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HN2010002683A - Compuesto 2-fluoro-11-(piperazin-1-il)dibenzo [b,f][1,4]tiazepina - Google Patents

Compuesto 2-fluoro-11-(piperazin-1-il)dibenzo [b,f][1,4]tiazepina

Info

Publication number
HN2010002683A
HN2010002683A HN2010002683A HN2010002683A HN2010002683A HN 2010002683 A HN2010002683 A HN 2010002683A HN 2010002683 A HN2010002683 A HN 2010002683A HN 2010002683 A HN2010002683 A HN 2010002683A HN 2010002683 A HN2010002683 A HN 2010002683A
Authority
HN
Honduras
Prior art keywords
tiazepina
dibenzo
piperazin
fluoro
compound
Prior art date
Application number
HN2010002683A
Other languages
English (en)
Inventor
Brown Dean
R Damewood James
Edwards Phil
Campbell James
M Muir
Pierson Edward
Bhikkappashenvi Ashokkumar
Wesolowski Steven
Widzowski Dan
Wood Michael
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41431860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HN2010002683(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HN2010002683A publication Critical patent/HN2010002683A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16[b, f]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE LA SIGUENTE FORMULA: I DENDE Z SE DESCRIBE EN LA DESCRIPCION, SALES FARMACEUTICAMENTE ACEPTABLES DE ESTOS, COMPOSICIONES QUE LOS COMPRENDEN Y METODOS PARA TRATAR EL TRASTORNO BIPOLAR, UN TRASTORNO DE ANSIEDAD, UN TRASTORNO DE ESTADO DE ANIMO O LA ESQUIZOFRENIA, U OTRO TRASTORNO PSICOTICO CON DICHOS COMPUESTOS.
HN2010002683A 2008-06-20 2010-12-20 Compuesto 2-fluoro-11-(piperazin-1-il)dibenzo [b,f][1,4]tiazepina HN2010002683A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7441708P 2008-06-20 2008-06-20

Publications (1)

Publication Number Publication Date
HN2010002683A true HN2010002683A (es) 2013-01-15

Family

ID=41431860

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2010002683A HN2010002683A (es) 2008-06-20 2010-12-20 Compuesto 2-fluoro-11-(piperazin-1-il)dibenzo [b,f][1,4]tiazepina

Country Status (37)

Country Link
US (3) US20110160184A1 (es)
EP (1) EP2307389B1 (es)
JP (2) JP5468068B2 (es)
KR (1) KR20110019781A (es)
CN (1) CN102131791B (es)
AR (1) AR072200A1 (es)
AU (1) AU2009260905B2 (es)
BR (1) BRPI0914231A2 (es)
CA (1) CA2728675A1 (es)
CL (1) CL2010001471A1 (es)
CR (1) CR11860A (es)
CU (1) CU23884B1 (es)
CY (1) CY1113845T1 (es)
DK (1) DK2307389T3 (es)
DO (1) DOP2010000393A (es)
EA (1) EA201001889A1 (es)
EC (1) ECSP10010698A (es)
ES (1) ES2402084T3 (es)
HN (1) HN2010002683A (es)
HR (1) HRP20130234T1 (es)
IL (2) IL210081A (es)
ME (1) ME01516B (es)
MX (1) MX2010014203A (es)
MY (1) MY157518A (es)
NI (1) NI201000224A (es)
NZ (1) NZ590616A (es)
PE (1) PE20110029A1 (es)
PL (1) PL2307389T3 (es)
PT (1) PT2307389E (es)
RS (1) RS52703B (es)
SI (1) SI2307389T1 (es)
SV (1) SV2010003769A (es)
TW (1) TWI488854B (es)
UA (1) UA105903C2 (es)
UY (1) UY31919A (es)
WO (1) WO2009154563A1 (es)
ZA (1) ZA201100488B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY157518A (en) * 2008-06-20 2016-06-15 Astrazeneca Ab Dibenzothiazepine derivatives and use thereof
KR20160043029A (ko) * 2013-08-12 2016-04-20 그라파이트 소프트웨어 코포레이션 보안 인증 및 암호화된 도메인들로의 스위칭
CN103524455A (zh) * 2013-10-30 2014-01-22 苏州敬业医药化工有限公司 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法
CA2931289C (en) 2013-11-21 2023-10-17 Graphite Software Corporation Managed domains for remote content and configuration control on mobile information devices
CN104447615A (zh) * 2014-02-28 2015-03-25 广东东阳光药业有限公司 喹硫平中间体的制备方法
EP4428132A1 (en) * 2023-03-08 2024-09-11 Johann-Wolfgang-Goethe-Universität Frankfurt am Main Slack-activating compounds and their medical use
KR20250153284A (ko) * 2023-03-08 2025-10-24 요한 볼프강 괴테 우니베르시타트, 프랑크프루트 암 마인 슬랙(Slack) 활성화 화합물 및 이의 의학적 용도

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Also Published As

Publication number Publication date
WO2009154563A1 (en) 2009-12-23
IL229560A0 (en) 2014-01-30
EP2307389B1 (en) 2013-01-23
EP2307389A4 (en) 2012-04-11
TW201002702A (en) 2010-01-16
UA105903C2 (uk) 2014-07-10
US20120202991A1 (en) 2012-08-09
PE20110029A1 (es) 2011-02-11
US20090318415A1 (en) 2009-12-24
NI201000224A (es) 2012-03-19
ES2402084T3 (es) 2013-04-26
CR11860A (es) 2011-02-25
UY31919A (es) 2010-01-29
DOP2010000393A (es) 2011-01-31
JP5468068B2 (ja) 2014-04-09
EA201001889A1 (ru) 2011-08-30
AR072200A1 (es) 2010-08-11
IL229560A (en) 2015-07-30
PL2307389T3 (pl) 2013-05-31
MY157518A (en) 2016-06-15
EP2307389A1 (en) 2011-04-13
CL2010001471A1 (es) 2011-05-06
CU20100252A7 (es) 2011-11-15
KR20110019781A (ko) 2011-02-28
BRPI0914231A2 (pt) 2015-11-03
US8158618B2 (en) 2012-04-17
DK2307389T3 (da) 2013-04-02
SV2010003769A (es) 2011-05-20
HRP20130234T1 (hr) 2013-04-30
CN102131791A (zh) 2011-07-20
ECSP10010698A (es) 2011-01-31
JP2014098006A (ja) 2014-05-29
IL210081A0 (en) 2011-02-28
US20110160184A1 (en) 2011-06-30
CU23884B1 (es) 2013-04-19
TWI488854B (zh) 2015-06-21
AU2009260905B2 (en) 2012-08-23
CY1113845T1 (el) 2016-07-27
AU2009260905A1 (en) 2009-12-23
NZ590616A (en) 2012-09-28
ZA201100488B (en) 2011-10-26
MX2010014203A (es) 2011-02-22
JP2011524898A (ja) 2011-09-08
PT2307389E (pt) 2013-03-28
US8653257B2 (en) 2014-02-18
SI2307389T1 (sl) 2013-04-30
RS52703B (sr) 2013-08-30
IL210081A (en) 2013-12-31
HK1156308A1 (en) 2012-06-08
CN102131791B (zh) 2014-12-24
CA2728675A1 (en) 2009-12-23
ME01516B (me) 2014-04-20

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