[go: up one dir, main page]

IL135299A0 - Automatable method for preparing samples which can be universally applied - Google Patents

Automatable method for preparing samples which can be universally applied

Info

Publication number
IL135299A0
IL135299A0 IL13529998A IL13529998A IL135299A0 IL 135299 A0 IL135299 A0 IL 135299A0 IL 13529998 A IL13529998 A IL 13529998A IL 13529998 A IL13529998 A IL 13529998A IL 135299 A0 IL135299 A0 IL 135299A0
Authority
IL
Israel
Prior art keywords
sample
incubating
metal oxide
glass particles
preparing samples
Prior art date
Application number
IL13529998A
Other languages
English (en)
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of IL135299A0 publication Critical patent/IL135299A0/xx

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/032Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials
    • H01F1/10Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure
    • H01F1/11Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure in the form of particles
    • H01F1/112Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure in the form of particles with a skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • CCHEMISTRY; METALLURGY
    • C03GLASS; MINERAL OR SLAG WOOL
    • C03CCHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C14/00Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix
    • C03C14/004Glass compositions containing a non-glass component, e.g. compositions containing fibres, filaments, whiskers, platelets, or the like, dispersed in a glass matrix the non-glass component being in the form of particles or flakes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • C07H1/08Separation; Purification from natural products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Power Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Materials Engineering (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Robotics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL13529998A 1997-10-01 1998-09-29 Automatable method for preparing samples which can be universally applied IL135299A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19743518A DE19743518A1 (de) 1997-10-01 1997-10-01 Automatisierbare universell anwendbare Probenvorbereitungsmethode
PCT/EP1998/006196 WO1999016781A2 (de) 1997-10-01 1998-09-29 Automatisierbare universell anwendbare probenvorbereitungsmethode

Publications (1)

Publication Number Publication Date
IL135299A0 true IL135299A0 (en) 2001-05-20

Family

ID=7844362

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13529998A IL135299A0 (en) 1997-10-01 1998-09-29 Automatable method for preparing samples which can be universally applied
IL135299A IL135299A (en) 1997-10-01 2000-03-27 Process and kit for the isolation of a nucleic acid analyte from a biological sample

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL135299A IL135299A (en) 1997-10-01 2000-03-27 Process and kit for the isolation of a nucleic acid analyte from a biological sample

Country Status (13)

Country Link
US (2) US6562568B1 (xx)
EP (2) EP1019430B1 (xx)
JP (3) JP4048022B2 (xx)
KR (1) KR20010024366A (xx)
AT (1) ATE366739T1 (xx)
AU (1) AU1028299A (xx)
CA (1) CA2305171C (xx)
DE (2) DE19743518A1 (xx)
DK (1) DK1019430T3 (xx)
ES (2) ES2290996T3 (xx)
IL (2) IL135299A0 (xx)
PT (1) PT1019430E (xx)
WO (1) WO1999016781A2 (xx)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
DE19520398B4 (de) 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
WO1999029703A2 (en) * 1997-12-06 1999-06-17 Dna Research Instruments Limited Isolation of nucleic acids
EP1147226B1 (en) * 1999-01-27 2013-01-23 Folim G. Halaka Materials and methods for the purification of polyelectrolytes
DE19937607A1 (de) * 1999-08-09 2001-02-15 Bilatec Ges Zur Entwicklung Bi Reagenzienkit zur Isolierung von Nukleinsäuren
CZ20021608A3 (cs) * 1999-11-17 2003-06-18 Roche Diagnostics Gmbh Magnetické skleněné částice, metody jejich přípravy a použití
JP2004515219A (ja) * 2000-06-15 2004-05-27 ボード・オブ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム 調節可能な触媒活性な核酸
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
DE10127068A1 (de) * 2001-05-23 2002-11-28 Bio Medical Apherese Systeme G Vorrichtung und Verfahren zum Inkubieren und Wiederabtrennen von Magnetteilchen in und von flüssige biologische Dispersionen
DE10147439B4 (de) * 2001-09-26 2014-01-30 Qiagen Gmbh Verfahren zur Isolierung von DNA aus biologischen Proben
DE60316660T3 (de) 2002-01-08 2016-01-28 Roche Diagnostics Gmbh Verwendung eines silikamaterials bei der amplifikation
CA2473376A1 (en) 2002-01-16 2003-07-31 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
US20040234898A1 (en) * 2002-02-06 2004-11-25 Batishko Charles R. Magnetic flowcell systems and methods
JP2005533862A (ja) 2002-07-25 2005-11-10 アーケミックス コーポレイション 調節されたアプタマー治療剤
US9394332B2 (en) 2002-08-29 2016-07-19 Epigenomics Ag Method for bisulfite treatment
DE602004009038T3 (de) 2003-01-29 2015-06-25 Roche Diagnostics Gmbh Verbessertes Verfahren zur Behandlung durch Bisulfit
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
JP3644641B2 (ja) * 2003-03-07 2005-05-11 株式会社日立ハイテクノロジーズ 核酸回収方法
CN1878866B (zh) 2003-07-25 2012-08-01 安比恩股份有限公司 用于从固定的样品中制备rna的方法和组合物
US20050042660A1 (en) * 2003-07-31 2005-02-24 Hall Gerald Edward Devices and methods for isolating RNA
GB0319671D0 (en) * 2003-08-21 2003-09-24 Secr Defence Apparatus for processing a fluid sample
CA2482097C (en) 2003-10-13 2012-02-21 F. Hoffmann-La Roche Ag Methods for isolating nucleic acids
CA2547743C (en) 2003-12-02 2011-06-28 F. Hoffmann-La Roche Ag Improved method for bisulfite treatment
WO2005068662A1 (en) * 2003-12-30 2005-07-28 Sigma-Aldrich Co. Rapid preparation of nucleic acids by enzymatic digestion
ATE485401T1 (de) 2004-02-10 2010-11-15 Hoffmann La Roche Neue primer und sonden zum nachweis von parvovirus b19
US9267167B2 (en) * 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
US20060099605A1 (en) * 2004-11-11 2006-05-11 Hall Gerald E Jr Devices and methods for isolating RNA
EP1632578A1 (en) 2004-09-03 2006-03-08 Roche Diagnostics GmbH DNA decontamination method
EP1690938A1 (de) * 2005-02-11 2006-08-16 Qiagen GmbH Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden
US20060269929A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods and kits for DNA purification on polymeric membranes at low ionic strength
US20060270843A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods for isolation of nucleic acids
JP4733456B2 (ja) * 2005-07-26 2011-07-27 シスメックス株式会社 前処理の外部精度管理方法、核酸検出処理の外部精度管理方法、検量線作成処理の外部精度管理方法、前処理の外部精度管理コンピュータ、核酸検出処理の外部精度管理コンピュータ、検量線作成処理の外部精度管理コンピュータ、前処理装置、及び核酸検出装置
GB0525231D0 (en) * 2005-12-12 2006-01-18 Genpoint As Method
US7981606B2 (en) 2005-12-21 2011-07-19 Roche Molecular Systems, Inc. Control for nucleic acid testing
FR2895993A1 (fr) * 2006-01-10 2007-07-13 Immunid Sarl Composition pour la stabilisation d'echantillons biologiques et procede de stabilisation
EP1977242B1 (en) * 2006-01-27 2016-08-03 Becton Dickinson and Company Lateral flow immunoassay with encapsulated detection modality
WO2008057375A2 (en) 2006-11-03 2008-05-15 Siemens Healthcare Diagnostics Inc. Random access system and method for polymerase chain reaction testing
CA2614069C (en) 2006-12-11 2016-05-03 F. Hoffmann-La Roche Ag Nucleic acid isolation using polidocanol and derivatives
WO2008071384A1 (en) 2006-12-13 2008-06-19 Roche Diagnostics Gmbh Use of tde for the isolation of nucleic acids
EP2126074B1 (en) 2006-12-13 2010-12-01 Roche Diagnostics GmbH Use of acetals for the isolation of nucleic acids
US8535888B2 (en) 2006-12-29 2013-09-17 Mayo Foundation For Medical Education And Research Compositions and methods for detecting methicillin-resistant S. aureus
US8703492B2 (en) 2007-04-06 2014-04-22 Qiagen Gaithersburg, Inc. Open platform hybrid manual-automated sample processing system
US7985375B2 (en) * 2007-04-06 2011-07-26 Qiagen Gaithersburg, Inc. Sample preparation system and method for processing clinical specimens
DE102008010693A1 (de) * 2008-02-22 2009-08-27 Qiagen Gmbh Neue Matrixmaterialien, Verfahren zu ihrer Herstellung und ihre Verwendung in Verfahren zur Isolierung von Biomolekülen
JP5572939B2 (ja) * 2008-10-27 2014-08-20 株式会社島津製作所 Dnaの塩基配列決定法
US8911663B2 (en) 2009-03-05 2014-12-16 Quebec Metal Powders, Ltd. Insulated iron-base powder for soft magnetic applications
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
US9953141B2 (en) 2009-11-18 2018-04-24 Becton, Dickinson And Company Laboratory central control unit method and system
US9175332B2 (en) 2010-07-29 2015-11-03 Roche Molecular Systems, Inc. Generic PCR
JP6348202B2 (ja) * 2010-07-29 2018-06-27 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 一般的な試料調製
CA2802563C (en) 2010-07-29 2018-08-28 F. Hoffmann-La Roche Ag Preparation of nucleic acids from different types of biological fluid samples
US9725754B2 (en) 2010-07-29 2017-08-08 Sean F. Boyle Generic sample preparation
US8609340B2 (en) 2010-07-29 2013-12-17 Roche Molecular Systems, Inc. Control nucleic acids for multiple parameters
CA2835641C (en) * 2011-05-11 2019-05-28 Exosome Diagnostics, Inc. Nucleic acid extraction from heterogeneous biological materials
US9734946B2 (en) 2011-11-09 2017-08-15 The Regents Of The University Of California Superparamagnetic colloids with enhanced charge stability for high quality magnetically tunable photonic structures
EP2664914A1 (en) * 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetically assisted processing of a medium
US9399986B2 (en) 2012-07-31 2016-07-26 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
CA2889415C (en) 2012-10-24 2020-06-02 Genmark Diagnostics, Inc. Integrated multiplex target analysis
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US9222623B2 (en) 2013-03-15 2015-12-29 Genmark Diagnostics, Inc. Devices and methods for manipulating deformable fluid vessels
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
JP5928435B2 (ja) 2013-11-01 2016-06-01 株式会社安川電機 ロボットシステム、検査方法および被検査物の生産方法
CN105255855A (zh) * 2014-07-10 2016-01-20 上海艾迪康医学检验所有限公司 在固体表面保存核酸的方法及其保存液
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
CN107257857B (zh) 2014-11-14 2021-12-14 康宁股份有限公司 用于ivt后rna纯化的方法和试剂盒
EP3434372B1 (en) * 2014-11-19 2020-02-26 F. Hoffmann-La Roche AG Particle mixing
EP3397972A2 (en) 2015-12-31 2018-11-07 Universal Diagnostics, S.L. Systems and methods for automated, customizable sample preparation tool, software script, and calibration routine for detection of metabolites and lipids
ES2785607T3 (es) * 2016-01-05 2020-10-07 Hoffmann La Roche Captura sucesiva de ácido nucleico mediante partículas de vidrio magnético
WO2018046748A1 (en) * 2016-09-12 2018-03-15 Roche Diagnostics Gmbh Methods and compositions for purifying double stranded nucleic acids
WO2019014486A1 (en) 2017-07-12 2019-01-17 Exosome Diagnostics, Inc. METHODS FOR ISOLATING AND ENRICHING POPULATIONS OF EXTRACELLULAR VESICLES DERIVED FROM BIOFLUIDS, AND METHODS OF USE THEREOF
CN114381368B (zh) * 2021-12-31 2023-10-27 北京理工大学 一种利用气液界面自动分离生物分析物的系统及方法

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913419A (en) * 1956-04-18 1959-11-17 Du Pont Chemical process and composition
US2885366A (en) * 1956-06-28 1959-05-05 Du Pont Product comprising a skin of dense, hydrated amorphous silica bound upon a core of another solid material and process of making same
DE2313331C2 (de) * 1973-03-17 1986-11-13 Merck Patent Gmbh, 6100 Darmstadt Eisenoxidhaltige Glimmerschuppenpigmente
US3945862A (en) * 1973-06-26 1976-03-23 Merck & Co., Inc. Coated ferrous substrates comprising an amorphous magnesia-silica complex
US4133169A (en) * 1974-08-30 1979-01-09 Ebauches S.A. Electronic circuit for a quartz crystal watch
DE2625106C2 (de) * 1976-06-04 1982-03-11 Bayer Ag, 5090 Leverkusen Eisenoxidschwarz-Pigmente mit verbesserter Oxidationsbeständigkeit und Verfahren zu ihrer Herstellung
US4124385A (en) * 1976-12-02 1978-11-07 Xerox Corporation Magnetic glass carrier materials
US4126437A (en) * 1976-12-02 1978-11-21 Xerox Corporation Magnetic glass carrier materials
US4124735A (en) * 1976-12-02 1978-11-07 Xerox Corporation Magnetic glass carrier materials
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4395271A (en) * 1979-04-13 1983-07-26 Corning Glass Works Method for making porous magnetic glass and crystal-containing structures
JPS5676510A (en) * 1979-11-28 1981-06-24 Tdk Corp Manufacture of magnetic recording material
JPS56105337A (en) * 1980-01-28 1981-08-21 Tdk Corp Magnetic recording medium and its production
US4280918A (en) * 1980-03-10 1981-07-28 International Business Machines Corporation Magnetic particle dispersions
US4360441A (en) * 1981-06-25 1982-11-23 Corning Glass Works Glass-encapsulated magnetic materials and methods for making them
US4454234A (en) * 1981-12-30 1984-06-12 Czerlinski George H Coated magnetizable microparticles, reversible suspensions thereof, and processes relating thereto
US4448884A (en) * 1982-03-03 1984-05-15 Kms Fusion, Inc. Glass-surface microcarrier for growth of cell cultures
US4477492A (en) * 1983-04-22 1984-10-16 E. I. Du Pont De Nemours And Company Process for preparing superficially porous supports for chromatography and catalysts
US4695392A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4628037A (en) * 1983-05-12 1986-12-09 Advanced Magnetics, Inc. Binding assays employing magnetic particles
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4698302A (en) * 1983-05-12 1987-10-06 Advanced Magnetics, Inc. Enzymatic reactions using magnetic particles
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
GB8401636D0 (en) * 1984-01-21 1984-02-22 British Petroleum Co Plc Coating process
US5236623A (en) * 1984-07-11 1993-08-17 Rhone-Poulenc Chimie Process for the production of a silica colloid
US4824712A (en) * 1984-07-16 1989-04-25 Ppg Industries, Inc. Treatment of glass to reduce venting during thermal treatment and a glass article made thereby
US4748121A (en) * 1984-11-30 1988-05-31 Ppg Industries, Inc. Porous glass fibers with immobilized biochemically active material
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5597531A (en) * 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US5512332A (en) * 1985-10-04 1996-04-30 Immunivest Corporation Process of making resuspendable coated magnetic particles
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
US5206568A (en) * 1986-03-26 1993-04-27 Beckman Instruments, Inc. Coordinated control of stepper motors
US4751211A (en) * 1986-08-07 1988-06-14 Aluminum Company Of America Composite adsorbent for removing acids from organophosphate functional fluids
JPS63109105A (ja) * 1986-10-25 1988-05-13 Chisso Corp 強磁性金属微粒子の製造方法
DE3639949A1 (de) * 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US4699171A (en) * 1986-12-19 1987-10-13 Sundstrand Corporation Multiple port relief valve
US4767670A (en) * 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
NO162946C (no) * 1987-08-21 1990-03-14 Otto Soerensen Anordning for magnetisk separasjon av celler.
CH672445A5 (xx) 1987-02-27 1989-11-30 Hratch Boyadjian
ES2054797T3 (es) * 1987-03-02 1994-08-16 Gen Probe Inc Soportes policationicos para purificar, separar e hibridar acidos nucleicos.
DE68920778T2 (de) * 1988-05-24 1995-05-18 Anagen Uk Ltd Magnetisch anziehbare Teilchen und Herstellungsverfahren.
US5312485A (en) * 1988-08-05 1994-05-17 J. M. Huber Corporation Precipitated encapsulated paper pigments and methods
US5041390A (en) * 1988-08-11 1991-08-20 Skov Per S Method and means for allergy diagnosis
US5075430A (en) * 1988-12-12 1991-12-24 Bio-Rad Laboratories, Inc. Process for the purification of DNA on diatomaceous earth
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5352645A (en) * 1989-04-14 1994-10-04 E. I. Du Pont De Nemours And Company Silica microspheres, method of improving attrition resistance and use
US5055194A (en) * 1989-07-28 1991-10-08 University Of Pennsylvania Support for high performance liquid chromatography in a magnetically stabilized fluidized bed
US5279936A (en) * 1989-12-22 1994-01-18 Syntex (U.S.A.) Inc. Method of separation employing magnetic particles and second medium
US5523231A (en) * 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
EP0443840B1 (en) * 1990-02-21 1995-04-19 Toda Kogyo Corp. Superparamagnetic fine particles of iron oxide and magnetic recording media containing said particles
US5316699A (en) * 1990-03-28 1994-05-31 The United States Of America As Repesented By The Secretary Of Commerce Process for the controlled preparation of a composite of ultrafine magnetic particles homogeneously dispersed in a dielectric matrix
ATE154981T1 (de) * 1990-04-06 1997-07-15 Perkin Elmer Corp Automatisiertes labor für molekularbiologie
US5763173A (en) * 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand inhibitors to DNA polymerases
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5217804A (en) * 1990-11-06 1993-06-08 Eastman Kodak Company Magnetic particles
US5155018A (en) * 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5395498A (en) * 1991-11-06 1995-03-07 Gombinsky; Moshe Method for separating biological macromolecules and means therfor
US5734020A (en) * 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5610274A (en) * 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
EP0566790B1 (en) * 1992-04-23 1996-08-07 Toda Kogyo Corp. Magnetic powder and magnetic toner
TW221381B (xx) * 1992-04-28 1994-03-01 Du Pont
IT1256064B (it) * 1992-07-28 1995-11-27 Donegani Guido Ist Metodo per la preparazione di geli porosi contenenti boro
CA2107524C (en) * 1992-10-06 1999-01-19 Hiromitsu Misawa Iron oxide particles and process for producing the same
US5578238A (en) * 1992-10-30 1996-11-26 Lord Corporation Magnetorheological materials utilizing surface-modified particles
CA2102264C (en) * 1992-11-13 2000-08-01 Daniel Lee Woodard Boron silicates, aluminum silicates, phosphosilicates and purification of dna
US5648170A (en) * 1993-04-27 1997-07-15 Toda Kogyo Corporation Coated granular magnetite particles and process for producing the same
WO1995006652A1 (en) * 1993-08-30 1995-03-09 Promega Corporation Nucleic acid purification compositions and methods
US5438127A (en) * 1993-09-27 1995-08-01 Becton Dickinson And Company DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane
US5503816A (en) * 1993-09-27 1996-04-02 Becton Dickinson And Company Silicate compounds for DNA purification
US5599627A (en) * 1993-10-08 1997-02-04 Toda Kogyo Corporation Magnetic particles comprising magnetite core and process for producing the same
US5538848A (en) * 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
AU693511B2 (en) * 1994-02-07 1998-07-02 Qiagen Gmbh Endotoxin reduction or removal process
US5990301A (en) * 1994-02-07 1999-11-23 Qiagen Gmbh Process for the separation and purification of nucleic acids from biological sources
GB9411572D0 (en) * 1994-06-09 1994-08-03 Amersham Int Plc Magnetic bead precipitation method
JP3436760B2 (ja) * 1994-07-27 2003-08-18 ハーバート ピルグリム 超常磁性粒子
US5705628A (en) * 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
US5660984A (en) * 1994-12-09 1997-08-26 Davis; Thomas E. DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof
FR2732116B1 (fr) * 1995-03-21 1997-05-09 Bio Merieux Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique
US5683875A (en) * 1995-05-04 1997-11-04 Hewlett-Packard Company Method for detecting a target nucleic acid analyte in a sample
IN188702B (xx) * 1995-06-01 2002-10-26 Degussa
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
DE19520964A1 (de) 1995-06-08 1996-12-12 Inst Neue Mat Gemein Gmbh Beschichtete anorganische Pigmente, Verfahren zu deren Herstellung und deren Verwendung
WO2000032762A1 (de) * 1998-11-30 2000-06-08 Roche Diagnostics Gmbh Magnetische partikel zur reinigung von nukleinsäuren
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
CA2231861A1 (en) 1995-09-13 1997-03-20 Takanori Oka Method for concentrating mutant nucleic acid and nucleic acid-concentrating assay kit for said concentration method
US5783686A (en) * 1995-09-15 1998-07-21 Beckman Instruments, Inc. Method for purifying nucleic acids from heterogenous mixtures
US5904848A (en) * 1996-02-21 1999-05-18 Cpg, Inc. Controlled pore glass-synthetic resin membrane
US5972721A (en) * 1996-03-14 1999-10-26 The United States Of America As Represented By The Secretary Of The Air Force Immunomagnetic assay system for clinical diagnosis and other purposes
DE19622885A1 (de) * 1996-06-07 1997-12-11 Boehringer Mannheim Gmbh Reagenzzubereitung enthaltend magnetische Partikel in Form einer Tablette
US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
KR100464870B1 (ko) 1997-01-21 2005-01-05 더블유.알. 그레이스 앤드 캄파니-콘. 자성 물질상의 실리카 흡착제
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6242235B1 (en) 1998-06-24 2001-06-05 Promega Corp. Polymerase stabilization by polyethoxylated amine surfactants
US7267964B2 (en) * 2000-03-31 2007-09-11 Merial Limited DNA molecules encoding ligand gated ion channels from Dermacentor variabilis

Also Published As

Publication number Publication date
JP4048022B2 (ja) 2008-02-13
EP1783135B1 (de) 2012-11-07
ES2290996T3 (es) 2008-02-16
WO1999016781A2 (de) 1999-04-08
IL135299A (en) 2010-11-30
PT1019430E (pt) 2007-10-16
KR20010024366A (ko) 2001-03-26
EP1019430A2 (de) 2000-07-19
JP2001518284A (ja) 2001-10-16
EP1783135A1 (de) 2007-05-09
ES2398713T3 (es) 2013-03-21
DE59814056D1 (de) 2007-08-23
EP1019430B1 (de) 2007-07-11
WO1999016781A3 (de) 1999-09-16
CA2305171A1 (en) 1999-04-08
CA2305171C (en) 2008-06-17
US20030199078A1 (en) 2003-10-23
AU1028299A (en) 1999-04-23
JP4659013B2 (ja) 2011-03-30
DE19743518A1 (de) 1999-04-15
US6562568B1 (en) 2003-05-13
ATE366739T1 (de) 2007-08-15
JP2007175060A (ja) 2007-07-12
JP2008134239A (ja) 2008-06-12
DK1019430T3 (da) 2007-11-12

Similar Documents

Publication Publication Date Title
IL135299A0 (en) Automatable method for preparing samples which can be universally applied
US7491495B2 (en) Adsorption of nucleic acids to a solid phase
JP2001518284A5 (xx)
US7329491B2 (en) Methods for isolating nucleic acids
US5658548C1 (en) Nucleic acid purification on silica geland glass mixtures
NO20012700D0 (no) Formuleringer og fremgangsmåter for isolering av nukleinsyrer fra ethvert komplekst utgangsmateriale og etterfölgende kompleksegenetiske analyse
WO1998031840B1 (en) Methods of isolating biological target materials using silica magnetic particles
Reymond et al. A general assay for antibody catalysis using acridone as a fluorescent tag.
AU6114199A (en) Isolation method for nucleic acid and apparatus
CA2271255A1 (en) Affinity purification of polypeptide on protein a matrix
CA2328462A1 (en) Efficient purification of adenovirus
CA2354379A1 (en) Method for isolating dna from biological materials
GB0013658D0 (en) Nucleic acid isolation
AU585557B2 (en) Process for the separation of metals from aqueous media
GB9028038D0 (en) Test method and reagent kit therefor
EP1335003A3 (en) Magnetic carrier capable of binding with protein and purification method of protein utilizing the magnetic carrier
AU5716090A (en) Method for determining nucleic acid
US20090012285A1 (en) Nucleic acid adsorption under low-salt conditions
Juliano et al. Surface polypeptides of the cultured Chinese hamster ovary cell
EP1524317B1 (en) Methods for isolating nucleic acids
CN112159806B (zh) 一种核酸解离液在核酸提取纯化中的应用
AU5995590A (en) Separation of anti-metal chelate antibodies
WO2001002370B1 (en) Nickel-based reagents for detecting dna and dna-protein contacts
US20010034017A1 (en) Process for the isolation and/or purification of a proteinaceous material
Newsom et al. The depletion of molybdenum in the earth, moon, and in the eucrite parent body