GT200400148A - Tienoimidazoles sustituidos, procedimiento para su preparacion, su uso como un medicamento o adyuvante de diagnostico y medicamento que los comprende. - Google Patents
Tienoimidazoles sustituidos, procedimiento para su preparacion, su uso como un medicamento o adyuvante de diagnostico y medicamento que los comprende.Info
- Publication number
- GT200400148A GT200400148A GT200400148A GT200400148A GT200400148A GT 200400148 A GT200400148 A GT 200400148A GT 200400148 A GT200400148 A GT 200400148A GT 200400148 A GT200400148 A GT 200400148A GT 200400148 A GT200400148 A GT 200400148A
- Authority
- GT
- Guatemala
- Prior art keywords
- tienoimidazoles
- understands
- adjuster
- medication
- medicinal
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A COMPUESTOS DE LAS FÓRMULAS GENERALES I Y II EN LA QUE R1,R2,R3,R4, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON DE UTILIDAD EN UNA AMPLIA VARIEDAD DE PATOLOGÍAS TALES COMO TRASTORNOS DEL APARATO RESPIRATORIO, SISTEMA NERVIOSO CENTRAL ENTRE OTROS, DESCRITOS EN EL EXPEDIENTE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10341240A DE10341240A1 (de) | 2003-09-08 | 2003-09-08 | Substituierte Thienoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200400148A true GT200400148A (es) | 2007-03-22 |
Family
ID=34258478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200400148A GT200400148A (es) | 2003-09-08 | 2004-08-02 | Tienoimidazoles sustituidos, procedimiento para su preparacion, su uso como un medicamento o adyuvante de diagnostico y medicamento que los comprende. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7179830B2 (es) |
| EP (1) | EP1664058B1 (es) |
| JP (1) | JP2007505035A (es) |
| KR (1) | KR20060069489A (es) |
| CN (1) | CN1845926A (es) |
| AR (1) | AR045600A1 (es) |
| AT (1) | ATE378343T1 (es) |
| AU (1) | AU2004272225A1 (es) |
| BR (1) | BRPI0414191A (es) |
| CA (1) | CA2537695A1 (es) |
| DE (2) | DE10341240A1 (es) |
| GT (1) | GT200400148A (es) |
| IL (1) | IL173918A0 (es) |
| MA (1) | MA28026A1 (es) |
| MX (1) | MXPA06001830A (es) |
| NO (1) | NO20061559L (es) |
| PA (1) | PA8611401A1 (es) |
| PE (1) | PE20050571A1 (es) |
| RU (1) | RU2006111467A (es) |
| SV (1) | SV2005001872A (es) |
| TW (1) | TW200521130A (es) |
| WO (1) | WO2005026173A1 (es) |
| ZA (1) | ZA200601001B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2804574T3 (es) | 2008-05-09 | 2021-02-08 | Merck Patent Gmbh | Composición farmacéutica para tratar enfermedades asociadas con la resistencia a la insulina y la disfunción de células beta |
| FR2993780B1 (fr) * | 2012-07-26 | 2015-02-13 | Assist Publ Hopitaux De Paris | Methode de traitement de la sclerose en plaque |
| CN102964354B (zh) * | 2012-11-16 | 2014-08-13 | 江苏先声药业有限公司 | 一类噻吩并咪唑衍生物及其应用 |
| ES2738693T3 (es) * | 2014-04-17 | 2020-01-24 | Pasteur Institut Korea | Compuestos para el tratamiento de infecciones virales |
| EP3173408B1 (en) | 2014-07-25 | 2018-11-21 | Taisho Pharmaceutical Co., Ltd. | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE754935A (fr) | 1969-08-13 | 1971-02-17 | Hoechst Ag | 2-(thienyl-3'-amino)-1,3-diazacycloalcenes et leur preparation |
| AU636066B2 (en) * | 1990-10-30 | 1993-04-08 | Takeda Chemical Industries Ltd. | Thienoimidazole derivatives, their production and use |
| DE4034728A1 (de) * | 1990-10-30 | 1992-05-07 | Schering Ag | Neue thienoimidazolderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
| DE19633966A1 (de) | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19945302A1 (de) | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenylderivate als NHE-3-Inhibitoren |
| DE10015248A1 (de) | 2000-03-28 | 2001-10-04 | Merck Patent Gmbh | Bisamidino-Verbindungen als NHE-3 Inhibitoren |
| DE10019062A1 (de) | 2000-04-18 | 2001-10-25 | Merck Patent Gmbh | 2-Guanidino-4-aryl-chinazoline als NHE-3 Inhibitoren |
| DE10060292A1 (de) * | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Verwendung substituierter Benzimidazole zur Herstellung eines Medikaments zur Behandlung von Krankheiten, welche durch Inhibierung des Na+/H+-Austauschers beeinflusst werden können und sie enthaltendes Medikament |
| DE10163239A1 (de) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituierte Imidazolidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie enthaltendes Medikament |
-
2003
- 2003-09-08 DE DE10341240A patent/DE10341240A1/de not_active Withdrawn
-
2004
- 2004-08-02 GT GT200400148A patent/GT200400148A/es unknown
- 2004-08-25 US US10/926,118 patent/US7179830B2/en not_active Expired - Fee Related
- 2004-09-02 PE PE2004000847A patent/PE20050571A1/es not_active Application Discontinuation
- 2004-09-03 CN CNA2004800256563A patent/CN1845926A/zh active Pending
- 2004-09-03 DE DE502004005522T patent/DE502004005522D1/de not_active Expired - Lifetime
- 2004-09-03 AU AU2004272225A patent/AU2004272225A1/en not_active Abandoned
- 2004-09-03 EP EP04764791A patent/EP1664058B1/de not_active Expired - Lifetime
- 2004-09-03 CA CA002537695A patent/CA2537695A1/en not_active Abandoned
- 2004-09-03 BR BRPI0414191-1A patent/BRPI0414191A/pt not_active Application Discontinuation
- 2004-09-03 RU RU2006111467/04A patent/RU2006111467A/ru not_active Application Discontinuation
- 2004-09-03 WO PCT/EP2004/009836 patent/WO2005026173A1/de not_active Ceased
- 2004-09-03 KR KR1020067004685A patent/KR20060069489A/ko not_active Withdrawn
- 2004-09-03 AT AT04764791T patent/ATE378343T1/de not_active IP Right Cessation
- 2004-09-03 JP JP2006525114A patent/JP2007505035A/ja active Pending
- 2004-09-03 MX MXPA06001830A patent/MXPA06001830A/es not_active Application Discontinuation
- 2004-09-06 TW TW093126816A patent/TW200521130A/zh unknown
- 2004-09-06 AR ARP040103198A patent/AR045600A1/es unknown
- 2004-09-08 SV SV2004001872A patent/SV2005001872A/es not_active Application Discontinuation
- 2004-09-08 PA PA20048611401A patent/PA8611401A1/es unknown
-
2006
- 2006-02-03 ZA ZA200601001A patent/ZA200601001B/xx unknown
- 2006-02-23 IL IL173918A patent/IL173918A0/en unknown
- 2006-03-06 MA MA28857A patent/MA28026A1/fr unknown
- 2006-04-06 NO NO20061559A patent/NO20061559L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007505035A (ja) | 2007-03-08 |
| ZA200601001B (en) | 2007-03-28 |
| KR20060069489A (ko) | 2006-06-21 |
| ATE378343T1 (de) | 2007-11-15 |
| MXPA06001830A (es) | 2006-05-31 |
| CN1845926A (zh) | 2006-10-11 |
| TW200521130A (en) | 2005-07-01 |
| IL173918A0 (en) | 2006-07-05 |
| US20050075385A1 (en) | 2005-04-07 |
| DE502004005522D1 (de) | 2007-12-27 |
| AR045600A1 (es) | 2005-11-02 |
| MA28026A1 (fr) | 2006-07-03 |
| PE20050571A1 (es) | 2005-12-02 |
| NO20061559L (no) | 2006-04-06 |
| SV2005001872A (es) | 2005-03-09 |
| CA2537695A1 (en) | 2005-03-24 |
| US7179830B2 (en) | 2007-02-20 |
| DE10341240A1 (de) | 2005-04-07 |
| AU2004272225A1 (en) | 2005-03-24 |
| EP1664058B1 (de) | 2007-11-14 |
| BRPI0414191A (pt) | 2006-10-31 |
| PA8611401A1 (es) | 2005-03-28 |
| RU2006111467A (ru) | 2006-08-10 |
| EP1664058A1 (de) | 2006-06-07 |
| WO2005026173A1 (de) | 2005-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CU23464B7 (es) | (1,8)naftidirin-2-onas y compuestos relacionados para el tratamiento de la esquizofrenia | |
| UY31748A (es) | Nuevos compuestos para el tratamiento de trastornos del snc (sistema nervioso central) | |
| GT200600159A (es) | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
| UY28876A1 (es) | Compuestos de morfolina sustituida y composiciones para el tratamiento de trastornos del sistema nervioso central | |
| ECSP045473A (es) | Derivados de 1-(aminoalquil)-3-sulfonilindol y 1-aminoalquil-3-sulfonilindazol como ligandos de 5-hidroxitriptamina-6 | |
| PA8675701A1 (es) | Nuevos derivados del fluoreno, composiciones que los contienen y su utilización | |
| PA8615701A1 (es) | Derivados de dihidrobenzofuranilo alcanamina y metodos para su uso. | |
| UY27427A1 (es) | Nuevas dihidro-pteridinonas, procedimientos para su preparación y su utilización como medicamentos | |
| UY29829A1 (es) | Derivados de fenil-1,2,4-oxadiazolona con grupo fenilo, procedimiento para su preparación y su uso como productos farmacéuticos. | |
| ECSP055535A (es) | Derivados de 1-heterociclialquil-3-sulfonilazaindol o azaindol como ligandos de 5-hidroxitriptamina-6 | |
| GT199800046A (es) | Compuestos de pirazina. | |
| CR10062A (es) | Composiciones y metodos de tratamiento para trastornos del sistema nervioso central | |
| CR10020A (es) | Antagonistas de los receptores 2 de dopamina de rapida disociación | |
| CL2008000806A1 (es) | Compuestos derivados de aza piridopirimidinona, con actividad agonista de hm74a; procedimiento de preparacion de dichos compuestos; composicion farmaceutico que las comprende; y su uso para preparar medicamentos para el tratamiento de enferemedades ateroscleroticas, dislipidemias, alzheimer, diabetes, entre otras. | |
| UY29796A1 (es) | Nuevos compuestos para el tratamiento de trastornos neurológicos, psiquiátricos o del dolor | |
| ECSP088366A (es) | 1,2-diarilimidazoles para uso como moduladores de cb1 | |
| CL2008002247A1 (es) | Compuestos derivados de fenil amida; proceso de preparacion; composicion farmaceutica que los contiene; y su uso en la preparacion de medicamentos para el tratamiento de trastornos del sueno, narcolepsia y trastornos psiquiatricos, entre otros. | |
| CL2008001820A1 (es) | Compuestos derivados de aril-isoxasol-imidazol; procedimiento de preparacion; composicion farmaceutica que los contiene; y uso en la preparacion de medicamentos utiles en el tratamiento de trastornos cognitivos y enfermedades relacionadas con alzheimer. | |
| ECSP088250A (es) | Derivados de pirazol como agentes terapéuticos | |
| CR9407A (es) | Tetrahidropiridoazepin-8-onas y compuestos relacionados para el tratamiento de la esquizofrenia | |
| GT200600161A (es) | Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de los trastornos psicoticos | |
| UY29831A1 (es) | Derivados de fenil-1,2,4-oxadiazolona, procesos para su preparación y su uso como compuestos farmacéuticos. | |
| CL2011000184A1 (es) | Compuestos derivados de 1,6-dihidro-2h-3-oxa-6-aza-as-indaceno; agonista de receptores de melatonina; proceso para la preparacion de los compuestos; composicion farmaceutica que comprende a los compuestos; y su uso de los compuestos en la preparacion de medicamentos. | |
| GT200400148A (es) | Tienoimidazoles sustituidos, procedimiento para su preparacion, su uso como un medicamento o adyuvante de diagnostico y medicamento que los comprende. | |
| GT200100197A (es) | Derivados de triptamina y compuestos analogos, y formulaciones farmaceuticas que lo contienen. |