofen şi utilizarea acesteia
ZA979723B (en) 1996-10-30 1999-07-29 Lilly Co Eli Methods of preventing breast cancer.
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
NZ515134A (en) 1999-05-04 2004-01-30 Strakan Ltd Androgen glycosides and androgenic activity thereof
AU2002230409A1 (en) * 2000-11-27 2002-06-03 Eli Lilly And Company Process for preparing 3-aryl-benzo(b)thiophenes
CA2477088A1 (en) 2002-02-22 2003-10-02 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
CA2499819A1 (en) * 2002-09-30 2004-04-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
US20060106010A1 (en) * 2003-05-27 2006-05-18 Black Larry J Methods for inhibiting bone loss
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004029784A1 (de) 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004030502A1 (de) 2004-06-24 2006-01-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
DE102004033670A1 (de) 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US20060074088A1 (en) 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
US7728134B2 (en) 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
US20060035903A1 (en) 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US7759485B2 (en) 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
EP1630163A1 (de) 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
UA91520C2 (en) 2004-09-29 2010-08-10 Баер Шеринг Фарма Акциенгезельшафт Thermodynamically stable form of tosylate
US20060068010A1 (en) * 2004-09-30 2006-03-30 Stephen Turner Method for improving the bioavailability of orally delivered therapeutics
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102004058337A1 (de) 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
US7439358B2 (en) 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
KR101452915B1 (ko) 2006-05-04 2014-10-21 베링거 인겔하임 인터내셔날 게엠베하 다형태
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
AR062927A1 (es) 2006-10-11 2008-12-17 Bayer Healthcare Ag 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada
GB2456096B (en) * 2006-10-17 2011-08-17 Cipla Ltd Crystalline form of benzothiophene compound and process for preparation thereof
US8258291B2 (en) * 2006-10-25 2012-09-04 Mamtek International Limited Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
DE102007032451B4 (de) 2007-07-12 2010-09-30 Icfs Gmbh Verfahren zur Herstellung von aromatischen Ketonen
WO2009015004A1 (en) * 2007-07-20 2009-01-29 King Pharmaceuticals Research And Development, Inc. Crystals of (2-amino-4,5,6,7-tetrahydrobenzo[b]thien-3-yl)(4-chlorophenyl)methanone
WO2009019205A1 (en) 2007-08-03 2009-02-12 Boehringer Ingelheim International Gmbh Crystalline form of a dihydropteridione derivative
EP2242483B1 (en) * 2007-12-21 2013-02-20 Synthon B.V. Raloxifene composition
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
WO2009150669A1 (en) * 2008-06-09 2009-12-17 Erregierre S.P.A. Process for controlling the growth of a raloxifene hydrochloride crystal
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
MX2011002558A (es) 2008-09-10 2011-04-26 Boehringer Ingelheim Int Terapia de combinacion para el tratamiento de diabetes y estados relacionados.
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en) 2008-12-23 2015-09-03 Boehringer Ingelheim International Gmbh Salt forms of organic compound
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EP2448562B1 (en) 2009-07-02 2013-11-06 Synthon B.V. Raloxifene composition
EP2314581B1 (en) 2009-10-23 2012-07-25 Hexal AG A process for preparing benzo[b]thiophene derivatives
KR20120107080A (ko) 2009-11-27 2012-09-28 베링거 인겔하임 인터내셔날 게엠베하 리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
WO2011099942A1 (en) 2010-02-09 2011-08-18 Silverstone Pharma New addition salts of raloxifene, process for the preparation thereof and use thereof in therapy
KR101927068B1 (ko) 2010-05-05 2018-12-10 베링거 인겔하임 인터내셔날 게엠베하 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
KR20220025926A (ko) 2010-06-24 2022-03-03 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
IT1403083B1 (it) * 2010-10-25 2013-10-04 Fidia Farmaceutici Nuova forma polimorfa di raloxifene cloridrato
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
CN103781788B (zh) 2011-07-15 2016-08-17 勃林格殷格翰国际有限公司 经取代的喹唑啉、其制备及其在药物组合物中的用途
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171166A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ZA201401636B (en) 2013-03-05 2014-11-26 Cipla Ltd Oxalic acid addition salts and/or solvates of a selective estrogen receptor modulator
US20150031699A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome
CN104496963A (zh) * 2014-12-02 2015-04-08 千辉药业（安徽）有限责任公司 一种盐酸雷洛昔芬的制备方法
MX390363B (es) 2016-06-10 2025-03-20 Boehringer Ingelheim Int Combinacion de linagliptina y metformina
KR102815172B1 (ko) * 2020-02-25 2025-05-29 엘지전자 주식회사 히트펌프 및 그 동작방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3869485A (en) * 1969-09-25 1975-03-04 Allied Chem Preparation of acid chlorides with phosgene in the presence of a catalyst
GB1456323A (en) * 1974-06-06 1976-11-24 Labaz Benzothiophenes process for preparing them and pharmaceutical compositions containing the same
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
IL65378A (en) 1981-04-03 1986-02-28 Lilly Co Eli Process for preparing 3-(4-aminoethoxybenzoyl)benzo-(b)thiophenes
US4358593A (en) 1981-04-03 1982-11-09 Eli Lilly And Company Process for preparing 3-(4-aminoethoxybenzoyl)benzo[b]thiophenes
US4380635A (en) 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
IL65379A0 (en) 1981-04-03 1982-05-31 Lilly Co Eli Process for preparing acylated benzothiophenes
AU555658B2 (en) 1981-04-03 1986-10-02 Eli Lilly And Company Benzothiophene compounds
ZA822247B (en) 1981-04-03 1983-11-30 Lilly Co Eli Benzothiophene compounds and process for preparing them
DE4117512A1 (de) 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
US5169860A (en) 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
TW383306B (en) * 1992-12-22 2000-03-01 Lilly Co Eli New use of 2-phenyl-3-aroylbenzothiophenes in lowering serum cholesterol
DE69405491T2 (de) 1993-06-24 1998-02-19 Lilly Co Eli Antiöstrogene 2-Phenyl-3-Aroylbenzothiophene als hypoglykämische Mittel
US6756388B1 (en) 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US5523416A (en) 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO

Also Published As

Publication number Publication date
FR2724655B1 (fr) 1997-11-14
HU9502723D0 (en) 1995-11-28
HRP950482A2 (en) 1998-02-28
IL115314A (en) 2000-02-29
DE19534744A1 (de) 1996-03-21
CN1068324C (zh) 2001-07-11
PE32796A1 (es) 1996-08-07
CA2158400C (en) 2006-10-24
CO4410191A1 (es) 1997-01-09
PT101771A (pt) 1996-04-30
SE9503214D0 (sv) 1995-09-15
NZ280028A (en) 1997-05-26
UA42716C2 (uk) 2001-11-15
AU692907B2 (en) 1998-06-18
YU61495A (sh) 1998-05-15
CH691478A5 (de) 2001-07-31
NL1001194A1 (nl) 1996-03-19
CN1127253A (zh) 1996-07-24
NL1001194C2 (nl) 1997-04-04
NO313996B1 (no) 2003-01-13
GB2293382B (en) 1998-08-19
GR1002709B (el) 1997-06-04
GB2293602B (en) 1998-05-06
LV11178A (lv) 1996-04-20
AP754A (en) 1999-07-22
US5731327A (en) 1998-03-24
CA2158399A1 (en) 1996-03-20
FR2724655A1 (fr) 1996-03-22
CA2158400A1 (en) 1996-03-20
HU227683B1 (en) 2011-11-28
ES2129293B1 (es) 2000-01-16
DK175903B1 (da) 2005-06-06
CO4410190A1 (es) 1997-01-09
ES2109882A1 (es) 1998-01-16
SE9503214L (sv) 1996-03-20
US6472531B1 (en) 2002-10-29
DK2797A (da) 1997-01-09
PL310517A1 (en) 1996-04-01
YU61395A (sh) 1998-09-18
HUT74178A (en) 1996-11-28
SE520721C2 (sv) 2003-08-12
IL115315A0 (en) 1995-12-31
AU691955B2 (en) 1998-05-28
IE80883B1 (en) 1999-05-19
FI954402A0 (fi) 1995-09-18
CZ290343B6 (cs) 2002-07-17
GB2293382A (en) 1996-03-27
DK102895A (da) 1996-03-20
CZ240295A3 (en) 1996-04-17
UA44240C2 (uk) 2002-02-15
ATA154295A (de) 2000-12-15
KR100367376B1 (ko) 2003-03-06
EG23763A (en) 2007-08-08
IS1788B (is) 2001-11-28
HRP950483B1 (en) 2003-02-28
BE1009625A3 (fr) 1997-06-03
UY24040A1 (es) 1996-03-07
NO953658L (no) 1996-03-20
LU88661A1 (fr) 1996-07-15
GEP19991821B (en) 1999-11-05
RS49578B (sr) 2007-04-10
LV11177B (en) 1996-08-20
JP2860071B2 (ja) 1999-02-24
MY116371A (en) 2004-01-31
SI9500292A (en) 1996-06-30
CN1132205A (zh) 1996-10-02
BR9504059A (pt) 1996-09-24
US20020173645A1 (en) 2002-11-21
SE9503213L (sv) 1996-03-20
PT101770B (pt) 1997-04-30
NO308107B1 (no) 2000-07-24
RS49513B (sr) 2006-10-27
EE9700055A (et) 1997-08-15
DK2897A (da) 1997-01-09
NO953657L (no) 1996-03-20
ITMI951936A1 (it) 1997-03-15
DK175886B1 (da) 2005-05-23
IT1277602B1 (it) 1997-11-11
FR2732020B1 (fr) 1997-11-14
JPH08193081A (ja) 1996-07-30
RO115259B1 (ro) 1999-12-30
CN1075069C (zh) 2001-11-21
IL125283A (en) 2001-06-14
HU225417B1 (en) 2006-11-28
BG62793B1 (bg) 2000-08-31
SE9503213D0 (sv) 1995-09-15
FI954402L (fi) 1996-03-20
HK1019009A1 (en) 2000-01-14
AT502957A1 (de) 2007-06-15
NO953657D0 (no) 1995-09-15
DK102795A (da) 1996-03-20
DK175897B1 (da) 2005-05-30
SK23397A3 (en) 1997-08-06
CZ240395A3 (en) 1996-04-17
KR960010634A (ko) 1996-04-20
EE03386B1 (et) 2001-04-16
GR1002697B (el) 1997-05-22
HUT75033A (en) 1997-03-28
PL187686B1 (pl) 2004-09-30
WO1996009045A1 (en) 1996-03-28
RO115260B1 (ro) 1999-12-30
FI112226B (fi) 2003-11-14
GB2293602A (en) 1996-04-03
PL310518A1 (en) 1996-04-01
IL115315A (en) 1999-09-22
ITMI951935A1 (it) 1997-03-15
AU3718695A (en) 1996-04-09
CA2158399C (en) 2001-03-20
BR9504060A (pt) 1996-09-24
AP9700938A0 (en) 1997-04-30
NO953658D0 (no) 1995-09-15
JPH08176147A (ja) 1996-07-09
DE19534745A1 (de) 1996-04-04
IT1277601B1 (it) 1997-11-11
FI954403A7 (fi) 1996-03-20
HU9502721D0 (en) 1995-11-28
AT407988B (de) 2001-07-25
SK283502B6 (sk) 2003-08-05
IE950722A1 (en) 1996-03-20
CH691594A5 (de) 2001-08-31
IE950721A1 (en) 1996-03-20
KR100381346B1 (ko) 2004-04-13
ITMI951936A0 (it) 1995-09-15
OA10406A (en) 2001-12-05
PT101771B (pt) 1997-04-30
NL1001196C2 (nl) 1997-04-04
AU3173195A (en) 1996-04-04
PE14796A1 (es) 1996-05-19
CZ292007B6 (cs) 2003-07-16
NL1001196A1 (nl) 1996-03-19
HRP950483A2 (en) 1997-10-31
LV11177A (lv) 1996-04-20
US6399778B1 (en) 2002-06-04
BE1009626A3 (fr) 1997-06-03
PT101770A (pt) 1996-04-30
ITMI951935A0 (it) 1995-09-15
FR2732020A1 (fr) 1996-09-27
DE19549755B4 (de) 2005-05-04
TW412534B (en) 2000-11-21
TR199501136A2 (tr) 1996-06-21
FI954403A0 (fi) 1995-09-18
BG101242A (en) 1998-03-31
CH691125A5 (de) 2001-04-30
KR960010637A (ko) 1996-04-20
GB9519028D0 (en) 1995-11-15
ES2109882B1 (es) 1998-08-16
GB9519032D0 (en) 1995-11-15
LU88660A1 (fr) 1996-07-15
LV11178B (en) 1996-08-20
SI9500293A (en) 1996-06-30
NZ280027A (en) 1997-05-26
DK175887B1 (da) 2005-05-23
PL182450B1 (pl) 2002-01-31
IL115314A0 (en) 1996-05-14
SE509265C2 (sv) 1998-12-21
AU3173095A (en) 1996-04-04
DE19534745B4 (de) 2004-06-09
ES2129293A1 (es) 1999-06-01
FI121424B (fi) 2010-11-15
HRP950482B1 (en) 2007-04-30

Similar Documents

Publication Publication Date Title
IS4446A (is) Andestrogen benzothiophenyl efnasambönd
DK0802183T3 (da) Østrogenforbindelser
DK0777671T3 (da) Spiro-azabicykliske forbindelser
FI971260A7 (fi) 1-asyyli-4-alifatyyliaminopiperidiiniyhdisteet
FI972970A0 (fi) Uusia yhdisteitä
NO971814D0 (no) Östrogene midler
BR9600534A (pt) Novos compostos
BR9710352A (pt) Compostos piridilpirrole
DE69716924D1 (de) Phosphonat-nukleotid-verbindungen
PT906288E (pt) Novos compostos
BR9705635A (pt) Compostos
FI950403L (fi) Neurosuojaavia yhdisteitä
FI970151A0 (fi) Viruksenvastaisesti vaikuttavia difluoristatoniyhdisteitä
DE69709659D1 (de) Halopropargyl-einschlussverbindungen
BR9509740A (pt) Compostos 18-nor-vitamina d
IS4932A (is) Ný efnasambönd
FI971971A7 (fi) Pyridatsinokinoliiniyhdisteitä
KR950024252U (ko) 부착이 용이한 단추
SE9402170D0 (sv) New compounds
SE9402813D0 (sv) New compounds
SE9402838D0 (sv) New compounds
SE9403728D0 (sv) New compounds
SE9603470D0 (sv) New compounds
SE9600555D0 (sv) New compounds
SE9600554D0 (sv) New compounds