FI945957L - N-substituoidut 3-atsabisyklo/3.2.0/heptaanijohdannaiset neurolepteinä jne. - Google Patents

N-substituoidut 3-atsabisyklo/3.2.0/heptaanijohdannaiset neurolepteinä jne. Download PDF

Info

Publication number: FI945957L
Authority: FI; Finland
Prior art keywords: neuroleptics; azabicyclo; substituted; heptane derivatives; heptane
Prior art date: 1992-06-19

Application number

FI945957A

Other languages

English (en)

Swedish (sv)

Other versions

FI108726B (fi

FI945957A0 (fi

Inventor

Gerd Steiner

Liliane Unger

Berthold Behl

Hans-Juergen Teschendorf

Rainer Munschauer

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-19

Filing date

1994-12-19

Publication date

1994-12-19

1994-12-19 Application filed by Basf Ag filed Critical Basf Ag

1994-12-19 Publication of FI945957L publication Critical patent/FI945957L/fi

1994-12-19 Publication of FI945957A0 publication Critical patent/FI945957A0/fi

2002-03-15 Application granted granted Critical

2002-03-15 Publication of FI108726B publication Critical patent/FI108726B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI945957A 1992-06-19 1994-12-19 Menetelmä kaavan (I) mukaisten N-substituoitujen 3-atsabisyklo[3.2.0]heptaanijohdannaisten valmistamiseksi FI108726B (fi)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
DE4219974		1992-06-19
DE4219974		1992-06-19
DE4243287		1992-12-21
DE4243287A DE4243287A1 (de)	1992-06-19	1992-12-21	N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1993/001438 WO1994000458A1 (de)	1992-06-19	1993-06-08	N-substituierte 3-azabicyclo[3.2.0]heptanderivate als neuroleptika usw.
EP9301438		1993-06-08
CN93114691A CN1039996C (zh)	1992-06-19	1993-12-11	N－取代氮杂双环庚烷衍生物及其用途
CN93114691		1993-12-11

Publications (3)

Publication Number	Publication Date
FI945957L true FI945957L (fi)	1994-12-19
FI945957A0 FI945957A0 (fi)	1994-12-19
FI108726B FI108726B (fi)	2002-03-15

Family

ID=36940125

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI945957A FI108726B (fi)	1992-06-19	1994-12-19	Menetelmä kaavan (I) mukaisten N-substituoitujen 3-atsabisyklo[3.2.0]heptaanijohdannaisten valmistamiseksi

Country Status (24)

Country	Link
US (1)	US5475105A (fi)
EP (1)	EP0647231B1 (fi)
JP (1)	JP3171258B2 (fi)
CN (2)	CN1042133C (fi)
AT (1)	ATE157366T1 (fi)
AU (1)	AU671130B2 (fi)
BG (1)	BG62350B2 (fi)
CA (1)	CA2138289C (fi)
CZ (1)	CZ288787B6 (fi)
DE (2)	DE4243287A1 (fi)
DK (1)	DK0647231T3 (fi)
ES (1)	ES2107035T3 (fi)
FI (1)	FI108726B (fi)
GR (1)	GR3025095T3 (fi)
HU (1)	HU218911B (fi)
IL (1)	IL105989A (fi)
NO (1)	NO305176B1 (fi)
NZ (1)	NZ253121A (fi)
PH (1)	PH30466A (fi)
RU (1)	RU2135503C1 (fi)
SG (1)	SG44782A1 (fi)
TW (1)	TW408126B (fi)
WO (1)	WO1994000458A1 (fi)
ZA (1)	ZA934374B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4427648A1 (de) *	1994-08-04	1996-02-08	Basf Ag	N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
DE4338396A1 (de) *	1993-11-10	1995-05-11	Basf Ag	N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) *	1993-12-04	1995-06-08	Basf Ag	N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) *	1993-12-04	1995-06-08	Basf Ag	N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) *	1994-08-04	1996-02-08	Basf Ag	N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5929080A (en) *	1997-05-06	1999-07-27	American Cyanamid Company	Method of treating polycystic kidney disease
US6323209B1 (en)	1997-11-06	2001-11-27	American Cyanamid Company	Method of treating or inhibiting colonic polyps
US6458821B1 (en)	1998-08-12	2002-10-01	Abbott Laboratories	N-substituted azabicycloheptane derivatives, production and use thereof
DE19836406A1 (de) *	1998-08-12	2000-02-17	Basf Ag	N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836404A1 (de) *	1998-08-12	2000-02-17	Basf Ag	N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19848521A1 (de) *	1998-10-21	2000-04-27	Basf Ag	Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19960074A1 (de) *	1999-12-13	2001-06-21	Basf Ag	Neues Salz von Belaperidone und dessen Modifikationen
AU2001213156A1 (en) *	2000-08-16	2002-02-25	Elena Alexandrovna Izakson	Thiazine derivatives of general formula (1) having antibacterial and antiviral action
MX2007004358A (es) *	2004-10-14	2007-07-17	Abbott Gmbh & Co Kg	Compuestos de azabicicloheptilo adecuados para tratar trastornos que responden a la modulacion del receptor de dopamina d3.
EP1874801A4 (en) *	2005-03-07	2009-03-25	Univ North Carolina	MEANS OF INHIBITING RECA ACTIVITIES FOR THE CONTROL OF ANTIBIOTIC-SITES BACTERIAL PATHOGENESE
DK2083811T3 (en)	2006-11-22	2017-01-30	Clinical Res Ass Llc	PROCEDURES FOR TREATING DOWNS SYNDROME, FRAGILT X SYNDROME AND AUTISM
AU2008281399A1 (en) *	2007-07-27	2009-02-05	Actelion Pharmaceuticals Ltd	2-aza-bicyclo[3.3.0]octane derivatives
DK3186242T3 (da)	2014-08-29	2021-12-20	Tes Pharma S R L	Alfa-amino-beta-carboxymuconsyre-semialdehyd-decarboxylasehæmmere
CN112010851A (zh) *	2020-06-30	2020-12-01	浙江美诺华药物化学有限公司	一种莫西沙星盐酸盐的制备方法
WO2022194801A1 (en) *	2021-03-17	2022-09-22	F. Hoffmann-La Roche Ag	New thiazolopyrimidinone derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3155668A (en) *	1960-04-11	1964-11-03	Sterling Drug Inc	1-[3-, 2-, and 1-indolyl)-lower-alkyl]-tertiary amines and intermediates therefor
US3328390A (en) *	1962-02-27	1967-06-27	Tri Kem Corp	Certain azabicycloalkane compounds
US4443451A (en) *	1981-07-15	1984-04-17	Janssen Pharmaceutica N.V.	Bicyclic pyrimidin-5-one derivatives
SU1004389A1 (ru) *	1981-07-29	1983-03-15	Институт Органической Химии Ан Усср	Способ получени производных тиазоло/3,4-а/пиримидинов
DE3228303A1 (de) *	1982-07-29	1984-02-02	Robert Bosch Gmbh, 7000 Stuttgart	Elektrische motorregelung
US4540318A (en) *	1982-07-29	1985-09-10	Robert Bosch, Gmbh	Rotary electrical tool with speed control, especially drill
US4605655A (en) *	1984-03-06	1986-08-12	Bristol-Myers Company	Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4804663A (en) *	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

1992
- 1992-12-21 DE DE4243287A patent/DE4243287A1/de not_active Withdrawn
1993
- 1993-06-08 ES ES93912910T patent/ES2107035T3/es not_active Expired - Lifetime
- 1993-06-08 WO PCT/EP1993/001438 patent/WO1994000458A1/de not_active Ceased
- 1993-06-08 HU HU9403641A patent/HU218911B/hu not_active IP Right Cessation
- 1993-06-08 AT AT93912910T patent/ATE157366T1/de not_active IP Right Cessation
- 1993-06-08 JP JP51781793A patent/JP3171258B2/ja not_active Expired - Fee Related
- 1993-06-08 DK DK93912910.2T patent/DK0647231T3/da active
- 1993-06-08 SG SG1996007476A patent/SG44782A1/en unknown
- 1993-06-08 CZ CZ19943237A patent/CZ288787B6/cs not_active IP Right Cessation
- 1993-06-08 DE DE59307217T patent/DE59307217D1/de not_active Expired - Fee Related
- 1993-06-08 RU RU95105435/04A patent/RU2135503C1/ru not_active IP Right Cessation
- 1993-06-08 CA CA002138289A patent/CA2138289C/en not_active Expired - Fee Related
- 1993-06-08 EP EP93912910A patent/EP0647231B1/de not_active Expired - Lifetime
- 1993-06-08 NZ NZ253121A patent/NZ253121A/en unknown
- 1993-06-08 US US08/356,178 patent/US5475105A/en not_active Expired - Lifetime
- 1993-06-08 AU AU43238/93A patent/AU671130B2/en not_active Ceased
- 1993-06-11 IL IL10598993A patent/IL105989A/xx not_active IP Right Cessation
- 1993-06-18 ZA ZA934374A patent/ZA934374B/xx unknown
- 1993-06-19 CN CN93109449A patent/CN1042133C/zh not_active Expired - Fee Related
- 1993-12-11 CN CN93114691A patent/CN1039996C/zh not_active Expired - Fee Related
- 1993-12-14 TW TW082110584A patent/TW408126B/zh not_active IP Right Cessation
1994
- 1994-02-14 PH PH47479A patent/PH30466A/en unknown
- 1994-02-28 BG BG098600A patent/BG62350B2/bg unknown
- 1994-12-16 NO NO944892A patent/NO305176B1/no not_active IP Right Cessation
- 1994-12-19 FI FI945957A patent/FI108726B/fi active
1997
- 1997-10-20 GR GR970402736T patent/GR3025095T3/el unknown

Also Published As

Publication number	Publication date
EP0647231B1 (de)	1997-08-27
CZ288787B6 (cs)	2001-09-12
NO944892L (no)	1995-02-13
NO305176B1 (no)	1999-04-12
JP3171258B2 (ja)	2001-05-28
GR3025095T3 (en)	1998-01-30
DE59307217D1 (de)	1997-10-02
JPH07507771A (ja)	1995-08-31
ZA934374B (en)	1994-12-19
NZ253121A (en)	1995-12-21
CN1039996C (zh)	1998-09-30
BG62350B2 (bg)	1999-08-31
EP0647231A1 (de)	1995-04-12
CA2138289C (en)	2004-03-02
US5475105A (en)	1995-12-12
RU95105435A (ru)	1996-11-20
CN1105358A (zh)	1995-07-19
SG44782A1 (en)	1997-12-19
DE4243287A1 (de)	1993-12-23
CN1087341A (zh)	1994-06-01
CZ323794A3 (en)	1995-05-17
RU2135503C1 (ru)	1999-08-27
TW408126B (en)	2000-10-11
CN1042133C (zh)	1999-02-17
AU4323893A (en)	1994-01-24
HU218911B (hu)	2000-12-28
PH30466A (en)	1997-05-28
ES2107035T3 (es)	1997-11-16
ATE157366T1 (de)	1997-09-15
HUT71351A (en)	1995-11-28
NO944892D0 (no)	1994-12-16
FI108726B (fi)	2002-03-15
CA2138289A1 (en)	1994-01-06
IL105989A (en)	1997-02-18
FI945957A0 (fi)	1994-12-19
WO1994000458A1 (de)	1994-01-06
AU671130B2 (en)	1996-08-15
DK0647231T3 (da)	1997-09-29
IL105989A0 (en)	1993-10-20

Publication	Publication Date	Title
FI945957L (fi)	1994-12-19	N-substituoidut 3-atsabisyklo/3.2.0/heptaanijohdannaiset neurolepteinä jne.
FR2690919B1 (fr)	1995-05-05	Dérivés de l'indole.
FI954979A7 (fi)	1995-10-18	Kemoherkistävinä aineina käytettävät 10,11-metanodibentsosuberaanijohdannaiset
DE69330129D1 (en)	2001-05-17	Synthese von 1,4,7-thiazacyclononan-derivaten
GB9321855D0 (en)	1993-12-15	1,4-piperazine derivatives
FI962324L (fi)	1996-06-03	N-substituoituja atsabisykloalkaanijohdannaisia neuroleptisinä aineina ASF
FI932444L (fi)	1993-11-30	Ymppolymerkompositioner med modifierad slaghaollfasthet, vilka innehaoller polypropen med en bred molmassafoerdelning
ZA964646B (en)	1997-12-05	Substituted N-(indole-2-Carbonyl)-ß-alanimamides and derivatives as antidiabetic agents.
FI952424L (fi)	1995-11-20	11,21-bisfenyyli-19-norpregaanijohdannaisia
FI933151A7 (fi)	1994-01-14	5,10-metyleenitetrahydrofoolihappo-syklodekstriini-sulkeumayhdisteet
FI970448L (fi)	1997-04-03	N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina
FI962323L (fi)	1996-06-03	N-substituoidut atsabisykloheptaanijohdannaiset, kuten esim. neuroleptit
NO932842D0 (no)	1993-08-10	1,4-benzodioksanderivater
BR9408029A (pt)	1996-12-17	Derivados de 3-azabicicloalcanos N-substituídos
FI931459L (fi)	1993-10-02	Sammansaettningar med 1-klor-2,2,2-trifluoretyldifluor-metyleter
FI970449L (fi)	1997-04-03	N-substituoituja atsabisykloheptaanijohdannaisia, jotka ovat käyttökelpoisia neuroleptisinä aineina
DE59308564D1 (de)	1998-06-25	2,4-Dialkyl-6-sec-alkylphenole
FR2713641B1 (fr)	1997-04-11	Dérivés de l'épi-épibatidine.
FI941149L (fi)	1994-12-22	2,4-diamino-3-hydroksikarboksyylihapon johdannaisia
FI944655L (fi)	1994-10-05	Uudet 2,3-dihydro-2,2,4,6,7-penta-alkyyli-5-bentsofuranolit
DE59310221D1 (de)	2001-11-08	3-pyridyl-1,2,4-thiadiazole als pestizide
FI931794L (fi)	1993-10-23	Monokvaternaera 2,16-bispiperidinylandrostanderivat
HU9302748D0 (en)	1993-12-28	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[c,d]indole derivatives
KR950700297A (ko)	1995-01-16	5-HT3-수용체 길항제로서의 2,6-메타노-2H-퀴놀리진 유도체(2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist)
FI934297L (fi)	1994-04-02	Fosfolipidderivat, innehaollande grundaemnen ur den femte huvudgruppen med ett hoegt ordingstal