AU2957997A - 1,2,4-oxadiazoles as adhesion-receptor antagonists - Google Patents
1,2,4-oxadiazoles as adhesion-receptor antagonistsInfo
- Publication number
- AU2957997A AU2957997A AU29579/97A AU2957997A AU2957997A AU 2957997 A AU2957997 A AU 2957997A AU 29579/97 A AU29579/97 A AU 29579/97A AU 2957997 A AU2957997 A AU 2957997A AU 2957997 A AU2957997 A AU 2957997A
- Authority
- AU
- Australia
- Prior art keywords
- oxadiazoles
- adhesion
- receptor antagonists
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000005071 1,2,4-oxadiazoles Chemical class 0.000 title 1
- 102000019997 adhesion receptor Human genes 0.000 title 1
- 108010013985 adhesion receptor Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19620041A DE19620041A1 (en) | 1996-05-17 | 1996-05-17 | Adhesion receptor antagonists |
| DE19620041 | 1996-05-17 | ||
| PCT/EP1997/002555 WO1997044333A1 (en) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazoles as adhesion-receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2957997A true AU2957997A (en) | 1997-12-09 |
Family
ID=7794651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU29579/97A Abandoned AU2957997A (en) | 1996-05-17 | 1997-05-20 | 1,2,4-oxadiazoles as adhesion-receptor antagonists |
Country Status (5)
| Country | Link |
|---|---|
| AR (1) | AR007160A1 (en) |
| AU (1) | AU2957997A (en) |
| DE (1) | DE19620041A1 (en) |
| WO (1) | WO1997044333A1 (en) |
| ZA (1) | ZA974234B (en) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2263998A1 (en) * | 1996-08-29 | 1998-03-05 | Michael F. Sugrue | Compositions and methods for administering integrin receptor antagonists |
| HUP0103304A3 (en) | 1998-01-28 | 2002-10-28 | Shionogi & Co | Novel tricyclic compounds and pharmaceutical compositions thereof |
| GB9805655D0 (en) | 1998-03-16 | 1998-05-13 | Celltech Therapeutics Ltd | Chemical compounds |
| US6521626B1 (en) | 1998-03-24 | 2003-02-18 | Celltech R&D Limited | Thiocarboxamide derivatives |
| CA2333927A1 (en) * | 1998-04-01 | 1999-10-07 | Dupont Pharmaceuticals Company | Pyrimidines and triazines as integrin antagonists |
| GB9814414D0 (en) | 1998-07-03 | 1998-09-02 | Celltech Therapeutics Ltd | Chemical compounds |
| EP1100506A4 (en) * | 1998-07-29 | 2002-06-26 | Merck & Co Inc | INTEGRIN RECEPTOR ANTAGONISTS |
| GB9821061D0 (en) | 1998-09-28 | 1998-11-18 | Celltech Therapeutics Ltd | Chemical compounds |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| GB9826174D0 (en) | 1998-11-30 | 1999-01-20 | Celltech Therapeutics Ltd | Chemical compounds |
| US6518283B1 (en) | 1999-05-28 | 2003-02-11 | Celltech R&D Limited | Squaric acid derivatives |
| US6534513B1 (en) | 1999-09-29 | 2003-03-18 | Celltech R&D Limited | Phenylalkanoic acid derivatives |
| US6455539B2 (en) | 1999-12-23 | 2002-09-24 | Celltech R&D Limited | Squaric acid derivates |
| EP1332132B1 (en) | 2000-04-17 | 2007-10-10 | UCB Pharma, S.A. | Enamine derivatives as cell adhesion molecules |
| US6403608B1 (en) | 2000-05-30 | 2002-06-11 | Celltech R&D, Ltd. | 3-Substituted isoquinolin-1-yl derivatives |
| US6545013B2 (en) | 2000-05-30 | 2003-04-08 | Celltech R&D Limited | 2,7-naphthyridine derivatives |
| US6933304B2 (en) | 2000-06-15 | 2005-08-23 | Pharmacia Corporation | Heteroarylalkanoic acids as integrin receptor antagonists |
| JP2004502762A (en) | 2000-07-07 | 2004-01-29 | セルテック アール アンド ディ リミテッド | Squaric acid derivatives as integrin antagonists containing bicyclic heteroaromatic rings |
| JP2004505110A (en) | 2000-08-02 | 2004-02-19 | セルテック アール アンド ディ リミテッド | 3-position substituted isoquinolin-1-yl derivative |
| US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| EP1406632A4 (en) * | 2001-06-08 | 2009-11-04 | Cytovia Inc | 3-ARYL-5-ARYL-1,2,4-OXADIAZOLES AND THEIR ANALOGUES, CASPASE ACTIVATORS AND INDUCERS OF APOPTOSIS, AND USES THEREOF |
| EP1549640A4 (en) | 2002-06-17 | 2008-08-06 | Merck & Co Inc | 1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) AZETIDIN-3-CARBOXYLATES AND 1 - ((5-ARYL-1,2,4-OXADIAZOL-3-YL) BENZYL) PYRROLIDINE-3-CARBOXYLATES AS EDG RECEPTOR AGONISTS |
| JP2006516144A (en) | 2002-12-20 | 2006-06-22 | ファルマシア・コーポレーション | Thiazole compounds as integrin receptor antagonist derivatives |
| CA2507699A1 (en) * | 2002-12-20 | 2004-07-15 | Pharmacia Corporation | Heteroarylalkanoic acids as integrin receptor antagonists |
| GB0303503D0 (en) * | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
| ES2926542T3 (en) | 2003-04-11 | 2022-10-26 | Ptc Therapeutics Inc | 1,2,4-oxadiazole benzoic acid compounds and their use for suppression of nonsense mutations and treatment of diseases |
| CA2547198A1 (en) | 2003-12-17 | 2005-06-30 | Merck & Co., Inc. | (3,4-disubstituted)propanoic carboxylates as s1p (edg) receptor agonists |
| EP2301536B1 (en) | 2004-10-13 | 2014-04-09 | PTC Therapeutics, Inc. | Compounds and their use for treating nonsense-related diseases |
| KR20080014009A (en) * | 2005-06-08 | 2008-02-13 | 노파르티스 아게 | Polycyclic oxadiazoles or isoxazoles, and their use as S1P receptor ligands |
| US20090325924A1 (en) * | 2005-06-30 | 2009-12-31 | Stuart Edward | GPCR Agonists |
| JP5367563B2 (en) | 2006-03-30 | 2013-12-11 | ピーティーシー セラピューティクス，インコーポレーテッド | Method for the production of functional proteins from DNA having nonsense mutations and treatment of disorders associated therewith |
| MX2009000286A (en) | 2006-06-26 | 2009-03-20 | Procter & Gamble | Prolyl hydroxylase inhibitors and methods of use. |
| JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Compounds |
| BRPI0914629A2 (en) * | 2008-06-24 | 2019-09-24 | Irm Llc | compounds and methods for modulating g protein-coupled receptors |
| RU2602498C2 (en) | 2011-06-06 | 2016-11-20 | Акебиа Терапеутикс Инк. | Compounds and compositions for stabilisation of hypoxia induced factor-2 alpha as method of cancer medical treatment |
| NO2686520T3 (en) | 2011-06-06 | 2018-03-17 | ||
| HUE066123T2 (en) | 2013-06-13 | 2024-07-28 | Akebia Therapeutics Inc | Compositions and methods for treating anemia |
| TW201946625A (en) | 2013-11-15 | 2019-12-16 | 美商阿克比治療有限公司 | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| EP3113619A4 (en) | 2014-03-06 | 2017-09-13 | PTC Therapeutics, Inc. | Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid |
| CN107427503A (en) | 2015-01-23 | 2017-12-01 | 阿克比治疗有限公司 | The solid form, its composition and purposes of 2 (5 (3 fluorophenyl) 3 pyridone formamide) acetic acid |
| US11324734B2 (en) | 2015-04-01 | 2022-05-10 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| BR112018008838A8 (en) | 2015-10-30 | 2019-02-26 | Ptc Therapeutics Inc | method for treating, preventing, ameliorating or administering an epileptic disorder |
| JP7440989B2 (en) | 2018-05-09 | 2024-02-29 | アケビア セラピューティクス インコーポレイテッド | Method for preparing 2-[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
| GB202209228D0 (en) * | 2022-06-23 | 2022-08-10 | Univ Strathclyde | Modified amino acids and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB935523A (en) * | 1961-06-17 | 1963-08-28 | Acraf | New sulphamido-oxadiazoles |
| JPS51143669A (en) * | 1975-06-06 | 1976-12-10 | Takeda Chem Ind Ltd | A process for preparing 1,2,4- oxadiazole derivatives |
| JPS52272A (en) * | 1975-10-17 | 1977-01-05 | Takeda Chem Ind Ltd | Process for preparing 1,2,4-oxadiazole derivatives |
| US4135910A (en) * | 1977-05-12 | 1979-01-23 | Monsanto Company | Oxadiazol-3-yl-benzoates as plant growth regulants |
| WO1994022846A1 (en) * | 1993-03-30 | 1994-10-13 | Pfizer Inc. | Compounds enhancing antitumor activity of other cytotoxic agents |
-
1996
- 1996-05-17 DE DE19620041A patent/DE19620041A1/en not_active Withdrawn
-
1997
- 1997-05-15 ZA ZA9704234A patent/ZA974234B/en unknown
- 1997-05-16 AR ARP970102054A patent/AR007160A1/en unknown
- 1997-05-20 AU AU29579/97A patent/AU2957997A/en not_active Abandoned
- 1997-05-20 WO PCT/EP1997/002555 patent/WO1997044333A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AR007160A1 (en) | 1999-10-13 |
| WO1997044333A1 (en) | 1997-11-27 |
| DE19620041A1 (en) | 1998-01-29 |
| ZA974234B (en) | 1997-12-11 |
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