[go: up one dir, main page]

FR04C0021I2 - Procede pour eliminer les sels biliaires chez un patient et compositions alkylees a cet effet - Google Patents

Procede pour eliminer les sels biliaires chez un patient et compositions alkylees a cet effet

Info

Publication number
FR04C0021I2
FR04C0021I2 FR04C0021C FR04C0021C FR04C0021I2 FR 04C0021 I2 FR04C0021 I2 FR 04C0021I2 FR 04C0021 C FR04C0021 C FR 04C0021C FR 04C0021 C FR04C0021 C FR 04C0021C FR 04C0021 I2 FR04C0021 I2 FR 04C0021I2
Authority
FR
France
Prior art keywords
patient
bile salts
alkylated
eliminating
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR04C0021C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geltex Pharmaceuticals Inc
Original Assignee
Geltex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22980525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR04C0021(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geltex Pharmaceuticals Inc filed Critical Geltex Pharmaceuticals Inc
Publication of FR04C0021I1 publication Critical patent/FR04C0021I1/fr
Application granted granted Critical
Publication of FR04C0021I2 publication Critical patent/FR04C0021I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/60—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/02—Alkylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/44—Preparation of metal salts or ammonium salts
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
    • C08L39/02—Homopolymers or copolymers of vinylamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR04C0021C 1994-06-10 2004-09-08 Procede pour eliminer les sels biliaires chez un patient et compositions alkylees a cet effet Active FR04C0021I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25843194A 1994-06-10 1994-06-10
PCT/US1995/007181 WO1995034585A1 (en) 1994-06-10 1995-06-05 Process for removing bile salts from a patient and alkylated compositions therefor

Publications (2)

Publication Number Publication Date
FR04C0021I1 FR04C0021I1 (de) 2007-10-26
FR04C0021I2 true FR04C0021I2 (fr) 2008-05-16

Family

ID=22980525

Family Applications (1)

Application Number Title Priority Date Filing Date
FR04C0021C Active FR04C0021I2 (fr) 1994-06-10 2004-09-08 Procede pour eliminer les sels biliaires chez un patient et compositions alkylees a cet effet

Country Status (21)

Country Link
US (12) US5693675A (de)
EP (2) EP0909768A3 (de)
JP (1) JP3931217B2 (de)
KR (1) KR100271693B1 (de)
CN (1) CN1150217C (de)
AT (1) ATE184027T1 (de)
AU (1) AU698752C (de)
CA (1) CA2191478C (de)
DE (3) DE122004000034I1 (de)
DK (1) DK0764174T3 (de)
ES (1) ES2135743T3 (de)
FR (1) FR04C0021I2 (de)
GR (1) GR3031702T3 (de)
IL (2) IL114073A (de)
LU (1) LU91100I2 (de)
MX (1) MX9606171A (de)
NL (1) NL300159I2 (de)
NZ (1) NZ288076A (de)
RU (1) RU2160742C2 (de)
TW (1) TW474813B (de)
WO (1) WO1995034585A1 (de)

Families Citing this family (131)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
TW474813B (en) * 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5925379A (en) * 1997-03-27 1999-07-20 Geltex Pharmaceuticals, Inc. Interpenetrating polymer networks for sequestration of bile acids
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6566407B2 (en) 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6299868B1 (en) 1999-07-14 2001-10-09 Geltex Pharmaceuticals, Inc. Fat-binding polymers
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
US7048917B1 (en) 1998-01-09 2006-05-23 Genzyme Corporation Fat-binding polymers
US6264937B1 (en) 1998-01-09 2001-07-24 Geltex Pharmaceuticals, Inc. Fat-binding polymers
US6294163B1 (en) 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4749649B2 (ja) * 1998-10-12 2011-08-17 中外製薬株式会社 リン酸結合性ポリマー
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
DE19850817A1 (de) * 1998-11-04 2000-05-11 Basf Ag Modifizierte kationische Polymere, Verfahren zu ihrer Herstellung und ihre Verwendung bei der Papierherstellung
US6271264B1 (en) 1998-12-01 2001-08-07 Geltex Pharmaceuticals, Inc. Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
WO2000063259A1 (en) 1999-04-16 2000-10-26 Abbott Laboratories Process for producing cross-linked polyallylamine hydrochloride
US6190649B1 (en) * 1999-04-23 2001-02-20 Geltex Pharmaceuticals, Inc. Polyether-based bile acid sequestrants
CA2379308A1 (en) * 1999-07-14 2001-01-25 Geltex Pharmaceuticals, Inc. Fat-binding polymers, optionally combined with lipase inhibitors
US6180754B1 (en) 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
EP1307264B1 (de) * 2000-07-28 2004-10-20 F. Hoffmann-La Roche Ag Neue pharmazeutische zusammensetzung
US8263112B2 (en) * 2000-11-20 2012-09-11 Sorbent Therapeutics, Inc. In vivo use of water absorbent polymers
AU2002232955A1 (en) 2000-11-20 2002-05-27 Dow Global Technologies Inc. In vivo use of water absorbent polymers
WO2002043744A1 (fr) 2000-11-28 2002-06-06 Mitsubishi Pharma Corporation Accelerateur d'excretion pour compose chlore accumule
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
US6710162B2 (en) 2001-02-16 2004-03-23 Genzyme Corporation Method of drying a material having a cohesive phase
NZ528831A (en) * 2001-04-18 2005-07-29 Genzyme Corp Method for lowering serum glucose
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
KR20040018359A (ko) * 2001-04-18 2004-03-03 젠자임 코포레이션 지방족 폴리아민으로 ｘ 증후군을 치료하는 방법
EP1923064B1 (de) 2001-04-18 2017-06-28 Genzyme Corporation Verwendung von Aminpolymeren zur Minderung des Serumglukosegehaltes
WO2002085380A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for treating gout and reducing serum uric acid
DE60212819T2 (de) * 2001-04-18 2006-11-23 Genzyme Corp., Cambridge Salzformarme polyallylamine
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US7049345B2 (en) * 2001-06-29 2006-05-23 Genzyme Corporation Fat-binding polymers
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
AT414237B (de) * 2002-09-03 2006-10-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von quaternären halogen-alkyl-ammoniumsalzen
AT411463B (de) 2002-09-03 2004-01-26 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von alkylierten n- bzw. amino-, ammonium- oder spirobicyclischen ammoniumgruppen haltigen, vernetzten polymeren
WO2004037274A1 (en) * 2002-10-22 2004-05-06 Genzyme Corporation Amine polymers for promoting bone formation
CA2526730A1 (en) 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Substituted pyrrole derivatives
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) * 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
WO2005092349A1 (ja) 2004-03-26 2005-10-06 Mitsubishi Pharma Corporation インスリン抵抗性改善剤
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
EP1732523B9 (de) * 2004-03-30 2010-06-02 Relypsa, Inc. Kaliumbindende polymere und ihre verwendungen
US8192758B2 (en) * 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7429394B2 (en) * 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) * 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
US7854924B2 (en) * 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US20090023606A1 (en) * 2004-08-12 2009-01-22 Versamatrix A/S Beaded and Cross-Linked Poly(Aminoalkylene)Matrix and Uses Thereof
US20080213568A1 (en) * 2004-08-27 2008-09-04 Versanatrux A/S Polyether Polymer Matrix
DE602005026819D1 (de) * 2004-08-27 2011-04-21 Novo Nordisk As Funktionelles harz mit hoher beladung
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP4547620B2 (ja) * 2004-12-02 2010-09-22 日東紡績株式会社 架橋アリルアミン類重合体の製造方法
MY144940A (en) * 2005-01-25 2011-11-30 Avantor Performance Mat Inc Chromatographic media
CA2601236A1 (en) * 2005-03-16 2006-09-21 Usv Limited An improved process for the preparation of crosslinked polyallylamine polymer
EP1951266A2 (de) 2005-09-02 2008-08-06 Genzyme Corporation Verfahren zur entfernung von phosphat und dafür verwendetes polymer
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
HUE026628T2 (en) 2005-09-15 2016-06-28 Genzyme Corp Pouches for amine polymers
DE112006002618T5 (de) 2005-09-30 2008-08-28 Ilypsa Inc., Santa Clara Verfahren und Zusammensetzungen zum selektiven Entfernen von Kaliumionen aus dem Gastrointestinaltrakt eines Säugers
US8586097B2 (en) * 2005-09-30 2013-11-19 Relypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
BRPI0618379A2 (pt) 2005-11-08 2011-08-30 Ranbaxy Lab Ltd processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
EP2016114A2 (de) * 2006-05-05 2009-01-21 Genzyme Corporation Aminkondensationspolymere als phosphatkomplexbildner
JP5147695B2 (ja) 2006-06-16 2013-02-20 田辺三菱製薬株式会社 糸球体疾患の予防及び／または治療剤
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
WO2008007376A2 (en) * 2006-07-13 2008-01-17 Association For Public Health Services Inoculation loop assembly
CA2658338A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
JP2010513271A (ja) 2006-12-14 2010-04-30 ゲンズイメ コーポレーション アミド−アミンポリマー組成物
WO2008079280A1 (en) 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8569464B2 (en) 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
EP2114376A1 (de) * 2007-02-23 2009-11-11 Genzyme Corporation Amin-polymerzusammensetzungen
US20100196305A1 (en) * 2007-03-08 2010-08-05 Dhal Pradeep K Sulfone polymer compositions
EP2152277A1 (de) * 2007-04-27 2010-02-17 Genzyme Corporation Amido-amin-dendrimer-zusammensetzungen
EP2016947A1 (de) * 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
PA8807201A1 (es) * 2007-12-14 2009-07-23 Genzyme Corp Composiciones farmaceuticas
EP2217215A1 (de) * 2007-12-14 2010-08-18 Genzyme Corporation Beschichtete pharmazeutische zusammensetzungen
WO2009151514A1 (en) 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
HUE061320T2 (hu) * 2008-08-22 2023-06-28 Vifor Int Ltd Térhálósított kationcserélõ polimerek, készítmények és ezek alkalmazása hiperkalémia kezelésében
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
WO2010022381A1 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
KR20110059750A (ko) * 2008-09-02 2011-06-03 유에스브이 리미티드 가교 폴리머
WO2010062734A1 (en) * 2008-11-03 2010-06-03 University Of Maryland, Baltimore Blood coagulation inducing polymer hydrogel
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
DK2370561T3 (da) 2008-12-16 2019-10-21 Emd Millipore Corp Omrøringstankreaktor og fremgangsmåde
US8673272B2 (en) * 2009-07-27 2014-03-18 Isp Investments Inc. Ultraviolet-absorbing compounds
GB0915449D0 (en) * 2009-09-04 2009-10-07 Univ Robert Gordon Composition
MX348821B (es) * 2010-02-24 2017-06-30 Relypsa Inc Polímeros de amina para usarse como secuestrantes del ácido biliar.
ES2549513T3 (es) 2010-02-24 2015-10-28 Relypsa, Inc. Polivinilamina, polialilamina y polietilenimina reticuladas para uso como secuestradores de ácidos biliares
EP3597671B1 (de) * 2010-05-17 2022-09-21 EMD Millipore Corporation Stimulusreaktive polymere zur aufreinigung von biomolekülen
TR201005327A2 (tr) 2010-06-30 2012-01-23 Bi̇lgi̇ç Mahmut Sinerjik farmasötik formülasyonlar.
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
AU2011326871B2 (en) 2010-11-04 2015-02-12 Albireo Ab IBAT inhibitors for the treatment of liver diseases
WO2012064267A1 (en) 2010-11-08 2012-05-18 Albireo Ab A pharmaceutical combination comprising an ibat inhibitor and a bile acid binder
JP6217938B2 (ja) 2011-10-28 2017-10-25 ルメナ ファーマシューティカルズ エルエルシー 小児の胆汁うっ滞性肝疾患の処置のための胆汁酸再循環阻害剤
CA2852957C (en) 2011-10-28 2020-08-04 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease
US20130123433A1 (en) 2011-11-14 2013-05-16 Formosa Laboratories, Inc. Method for preparing poly(allylamine) hydrochloride and derivatives therefrom
EP4684832A2 (de) 2012-10-08 2026-01-28 Vifor (International) Ltd. Kaliumbindende mittel zur behandlung von hyperkaliämie
ES2471340B1 (es) 2012-12-21 2015-08-17 Laboratorios Rubió, S.A. Composición farmacéutica oral para fármacos de elevada posología
JP6426694B2 (ja) * 2013-03-15 2018-11-21 グローバル ブラッド セラピューティクス インコーポレイテッド ヘモグロビンの修飾のための化合物及びその使用
CN103446179B (zh) * 2013-05-14 2017-03-15 厦门绿洲安源投资管理有限公司 作为磷酸盐、脂肪酸和胆汁酸绑定螯合剂的双亲聚富勒烯树状交联聚阳离子凝胶的应用
DK3003327T3 (en) 2013-06-05 2017-10-23 Tricida Inc PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
US9475891B2 (en) 2013-09-19 2016-10-25 Navinta, Llc Process for the preparation of colesevelam hydrochloride
WO2015075065A1 (en) 2013-11-20 2015-05-28 Sanovel Ilac Sanayi Ve Ticaret A.S. Tablet formulation of colesevelam
ITMI20132132A1 (it) 2013-12-19 2015-06-20 Chemi Spa Processo per la preparazione di colesevelam
AU2015274377B2 (en) 2014-06-13 2020-07-23 United Therapeutics Corporation Treprostinil formulations
MA48486B1 (fr) * 2014-12-10 2021-03-31 Tricida Inc Polymères liant les protons pour administration orale
EP3261624A1 (de) 2015-02-23 2018-01-03 Amneal Pharmaceuticals Company GmbH Verfahren zum granulieren von sevelamerkarbonat
EP3365381B1 (de) * 2015-10-21 2020-04-22 Saudi Arabian Oil Company Kationische polymere und poröse materialien
MX2018013476A (es) 2016-05-06 2019-03-28 Tricida Inc Composiciones para tratar trastornos acido-base.
CN106008813B (zh) * 2016-06-15 2017-11-14 新发药业有限公司 溶液聚合制备盐酸考来维仑的方法
WO2018111911A1 (en) 2016-12-14 2018-06-21 Ecolab USA, Inc. Quaternary cationic polymers
CN107232191B (zh) * 2017-06-22 2021-05-18 华中师范大学 一种全氟丁基改性聚乙烯亚胺大分子含氟表面活性剂及其制备与在农药缓释中的应用
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
WO2019241056A1 (en) 2018-06-12 2019-12-19 Ecolab Usa Inc. Quaternary cationic surfactants and polymers for use as release and coating modifying agents in creping and tissue papers
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580490A (fr) * 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3383281A (en) * 1961-09-22 1968-05-14 Merck & Co Inc Method for binding bile acids in vivo
US3308020A (en) * 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3288770A (en) * 1962-12-14 1966-11-29 Peninsular Chem Res Inc Water soluble quaternary ammonium polymers
BE756035A (fr) * 1969-09-12 1971-03-11 Inveresk Res Int Polymeres pontes
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
NL7017227A (de) * 1969-12-27 1971-06-29
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
AR206390A1 (es) 1973-02-05 1976-07-23 Rohm & Haas Una matriz de resina polimerica reticulada y procedimiento para su preparacion
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol
US4217429A (en) * 1973-06-11 1980-08-12 Merck & Co., Inc. Poly-[(methylimino)trimethylene]
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
CS187563B1 (en) * 1974-02-08 1979-02-28 Petr Strop Method of preparation of the hydrophilic homogeneous or macroporous annexes
CS173201B1 (de) * 1974-02-13 1977-02-28
US4016209A (en) * 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4101478A (en) * 1976-04-12 1978-07-18 Kostjuchenko Vladimir Mitrofan Synthetic rubber mix
US4071478A (en) * 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
FI67483C (fi) * 1977-02-17 1985-04-10 Merck & Co Inc Foerfarande foer framstaellning av ett icke adhesivt friflytande farmakologiskt godtagbart gallsyrakomplexbildande adsorbatpreparat
US4298715A (en) * 1978-03-01 1981-11-03 Monsanto Company Polyamine/epihalohydrin reaction products
JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent
IT1106718B (it) * 1978-12-21 1985-11-18 Alfa Farmaceutici Spa Composizioni a base di resine anioniche salificate farmacologicamente attive
US4557930A (en) * 1982-01-18 1985-12-10 Mitsubishi Petrochemical Co., Ltd. Anticholesteremic anion exchange resins
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
EP0142962A3 (de) * 1983-11-14 1986-01-15 Nitto Boseki Co., Ltd. Verfahren zur Herstellung von Polyallyaminderivaten
JPS60106803A (ja) * 1983-11-14 1985-06-12 Nitto Boseki Co Ltd アリル尿素重合体の製造方法
CA1220897A (en) * 1984-01-11 1987-04-21 Kiyoshi Shimizu Process for producing polymers of monoallylamine
EP0162388B1 (de) * 1984-05-11 1989-09-13 Bristol-Myers Company Galle-Komplexbildner-Harz und seine Verwendung
US4759923A (en) * 1987-06-25 1988-07-26 Hercules Incorporated Process for lowering serum cholesterol using poly(diallylmethylamine) derivatives
US5300566A (en) * 1988-04-15 1994-04-05 Air Products And Chemicals, Inc. Method for preparing poly(vinyl alcohol)-co-poly(vinylamine) via a two-phase process
DE3901527A1 (de) 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
US5236701A (en) * 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
GB8928278D0 (en) * 1989-12-14 1990-02-21 Smith Kline French Lab Compounds
GB9011332D0 (en) * 1990-05-21 1990-07-11 Smith Kline French Lab Compounds
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
US5055197A (en) * 1991-04-05 1991-10-08 Rohm And Haas Company Process for removing residual monomers and oligemers from amine-containing polymers
US5142019A (en) * 1991-10-03 1992-08-25 Ppg Industries, Inc. Oligomers formed from reaction of acrylamidoglycolate alkyl ethers with β-hydroxyalkylamines
DK0580078T3 (da) * 1992-07-22 1998-05-25 Hoechst Ag Polyvinylamin-derivater med hydrofyle centrer,fremgangsmåde til deres fremstilling samt anvendelse af forbindelserne som lægemidler, bærere af aktive stoffer og næringsmiddelhjælpestof.
EP0580079B1 (de) * 1992-07-22 1996-12-11 Hoechst Aktiengesellschaft Vernetzte, stickstoffhaltige Vinylcopolymere, Verfahren zu ihrer Herstellung sowie die Verwendung dieser Verbindungen
JP3412842B2 (ja) * 1992-07-28 2003-06-03 ミヨシ油脂株式会社 金属捕集剤及びその製造方法
SK31395A3 (en) * 1992-08-20 1995-08-09 Du Pont Crosslinked polymeric ammonium salts
US5451397A (en) * 1992-12-21 1995-09-19 Rohm And Haas Company Bile acid sequestrant
US5624963A (en) 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
JPH09500368A (ja) * 1993-06-02 1997-01-14 ジェルテックス ファーマシューティカルズ，インコーポレイテッド 胆汁酸塩を除去するための組成物および方法
US5703188A (en) 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) * 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient

Also Published As

Publication number Publication date
CN1150217C (zh) 2004-05-19
CA2191478C (en) 2007-10-16
DK0764174T3 (da) 2000-03-27
DE69511861T2 (de) 2000-02-10
IL142419A0 (en) 2002-03-10
AU698752B2 (en) 1998-11-05
US5917007A (en) 1999-06-29
US7101960B2 (en) 2006-09-05
GR3031702T3 (en) 2000-02-29
LU91100I9 (de) 2019-01-29
EP0764174B1 (de) 1999-09-01
JP3931217B2 (ja) 2007-06-13
KR100271693B1 (ko) 2000-11-15
IL114073A (en) 2003-06-24
US5693675A (en) 1997-12-02
US6784254B2 (en) 2004-08-31
RU2160742C2 (ru) 2000-12-20
TW474813B (en) 2002-02-01
ES2135743T3 (es) 1999-11-01
US7399821B2 (en) 2008-07-15
US20050131161A1 (en) 2005-06-16
US20020095002A1 (en) 2002-07-18
US5981693A (en) 1999-11-09
NZ288076A (en) 1998-08-26
US5679717A (en) 1997-10-21
MX9606171A (es) 1998-07-31
LU91100I2 (fr) 2004-11-08
CN1150435A (zh) 1997-05-21
EP0909768A3 (de) 2001-01-17
IL114073A0 (en) 1995-10-31
US20070155950A1 (en) 2007-07-05
DE69511861D1 (de) 1999-10-07
NL300159I1 (nl) 2004-11-01
US20090155201A1 (en) 2009-06-18
AU698752C (en) 2002-08-08
EP0909768A2 (de) 1999-04-21
DE122004000034I1 (de) 2005-02-24
US6225355B1 (en) 2001-05-01
US6066678A (en) 2000-05-23
US20040014899A1 (en) 2004-01-22
JPH10501842A (ja) 1998-02-17
ATE184027T1 (de) 1999-09-15
FR04C0021I1 (de) 2007-10-26
US6433026B2 (en) 2002-08-13
NL300159I2 (nl) 2004-12-01
DE122004000034I2 (de) 2006-04-27
AU2699095A (en) 1996-01-05
CA2191478A1 (en) 1995-12-21
US20010044519A1 (en) 2001-11-22
WO1995034585A1 (en) 1995-12-21
EP0764174A1 (de) 1997-03-26

Similar Documents

Publication Publication Date Title
FR04C0021I2 (fr) Procede pour eliminer les sels biliaires chez un patient et compositions alkylees a cet effet
EP0944552A4 (de) Methode zur entfernung von toxischen substanzen aus wasser
GB9521826D0 (en) Method and composition for clarifying waste water
FR2726754B1 (fr) Dispositif et procede pour l'examen des fonctions visuelles
ZA959552B (en) Method for use in casting technology
EP0706399A4 (de) Präparate und verfahren zur entfernung von gallensalzen
EE9700114A (et) Meetod ja seade heitvee töötlemiseks
FR2723835B1 (fr) Procede pour creer des affichages de mode m anatomique
FR2722123B1 (fr) Procede et dispositif pour le nettoyage d'endoscopes
EP0758234A4 (de) Verfahren und zusammensetzung zur behandlung von nierenerkrankungen und nierenversagen
EP0408082A3 (en) Water treatment agent and water treatment method for boiler
GB2305371B (en) Wear strip assembly for use in a waste water treatment facility
HUT75844A (en) Parts for supporting drinking water and method for treatment thereof
FI945392A7 (fi) Lamellirakenteinen laite ja menetelmä veden selkeyttämiseksi
GB2309019B (en) Method for transferring waste
FR2757401B1 (fr) Methode pour declencher l'ovulation chez un mammifere
IL110020A (en) Apparatus and method for purifying waste water
FI964426A7 (fi) Menetelmä orgaanista ainesta ja liuenneita suoloja sisältävän nesteen demineralisoimiseksi
HUP9601049A3 (en) Waste water treatment method
GB2285534B (en) Method for treating radioactive waste solution
ZA912113B (en) Method and composition for water treatment
FI921815A7 (fi) Menetelmä jätepaperin käsittelemiseksi hydroksisulfonaattisuolojen läs näollessa
GB9501400D0 (en) Method for treating water
FR2770094B1 (fr) Procede et dispositif pour creer des feuilles et des fleurs artificielles
EP1146549A4 (de) Verfahren und vorrichtung für die ionenimplantation