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HUS2300008I1 - Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében - Google Patents

Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében

Info

Publication number
HUS2300008I1
HUS2300008I1 HUS2300008C HUS2300008C HUS2300008I1 HU S2300008 I1 HUS2300008 I1 HU S2300008I1 HU S2300008 C HUS2300008 C HU S2300008C HU S2300008 C HUS2300008 C HU S2300008C HU S2300008 I1 HUS2300008 I1 HU S2300008I1
Authority
HU
Hungary
Prior art keywords
ang
vegf
antibodies
treatment
vascular diseases
Prior art date
Application number
HUS2300008C
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48783248&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUS2300008(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HUS2300008I1 publication Critical patent/HUS2300008I1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35Valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
HUS2300008C 2012-07-13 2023-02-14 Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében HUS2300008I1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12176299 2012-07-13
EP13736565.6A EP2872534B1 (en) 2012-07-13 2013-07-11 Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases

Publications (1)

Publication Number Publication Date
HUS2300008I1 true HUS2300008I1 (hu) 2023-02-28

Family

ID=48783248

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE18184973A HUE056217T2 (hu) 2012-07-13 2013-07-11 Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében
HUS2300008C HUS2300008I1 (hu) 2012-07-13 2023-02-14 Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE18184973A HUE056217T2 (hu) 2012-07-13 2013-07-11 Bispecifikus anti-VEGF/anti-ANG-2 antitestek és ezek alkalmazása szemészeti érbetegségek kezelésében

Country Status (41)

Country Link
US (4) US9695233B2 (hu)
EP (2) EP3495387B1 (hu)
JP (5) JP6154900B2 (hu)
KR (1) KR101774121B1 (hu)
CN (1) CN104428315B (hu)
AR (2) AR092027A1 (hu)
AU (1) AU2013288641B2 (hu)
CA (1) CA2874554C (hu)
CL (2) CL2015000061A1 (hu)
CO (1) CO7151542A2 (hu)
CR (1) CR20140542A (hu)
CY (2) CY1124681T1 (hu)
DK (2) DK3495387T3 (hu)
EA (1) EA032192B1 (hu)
ES (2) ES2690312T3 (hu)
FI (1) FIC20230011I1 (hu)
FR (1) FR23C1010I2 (hu)
HR (2) HRP20211641T1 (hu)
HU (2) HUE056217T2 (hu)
IL (1) IL236292B (hu)
IN (1) IN2014DN11157A (hu)
LT (3) LT3495387T (hu)
LU (1) LUC00300I2 (hu)
MA (1) MA37794B1 (hu)
MX (1) MX361337B (hu)
MY (1) MY183712A (hu)
NL (1) NL301218I2 (hu)
NO (1) NO2023009I1 (hu)
NZ (1) NZ702201A (hu)
PE (1) PE20150361A1 (hu)
PH (1) PH12014502713B1 (hu)
PL (2) PL3495387T3 (hu)
PT (1) PT2872534T (hu)
RS (2) RS62509B1 (hu)
SG (1) SG11201408538PA (hu)
SI (2) SI2872534T1 (hu)
SM (1) SMT202100621T1 (hu)
TW (1) TWI506036B (hu)
UA (1) UA120029C2 (hu)
WO (1) WO2014009465A1 (hu)
ZA (1) ZA201408969B (hu)

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TWI506036B (zh) 2015-11-01
AU2013288641A1 (en) 2014-12-11
EP3495387A1 (en) 2019-06-12
PL3495387T3 (pl) 2022-01-10
ES2896493T3 (es) 2022-02-24
FR23C1010I2 (fr) 2024-04-05
LUC00300I2 (hu) 2025-09-22
WO2014009465A1 (en) 2014-01-16
CO7151542A2 (es) 2014-12-29
US9695233B2 (en) 2017-07-04
SI3495387T1 (sl) 2021-12-31
US20230212277A1 (en) 2023-07-06
JP2015527064A (ja) 2015-09-17
UA120029C2 (uk) 2019-09-25
CL2015000061A1 (es) 2015-05-08
EP2872534A1 (en) 2015-05-20
LTC2872534I2 (hu) 2024-10-25
EP3495387B1 (en) 2021-09-01
PH12014502713A1 (en) 2015-02-02

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