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GT200400146A - Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso - Google Patents

Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso

Info

Publication number
GT200400146A
GT200400146A GT200400146A GT200400146A GT200400146A GT 200400146 A GT200400146 A GT 200400146A GT 200400146 A GT200400146 A GT 200400146A GT 200400146 A GT200400146 A GT 200400146A GT 200400146 A GT200400146 A GT 200400146A
Authority
GT
Guatemala
Prior art keywords
benzoisotiazol
tiazol
dioxide
procedure
preparation
Prior art date
Application number
GT200400146A
Other languages
English (en)
Inventor
Stefan Petry
Karl-Heinz Baringhaus
Norbert Tennagels
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200400146A publication Critical patent/GT200400146A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCIÒN SE REFIERE A COMPUESTOS DE LA FÒRMULA GENERAL I EN LA QUE R1,R2,R3,R4,R5,R6, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS TIENEN UN EFECTO HIPOGLUCEMIANTE POR LO QUE SON DE UTILIDAD EN CUADROS DE DIABETES.
GT200400146A 2003-07-28 2004-07-23 Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso GT200400146A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10334309A DE10334309A1 (de) 2003-07-28 2003-07-28 Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
GT200400146A true GT200400146A (es) 2005-08-12

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200400146A GT200400146A (es) 2003-07-28 2004-07-23 Derivados sustituidos del dioxido de tiazol-benzoisotiazol, procedimiento para su preparacion y su uso

Country Status (37)

Country Link
EP (1) EP1651644B1 (es)
JP (1) JP2007500145A (es)
KR (1) KR20060052886A (es)
CN (1) CN100413862C (es)
AR (1) AR045113A1 (es)
AT (1) ATE346065T1 (es)
AU (1) AU2004261370B2 (es)
BR (1) BRPI0412997A (es)
CA (1) CA2533673A1 (es)
CR (1) CR8202A (es)
CY (1) CY1105962T1 (es)
DE (2) DE10334309A1 (es)
DK (1) DK1651644T3 (es)
EC (1) ECSP066326A (es)
ES (1) ES2276319T3 (es)
GT (1) GT200400146A (es)
IL (1) IL173289A0 (es)
JO (1) JO2449B1 (es)
MA (1) MA27932A1 (es)
MY (1) MY141197A (es)
NO (1) NO20060908L (es)
NZ (1) NZ544975A (es)
OA (1) OA13198A (es)
PA (1) PA8607201A1 (es)
PE (1) PE20050326A1 (es)
PL (1) PL1651644T3 (es)
PT (1) PT1651644E (es)
RS (1) RS20060015A (es)
RU (1) RU2350613C2 (es)
SA (1) SA04250332B1 (es)
SI (1) SI1651644T1 (es)
TN (1) TNSN06030A1 (es)
TW (1) TW200524923A (es)
UA (1) UA83057C2 (es)
UY (1) UY28443A1 (es)
WO (1) WO2005012295A1 (es)
ZA (1) ZA200510378B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (de) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
AU2007245059B2 (en) 2006-03-31 2011-07-28 Novartis Ag New compounds
JP2010500300A (ja) 2006-08-08 2010-01-07 サノフィ−アベンティス アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2010003624A2 (en) 2008-07-09 2010-01-14 Sanofi-Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
KR20120060207A (ko) 2009-08-26 2012-06-11 사노피 신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120057A1 (de) 2011-03-08 2012-09-13 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683701B1 (de) 2011-03-08 2014-12-24 Sanofi Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de) 2011-03-08 2012-09-13 Sanofi Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2025017207A1 (en) * 2023-07-20 2025-01-23 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh Inhibitors of smndc1 and their therapeutic use

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* Cited by examiner, † Cited by third party
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US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (ja) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd アミノベンゾサルタム誘導体およびその用途
JP3856829B2 (ja) * 1995-06-02 2006-12-13 サノフィ−アベンティス オキサゾリジノン誘導体、その製造及び治療的使用
CO5190696A1 (es) * 1999-06-16 2002-08-29 Smithkline Beecham Corp Antagonistas de los receptores il-8
DE10038709A1 (de) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen

Also Published As

Publication number Publication date
ES2276319T3 (es) 2007-06-16
ECSP066326A (es) 2006-07-28
CN1829715A (zh) 2006-09-06
ZA200510378B (en) 2006-11-29
UY28443A1 (es) 2005-02-28
PL1651644T3 (pl) 2007-03-30
RS20060015A (sr) 2007-12-31
AU2004261370B2 (en) 2009-07-16
PT1651644E (pt) 2007-01-31
MA27932A1 (fr) 2006-06-01
CY1105962T1 (el) 2011-04-06
EP1651644A1 (de) 2006-05-03
NO20060908L (no) 2006-02-24
JO2449B1 (en) 2008-10-09
JP2007500145A (ja) 2007-01-11
CR8202A (es) 2008-10-15
IL173289A0 (en) 2006-06-11
SI1651644T1 (sl) 2007-02-28
PE20050326A1 (es) 2005-06-16
CA2533673A1 (en) 2005-02-10
DK1651644T3 (da) 2007-03-26
PA8607201A1 (es) 2005-03-03
AU2004261370A1 (en) 2005-02-10
TNSN06030A1 (en) 2007-10-03
WO2005012295A1 (de) 2005-02-10
EP1651644B1 (de) 2006-11-22
UA83057C2 (ru) 2008-06-10
CN100413862C (zh) 2008-08-27
RU2350613C2 (ru) 2009-03-27
ATE346065T1 (de) 2006-12-15
DE10334309A1 (de) 2005-03-03
HK1091825A1 (en) 2007-01-26
BRPI0412997A (pt) 2006-10-03
SA04250332B1 (ar) 2008-02-25
KR20060052886A (ko) 2006-05-19
NZ544975A (en) 2010-02-26
TW200524923A (en) 2005-08-01
MY141197A (en) 2010-03-31
DE502004002117D1 (de) 2007-01-04
RU2006106231A (ru) 2006-06-27
AR045113A1 (es) 2005-10-19
OA13198A (en) 2006-12-13

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