HUP9904622A3 - 1,4-di-sustituted piperidines as muscarinic antagonists - Google Patents

1,4-di-sustituted piperidines as muscarinic antagonists

Info

Publication number: HUP9904622A3
Authority: HU; Hungary
Prior art keywords: sustituted; piperidines; muscarinic antagonists; muscarinic; antagonists
Prior art date: 1996-07-10

Application number

HU9904622A

Other languages

English (en)

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-10

Filing date

1997-07-08

Publication date

2001-07-30

1997-07-08 Application filed by Schering Corp filed Critical Schering Corp

2000-06-28 Publication of HUP9904622A2 publication Critical patent/HUP9904622A2/hu

2001-07-30 Publication of HUP9904622A3 publication Critical patent/HUP9904622A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

HU9904622A 1996-07-10 1997-07-08 1,4-di-sustituted piperidines as muscarinic antagonists HUP9904622A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67861896A	1996-07-10	1996-07-10
PCT/US1997/011176 WO1998001425A1 (en)	1996-07-10	1997-07-08	1,4-di-sustituted piperidines as muscarinic antagonists

Publications (2)

Publication Number	Publication Date
HUP9904622A2 HUP9904622A2 (hu)	2000-06-28
HUP9904622A3 true HUP9904622A3 (en)	2001-07-30

Family

ID=24723553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9904622A HUP9904622A3 (en)	1996-07-10	1997-07-08	1,4-di-sustituted piperidines as muscarinic antagonists

Country Status (14)

Country	Link
EP (1)	EP0912515B1 (hu)
JP (1)	JP3068206B2 (hu)
KR (1)	KR20000023599A (hu)
AT (1)	ATE227708T1 (hu)
AU (1)	AU728592B2 (hu)
CA (1)	CA2259655C (hu)
DE (1)	DE69717109T2 (hu)
DK (1)	DK0912515T3 (hu)
ES (1)	ES2182104T3 (hu)
HU (1)	HUP9904622A3 (hu)
IL (1)	IL127942A0 (hu)
NZ (1)	NZ333513A (hu)
PT (1)	PT912515E (hu)
WO (1)	WO1998001425A1 (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6251919B1 (en) *	1998-02-27	2001-06-26	Warner-Lambert	Heterocyclic substituted aniline calcium channel blockers
US6635646B1 (en)	1999-05-04	2003-10-21	Schering Corporation	Pegylated interferon alfa-CCR5 antagonist combination HIV therapy
SK286968B6 (sk) *	1999-05-04	2009-08-06	Schering Corporation	Piperidín-piperidinyl ako CCR5 antagonista, farmaceutický prostriedok s jeho obsahom a jeho použitie
US6387930B1 (en)	1999-05-04	2002-05-14	Schering Corporation	Piperidine derivatives useful as CCR5 antagonists
AR033517A1 (es)	2000-04-08	2003-12-26	Astrazeneca Ab	Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos
DE60113090T2 (de)	2000-04-28	2006-06-29	F. Hoffmann-La Roche Ag	P-(sulfonyl)-aryl- und -heteroarylamine
US6640155B2 (en)	2000-08-22	2003-10-28	Lam Research Corporation	Chemical mechanical polishing apparatus and methods with central control of polishing pressure applied by polishing head
ES2258642T3 (es)	2001-07-02	2006-09-01	Astrazeneca Ab	Derivados de piperidina utiles como moduladores de la actividad del receptor de quimiocina.
GB0120461D0 (en)	2001-08-22	2001-10-17	Astrazeneca Ab	Novel compounds
AR036366A1 (es)	2001-08-29	2004-09-01	Schering Corp	Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit
GB0122503D0 (en)	2001-09-18	2001-11-07	Astrazeneca Ab	Chemical compounds
RU2311408C2 (ru)	2001-12-03	2007-11-27	Ф.Хоффманн-Ля Рош Аг	Производные аминотетралина в качестве антагонистов мускаринового рецептора
SE0200843D0 (sv)	2002-03-19	2002-03-19	Astrazeneca Ab	Chemical compounds
SE0200844D0 (sv)	2002-03-19	2002-03-19	Astrazeneca Ab	Chemical compounds
JP4675103B2 (ja) *	2002-06-14	2011-04-20	富山化学工業株式会社	脳機能を改善する医薬組成物および脳機能を改善するための方法
SE0202838D0 (sv) *	2002-09-24	2002-09-24	Astrazeneca Ab	Chemical compounds
GB0223223D0 (en) *	2002-10-07	2002-11-13	Novartis Ag	Organic compounds
RU2224516C1 (ru) *	2002-10-17	2004-02-27	Государственное учреждение Институт токсикологии	Гидрохлорид 1-фенил-1-циклопентил-4-пиперидино-2-бутин-1-ола (пентифин), обладающий м4 холиноблокирующей активностью
SE0300957D0 (sv)	2003-04-01	2003-04-01	Astrazeneca Ab	Chemical compounds
WO2006034473A2 (en)	2004-09-23	2006-03-30	Reddy Us Therapeutics, Inc.	Novel pyrimidine compounds, process for their preparation and compositions containing them
WO2007011293A1 (en)	2005-07-21	2007-01-25	Astrazeneca Ab	Novel piperidine derivatives
JP2009503103A (ja)	2005-08-02	2009-01-29	レキシコン・ファーマシューティカルズ・インコーポレーテッド	アリールピリジン及びその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1042029C (zh) *	1993-07-28	1999-02-10	参天制药株式会社	1,4－(二苯基烷基)哌嗪衍生物及含有它的药物组合物
IL117149A0 (en) *	1995-02-23	1996-06-18	Schering Corp	Muscarinic antagonists

1997
- 1997-07-08 PT PT97932321T patent/PT912515E/pt unknown
- 1997-07-08 ES ES97932321T patent/ES2182104T3/es not_active Expired - Lifetime
- 1997-07-08 DE DE69717109T patent/DE69717109T2/de not_active Expired - Fee Related
- 1997-07-08 JP JP10505232A patent/JP3068206B2/ja not_active Expired - Fee Related
- 1997-07-08 AU AU35810/97A patent/AU728592B2/en not_active Ceased
- 1997-07-08 NZ NZ333513A patent/NZ333513A/xx unknown
- 1997-07-08 WO PCT/US1997/011176 patent/WO1998001425A1/en not_active Ceased
- 1997-07-08 DK DK97932321T patent/DK0912515T3/da active
- 1997-07-08 HU HU9904622A patent/HUP9904622A3/hu unknown
- 1997-07-08 CA CA002259655A patent/CA2259655C/en not_active Expired - Fee Related
- 1997-07-08 EP EP97932321A patent/EP0912515B1/en not_active Expired - Lifetime
- 1997-07-08 IL IL12794297A patent/IL127942A0/xx unknown
- 1997-07-08 AT AT97932321T patent/ATE227708T1/de not_active IP Right Cessation
1999
- 1999-01-07 KR KR1019997000045A patent/KR20000023599A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
JPH11514671A (ja)	1999-12-14
ATE227708T1 (de)	2002-11-15
DE69717109T2 (de)	2003-04-30
JP3068206B2 (ja)	2000-07-24
DK0912515T3 (da)	2003-03-10
CA2259655A1 (en)	1998-01-15
EP0912515B1 (en)	2002-11-13
DE69717109D1 (de)	2002-12-19
CA2259655C (en)	2003-05-13
EP0912515A1 (en)	1999-05-06
IL127942A0 (en)	1999-11-30
NZ333513A (en)	2000-04-28
KR20000023599A (ko)	2000-04-25
HUP9904622A2 (hu)	2000-06-28
PT912515E (pt)	2003-03-31
AU3581097A (en)	1998-02-02
WO1998001425A1 (en)	1998-01-15
AU728592B2 (en)	2001-01-11
ES2182104T3 (es)	2003-03-01

Publication	Publication Date	Title
ZA977011B (en)	1998-02-06	Muscarinic antagonists.
HUP9904622A3 (en)	2001-07-30	1,4-di-sustituted piperidines as muscarinic antagonists
AU1842995A (en)	1995-09-04	N-acylpiperidine tachykinin antagonists
AU4343796A (en)	1996-07-03	Tachykinin antagonists
AU2957997A (en)	1997-12-09	1,2,4-oxadiazoles as adhesion-receptor antagonists
EP0912175A4 (en)	1999-09-08	FIBRINOGENIC RECEPTOR ANTAGONISTS
EP0885213A4 (en)	1999-04-28	FIBRINOGEN RECEPTOR ANTAGONISTS
HUP9903590A3 (en)	2002-01-28	3-azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists
IL140249A0 (en)	2002-02-10	Muscarinic antagonists
EP0796098A4 (en)	1998-04-29	FIBRINOGEN RECEPTOR ANTAGONISTS
EP0801650A4 (en)	1998-05-06	FIBRINOGEN RECEPTOR ANTAGONISTS
IL142045A0 (en)	2002-03-10	Naphthalenecarboxamides as tachykinin receptor antagonists
ZA978792B (en)	1998-04-06	N-substituted azaheterocyclic compounds.
ZA988938B (en)	1999-10-05	Amorphous paroxetine composition.
ZA98256B (en)	1998-07-14	Tachykinin antagonists
EP0794779A4 (en)	1998-04-29	FIBRINOGENIC RECEPTOR ANTAGONISTS
ZA9710653B (en)	1998-06-03	4-hydroxy-piperidine derivatives.
GB9515852D0 (en)	1995-10-04	Fibrinogen receptor antagonists
HUP9903653A3 (en)	2001-05-28	Substituted arylalkylamines as neurokinin antagonists
AU7856194A (en)	1995-05-22	N-benzoyl-4-oxy/thio-2-substituted piperidines as substance-p receptor antagonists
IL124867A0 (en)	1999-01-26	1, 4-dihydropyridine compounds as bradykinin antagonists
EP0800395A4 (en)	1998-04-29	FIBRINOGENIC RECEPTOR ANTAGONISTS
GB9516643D0 (en)	1995-10-18	Fibrinogen receptor antagonists
HUP0204169A3 (en)	2005-03-29	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines an
ZA961293B (en)	1996-08-19	Muscarinic antagonists