IL127916A0 - Erythromycins and process for their preparation - Google Patents
Erythromycins and process for their preparationInfo
- Publication number
- IL127916A0 IL127916A0 IL12791697A IL12791697A IL127916A0 IL 127916 A0 IL127916 A0 IL 127916A0 IL 12791697 A IL12791697 A IL 12791697A IL 12791697 A IL12791697 A IL 12791697A IL 127916 A0 IL127916 A0 IL 127916A0
- Authority
- IL
- Israel
- Prior art keywords
- erythromycins
- preparation
- Prior art date
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Natural products O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9614189.0A GB9614189D0 (en) | 1996-07-05 | 1996-07-05 | Polyketides and their synthesis |
| US2418896P | 1996-08-19 | 1996-08-19 | |
| GBGB9710962.3A GB9710962D0 (en) | 1997-05-28 | 1997-05-28 | Polyketides and their synthesis |
| PCT/GB1997/001810 WO1998001571A2 (en) | 1996-07-05 | 1997-07-04 | Erythromycins and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL127916A0 true IL127916A0 (en) | 1999-11-30 |
Family
ID=27268361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12791697A IL127916A0 (en) | 1996-07-05 | 1997-07-04 | Erythromycins and process for their preparation |
Country Status (28)
| Country | Link |
|---|---|
| EP (3) | EP0909327B1 (is) |
| JP (2) | JP2000511063A (is) |
| KR (1) | KR20000023579A (is) |
| CN (1) | CN1179046C (is) |
| AP (1) | AP1029A (is) |
| AT (2) | ATE296893T1 (is) |
| AU (2) | AU731654B2 (is) |
| BG (1) | BG103133A (is) |
| BR (1) | BR9710209A (is) |
| CA (2) | CA2259420C (is) |
| DE (2) | DE69739688D1 (is) |
| DK (2) | DK0910633T3 (is) |
| EA (1) | EA001744B1 (is) |
| EE (1) | EE03976B1 (is) |
| ES (2) | ES2244001T3 (is) |
| GB (1) | GB2331518B (is) |
| GE (1) | GEP20012348B (is) |
| IL (1) | IL127916A0 (is) |
| IS (1) | IS4940A (is) |
| NO (1) | NO990012L (is) |
| NZ (1) | NZ333861A (is) |
| OA (1) | OA10952A (is) |
| PL (1) | PL331285A1 (is) |
| PT (1) | PT909327E (is) |
| SI (1) | SI0910633T1 (is) |
| SK (1) | SK182498A3 (is) |
| TR (1) | TR199900006T2 (is) |
| WO (2) | WO1998001571A2 (is) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063561A (en) * | 1991-01-17 | 2000-05-16 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| US6060234A (en) * | 1991-01-17 | 2000-05-09 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| US6500960B1 (en) | 1995-07-06 | 2002-12-31 | Stanford University (Board Of Trustees Of The Leland Stanford Junior University) | Method to produce novel polyketides |
| US5712146A (en) | 1993-09-20 | 1998-01-27 | The Leland Stanford Junior University | Recombinant combinatorial genetic library for the production of novel polyketides |
| US20030170725A1 (en) | 1993-09-20 | 2003-09-11 | Chaitan Khosla | Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold |
| US6927057B2 (en) | 1993-09-20 | 2005-08-09 | Kosan Biosciences | Macrolide analogs |
| US6558942B1 (en) | 1994-05-06 | 2003-05-06 | The Leland Stanford Junior University | Combinatorial polyketide libraries produced using a modular PKS gene cluster as scaffold |
| US6495348B1 (en) | 1993-10-07 | 2002-12-17 | Regents Of The University Of Minnesota | Mitomycin biosynthetic gene cluster |
| IL122859A0 (en) | 1995-07-06 | 1998-08-16 | Univ Leland Stanford Junior | Cell-free synthesis of polyketides |
| JP2000502256A (ja) | 1995-12-19 | 2000-02-29 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ポリヒドロキシアルカノエートモノマーシンターゼの代謝エンジニアリング |
| US6271255B1 (en) | 1996-07-05 | 2001-08-07 | Biotica Technology Limited | Erythromycins and process for their preparation |
| US6399789B1 (en) | 1996-12-18 | 2002-06-04 | Kosan Biosciences, Inc. | Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides |
| JP2008169226A (ja) * | 1997-04-30 | 2008-07-24 | Kosan Biosciences Inc | 足場としてモジュラー性ｐｋｓ遺伝子クラスターを使用して生成されるコンビナトリアルなポリケチドライブラリー |
| US6503741B1 (en) | 1998-05-28 | 2003-01-07 | Kosan Biosciences, Inc. | Polyketide synthase genes from Streptomyces venezuelae |
| US6117659A (en) | 1997-04-30 | 2000-09-12 | Kosan Biosciences, Inc. | Recombinant narbonolide polyketide synthase |
| EP0979286B1 (en) | 1997-04-30 | 2014-01-29 | Kosan Biosciences | Combinatorial polyketide libraries produced using a modular pks gene cluster as scaffold |
| US6902913B2 (en) | 1997-04-30 | 2005-06-07 | Kosan Biosciences, Inc. | Recombinant narbonolide polyketide synthase |
| IL133716A0 (en) | 1997-07-10 | 2001-04-30 | Kosan Biosciences Inc | Production of polyketides in plants |
| AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
| WO1999036546A1 (en) * | 1998-01-14 | 1999-07-22 | Glaxo Group Limited | Polyketides and their synthesis |
| NZ509006A (en) * | 1998-05-28 | 2003-09-26 | Kosan Biosciences Inc | Recombinant narbonolide polyketide synthase |
| US6265202B1 (en) | 1998-06-26 | 2001-07-24 | Regents Of The University Of Minnesota | DNA encoding methymycin and pikromycin |
| GB9814006D0 (en) * | 1998-06-29 | 1998-08-26 | Biotica Tech Ltd | Polyketides and their synthesis |
| AU765821B2 (en) | 1998-07-02 | 2003-10-02 | Board Of Regents Of The Leland Stanford Junior University, The | Methods for making polyketides |
| GB9814622D0 (en) * | 1998-07-06 | 1998-09-02 | Biotica Tech Ltd | Polyketides,their preparation,and materials for use therein |
| WO2000024907A2 (en) | 1998-10-28 | 2000-05-04 | Kosan Biosciences, Inc. | Library of novel "unnatural" natural products |
| AU5995299A (en) | 1998-11-03 | 2000-05-22 | Pfizer Products Inc. | Novel macrolide antibiotics |
| US6358712B1 (en) | 1999-01-05 | 2002-03-19 | Trustee Of Boston University | Ordered gene assembly |
| DE60042730D1 (de) | 1999-01-05 | 2009-09-24 | Univ Boston | Verbessertes klonierungsverfahren |
| ATE256694T1 (de) | 1999-01-27 | 2004-01-15 | Pfizer Prod Inc | Ketolid-antibiotika |
| US7001748B2 (en) | 1999-02-09 | 2006-02-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of making polyketides using hybrid polyketide synthases |
| AU2876300A (en) * | 1999-02-09 | 2000-08-29 | Board Of Trustees Of The Leland Stanford Junior University | Methods to mediate polyketide synthase module effectiveness |
| NZ515027A (en) | 1999-04-16 | 2004-01-30 | Kosan Biosciences Inc | Erythromycin derivatives as antibiotics |
| EP1171447A2 (en) | 1999-04-16 | 2002-01-16 | Ortho-McNeil Pharmaceutical, Inc. | Ketolide antibacterials |
| US6451768B1 (en) | 1999-04-16 | 2002-09-17 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6590083B1 (en) | 1999-04-16 | 2003-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | Ketolide antibacterials |
| US6939861B2 (en) | 1999-04-16 | 2005-09-06 | Kosan Biosciences, Inc. | Amido macrolides |
| US6514944B2 (en) | 1999-04-16 | 2003-02-04 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| CN1351608A (zh) | 1999-05-24 | 2002-05-29 | 辉瑞产品公司 | 13－甲基红霉素衍生物 |
| GB9912563D0 (en) * | 1999-05-28 | 1999-07-28 | Biotica Tech Ltd | Polyketides and their synthesis |
| AU2748701A (en) * | 1999-10-29 | 2001-06-06 | Kosan Biosciences, Inc. | Rapamycin analogs |
| EP1101769A3 (en) | 1999-11-18 | 2001-10-24 | Pfizer Products Inc. | Nitrogen containing erythromycin derivatives |
| EP1255763A2 (en) | 2000-02-18 | 2002-11-13 | Kosan Biosciences, Inc. | Motilide compounds |
| EP1146051A3 (en) * | 2000-04-10 | 2001-10-31 | Pfizer Products Inc. | Erythromycin A derivatives |
| ES2338212T3 (es) | 2000-04-13 | 2010-05-05 | Biotica Technology Limited | Productos hibridos glicosilados y su produccion y utilizacion. |
| DK1492404T3 (da) | 2002-02-19 | 2012-04-23 | Dow Agrosciences Llc | Nye spinosyndannende polyketidsyntaser |
| US7300942B2 (en) | 2002-07-16 | 2007-11-27 | Biotica Technology Limited | Production of polyketides and other natural products |
| DK200201957A (da) | 2002-12-20 | 2003-01-20 | Alpharma Aps | 10-substituted erythromycin ketolides and methods of making |
| GB0230217D0 (en) * | 2002-12-27 | 2003-02-05 | Biotica Tech Ltd | Borrelidin-producing polyketide synthase and its uses |
| WO2004112711A2 (en) | 2003-06-16 | 2004-12-29 | Andrx Pharmaceuticals, Llc | Oral extended-release composition |
| GB0327720D0 (en) | 2003-11-28 | 2003-12-31 | Biotica Tech Ltd | Erythromycins and process for their preparation |
| GB0417852D0 (en) | 2004-08-11 | 2004-09-15 | Biotica Tech Ltd | Production of polyketides and other natural products |
| US7582611B2 (en) * | 2005-05-24 | 2009-09-01 | Pfizer Inc. | Motilide compounds |
| EP2342335B1 (en) | 2008-09-24 | 2015-09-16 | Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences | Novel gene cluster |
| GB0904540D0 (en) | 2009-03-17 | 2009-04-29 | Biotica Tech Ltd | Novel compounds and methods for their production |
| GB0914589D0 (en) | 2009-08-20 | 2009-09-30 | Biotica Tech Ltd | Novel compounds and methods for their production |
| WO2011098809A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| WO2011098808A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| WO2011098805A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| GB201118334D0 (en) | 2011-10-24 | 2011-12-07 | Biotica Tech Ltd | Novel dosage form |
| WO2013172782A1 (en) * | 2012-05-16 | 2013-11-21 | Nanyang Technological University | A polyketide synthase construct and its use in the preparation of polyketides |
| EP3247378B8 (en) | 2015-01-09 | 2023-08-23 | Revolution Medicines, Inc. | Macrocyclic compounds that participate in cooperative binding and medical uses thereof |
| KR102359972B1 (ko) | 2016-04-12 | 2022-02-10 | 징코 바이오웍스, 인크. | 화합물의 제조를 위한 조성물 및 방법 |
| WO2018020272A1 (en) | 2016-07-29 | 2018-02-01 | Isomerase Therapeutics Limited | Novel methods |
| US20190264184A1 (en) * | 2016-10-28 | 2019-08-29 | Ginkgo Bioworks, Inc. | Compositions and methods for the production of compounds |
| CN110506120A (zh) | 2016-10-28 | 2019-11-26 | 银杏生物制品公司 | 用于生产化合物的组合物和方法 |
| WO2018153959A1 (en) | 2017-02-22 | 2018-08-30 | Immune System Regulation Holding Ab | Novel immune stimulating macrolides |
| CA3053874A1 (en) | 2017-02-22 | 2018-08-30 | Immune System Regulation Holding Ab | Novel immune stimulating macrolides |
| KR20200134251A (ko) | 2018-03-23 | 2020-12-01 | 아이에스알 임뮨 시스템 레귤레이션 홀딩 에이비 (피유비엘) | 마크로라이드 화합물과 면역 체크포인트 억제제의 조합 |
| CN113766916B (zh) | 2019-01-22 | 2024-04-05 | 艾奥维安制药公司 | Mtorc调节剂及其用途 |
| CR20220240A (es) | 2019-11-04 | 2022-08-03 | Revolution Medicines Inc | Inhibidores de ras |
| US11608346B2 (en) | 2019-11-04 | 2023-03-21 | Revolution Medicines, Inc. | Ras inhibitors |
| IL320513A (en) | 2019-11-04 | 2025-06-01 | Revolution Medicines Inc | RAS inhibitors |
| US11690915B2 (en) | 2020-09-15 | 2023-07-04 | Revolution Medicines, Inc. | Ras inhibitors |
| CR20230558A (es) | 2021-05-05 | 2024-01-24 | Revolution Medicines Inc | Inhibidores de ras para el tratamiento del cáncer |
| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
| KR102775118B1 (ko) | 2022-07-26 | 2025-02-27 | 강원대학교산학협력단 | 에리트로마이신으로 로딩된 키토산 결합 닭뼈유래 수산화인회석 나노입자 및 그 제조방법 |
| CN117288869B (zh) * | 2023-11-24 | 2024-02-09 | 中国医学科学院医药生物技术研究所 | 一种原料药中对甲苯磺酸酯类杂质的检测方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993013663A1 (en) * | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| US6060234A (en) * | 1991-01-17 | 2000-05-09 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| EP0725778B1 (en) * | 1993-09-20 | 2001-09-26 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
| US5712146A (en) * | 1993-09-20 | 1998-01-27 | The Leland Stanford Junior University | Recombinant combinatorial genetic library for the production of novel polyketides |
-
1997
- 1997-07-04 GE GEAP19974661A patent/GEP20012348B/en unknown
- 1997-07-04 SI SI9730793T patent/SI0910633T1/sl unknown
- 1997-07-04 AT AT97930626T patent/ATE296893T1/de active
- 1997-07-04 IL IL12791697A patent/IL127916A0/xx unknown
- 1997-07-04 AU AU34514/97A patent/AU731654B2/en not_active Ceased
- 1997-07-04 PT PT97930626T patent/PT909327E/pt unknown
- 1997-07-04 DK DK97930631.3T patent/DK0910633T3/da active
- 1997-07-04 AT AT97930631T patent/ATE451455T1/de not_active IP Right Cessation
- 1997-07-04 TR TR1999/00006T patent/TR199900006T2/xx unknown
- 1997-07-04 EA EA199900087A patent/EA001744B1/ru not_active IP Right Cessation
- 1997-07-04 NZ NZ333861A patent/NZ333861A/xx unknown
- 1997-07-04 CA CA002259420A patent/CA2259420C/en not_active Expired - Fee Related
- 1997-07-04 WO PCT/GB1997/001810 patent/WO1998001571A2/en not_active Ceased
- 1997-07-04 CA CA002259463A patent/CA2259463A1/en not_active Abandoned
- 1997-07-04 WO PCT/GB1997/001819 patent/WO1998001546A2/en not_active Ceased
- 1997-07-04 PL PL97331285A patent/PL331285A1/xx unknown
- 1997-07-04 JP JP10504933A patent/JP2000511063A/ja not_active Withdrawn
- 1997-07-04 ES ES97930626T patent/ES2244001T3/es not_active Expired - Lifetime
- 1997-07-04 JP JP50492598A patent/JP4173551B2/ja not_active Expired - Fee Related
- 1997-07-04 DE DE69739688T patent/DE69739688D1/de not_active Expired - Lifetime
- 1997-07-04 GB GB9900156A patent/GB2331518B/en not_active Expired - Fee Related
- 1997-07-04 AU AU34509/97A patent/AU731301B2/en not_active Ceased
- 1997-07-04 EE EEP199900014A patent/EE03976B1/xx not_active IP Right Cessation
- 1997-07-04 CN CNB97197649XA patent/CN1179046C/zh not_active Expired - Fee Related
- 1997-07-04 SK SK1824-98A patent/SK182498A3/sk unknown
- 1997-07-04 EP EP97930626A patent/EP0909327B1/en not_active Expired - Lifetime
- 1997-07-04 BR BR9710209-1A patent/BR9710209A/pt not_active Application Discontinuation
- 1997-07-04 DK DK97930626T patent/DK0909327T3/da active
- 1997-07-04 ES ES97930631T patent/ES2337424T3/es not_active Expired - Lifetime
- 1997-07-04 EP EP09178121A patent/EP2182067A3/en not_active Withdrawn
- 1997-07-04 DE DE69733416T patent/DE69733416T2/de not_active Expired - Lifetime
- 1997-07-04 EP EP97930631A patent/EP0910633B1/en not_active Expired - Lifetime
- 1997-07-04 AP APAP/P/1999/001444A patent/AP1029A/en active
-
1999
- 1999-01-04 OA OA9900002A patent/OA10952A/en unknown
- 1999-01-04 IS IS4940A patent/IS4940A/is unknown
- 1999-01-04 NO NO990012A patent/NO990012L/no not_active Application Discontinuation
- 1999-01-05 KR KR1019997000024A patent/KR20000023579A/ko not_active Ceased
- 1999-01-29 BG BG103133A patent/BG103133A/xx unknown
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