FI944602L - Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit - Google Patents
Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit Download PDFInfo
- Publication number
- FI944602L FI944602L FI944602A FI944602A FI944602L FI 944602 L FI944602 L FI 944602L FI 944602 A FI944602 A FI 944602A FI 944602 A FI944602 A FI 944602A FI 944602 L FI944602 L FI 944602L
- Authority
- FI
- Finland
- Prior art keywords
- pharmaceutically active
- heterocyclic amines
- active bicyclic
- bicyclic
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86364692A | 1992-04-03 | 1992-04-03 | |
| PCT/US1993/002188 WO1993020078A1 (en) | 1992-04-03 | 1993-03-16 | Pharmaceutically active bicyclic-heterocyclic amines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI944602A0 FI944602A0 (fi) | 1994-10-03 |
| FI944602A7 FI944602A7 (fi) | 1994-10-03 |
| FI944602L true FI944602L (fi) | 1994-10-03 |
Family
ID=25341481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI944602A FI944602L (fi) | 1992-04-03 | 1993-03-16 | Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0633886B1 (fi) |
| JP (1) | JPH08502721A (fi) |
| KR (1) | KR100284473B1 (fi) |
| AT (1) | ATE197051T1 (fi) |
| AU (1) | AU675932B2 (fi) |
| CA (1) | CA2130937A1 (fi) |
| CZ (1) | CZ236494A3 (fi) |
| DE (1) | DE69329574T2 (fi) |
| DK (1) | DK0633886T3 (fi) |
| ES (1) | ES2150941T3 (fi) |
| FI (1) | FI944602L (fi) |
| GR (1) | GR3035188T3 (fi) |
| HU (1) | HUT70954A (fi) |
| LV (1) | LV12794B (fi) |
| MX (1) | MX9301847A (fi) |
| NO (1) | NO303542B1 (fi) |
| PL (2) | PL175347B1 (fi) |
| PT (1) | PT633886E (fi) |
| RU (1) | RU2103272C1 (fi) |
| SK (1) | SK119194A3 (fi) |
| WO (1) | WO1993020078A1 (fi) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU694853B2 (en) * | 1995-03-02 | 1998-07-30 | Pharmacia & Upjohn Company | Pyrimido{4,5-b}indoles |
| US5753635A (en) * | 1996-08-16 | 1998-05-19 | Berlex Laboratories, Inc. | Purine derivatives and their use as anti-coagulants |
| KR20000057137A (ko) | 1996-11-19 | 2000-09-15 | 스티븐 엠. 오드레 | 아릴 및 헤테로아릴로 치환된 융합 피롤 항염증제 |
| WO1998024453A1 (en) * | 1996-12-05 | 1998-06-11 | Nippon Shinyaku Co., Ltd. | Remedies for myelopathy |
| NZ336659A (en) * | 1997-01-08 | 2001-01-26 | Upjohn Co | Pharmaceutically active pyrimido[4,5-b]indoles |
| GB9716657D0 (en) | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| GB2331988B (en) * | 1997-12-04 | 2003-04-16 | Imperial College | Polycyclic sulphamate inhibitors or oestrone sulphatase |
| GB9803226D0 (en) | 1998-02-17 | 1998-04-08 | Zeneca Ltd | Chemical compounds |
| TR200003513T2 (tr) | 1998-06-02 | 2001-06-21 | Osi Pharmaceuticals, Inc. | Pirolo[2,3d]Pirimidin kompozisyonları ve kullanımları |
| US6878716B1 (en) | 1998-06-02 | 2005-04-12 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptor and uses thereof |
| US6686366B1 (en) | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
| PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
| CA2342855A1 (en) * | 1998-09-04 | 2000-03-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel pyranoses |
| GB9902452D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902461D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902453D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902455D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9902459D0 (en) | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| GB9918035D0 (en) | 1999-07-30 | 1999-09-29 | Novartis Ag | Organic compounds |
| US6680322B2 (en) | 1999-12-02 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
| DE60030002T2 (de) | 1999-12-02 | 2007-03-08 | Osi Pharmaceuticals, Inc. | Für den adenosin-a1-a2a-und-a3-rezeptor spezifische verbindungen und verwendungen davon |
| US7160890B2 (en) | 1999-12-02 | 2007-01-09 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
| US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
| CO5271715A1 (es) | 1999-12-21 | 2003-04-30 | Sugen Inc | 7-aza-indolin-2-onas sustituidas en 4 y su uso como inhibidores de proteiuna quinasa |
| GB0000625D0 (en) | 2000-01-13 | 2000-03-01 | Zeneca Ltd | Chemical compounds |
| CA2399791A1 (en) | 2000-02-11 | 2001-08-16 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases |
| US20020061897A1 (en) | 2000-03-30 | 2002-05-23 | Elliott Richard L. | Neuropeptide Y antagonists |
| WO2002004447A1 (en) * | 2000-07-11 | 2002-01-17 | Pharma Mar, S.A. | Variolin derivatives as anti-cancer agents |
| JP2004513076A (ja) | 2000-07-25 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病治療で有用なn−置換インドール類 |
| SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
| US6673802B2 (en) | 2000-12-01 | 2004-01-06 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
| US6680324B2 (en) | 2000-12-01 | 2004-01-20 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptors and uses thereof |
| GB0100622D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds V111 |
| GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
| JP2005529062A (ja) | 2001-11-30 | 2005-09-29 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | アデノシンa1及びa3受容体に特異的な化合物とその使用 |
| CN101973998A (zh) | 2001-12-20 | 2011-02-16 | Osi药物公司 | 吡咯并嘧啶A2b选择性拮抗剂化合物 |
| CN1620294A (zh) | 2001-12-20 | 2005-05-25 | Osi药物公司 | 嘧啶a2b选择性拮抗剂化合物,它们的合成及用途 |
| EP1633756B1 (en) | 2003-04-09 | 2008-12-24 | Biogen Idec MA Inc. | A2a adenosine receptor antagonists |
| EP1615931A1 (en) | 2003-04-09 | 2006-01-18 | Biogen Idec MA Inc. | Triazolopyrazines and methods of making and using the same |
| US7285550B2 (en) | 2003-04-09 | 2007-10-23 | Biogen Idec Ma Inc. | Triazolotriazines and pyrazolotriazines and methods of making and using the same |
| GB0308208D0 (en) | 2003-04-09 | 2003-05-14 | Glaxo Group Ltd | Chemical compounds |
| US20070185217A1 (en) | 2003-12-23 | 2007-08-09 | Abraxis Bioscience, Inc. | Propofol analogs, process for their preparation, and methods of use |
| WO2005085265A1 (ja) * | 2004-03-04 | 2005-09-15 | Kissei Pharmaceutical Co., Ltd. | 縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途 |
| MXPA06014798A (es) | 2004-06-17 | 2007-06-22 | Wyeth Corp | Antagonistas del receptor de hormona para liberar gonadotropina. |
| RU2007101509A (ru) | 2004-06-17 | 2008-07-27 | Уайт (Us) | Способ получения антагонистов рецепторов гормона, высвобождающего гонадотропин |
| ATE405549T1 (de) | 2004-06-18 | 2008-09-15 | Biolipox Ab | Zur behandlung von entzündungen geeignete indole |
| FR2880626B1 (fr) * | 2005-01-13 | 2008-04-18 | Aventis Pharma Sa | Derives de la purine, compositions les contenant et utilisation |
| DE602005026867D1 (de) | 2005-01-19 | 2011-04-21 | Biolipox Ab | Entzündungshemmende indol-derivate |
| US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| FR2884824B1 (fr) | 2005-04-20 | 2007-07-13 | Sanofi Aventis Sa | Derives de 1h-pyrimido[4,5-b]indole, leur preparation et leur application en therapeutique |
| US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
| UA95788C2 (en) | 2005-12-15 | 2011-09-12 | Ф. Хоффманн-Ля Рош Аг | Fused pyrrole derivatives |
| KR100749216B1 (ko) * | 2006-08-30 | 2007-08-13 | 위아 주식회사 | 4륜구동차량용 부변속기 |
| CN101535253A (zh) | 2006-11-09 | 2009-09-16 | 弗·哈夫曼-拉罗切有限公司 | 吲哚和苯并呋喃2-甲酰胺衍生物 |
| RU2472797C2 (ru) * | 2007-08-08 | 2013-01-20 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | ПРОИЗВОДНЫЕ 2-[(2-(ФЕНИЛАМИНО)-1Н-ПИРРОЛО[2,3-d]ПИРИМИДИН-4-ИЛ)АМИНО]БЕНЗАМИДА В КАЧЕСТВЕ ИНГИБИТОРОВ IGF-1R ДЛЯ ЛЕЧЕНИЯ РАКА |
| RU2477282C2 (ru) * | 2007-08-17 | 2013-03-10 | Эл Джи Лайф Сайенсиз Лтд. | Соединения индола в качестве ингибиторов клеточного некроза |
| AR070127A1 (es) | 2008-01-11 | 2010-03-17 | Novartis Ag | Pirrolo - pirimidinas y pirrolo -piridinas |
| BRPI0906727A2 (pt) | 2008-01-31 | 2015-08-04 | Sanofi Aventis | Azaindol-3-carboxamidas cíclicas, sua preparação e seu uso como produtos farmacêuticos |
| TW200938201A (en) * | 2008-02-07 | 2009-09-16 | Chugai Pharmaceutical Co Ltd | Pyrrolopyrimidine derivative as PI3K inhibitor and use thereof |
| WO2010056320A2 (en) * | 2008-11-11 | 2010-05-20 | Tyrogenex, Inc. | Pi3k/mtor kinase inhibitors |
| US20130196990A1 (en) | 2010-10-06 | 2013-08-01 | Junya Qu | Benzimidazole Derivatives As PI3 Kinase Inhibitors |
| AU2012213080B2 (en) * | 2011-01-31 | 2014-03-27 | Novartis Ag | Novel heterocyclic derivatives |
| BR112013023266B8 (pt) | 2011-03-15 | 2021-04-06 | L Livermore Nat Security Llc | inibidores da girase tricíclicos |
| PH12014500912A1 (en) | 2011-10-28 | 2014-06-09 | Novartis Ag | Novel purine derivatives and their use in the treatment of disease |
| CN104144931B (zh) | 2012-01-27 | 2018-04-10 | 蒙特利尔大学 | 嘧啶并[4,5‑b]吲哚衍生物及其在造血干细胞的扩增中的应用 |
| PE20150153A1 (es) | 2012-06-29 | 2015-02-05 | Pfizer | 7H-PIRROLO[2,3-d]PIRIMIDINAS 4-(AMINO-SUBSTITUIDAS) NOVEDOSAS COMO INHIBIDORES DE LRRK2 |
| JP6487921B2 (ja) | 2013-12-17 | 2019-03-20 | ファイザー・インク | LRRK2阻害薬としての新規の3,4−二置換−1H−ピロロ[2,3−b]ピリジンおよび4,5−二置換−7H−ピロロ[2,3−c]ピリダジン |
| EP3116876A4 (en) | 2014-03-13 | 2017-10-25 | Agency For Science, Technology And Research | Fused pyrimidine-based hydroxamate derivatives |
| BR112017005713B1 (pt) * | 2014-09-22 | 2023-09-26 | National Health Research Institutes | Composto de fórmula (i) e composição farmacêutica |
| CN107922926B (zh) | 2015-06-05 | 2021-09-10 | 赫马魁北克公司 | 培养和/或使造血干细胞分化为祖细胞的方法及其用途 |
| KR102161364B1 (ko) | 2015-09-14 | 2020-09-29 | 화이자 인코포레이티드 | LRRK2 억제제로서 이미다조[4,5-c]퀴놀린 및 이미다조[4,5-c][1,5]나프티리딘 유도체 |
| US9630968B1 (en) | 2015-12-23 | 2017-04-25 | Arqule, Inc. | Tetrahydropyranyl amino-pyrrolopyrimidinone and methods of use thereof |
| JP2019530650A (ja) | 2016-08-24 | 2019-10-24 | アークル インコーポレイテッド | アミノ−ピロロピリミジノン化合物およびその使用方法 |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| WO2019158731A1 (en) * | 2018-02-16 | 2019-08-22 | Ucb Biopharma Sprl | Pharmaceutical 6,5 heterobicyclic ring derivatives |
| AU2019417833B2 (en) * | 2018-12-31 | 2024-11-07 | Biomea Fusion, Inc. | Irreversible inhibitors of menin-MLL interaction |
| EP4161519A4 (en) * | 2020-06-03 | 2024-07-17 | Yumanity Therapeutics, Inc. | PURINES AND METHODS OF USE |
| TW202216693A (zh) * | 2020-06-26 | 2022-05-01 | 美商坦帕斯醫療公司 | Trex1抑制劑及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB864145A (en) * | 1959-06-02 | 1961-03-29 | Thomae Gmbh Dr K | Novel purines and a process for their manufacture |
| GB1268772A (en) * | 1968-03-15 | 1972-03-29 | Glaxo Lab Ltd | NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME |
| KR970009225B1 (ko) * | 1989-09-19 | 1997-06-09 | 데이진 가부시끼가이샤 | 피롤로[2,3-디] 피리미딘 유도체, 그의 제조방법 및 그것을 유효성분으로 하는 의약제제 |
-
1993
- 1993-03-16 PL PL93305430A patent/PL175347B1/pl not_active IP Right Cessation
- 1993-03-16 HU HU9402829A patent/HUT70954A/hu unknown
- 1993-03-16 CA CA002130937A patent/CA2130937A1/en not_active Abandoned
- 1993-03-16 PL PL93317810A patent/PL175327B1/pl not_active IP Right Cessation
- 1993-03-16 RU RU94042466A patent/RU2103272C1/ru not_active IP Right Cessation
- 1993-03-16 JP JP5517457A patent/JPH08502721A/ja active Pending
- 1993-03-16 CZ CZ942364A patent/CZ236494A3/cs unknown
- 1993-03-16 WO PCT/US1993/002188 patent/WO1993020078A1/en not_active Ceased
- 1993-03-16 DE DE69329574T patent/DE69329574T2/de not_active Expired - Fee Related
- 1993-03-16 AT AT93908303T patent/ATE197051T1/de not_active IP Right Cessation
- 1993-03-16 PT PT93908303T patent/PT633886E/pt unknown
- 1993-03-16 AU AU39174/93A patent/AU675932B2/en not_active Ceased
- 1993-03-16 KR KR1019940703452A patent/KR100284473B1/ko not_active Expired - Fee Related
- 1993-03-16 EP EP93908303A patent/EP0633886B1/en not_active Expired - Lifetime
- 1993-03-16 DK DK93908303T patent/DK0633886T3/da active
- 1993-03-16 ES ES93908303T patent/ES2150941T3/es not_active Expired - Lifetime
- 1993-03-16 SK SK1191-94A patent/SK119194A3/sk unknown
- 1993-03-16 FI FI944602A patent/FI944602L/fi not_active Application Discontinuation
- 1993-03-31 MX MX9301847A patent/MX9301847A/es not_active IP Right Cessation
-
1994
- 1994-09-30 NO NO943655A patent/NO303542B1/no unknown
-
2001
- 2001-01-04 GR GR20010400006T patent/GR3035188T3/el not_active IP Right Cessation
- 2001-10-18 LV LVP-01-150A patent/LV12794B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0633886T3 (da) | 2000-12-18 |
| FI944602A0 (fi) | 1994-10-03 |
| AU675932B2 (en) | 1997-02-27 |
| NO943655D0 (no) | 1994-09-30 |
| FI944602A7 (fi) | 1994-10-03 |
| HU9402829D0 (en) | 1995-02-28 |
| MX9301847A (es) | 1993-10-01 |
| PT633886E (pt) | 2001-03-30 |
| NO303542B1 (no) | 1998-07-27 |
| WO1993020078A1 (en) | 1993-10-14 |
| LV12794B (lv) | 2002-06-20 |
| PL175327B1 (pl) | 1998-12-31 |
| SK119194A3 (en) | 1995-05-10 |
| CA2130937A1 (en) | 1993-10-14 |
| EP0633886A1 (en) | 1995-01-18 |
| CZ236494A3 (en) | 1994-12-15 |
| ATE197051T1 (de) | 2000-11-15 |
| KR100284473B1 (ko) | 2001-04-02 |
| RU94042466A (ru) | 1996-07-20 |
| DE69329574T2 (de) | 2001-05-31 |
| LV12794A (en) | 2002-02-20 |
| NO943655L (no) | 1994-12-05 |
| KR950700912A (ko) | 1995-02-20 |
| RU2103272C1 (ru) | 1998-01-27 |
| GR3035188T3 (en) | 2001-04-30 |
| HUT70954A (en) | 1995-11-28 |
| JPH08502721A (ja) | 1996-03-26 |
| EP0633886B1 (en) | 2000-10-18 |
| DE69329574D1 (de) | 2000-11-23 |
| PL175347B1 (pl) | 1998-12-31 |
| AU3917493A (en) | 1993-11-08 |
| ES2150941T3 (es) | 2000-12-16 |
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