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FI963859L - Kolme ydintä käsittävät kationiset platinakompleksit, joilla on kasvaimenvastainen vaikutus, sekä niitä sisältävät farmaseuttiset koostumukset - Google Patents

Kolme ydintä käsittävät kationiset platinakompleksit, joilla on kasvaimenvastainen vaikutus, sekä niitä sisältävät farmaseuttiset koostumukset Download PDF

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Publication number
FI963859L
FI963859L FI963859A FI963859A FI963859L FI 963859 L FI963859 L FI 963859L FI 963859 A FI963859 A FI 963859A FI 963859 A FI963859 A FI 963859A FI 963859 L FI963859 L FI 963859L
Authority
FI
Finland
Prior art keywords
nuclei
pharmaceutical compositions
compositions containing
antitumor activity
platinum complexes
Prior art date
Application number
FI963859A
Other languages
English (en)
Swedish (sv)
Other versions
FI116058B (fi
FI963859A0 (fi
Inventor
Mariella Valsecchi
Marco Conti
Greco Luisa Del
Carlo Bugatti
Ernesto Menta
Ferdinando Giuliani
Carla Manzotti
Silvano Spinelli
Nicholas Farrell
Original Assignee
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia filed Critical Boehringer Mannheim Italia
Publication of FI963859L publication Critical patent/FI963859L/fi
Publication of FI963859A0 publication Critical patent/FI963859A0/fi
Application granted granted Critical
Publication of FI116058B publication Critical patent/FI116058B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI963859A 1994-03-31 1996-09-27 Kolme ydintä käsittävät kationiset platinakompleksit, joilla on kasvaimenvastainen vaikutus, sekä niitä sisältävät farmaseuttiset koostumukset FI116058B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI940610 1994-03-31
ITMI940610A IT1273391B (it) 1994-03-31 1994-03-31 Platino complessi cationici trinucleari ad attivita' antitumorale e composizioni farmaceutiche che li contengono
EP9501074 1995-03-22
PCT/EP1995/001074 WO1995026968A1 (en) 1994-03-31 1995-03-22 Trinuclear cationic platinum complexes having antitumour activity and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
FI963859L true FI963859L (fi) 1996-09-27
FI963859A0 FI963859A0 (fi) 1996-09-27
FI116058B FI116058B (fi) 2005-09-15

Family

ID=11368427

Family Applications (1)

Application Number Title Priority Date Filing Date
FI963859A FI116058B (fi) 1994-03-31 1996-09-27 Kolme ydintä käsittävät kationiset platinakompleksit, joilla on kasvaimenvastainen vaikutus, sekä niitä sisältävät farmaseuttiset koostumukset

Country Status (21)

Country Link
US (1) US5744497A (fi)
EP (1) EP0753000B1 (fi)
JP (1) JP2761297B2 (fi)
KR (1) KR100239787B1 (fi)
CN (1) CN1065537C (fi)
AT (1) ATE176478T1 (fi)
AU (1) AU682105B2 (fi)
CA (1) CA2186731C (fi)
CZ (1) CZ286404B6 (fi)
DE (1) DE69507694T2 (fi)
DK (1) DK0753000T3 (fi)
ES (1) ES2129847T3 (fi)
FI (1) FI116058B (fi)
GR (1) GR3030048T3 (fi)
HU (1) HU215129B (fi)
IT (1) IT1273391B (fi)
NO (1) NO308078B1 (fi)
NZ (1) NZ283143A (fi)
RU (1) RU2130941C1 (fi)
WO (1) WO1995026968A1 (fi)
ZA (1) ZA952636B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380897A (en) * 1993-05-25 1995-01-10 Hoeschele; James D. Tri(platinum) complexes
IT1271089B (it) * 1994-11-24 1997-05-26 Boehringer Mannheim Italia Platino complessi cationici trinucleari ad attivita' antitumorale
ZA976422B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polymethylene derivatives as ligands having antitumor activity.
ZA976421B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polyamine ligands as antitumor agents.
IT1292481B1 (it) * 1997-07-04 1999-02-08 Boehringer Mannheim Italia Platino complessi cationici tetra- e penta-nucleari ad attivita' antitumorale
KR100314720B1 (ko) * 1999-03-26 2001-11-26 박호군 포스파젠 삼합체에 도입된 백금 착물, 그의 제조방법 및 그를 유효성분으로 하는 항암제
EP1215199A1 (en) * 2000-12-08 2002-06-19 Sony International (Europe) GmbH Linker molecules for selective metallisation of nucleic acids and their uses
JP4007000B2 (ja) * 2001-12-25 2007-11-14 富士ゼロックス株式会社 導電性有機高分子
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
EP1859797A4 (en) * 2005-02-28 2011-04-13 Eisai R&D Man Co Ltd NEW SIMULTANEOUS USE OF A SULPHONAMIDE COMPOUND AND A MEDIUM AGAINST CANCER
CN102516315B (zh) * 2011-12-12 2014-12-10 中山大学 一种具有y型结构的三核铂配合物及其对人胃腺癌细胞的靶向性
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей
CN109988185B (zh) * 2019-05-09 2021-03-19 邵阳学院 具有抗肿瘤选择性的铂镝杂金属化合物及其制备方法
CN112745426B (zh) * 2019-10-31 2022-03-01 中国石油化工股份有限公司 用于制备烯烃-烯烃醇共聚物的方法
WO2021083358A1 (zh) 2019-10-31 2021-05-06 中国石油化工股份有限公司 用于制备烯烃-极性单体共聚物的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364072A (en) * 1978-03-17 1982-12-14 Zaidan Hojin Handotai Kenkyu Shinkokai Static induction type semiconductor device with multiple doped layers for potential modification
SU1570649A3 (ru) * 1984-09-12 1990-06-07 Чугаи Сейяку Кабусики Кайся (Фирма) Способ получени комплексных соединений платины
US5107007A (en) * 1989-09-01 1992-04-21 The University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
DE3630497A1 (de) * 1986-09-08 1988-03-10 Behringwerke Ag Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
CA1306693C (en) * 1986-10-07 1992-08-25 Sergio Tognella Pharmaceutical compositions having antineoplastic activity
US5049686A (en) * 1989-09-13 1991-09-17 Warner-Lambert Company Novel large-ring diamine platinum(II) and platinum(IV) chelates
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
US5380897A (en) * 1993-05-25 1995-01-10 Hoeschele; James D. Tri(platinum) complexes

Also Published As

Publication number Publication date
NZ283143A (en) 1997-09-22
ITMI940610A0 (it) 1994-03-31
JPH09506633A (ja) 1997-06-30
ATE176478T1 (de) 1999-02-15
ZA952636B (en) 1996-01-02
IT1273391B (it) 1997-07-08
AU682105B2 (en) 1997-09-18
FI116058B (fi) 2005-09-15
CZ284996A3 (en) 1997-04-16
EP0753000B1 (en) 1999-02-03
HUT76293A (en) 1997-07-28
CZ286404B6 (en) 2000-04-12
AU2110995A (en) 1995-10-23
KR970702287A (ko) 1997-05-13
HU215129B (hu) 1998-09-28
JP2761297B2 (ja) 1998-06-04
GR3030048T3 (en) 1999-07-30
KR100239787B1 (ko) 2000-02-01
CN1145624A (zh) 1997-03-19
NO963926L (no) 1996-09-19
HU9602663D0 (en) 1996-11-28
WO1995026968A1 (en) 1995-10-12
DE69507694D1 (de) 1999-03-18
CA2186731A1 (en) 1995-10-12
CA2186731C (en) 2005-06-07
ES2129847T3 (es) 1999-06-16
DK0753000T3 (da) 1999-09-20
ITMI940610A1 (it) 1995-10-01
US5744497A (en) 1998-04-28
NO963926D0 (no) 1996-09-19
FI963859A0 (fi) 1996-09-27
NO308078B1 (no) 2000-07-17
DE69507694T2 (de) 1999-07-22
CN1065537C (zh) 2001-05-09
RU2130941C1 (ru) 1999-05-27
EP0753000A1 (en) 1997-01-15

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Owner name: F.HOFFMANN-LA ROCHE AG

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