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TNSN06030A1 - Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same - Google Patents

Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same

Info

Publication number
TNSN06030A1
TNSN06030A1 TNP2006000030A TNSN06030A TNSN06030A1 TN SN06030 A1 TNSN06030 A1 TN SN06030A1 TN P2006000030 A TNP2006000030 A TN P2006000030A TN SN06030 A TNSN06030 A TN SN06030A TN SN06030 A1 TNSN06030 A1 TN SN06030A1
Authority
TN
Tunisia
Prior art keywords
derivavites
production
same
substituted thiazole
benzoisothiazole
Prior art date
Application number
TNP2006000030A
Other languages
French (fr)
Inventor
Karl-Heinz Baringhaus
Guenter Mueller
Stefan Petry
Norbert Tennagels
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of TNSN06030A1 publication Critical patent/TNSN06030A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

The invention relates to compounds of formula (I) wherein the radicals have the cited designations, and to the physiologically compatible salts thereof. Said compounds are suitable, for example, as medicaments for reducing blood sugar levels and for the prevention and treatment of diabetes.
TNP2006000030A 2003-07-28 2006-01-27 Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same TNSN06030A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10334309A DE10334309A1 (en) 2003-07-28 2003-07-28 Substituted thiazole-Benzoisothiazoldioxidderivate, processes for their preparation and their use
PCT/EP2004/007847 WO2005012295A1 (en) 2003-07-28 2004-07-15 Substituted thiazole-benzoisothiazole dioxide derivatives, method for the production thereof and use of the same

Publications (1)

Publication Number Publication Date
TNSN06030A1 true TNSN06030A1 (en) 2007-10-03

Family

ID=34111694

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2006000030A TNSN06030A1 (en) 2003-07-28 2006-01-27 Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same

Country Status (37)

Country Link
EP (1) EP1651644B1 (en)
JP (1) JP2007500145A (en)
KR (1) KR20060052886A (en)
CN (1) CN100413862C (en)
AR (1) AR045113A1 (en)
AT (1) ATE346065T1 (en)
AU (1) AU2004261370B2 (en)
BR (1) BRPI0412997A (en)
CA (1) CA2533673A1 (en)
CR (1) CR8202A (en)
CY (1) CY1105962T1 (en)
DE (2) DE10334309A1 (en)
DK (1) DK1651644T3 (en)
EC (1) ECSP066326A (en)
ES (1) ES2276319T3 (en)
GT (1) GT200400146A (en)
IL (1) IL173289A0 (en)
JO (1) JO2449B1 (en)
MA (1) MA27932A1 (en)
MY (1) MY141197A (en)
NO (1) NO20060908L (en)
NZ (1) NZ544975A (en)
OA (1) OA13198A (en)
PA (1) PA8607201A1 (en)
PE (1) PE20050326A1 (en)
PL (1) PL1651644T3 (en)
PT (1) PT1651644E (en)
RS (1) RS20060015A (en)
RU (1) RU2350613C2 (en)
SA (1) SA04250332B1 (en)
SI (1) SI1651644T1 (en)
TN (1) TNSN06030A1 (en)
TW (1) TW200524923A (en)
UA (1) UA83057C2 (en)
UY (1) UY28443A1 (en)
WO (1) WO2005012295A1 (en)
ZA (1) ZA200510378B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004026532A1 (en) * 2004-05-29 2006-01-05 Sanofi-Aventis Deutschland Gmbh Substituted Oxazole Benzoisothiazoldioxidderivate, process for their preparation and their use
EP2402318A1 (en) 2006-03-31 2012-01-04 Novartis AG DGAT inhibitors
BRPI0715160A2 (en) 2006-08-08 2013-06-11 Sanofi Aventis arylamimoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, drugs comprising these compounds, and their use
EP2025674A1 (en) 2007-08-15 2009-02-18 sanofi-aventis Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs
TW201014822A (en) 2008-07-09 2010-04-16 Sanofi Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
JP2013503135A (en) 2009-08-26 2013-01-31 サノフイ Novel crystalline heteroaromatic fluoroglycoside hydrate, pharmaceutical comprising the compound and use thereof
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
WO2011157827A1 (en) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
US8809324B2 (en) 2011-03-08 2014-08-19 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
EP2683701B1 (en) 2011-03-08 2014-12-24 Sanofi Oxathiazine derivatives substituted with benzyl or heteromethylene groups, method for their preparation, their usage as medicament, medicament containing same and its use
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
EP2683700B1 (en) 2011-03-08 2015-02-18 Sanofi Tetra-substituted oxathiazine derivatives, method for their preparation, their usage as medicament and medicament containing same and its use
WO2012120053A1 (en) 2011-03-08 2012-09-13 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2766349B1 (en) 2011-03-08 2016-06-01 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683703B1 (en) 2011-03-08 2015-05-27 Sanofi Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2025017207A1 (en) * 2023-07-20 2025-01-23 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh Inhibitors of smndc1 and their therapeutic use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539584A (en) * 1967-11-14 1970-11-10 Colgate Palmolive Co 5-substituted-2,1-benzisothiazolines
JPH04128276A (en) * 1990-09-19 1992-04-28 Pfizer Pharmaceut Co Ltd Aminobenzosultam derivative and its use
CA2223011C (en) * 1995-06-02 2007-01-09 Synthelabo Oxazolidinone derivatives, their preparation and therapeutical use
CO5190696A1 (en) * 1999-06-16 2002-08-29 Smithkline Beecham Corp ANTAGONISTS OF IL-8 RECEIVERS
DE10038709A1 (en) * 2000-08-09 2002-02-28 Aventis Pharma Gmbh Substituted and unsubstituted benzooxathiazoles and compounds derived from them

Also Published As

Publication number Publication date
EP1651644A1 (en) 2006-05-03
RS20060015A (en) 2007-12-31
CN1829715A (en) 2006-09-06
TW200524923A (en) 2005-08-01
BRPI0412997A (en) 2006-10-03
KR20060052886A (en) 2006-05-19
EP1651644B1 (en) 2006-11-22
SI1651644T1 (en) 2007-02-28
GT200400146A (en) 2005-08-12
OA13198A (en) 2006-12-13
UA83057C2 (en) 2008-06-10
RU2006106231A (en) 2006-06-27
PT1651644E (en) 2007-01-31
CY1105962T1 (en) 2011-04-06
CA2533673A1 (en) 2005-02-10
ES2276319T3 (en) 2007-06-16
MA27932A1 (en) 2006-06-01
AU2004261370A1 (en) 2005-02-10
DE502004002117D1 (en) 2007-01-04
AR045113A1 (en) 2005-10-19
NZ544975A (en) 2010-02-26
PA8607201A1 (en) 2005-03-03
MY141197A (en) 2010-03-31
CN100413862C (en) 2008-08-27
ZA200510378B (en) 2006-11-29
ECSP066326A (en) 2006-07-28
IL173289A0 (en) 2006-06-11
WO2005012295A1 (en) 2005-02-10
DK1651644T3 (en) 2007-03-26
UY28443A1 (en) 2005-02-28
RU2350613C2 (en) 2009-03-27
JO2449B1 (en) 2008-10-09
NO20060908L (en) 2006-02-24
PE20050326A1 (en) 2005-06-16
SA04250332B1 (en) 2008-02-25
CR8202A (en) 2008-10-15
PL1651644T3 (en) 2007-03-30
DE10334309A1 (en) 2005-03-03
ATE346065T1 (en) 2006-12-15
JP2007500145A (en) 2007-01-11
AU2004261370B2 (en) 2009-07-16
HK1091825A1 (en) 2007-01-26

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