[go: up one dir, main page]

MX2018013476A - Composiciones para tratar trastornos acido-base. - Google Patents

Composiciones para tratar trastornos acido-base.

Info

Publication number
MX2018013476A
MX2018013476A MX2018013476A MX2018013476A MX2018013476A MX 2018013476 A MX2018013476 A MX 2018013476A MX 2018013476 A MX2018013476 A MX 2018013476A MX 2018013476 A MX2018013476 A MX 2018013476A MX 2018013476 A MX2018013476 A MX 2018013476A
Authority
MX
Mexico
Prior art keywords
compositions
treating acid
animal
human
methods
Prior art date
Application number
MX2018013476A
Other languages
English (en)
Inventor
Klaerner Gerrit
J Kade Matthew
H Kierstead Paul
M Buysse Jerry
H Nguyen Son
F Connor Eric
J Cope Michael
N Biyani Kalpesh
K Gbur Randi
M Tabakman Scott
Original Assignee
Tricida Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tricida Inc filed Critical Tricida Inc
Publication of MX2018013476A publication Critical patent/MX2018013476A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/02—Alkylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C08F226/04—Diallylamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

La presente invención se refiere a composiciones farmacéuticas para, y a métodos de tratamiento de, un animal, incluido un ser humano, y a métodos para preparar tales composiciones. Las composiciones farmacéuticas contienen composiciones no absorbibles y pueden usarse, por ejemplo, para tratar enfermedades u otras afecciones metabólicas en las que la eliminación de protones, la base conjugada de un ácido fuerte y/o un ácido fuerte, del tracto gastrointestinal, proporcionaría beneficios fisiológicos tales como normalizar las concentraciones en el suero del bicarbonato y el pH de la sangre en un animal, incluido un ser humano.
MX2018013476A 2016-05-06 2017-05-05 Composiciones para tratar trastornos acido-base. MX2018013476A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662333059P 2016-05-06 2016-05-06
US201662350686P 2016-06-15 2016-06-15
US201662408885P 2016-10-17 2016-10-17
US201662414966P 2016-10-31 2016-10-31
PCT/US2017/031378 WO2017193050A1 (en) 2016-05-06 2017-05-05 Compositions for treating acid-base disorders

Publications (1)

Publication Number Publication Date
MX2018013476A true MX2018013476A (es) 2019-03-28

Family

ID=59315687

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018013476A MX2018013476A (es) 2016-05-06 2017-05-05 Composiciones para tratar trastornos acido-base.

Country Status (15)

Country Link
US (6) US11406661B2 (es)
EP (3) EP3831395A1 (es)
JP (3) JP7071284B2 (es)
KR (1) KR102655774B1 (es)
CN (2) CN116211887A (es)
AU (3) AU2017261337A1 (es)
BR (1) BR112018072714A2 (es)
CA (1) CA3023264A1 (es)
IL (2) IL262660B2 (es)
MA (3) MA54925A (es)
MX (1) MX2018013476A (es)
MY (1) MY197091A (es)
RU (1) RU2018142943A (es)
SG (1) SG11201809605PA (es)
WO (3) WO2017193024A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3003327T3 (en) 2013-06-05 2017-10-23 Tricida Inc PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
MA48486B1 (fr) 2014-12-10 2021-03-31 Tricida Inc Polymères liant les protons pour administration orale
MX2018013476A (es) 2016-05-06 2019-03-28 Tricida Inc Composiciones para tratar trastornos acido-base.
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
JP7018451B2 (ja) * 2017-10-16 2022-02-10 富士フイルム株式会社 高リン血症治療剤および粒子
IL274223B2 (en) * 2017-11-03 2025-11-01 Tricida Inc A method for analyzing the effect of high levels of sodium bicarbonate in the serum of patients with metabolic acidosis and various uses of its results
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
EP3740201A4 (en) * 2018-06-04 2021-03-17 Tricida Inc. METHOD FOR TREATMENT OF ACID-BASE DISORDER
WO2019236639A1 (en) * 2018-06-04 2019-12-12 Tricida, Inc. Method of treating acid-base disorders
BR112023017628A2 (pt) 2021-03-01 2023-12-05 Tricida Inc Composições farmacêuticas de polímero de poli(alilamina) reticulado
PT4053179T (pt) 2021-03-01 2025-11-19 Renosis Inc Composições farmacêuticas de polímeros de poli(alilamina) reticulados
WO2023109826A1 (zh) * 2021-12-14 2023-06-22 上海石趣医药科技有限公司 碳酸银在制备药物中的用途
WO2023109825A1 (zh) * 2021-12-14 2023-06-22 上海石趣医药科技有限公司 氧化银和/或其水合物在制备药物中的用途

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444221B1 (en) 1992-06-30 2002-09-03 Howard K. Shapiro Methods of treating chronic inflammatory diseases using carbonyl trapping agents
US20050090553A1 (en) 1992-06-30 2005-04-28 Shapiro Howard K. Compositions and method for treatment of chronic inflammatory diseases
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5648355A (en) 1994-02-09 1997-07-15 Kos Pharmaceutical, Inc. Method of treatment of endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
EP0786993B1 (en) 1994-10-17 2002-06-05 Peter W. Stacpoole Compositions comprising carbonate/bicarbonate buffered dichloroacetic acid and their use in the treatment of metabolic and cardiovascular disorders
US20020006899A1 (en) 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
US5753706A (en) 1996-12-16 1998-05-19 Hsu; Chen Hsing Methods for treating renal failure
AUPO758297A0 (en) 1997-06-27 1997-07-24 Rowe, James Baber Control of acidic gut syndrome
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
AU2682499A (en) 1998-02-17 1999-08-30 Dimitri R. Kioussis Anion binding polymers and the use thereof
US6485703B1 (en) 1998-07-31 2002-11-26 The Texas A&M University System Compositions and methods for analyte detection
US6271264B1 (en) 1998-12-01 2001-08-07 Geltex Pharmaceuticals, Inc. Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
GB9927088D0 (en) 1999-11-17 2000-01-12 Secr Defence Use of poly(diallylamine) polymers
AU2001241076A1 (en) 2000-03-09 2001-09-17 Hisamitsu Pharmaceutical Co. Inc. Crosslinked anion-exchange resin or salt thereof
AU2001241077A1 (en) 2000-03-09 2001-09-17 Hisamitsu Pharmaceutical Co. Inc. Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
EP1283046A1 (en) 2000-03-13 2003-02-12 Hisamitsu Pharmaceutical Co., Inc. Preventives and/or remedies for hyperphosphatemia
JP2002028737A (ja) 2000-07-07 2002-01-29 Fujitsu Ltd プレス打ち抜き加工方法及びプレス打ち抜き加工装置
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
CA2444347A1 (en) 2001-04-18 2002-10-31 Genzyme Corporation Method for treating gout and binding uric acid
DE60212819T2 (de) 2001-04-18 2006-11-23 Genzyme Corp., Cambridge Salzformarme polyallylamine
AU2003214112A1 (en) 2002-03-11 2003-09-22 Novartis Ag Salts of nateglinide
US20070135335A1 (en) 2003-02-10 2007-06-14 Autogen Research Pty Ltd. Therapeutic molecules
TWI335218B (en) 2003-02-19 2011-01-01 Panion & Bf Biotech Inc Ferric organic compounds, uses thereof and methods of making same
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
EP1699442A2 (en) 2003-12-31 2006-09-13 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
WO2005072773A1 (ja) 2004-01-29 2005-08-11 Keio University 赤血球機能修飾物質
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
EP1732523B9 (en) 2004-03-30 2010-06-02 Relypsa, Inc. Potassium binding polymers and uses thereof
US8192758B2 (en) 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7556799B2 (en) 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US7429394B2 (en) 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
US8282960B2 (en) 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
US8399025B2 (en) 2004-06-04 2013-03-19 Board Of Regents, The University Of Texas System Polyamine modified particles
NZ552706A (en) 2004-07-19 2011-01-28 Nutricia Nv Use of aspartate for regulating glucose levels in blood
DE102004035808A1 (de) 2004-07-21 2006-03-16 Kasch, Helmut, Dr. Ammoniumsalze und Ammoniumsalz-Mineralsalzchlatrate als Transport- und Wirkform für pharmazeutische-medizinische und als Phasentransfermittel für chemische Anwendungen
US8569277B2 (en) 2004-08-11 2013-10-29 Palo Alto Investors Methods of treating a subject for a condition
US20070293429A1 (en) 2004-10-08 2007-12-20 Therapei Pharmaceuticals, Inc. Vasoactive Intestinal Polypeptide Compositions
US20080214440A1 (en) 2004-10-08 2008-09-04 Forbes Medi-Tech (Research), Inc. Vasoactive intestinal polypeptide compositions
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
ITME20040015A1 (it) 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
WO2007004236A2 (en) 2005-07-04 2007-01-11 Ramu Krishnan Improved drug or pharmaceutical compounds and a preparation thereof
ES2539635T3 (es) 2005-08-18 2015-07-02 Panion & Bf Biotech Inc. Citrato férrico de grado farmacéutico para uso médico
EP1951266A2 (en) 2005-09-02 2008-08-06 Genzyme Corporation Method for removing phosphate and polymer used therefore
US8586097B2 (en) 2005-09-30 2013-11-19 Relypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
WO2007038801A2 (en) 2005-09-30 2007-04-05 Ilypsa, Inc. Monovalent cation-binding compositions comprising core-shell particles having crosslinked poly-vinylic shells, and methods of use thereof
DE112006002618T5 (de) 2005-09-30 2008-08-28 Ilypsa Inc., Santa Clara Verfahren und Zusammensetzungen zum selektiven Entfernen von Kaliumionen aus dem Gastrointestinaltrakt eines Säugers
US20090162314A1 (en) 2005-11-08 2009-06-25 Huval Chad C Magnesium-Containing Polymers for the Treatment of Hyperphosphatemia
CN102600202A (zh) 2005-11-08 2012-07-25 味之素株式会社 麻醉苏醒促进剂
ITMI20052461A1 (it) 2005-12-22 2007-06-23 Univ Degli Studi Milano Sistemi microparticellari per la somministrazione orale di sostanze biologicamente attive
RU2008136081A (ru) 2006-02-14 2010-03-20 Тева Фармасьютикл Индастриес Лтд. (Il) Фармацевтические составы с алифатическими аминными полимерами и способы их производства
EP2016114A2 (en) 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
EP2043627A2 (en) 2006-07-05 2009-04-08 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
CA2658338A1 (en) 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
AU2007281433A1 (en) 2006-08-04 2008-02-07 Nastech Pharmaceutical Company Inc. Compositions for intranasal delivery of human insulin and uses thereof
WO2008027551A2 (en) 2006-09-01 2008-03-06 Genzyme Corporation Dendrimer compositions
CA2661987C (en) 2006-09-01 2012-11-06 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2059247A1 (en) 2006-09-06 2009-05-20 Sucampo AG Method and composition for promoting gastrointestinal bicarbonate secretion
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
JP2010513271A (ja) 2006-12-14 2010-04-30 ゲンズイメ コーポレーション アミド−アミンポリマー組成物
EP2114376A1 (en) 2007-02-23 2009-11-11 Genzyme Corporation Amine polymer compositions
US20080207766A1 (en) 2007-02-27 2008-08-28 Agi Therapeutics Research Ltd. Methods and compositions for treating at least one upper gastrointestinal symptom
US20100196305A1 (en) 2007-03-08 2010-08-05 Dhal Pradeep K Sulfone polymer compositions
TWI445540B (zh) 2007-04-20 2014-07-21 Ajinomoto Kk 抗低體溫組成物
EP2152277A1 (en) 2007-04-27 2010-02-17 Genzyme Corporation Amido-amine dendrimer compositions
WO2009005838A2 (en) 2007-07-02 2009-01-08 Cognate3 Llc Process for the preparation of a non-corrosive base solution and methods of using same
EP2168992A1 (en) 2007-07-11 2010-03-31 Toray Industries, Inc. Crosslinked polyallylamine or acid addition salt thereof, and use thereof for medical purposes
EP2016947A1 (en) 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Novel one step process for preparing cross-linked poly(allylamine) polymers
WO2009023544A2 (en) 2007-08-10 2009-02-19 Ilypsa, Inc. Dosage unit anion-exchange polymer pharmaceutical compositions
US20090156647A1 (en) 2007-12-12 2009-06-18 Iovate T. & P. Inc. Method for maintaining physiological pH levels during intensive physical exercise
PA8807201A1 (es) 2007-12-14 2009-07-23 Genzyme Corp Composiciones farmaceuticas
EP2217215A1 (en) 2007-12-14 2010-08-18 Genzyme Corporation Coated pharmaceutical compositions
WO2009097127A1 (en) 2008-01-31 2009-08-06 Genzyme Corporation Pharmaceutical compositions
CA2732764C (en) 2008-03-11 2023-04-04 Livionex Inc. Methods and compositions for treating inflammation and inflammation-related pathologies
KR20100133468A (ko) 2008-04-08 2010-12-21 유에스브이 리미티드 아민 폴리머 염의 제조 방법
WO2009154747A1 (en) 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US20100008988A1 (en) 2008-07-14 2010-01-14 Glenmark Generics, Ltd. Tablet compositions of amine polymers
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
WO2010022381A1 (en) 2008-08-22 2010-02-25 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
MX342439B (es) 2008-09-25 2016-09-29 Vive Nano Inc * Metodos para producir nanoparticulas polimericas y formulaciones de ingredientes activos.
WO2010035273A2 (en) 2008-09-29 2010-04-01 Intec Pharma Ltd. Novel gastroretentive delivery system
US20100113479A1 (en) 2008-10-30 2010-05-06 Anusuya Choudhury Process for the preparation of tri-substituted pyridine and tri-substituted pyrimidine derivatives useful as gdir agonists
US20100166861A1 (en) 2008-12-29 2010-07-01 Kelly Noel Lynch Pharmaceutical formulations of sevalamer, or salts thereof, and copovidone
US20110081413A1 (en) * 2009-01-22 2011-04-07 Ashok Omray Pharmaceutical Compositions Comprising Phosphate-Binding Polymer
AU2010318637A1 (en) 2009-10-13 2012-05-31 The Regents Of The University Of Michigan Dendrimer compositions and methods of synthesis
ES2720869T3 (es) 2009-10-22 2019-07-25 Synthon Bv Composiciones farmacéuticas de sevelámero
JP5984675B2 (ja) 2009-12-07 2016-09-06 アイアンウッド ファーマシューティカルズ インコーポレイテッド 胃腸障害の療法
ES2549513T3 (es) 2010-02-24 2015-10-28 Relypsa, Inc. Polivinilamina, polialilamina y polietilenimina reticuladas para uso como secuestradores de ácidos biliares
GB2490853B (en) 2010-02-24 2018-08-08 Relypsa Inc Polyimidazoles for use as bile acid sequestrants
IT1406068B1 (it) * 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
KR101238210B1 (ko) 2011-06-30 2013-03-04 엘지전자 주식회사 이동 단말기
US20130137772A1 (en) 2011-11-29 2013-05-30 Raymond J. Bergeron Hydroxypolyamine salts
ES2796254T3 (es) 2012-06-21 2020-11-26 Keryx Biopharmaceuticals Inc Uso de citrato férrico en el tratamiento de pacientes con enfermedad renal crónica
EP4684832A2 (en) 2012-10-08 2026-01-28 Vifor (International) Ltd. Potassium-binding agents for treating hypertension and hyperkalemia
DK3003327T3 (en) 2013-06-05 2017-10-23 Tricida Inc PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION
EP3065734A4 (en) 2013-11-04 2017-05-17 Keryx Biopharmaceuticals, Inc. Ferric citrate for reducing cardiac failure in chronic kidney disease patients
MA48486B1 (fr) 2014-12-10 2021-03-31 Tricida Inc Polymères liant les protons pour administration orale
MX2018013476A (es) 2016-05-06 2019-03-28 Tricida Inc Composiciones para tratar trastornos acido-base.
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
IL274223B2 (en) 2017-11-03 2025-11-01 Tricida Inc A method for analyzing the effect of high levels of sodium bicarbonate in the serum of patients with metabolic acidosis and various uses of its results
WO2019236639A1 (en) 2018-06-04 2019-12-12 Tricida, Inc. Method of treating acid-base disorders
EP3740201A4 (en) 2018-06-04 2021-03-17 Tricida Inc. METHOD FOR TREATMENT OF ACID-BASE DISORDER
WO2019236124A1 (en) 2018-06-04 2019-12-12 Tricida, Inc. Method of treating acid-base disorders
US20200306209A1 (en) 2019-03-27 2020-10-01 Tricida, Inc. Method of treating acid-base disorders

Also Published As

Publication number Publication date
JP2022106914A (ja) 2022-07-20
MA44886A (fr) 2019-03-13
RU2018142943A (ru) 2020-06-08
EP3452028A1 (en) 2019-03-13
IL262660B2 (en) 2024-04-01
IL262660A (en) 2018-12-31
IL262660B1 (en) 2023-12-01
US20210205351A1 (en) 2021-07-08
MY197091A (en) 2023-05-24
US11406661B2 (en) 2022-08-09
AU2023202111B2 (en) 2025-05-15
JP2025157428A (ja) 2025-10-15
BR112018072714A2 (pt) 2019-02-19
MA54925A (fr) 2021-12-22
US11992501B2 (en) 2024-05-28
US20200054669A1 (en) 2020-02-20
CA3023264A1 (en) 2017-11-09
RU2018142943A3 (es) 2020-08-10
WO2017193050A1 (en) 2017-11-09
IL308673A (en) 2024-01-01
JP7071284B2 (ja) 2022-05-18
WO2017193064A1 (en) 2017-11-09
US20190134076A1 (en) 2019-05-09
US20250009785A1 (en) 2025-01-09
KR102655774B1 (ko) 2024-04-05
AU2025217383A1 (en) 2025-09-04
EP3831395A1 (en) 2021-06-09
CN109414453B (zh) 2023-02-17
CN116211887A (zh) 2023-06-06
EP3452028A4 (en) 2020-04-15
WO2017193024A9 (en) 2018-11-22
EP3452057A1 (en) 2019-03-13
AU2017261337A1 (en) 2018-11-15
SG11201809605PA (en) 2018-11-29
MA44875A (fr) 2019-03-13
JP2019514965A (ja) 2019-06-06
CN109414453A (zh) 2019-03-01
US20220062328A1 (en) 2022-03-03
AU2023202111A1 (en) 2023-05-04
KR20180133931A (ko) 2018-12-17
US20190209607A1 (en) 2019-07-11
WO2017193024A1 (en) 2017-11-09

Similar Documents

Publication Publication Date Title
MY197091A (en) Compositions for treating acid-base disorders
MX2021013880A (es) Polimeros enlazados al proton para administracion oral.
MX2021004558A (es) Polimeros de union a protones para administracion oral.
JOP20200231A1 (ar) ناهضات ppar (مستقبل ناشر بيروكسيزوم منشط)، ومركبات، ومكونات أدوية، وطرق استعمالها
BR112015009948A8 (pt) Antagonistas de ativina-actrii, usos dos mesmos para tratamento de doenças ósseas e outros distúrbios e método para monitorar a eficácia do tratamento ou prevenção de uma doença óssea e outros distúrbios
GT201600084A (es) (aza) piridopirazolopirimidinonas e indazolopirimidinonas y su uso
MY178445A (en) Novel antibody binding to tfpi and composition comprising the same
EA202091446A1 (ru) Способы лечения хронических воспалительных заболеваний
NZ754328A (en) Marker for acid sphingomyelinase disorders and uses thereof
MX357888B (es) Sales basicas de adicion de nitroxolina y usos de las mismas.
UA109359C2 (xx) Лікування захворювань і станів шкіри 7-(1h-імідазол-4-ілметил)-5,6,7,8-тетрагідрохіноліном
WO2013090965A3 (de) Zusammensetzung enthaltend antikörper gegen gluten und gerbstoffe
EA201600229A1 (ru) Бис(5-амино-1,4-диоксо-1,2,3,4-тетрагидрофталазин-2-ил)цинк, способ его получения, фармацевтическая композиция на его основе, лечебные средства на его основе, способ лечения кожных заболеваний и способ лечения гастрита
MX2015009483A (es) Pinzas para reparacion percutanea de tendon de aquiles por minima invasion.
Bazylev et al. Comparative analysis of the results of using the method of elimination of sternal infection and standard methodology of cardiosurgical operations
EA201991502A1 (ru) Композиции на основе аминокислот и способы лечения заболеваний печени
CY1114276T1 (el) Χρηση αιθυλεστερα εικοσαπενταενοϊκου οξεος για θεραπεια υπερτριγλυκεριδαιμιας
RU2010145617A (ru) Способ лечения больных с черепно-мозговой травмой на фоне гипертензионного синдрома в острый период