HK1198657A1 - Addition of iron to improve cell culture - Google Patents

Addition of iron to improve cell culture Download PDF

Info

Publication number: HK1198657A1
Authority: HK; Hong Kong
Prior art keywords: cell; cell culture; iron; composition; protein
Prior art date: 2011-10-21

Application number

HK14112182.7A

Other languages

English (en)

Chinese (zh)

Inventor

．王

W.王

．欒

Y-T．栾

．德拉波

D．德拉波

．諾蘭

R．P．诺兰

Original Assignee

辉瑞公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-21

Filing date

2012-10-09

Publication date

2015-05-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47324213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1198657(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-10-09 Application filed by 辉瑞公司 filed Critical 辉瑞公司

2015-05-22 Publication of HK1198657A1 publication Critical patent/HK1198657A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Cell Biology (AREA)
Reproductive Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Molecular Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

HK14112182.7A 2011-10-21 2012-10-09 Addition of iron to improve cell culture HK1198657A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161550058P	2011-10-21	2011-10-21
US61/550,058		2011-10-21
PCT/IB2012/055457 WO2013057628A1 (en)	2011-10-21	2012-10-09	Addition of iron to improve cell culture

Publications (1)

Publication Number	Publication Date
HK1198657A1 true HK1198657A1 (en)	2015-05-22

Family

ID=47324213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK14112182.7A HK1198657A1 (en)	2011-10-21	2012-10-09	Addition of iron to improve cell culture

Country Status (17)

Country	Link
US (1)	US20140322758A1 (ja)
EP (1)	EP2768944B2 (ja)
JP (1)	JP6400473B2 (ja)
KR (2)	KR20170021919A (ja)
CN (1)	CN103890166A (ja)
AU (1)	AU2012324495B2 (ja)
BR (1)	BR112014009379A2 (ja)
CA (1)	CA2852021C (ja)
DK (1)	DK2768944T3 (ja)
ES (1)	ES2784146T5 (ja)
HK (1)	HK1198657A1 (ja)
IL (1)	IL232171B (ja)
MX (1)	MX351991B (ja)
RU (1)	RU2663794C2 (ja)
SG (2)	SG10201702454YA (ja)
WO (1)	WO2013057628A1 (ja)
ZA (1)	ZA201402490B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG11201908891YA (en)	2017-03-31	2019-10-30	Boehringer Ingelheim Int	Perfusion medium
WO2022204120A1 (en) *	2021-03-23	2022-09-29	Biogen Ma Inc.	Reducing host cell impurities during recombinant protein production
EP4368698A1 (en) *	2022-11-09	2024-05-15	Sciperio, Inc.	Optimized cell culture medium utilizing iron (iii) citrate as an iron delivery method for the in vitro, bioreactor-centric production of manufactured blood
KR102701166B1 (ko) *	2023-12-01	2024-09-02	주식회사 한풍네이처팜	코리네박테리움 글루타미쿰 Hemo-P1 균주를 이용한 헴철 생산 방법

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4399216A (en)	1980-02-25	1983-08-16	The Trustees Of Columbia University	Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4522811A (en)	1982-07-08	1985-06-11	Syntex (U.S.A.) Inc.	Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
AU2353384A (en)	1983-01-19	1984-07-26	Genentech Inc.	Amplification in eukaryotic host cells
US4713339A (en)	1983-01-19	1987-12-15	Genentech, Inc.	Polycistronic expression vector construction
GB8308235D0 (en)	1983-03-25	1983-05-05	Celltech Ltd	Polypeptides
US4816567A (en)	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
JPS6147500A (ja)	1984-08-15	1986-03-07	Res Dev Corp Of Japan	キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en)	1984-08-27	1987-11-25	The Board Of Trustees Of The Leland Stanford Junior University	Chimeric receptors by dna splicing and expression
GB8422238D0 (en)	1984-09-03	1984-10-10	Neuberger M S	Chimeric proteins
GB8607679D0 (en)	1986-03-27	1986-04-30	Winter G P	Recombinant dna product
US5166320A (en)	1987-04-22	1992-11-24	University Of Connecticut	Carrier system and method for the introduction of genes into mammalian cells
US6291159B1 (en)	1989-05-16	2001-09-18	Scripps Research Institute	Method for producing polymers having a preselected activity
JPH0396383A (ja)	1989-09-08	1991-04-22	Riso Kagaku Corp	画像形成装置
EP0417563B1 (de)	1989-09-12	2000-07-05	F. Hoffmann-La Roche Ag	TNF-bindende Proteine
KR0185192B1 (ko)	1989-10-05	1999-04-01	제임스 더블유. 데이비	신규의 유전자 및 폴리펩티드의 무세포 합성 및 분리
US6657103B1 (en)	1990-01-12	2003-12-02	Abgenix, Inc.	Human antibodies derived from immunized xenomice
GB9021679D0 (en)	1990-10-05	1990-11-21	Gorman Scott David	Antibody preparation
GB9022545D0 (en)	1990-10-17	1990-11-28	Wellcome Found	Culture medium
DE4115722A1 (de) *	1991-05-14	1992-11-19	Boehringer Mannheim Gmbh	Serumfreies medium zur kultivierung von saeugerzellen
CA2111984A1 (en) *	1991-06-21	1993-01-07	Peter B. Suhr-Jessen	Iron chelate culture medium additive
GB9215834D0 (en)	1992-07-24	1992-09-09	Celltech Ltd	Cell culture
US6310185B1 (en)	1994-03-08	2001-10-30	Memorial Sloan Kettering Cancer Center	Recombinant human anti-Lewis Y antibodies
JP2000517188A (ja) *	1996-08-30	2000-12-26	ライフテクノロジーズ，インコーポレイテッド	無血清哺乳動物細胞培養培地およびその使用
TWI329129B (en)	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
KR20040094709A (ko)	2002-02-21	2004-11-10	와이어쓰	폴리스타틴 도메인을 포함하는 단백질
BR0307871A (pt)	2002-02-21	2005-04-12	Wyeth Corp	Proteìnas contendo domìnio de folistatina
ES2593304T3 (es)	2002-05-02	2016-12-07	Wyeth Holdings Llc	Conjugados de transportador derivado de caliqueamicina
AR047392A1 (es)	2002-10-22	2006-01-18	Wyeth Corp	Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
US20040223966A1 (en)	2002-10-25	2004-11-11	Wolfman Neil M.	ActRIIB fusion polypeptides and uses therefor
EP1664283A4 (en)	2003-09-18	2007-12-26	Raven Biotechnologies Inc	CELL CULTURE MEDIA
US7300773B2 (en)	2004-08-27	2007-11-27	Wyeth Research Ireland Limited	Production of TNFR-Ig
WO2006047380A2 (en)	2004-10-22	2006-05-04	Amgen, Inc.	Method and media for single cell serum-fee culture of cho cells
MX2007005210A (es) *	2004-11-02	2007-05-11	Ares Trading Sa	Medio de cultivo de celula libre de suero para las celulas de los mamiferos.
US20070190057A1 (en)	2006-01-23	2007-08-16	Jian Wu	Methods for modulating mannose content of recombinant proteins
CA2842964A1 (en) *	2006-09-13	2008-03-20	Abbvie Inc.	Cell culture improvements
CA2707524C (en)	2008-01-09	2016-04-12	Cellca Gmbh	Improved culture media additive and process for using it
DK2331678T3 (en) *	2008-06-13	2015-10-12	Janssen Biotech Inc	PROCEDURES FOR Gaining High-Viable Cell Density in Mammalian Cell Culture
CN102021139A (zh) *	2009-09-11	2011-04-20	华东理工大学	一种中国仓鼠卵巢细胞培养基及其制备方法和应用

2012
- 2012-10-09 DK DK12798373.2T patent/DK2768944T3/da active
- 2012-10-09 SG SG10201702454YA patent/SG10201702454YA/en unknown
- 2012-10-09 KR KR1020177004721A patent/KR20170021919A/ko not_active Ceased
- 2012-10-09 HK HK14112182.7A patent/HK1198657A1/xx unknown
- 2012-10-09 BR BR112014009379A patent/BR112014009379A2/pt not_active Application Discontinuation
- 2012-10-09 KR KR1020147013456A patent/KR20140077977A/ko not_active Ceased
- 2012-10-09 EP EP12798373.2A patent/EP2768944B2/en active Active
- 2012-10-09 CN CN201280051721.4A patent/CN103890166A/zh active Pending
- 2012-10-09 CA CA2852021A patent/CA2852021C/en active Active
- 2012-10-09 SG SG11201401220SA patent/SG11201401220SA/en unknown
- 2012-10-09 MX MX2014004735A patent/MX351991B/es active IP Right Grant
- 2012-10-09 WO PCT/IB2012/055457 patent/WO2013057628A1/en not_active Ceased
- 2012-10-09 JP JP2014536367A patent/JP6400473B2/ja not_active Expired - Fee Related
- 2012-10-09 RU RU2014115731A patent/RU2663794C2/ru active
- 2012-10-09 ES ES12798373T patent/ES2784146T5/es active Active
- 2012-10-09 US US14/352,740 patent/US20140322758A1/en not_active Abandoned
- 2012-10-09 AU AU2012324495A patent/AU2012324495B2/en not_active Ceased
2014
- 2014-04-04 ZA ZA2014/02490A patent/ZA201402490B/en unknown
- 2014-04-22 IL IL232171A patent/IL232171B/en active IP Right Grant

Also Published As

Publication number	Publication date
EP2768944B1 (en)	2020-02-26
ZA201402490B (en)	2015-11-25
EP2768944B2 (en)	2023-11-22
JP2014530620A (ja)	2014-11-20
IL232171B (en)	2018-07-31
CA2852021A1 (en)	2013-04-25
MX2014004735A (es)	2014-07-28
ES2784146T5 (es)	2024-06-04
ES2784146T3 (es)	2020-09-22
AU2012324495B2 (en)	2016-04-21
SG11201401220SA (en)	2014-07-30
CN103890166A (zh)	2014-06-25
AU2012324495A1 (en)	2014-04-24
DK2768944T3 (da)	2020-04-20
JP6400473B2 (ja)	2018-10-03
RU2014115731A (ru)	2015-11-27
CA2852021C (en)	2018-08-28
MX351991B (es)	2017-11-03
IL232171A0 (en)	2014-06-30
BR112014009379A2 (pt)	2017-04-18
WO2013057628A1 (en)	2013-04-25
KR20170021919A (ko)	2017-02-28
US20140322758A1 (en)	2014-10-30
SG10201702454YA (en)	2017-05-30
RU2663794C2 (ru)	2018-08-09
EP2768944A1 (en)	2014-08-27
KR20140077977A (ko)	2014-06-24

Publication	Publication Date	Title
JP5921910B2 (ja)	2016-05-24	ＴＮＦＲ−Ｉｇ融合タンパク質の製法
KR101540124B1 (ko)	2015-07-28	항노화 화합물을 사용하는 단백질의 생산 방법
JP4864892B2 (ja)	2012-02-01	ポリペプチドの製造
JP2015133980A (ja)	2015-07-27	抗アミロイドベータ抗体の製法
US20230416674A1 (en)	2023-12-28	Cell culture process
CA2852021C (en)	2018-08-28	Addition of iron to improve cell culture
US20130150554A1 (en)	2013-06-13	Cell culture of growth factor-free adapted cells
WO2021090888A1 (ja)	2021-05-14	タンパク質の製造方法
HK40002727A (zh)	2020-03-27	细胞培养工艺