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HUP0102818A3 - Process for purification of citalopram - Google Patents

Process for purification of citalopram

Info

Publication number
HUP0102818A3
HUP0102818A3 HU0102818A HUP0102818A HUP0102818A3 HU P0102818 A3 HUP0102818 A3 HU P0102818A3 HU 0102818 A HU0102818 A HU 0102818A HU P0102818 A HUP0102818 A HU P0102818A HU P0102818 A3 HUP0102818 A3 HU P0102818A3
Authority
HU
Hungary
Prior art keywords
citalopram
purification
Prior art date
Application number
HU0102818A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HU0102818D0 publication Critical patent/HU0102818D0/hu
Publication of HUP0102818A2 publication Critical patent/HUP0102818A2/hu
Publication of HUP0102818A3 publication Critical patent/HUP0102818A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0102818A 2000-12-28 2001-07-05 Process for purification of citalopram HUP0102818A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001943 2000-12-28

Publications (3)

Publication Number Publication Date
HU0102818D0 HU0102818D0 (en) 2001-09-28
HUP0102818A2 HUP0102818A2 (hu) 2001-12-28
HUP0102818A3 true HUP0102818A3 (en) 2003-07-28

Family

ID=8159933

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0101028A HU0101028D0 (en) 2000-12-28 2001-03-09 Process for the preparation of pure citalopram
HU0102818A HUP0102818A3 (en) 2000-12-28 2001-07-05 Process for purification of citalopram

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0101028A HU0101028D0 (en) 2000-12-28 2001-03-09 Process for the preparation of pure citalopram

Country Status (41)

Country Link
US (2) US6855834B2 (hu)
EP (1) EP1181272B1 (hu)
JP (1) JP2003519121A (hu)
KR (1) KR100430746B1 (hu)
CN (1) CN1366526A (hu)
AR (1) AR029898A1 (hu)
AT (2) ATE222899T1 (hu)
AU (3) AU2001100399B4 (hu)
BE (2) BE1013417A6 (hu)
BG (1) BG106219A (hu)
BR (1) BR0106271A (hu)
CA (1) CA2359810C (hu)
CH (1) CH691536A5 (hu)
CZ (1) CZ293140B6 (hu)
DE (1) DE60100016T2 (hu)
DK (1) DK1181272T3 (hu)
EA (1) EA003459B1 (hu)
ES (2) ES2181663T3 (hu)
FI (2) FI108640B (hu)
FR (1) FR2818977B1 (hu)
GB (2) GB2356199B (hu)
GR (1) GR20010100131A (hu)
HK (1) HK1049332A1 (hu)
HR (1) HRP20020005A2 (hu)
HU (2) HU0101028D0 (hu)
IE (2) IES20010253A2 (hu)
IL (1) IL147162A0 (hu)
IS (1) IS5884A (hu)
IT (1) ITMI20010604A1 (hu)
MX (1) MXPA01013336A (hu)
NL (1) NL1017534C1 (hu)
NO (1) NO313047B1 (hu)
NZ (1) NZ516299A (hu)
PL (1) PL353369A1 (hu)
PT (1) PT1181272E (hu)
SE (1) SE0103044L (hu)
SK (1) SK284418B6 (hu)
TR (1) TR200200018T1 (hu)
UA (1) UA71635C2 (hu)
WO (1) WO2001047877A2 (hu)
ZA (1) ZA200110133B (hu)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
SI1173431T2 (sl) * 1999-04-14 2009-12-31 Lundbeck & Co As H Postopek za pripravo citaloprama
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
TR200101874T1 (tr) 1999-10-25 2002-02-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem
HUP0200169A3 (en) 1999-10-25 2002-11-28 Lundbeck & Co As H Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
SI1246812T1 (en) 1999-12-28 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
SI1246813T1 (en) 1999-12-30 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
CZ20022601A3 (cs) 2000-01-14 2002-10-16 H. Lundbeck A/S Způsob výroby 5-kyanoftalidu
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
TR200202195T2 (tr) 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
PL360107A1 (en) 2000-03-14 2004-09-06 H.Lundbeck A/S Method for the preparation of citalopram
WO2001068632A1 (en) * 2000-03-16 2001-09-20 H. Lundbeck A/S Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
ES2228824T3 (es) 2000-12-22 2005-04-16 H. Lundbeck A/S Metodo de preparacion de citalopram puro.
ATE222899T1 (de) 2000-12-28 2002-09-15 Lundbeck & Co As H Verfahren zur herstellung von reinem citalopram
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation
WO2003057132A2 (en) 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135959C (hu) 1964-12-23
GB1143702A (hu) * 1965-03-18
DE1619713A1 (de) * 1967-03-29 1970-12-17 Leybold Heraeus Gmbh & Co Kg Vorrichtung zur Vakuum- und Kurzwegdestillation
DE2135085C3 (de) 1971-07-14 1981-12-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Wiedergewinnung von Caprolactam aus einem Gemisch, das Caprolactam und dessen Oligomere enthält
DE2442426C2 (de) * 1974-09-05 1983-04-07 Bayer Ag, 5090 Leverkusen Diisocyanatodiketene, Verfahren zu deren Herstellung und deren Verwendung
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
IT8020902A0 (it) 1980-03-25 1980-03-25 Snia Viscosa Procedimento ed apparecchiatura per la separazione continua per via termica di miscele liquide dicomposti termolabili.
JPS6082101A (ja) 1983-10-13 1985-05-10 Mitsui Toatsu Chem Inc 高沸点重合性化合物の薄膜蒸留による精製方法
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
FR2656305B1 (fr) 1989-12-22 1992-04-10 Norsolor Sa Procede de purification du (meth)acrylate de glycidyle.
US5296507A (en) * 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
US5582692A (en) 1994-10-07 1996-12-10 Artisan Industries, Inc. Method for the purification of vitamin E
US6136991A (en) * 1996-05-21 2000-10-24 Exxon Chemical Patents Inc. Glycidyl ester adducts having increased glass transition temperatures
JP2001501587A (ja) 1996-05-21 2001-02-06 エクソン・ケミカル・パテンツ・インク エピハロヒドリン及びカルボン酸からのグリシジルエステルの改良された精製方法
DE19626659A1 (de) * 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) * 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DK1015416T3 (da) 1997-07-08 2001-11-05 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
DE19734673A1 (de) * 1997-08-11 1999-02-18 Rwe Dea Ag Verfahren zur Herstellung von metallfreien Guerbetalkoholen
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
SK283907B6 (sk) 1997-11-11 2004-04-06 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
DE69920329T3 (de) * 1998-06-19 2009-07-09 Shin-Etsu Chemical Co., Ltd. Destillationsverfahren für (Meth)acryloxysilane
ES2189502T3 (es) * 1998-10-20 2003-07-01 Lundbeck & Co As H Metodo para la prevencion de citalopram.
KR100454008B1 (ko) 1998-12-23 2004-10-20 하. 룬트벡 아크티에 셀스카브 5-시아노프탈리드의 제조방법
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
SI1173431T2 (sl) 1999-04-14 2009-12-31 Lundbeck & Co As H Postopek za pripravo citaloprama
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
TR200101874T1 (tr) 1999-10-25 2002-02-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
ES2228824T3 (es) 2000-12-22 2005-04-16 H. Lundbeck A/S Metodo de preparacion de citalopram puro.
ATE222899T1 (de) 2000-12-28 2002-09-15 Lundbeck & Co As H Verfahren zur herstellung von reinem citalopram
US6781003B1 (en) * 2003-06-09 2004-08-24 Aurobindo Pharma Ltd. Preparation of pure citalopram

Also Published As

Publication number Publication date
CA2359810A1 (en) 2001-07-05
TR200200018T1 (tr) 2002-06-21
HU0102818D0 (en) 2001-09-28
CH691536A5 (de) 2001-08-15
ES2170733B1 (es) 2003-12-16
BG106219A (en) 2002-08-30
SE0103044L (sv) 2002-06-29
ATE222899T1 (de) 2002-09-15
BE1013417A6 (fr) 2001-12-04
SK284418B6 (sk) 2005-04-01
SE0103044D0 (sv) 2001-09-14
ITMI20010604A0 (it) 2001-03-22
BR0106271A (pt) 2002-05-21
SK18472001A3 (sk) 2002-05-09
CZ2001891A3 (cs) 2002-08-14
EA003459B1 (ru) 2003-06-26
FR2818977A1 (fr) 2002-07-05
US20030178295A1 (en) 2003-09-25
CA2359810C (en) 2002-11-05
WO2001047877A2 (en) 2001-07-05
FI20010501A0 (fi) 2001-03-13
GB2356199A (en) 2001-05-16
NZ516299A (en) 2002-12-20
AR029898A1 (es) 2003-07-23
GR20010100131A (el) 2002-10-09
NO313047B1 (no) 2002-08-05
ITMI20010604A1 (it) 2002-09-22
AU750006B1 (en) 2002-07-11
EA200200016A1 (ru) 2002-04-25
ES2181663T3 (es) 2003-03-01
AU3920201A (en) 2001-07-09
KR100430746B1 (ko) 2004-05-10
NO20011272D0 (no) 2001-03-13
UA71635C2 (uk) 2004-12-15
MXPA01013336A (es) 2002-07-09
NL1017534C1 (nl) 2001-04-26
KR20020073379A (ko) 2002-09-26
DE60100016D1 (de) 2002-10-02
ES2170733A1 (es) 2002-08-01
FI20011578A0 (fi) 2001-07-26
CZ293140B6 (cs) 2004-02-18
IL147162A0 (en) 2002-08-14
IES20010632A2 (en) 2002-03-06
PL353369A1 (en) 2003-11-17
HU0101028D0 (en) 2001-05-28
WO2001047877A3 (en) 2001-12-27
JP2003519121A (ja) 2003-06-17
DK1181272T3 (da) 2002-12-30
NO20011272L (no) 2002-07-01
AT4368U1 (de) 2001-06-25
HRP20020005A2 (en) 2003-04-30
ZA200110133B (en) 2003-01-13
US6855834B2 (en) 2005-02-15
IES20010253A2 (en) 2002-03-06
IS5884A (is) 2002-06-28
BE1013316A6 (fr) 2001-11-06
FI108640B (fi) 2002-02-28
AU2001100399A4 (en) 2001-11-01
CN1366526A (zh) 2002-08-28
DE60100016T2 (de) 2003-04-17
GB0105981D0 (en) 2001-05-02
GB2361697A (en) 2001-10-31
HUP0102818A2 (hu) 2001-12-28
US20020087012A1 (en) 2002-07-04
EP1181272A2 (en) 2002-02-27
PT1181272E (pt) 2003-01-31
GB2356199B (en) 2001-10-03
EP1181272B1 (en) 2002-08-28
FR2818977B1 (fr) 2003-12-05
GB0117095D0 (en) 2001-09-05
AU2001100399B4 (en) 2002-03-21
HK1049332A1 (zh) 2003-05-09

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees