[go: up one dir, main page]

MX2014004735A - Adicion de hierro para mejorar cultivo celular. - Google Patents

Adicion de hierro para mejorar cultivo celular.

Info

Publication number
MX2014004735A
MX2014004735A MX2014004735A MX2014004735A MX2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A MX 2014004735 A MX2014004735 A MX 2014004735A
Authority
MX
Mexico
Prior art keywords
cell culture
iron
addition
improve cell
titer
Prior art date
Application number
MX2014004735A
Other languages
English (en)
Other versions
MX351991B (es
Inventor
Wenge Wang
Yen-Tung Luan
Denis Drapeau
Ryan P Nolan
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47324213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014004735(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of MX2014004735A publication Critical patent/MX2014004735A/es
Publication of MX351991B publication Critical patent/MX351991B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención proporciona, entre otras cosas, métodos para incrementar la densidad celular, viabilidad y/o titulación en un cultivo celular que incluye las etapas de adicionar una composición que comprende hierro al cultivo celular.
MX2014004735A 2011-10-21 2012-10-09 Adicion de hierro para mejorar cultivo celular. MX351991B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161550058P 2011-10-21 2011-10-21
PCT/IB2012/055457 WO2013057628A1 (en) 2011-10-21 2012-10-09 Addition of iron to improve cell culture

Publications (2)

Publication Number Publication Date
MX2014004735A true MX2014004735A (es) 2014-07-28
MX351991B MX351991B (es) 2017-11-03

Family

ID=47324213

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014004735A MX351991B (es) 2011-10-21 2012-10-09 Adicion de hierro para mejorar cultivo celular.

Country Status (17)

Country Link
US (1) US20140322758A1 (es)
EP (1) EP2768944B2 (es)
JP (1) JP6400473B2 (es)
KR (2) KR20140077977A (es)
CN (1) CN103890166A (es)
AU (1) AU2012324495B2 (es)
BR (1) BR112014009379A2 (es)
CA (1) CA2852021C (es)
DK (1) DK2768944T3 (es)
ES (1) ES2784146T5 (es)
HK (1) HK1198657A1 (es)
IL (1) IL232171B (es)
MX (1) MX351991B (es)
RU (1) RU2663794C2 (es)
SG (2) SG11201401220SA (es)
WO (1) WO2013057628A1 (es)
ZA (1) ZA201402490B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102604992B1 (ko) * 2017-03-31 2023-11-24 베링거 인겔하임 인터내셔날 게엠베하 관류 배지
US20240150723A1 (en) * 2021-03-23 2024-05-09 Biogen Ma Inc. Reducing host cell impurities during recombinant protein production
EP4368698A1 (en) * 2022-11-09 2024-05-15 Sciperio, Inc. Optimized cell culture medium utilizing iron (iii) citrate as an iron delivery method for the in vitro, bioreactor-centric production of manufactured blood
KR102701166B1 (ko) * 2023-12-01 2024-09-02 주식회사 한풍네이처팜 코리네박테리움 글루타미쿰 Hemo-P1 균주를 이용한 헴철 생산 방법

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
AU2353384A (en) 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5166320A (en) 1987-04-22 1992-11-24 University Of Connecticut Carrier system and method for the introduction of genes into mammalian cells
US6291159B1 (en) 1989-05-16 2001-09-18 Scripps Research Institute Method for producing polymers having a preselected activity
JPH0396383A (ja) 1989-09-08 1991-04-22 Riso Kagaku Corp 画像形成装置
DE59010908D1 (de) 1989-09-12 2000-08-10 Hoffmann La Roche TNF-bindende Proteine
EP0494955B1 (en) 1989-10-05 1998-07-15 Optein, Inc. Cell-free synthesis and isolation of novel genes and polypeptides
US6657103B1 (en) 1990-01-12 2003-12-02 Abgenix, Inc. Human antibodies derived from immunized xenomice
GB9021679D0 (en) 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
DE4115722A1 (de) * 1991-05-14 1992-11-19 Boehringer Mannheim Gmbh Serumfreies medium zur kultivierung von saeugerzellen
CA2111984A1 (en) * 1991-06-21 1993-01-07 Peter B. Suhr-Jessen Iron chelate culture medium additive
GB9215834D0 (en) 1992-07-24 1992-09-09 Celltech Ltd Cell culture
US6310185B1 (en) 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies
EP1482031B1 (en) * 1996-08-30 2015-10-28 Life Technologies Corporation Serum-free mammalian cell culture medium, and uses thereof
TW200526779A (en) 2001-02-08 2005-08-16 Wyeth Corp Modified and stabilized GDF propeptides and uses thereof
AU2003217612A1 (en) 2002-02-21 2003-09-09 Wyeth GASP1: a follistatin domain containing protein
WO2003072714A2 (en) 2002-02-21 2003-09-04 Wyeth Follistatin domain containing proteins
HUE030806T2 (hu) 2002-05-02 2017-05-29 Wyeth Holdings Llc Calicheamicin származék-hordozó konjugátumok
US7261893B2 (en) 2002-10-22 2007-08-28 Wyeth Neutralizing antibodies against GDF-8 and uses therefor
US20040223966A1 (en) 2002-10-25 2004-11-11 Wolfman Neil M. ActRIIB fusion polypeptides and uses therefor
US7462487B2 (en) 2003-09-18 2008-12-09 Raven Biotechnologies, Inc. Cell culture media
TWI364458B (en) * 2004-08-27 2012-05-21 Wyeth Res Ireland Ltd Production of tnfr-lg
US20060115901A1 (en) 2004-10-22 2006-06-01 Bahram Valamehr Method and media for single cell serum-free culture of CHO cells
NZ554131A (en) * 2004-11-02 2009-08-28 Ares Trading Sa Serum-free cell culture medium for mammalian cells
US20070190057A1 (en) 2006-01-23 2007-08-16 Jian Wu Methods for modulating mannose content of recombinant proteins
RU2518289C2 (ru) 2006-09-13 2014-06-10 Эббви Инк, Способ получения антитела или его фрагмента с подпиткой (варианты)
KR101594046B1 (ko) * 2008-01-09 2016-02-15 첼카 게엠베하 개선된 배양 배지 첨가제 및 이를 이용한 방법
EP2331678B1 (en) * 2008-06-13 2015-09-30 Janssen Biotech, Inc. Methods for obtaining high viable cell density in mammalian cell culture
CN102021139A (zh) * 2009-09-11 2011-04-20 华东理工大学 一种中国仓鼠卵巢细胞培养基及其制备方法和应用

Also Published As

Publication number Publication date
EP2768944B1 (en) 2020-02-26
MX351991B (es) 2017-11-03
HK1198657A1 (en) 2015-05-22
IL232171B (en) 2018-07-31
BR112014009379A2 (pt) 2017-04-18
RU2663794C2 (ru) 2018-08-09
SG11201401220SA (en) 2014-07-30
CA2852021C (en) 2018-08-28
AU2012324495A1 (en) 2014-04-24
CN103890166A (zh) 2014-06-25
ZA201402490B (en) 2015-11-25
CA2852021A1 (en) 2013-04-25
AU2012324495B2 (en) 2016-04-21
ES2784146T5 (es) 2024-06-04
WO2013057628A1 (en) 2013-04-25
US20140322758A1 (en) 2014-10-30
IL232171A0 (en) 2014-06-30
DK2768944T3 (da) 2020-04-20
EP2768944B2 (en) 2023-11-22
SG10201702454YA (en) 2017-05-30
EP2768944A1 (en) 2014-08-27
RU2014115731A (ru) 2015-11-27
KR20170021919A (ko) 2017-02-28
JP6400473B2 (ja) 2018-10-03
JP2014530620A (ja) 2014-11-20
KR20140077977A (ko) 2014-06-24
ES2784146T3 (es) 2020-09-22

Similar Documents

Publication Publication Date Title
IL273159A (en) A culture medium preparation, and a method for culturing cells or tissues by using the preparation
WO2013096709A3 (en) Methods of increasing the viability or longevity of an organ or organ explant
MX2013008903A (es) Metodos de desarrollo de variantes de terpeno sintasa.
PH12014501427B1 (en) Anti-phf-tau antibodies and their uses
MX2013001045A (es) Organoide hepatico, sus usos y metodo de cultivo para obtenerlos.
NZ704719A (en) Cd133 aptamers for detection of cancer stem cells
EP2920293A4 (en) MICROBIAL STRAINS, COMPOSITIONS AND METHODS FOR EXPANDING THE PHOSPHATE AVAILABLE FOR PLANTS
IN2015DN00636A (es)
WO2011158125A3 (en) Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
IL229176B (en) Cryopreserved, thawed and reactivated t cell containing compositions, methods of producing same and use of same in immunotherapy”
MX2013004981A (es) Composiciones y metodos para la administracion de agentes terapeuticos.
PH12014501019A1 (en) Kit comprising serum replacement and labile factors
WO2012102527A3 (ko) 조절자 Ｔ 세포에 특이적으로 존재하는 새로운 표면단백질 Ｌｒｉｇ-1의 용도
WO2012096461A3 (ko) 줄기세포의 부유배양용 조성물
MX366112B (es) Medio de cultivo celular y metodos de produccion de anticuerpos.
IN2014DN03298A (es)
MX358132B (es) Solucion de trombina y metodos de uso de esta.
MX351991B (es) Adicion de hierro para mejorar cultivo celular.
EP2748326A4 (en) IMPROVED COMPOSITIONS AND METHODS FOR BIOSYNTHESIS OF 1-ALKENEN IN MANIPULATED MICROORGANISMS
WO2012106089A3 (en) 3d cell viability assay
MX2013014390A (es) Metodos, composiciones y kits para la determinacion del virus de la hepatitis a.
PH12012501547A1 (en) Methods of preparing thiazolidines
UA73278U (ru) Спирт коньячный выдержанный
IN2012DE02590A (es)
AU336400S (en) Vibration Isolator

Legal Events

Date Code Title Description
FG Grant or registration