FI881158L - Menetelmä terapeuttisesti käyttökelpoisen immunoglobuliinikonjugaatin valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisen immunoglobuliinikonjugaatin valmistamiseksi Download PDF

Info

Publication number: FI881158L
Authority: FI; Finland
Prior art keywords: preparing; therapeutically useful; immunoglobulin conjugate; useful immunoglobulin; conjugate
Prior art date: 1987-03-11

Application number

FI881158A

Other languages

English (en)

Swedish (sv)

Other versions

FI881158A0 (fi

FI98706B (fi

FI98706C (fi

Inventor

Ian Farquhar Mckenzie

Geoffrey Allan Pietersz

Mark John Smyth

Original Assignee

Erba Carlo Spa

Univ Melbourne

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-11

Filing date

1988-03-11

Publication date

1988-09-12

1988-03-11 Application filed by Erba Carlo Spa, Univ Melbourne filed Critical Erba Carlo Spa

1988-03-11 Publication of FI881158A0 publication Critical patent/FI881158A0/fi

1988-09-12 Publication of FI881158L publication Critical patent/FI881158L/fi

1997-04-30 Publication of FI98706B publication Critical patent/FI98706B/fi

1997-08-11 Application granted granted Critical

1997-08-11 Publication of FI98706C publication Critical patent/FI98706C/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
- A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Mycology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI881158A 1987-03-11 1988-03-11 Menetelmä terapeuttisesti käyttökelpoisen immunoglobuliinikonjugaatin valmistamiseksi FI98706C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
AUPI080387		1987-03-11
AUPI080387		1987-03-11
AUPI295587		1987-07-07
AUPI295587		1987-07-07

Publications (4)

Publication Number	Publication Date
FI881158A0 FI881158A0 (fi)	1988-03-11
FI881158L true FI881158L (fi)	1988-09-12
FI98706B FI98706B (fi)	1997-04-30
FI98706C FI98706C (fi)	1997-08-11

Family

ID=25643244

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI881158A FI98706C (fi)	1987-03-11	1988-03-11	Menetelmä terapeuttisesti käyttökelpoisen immunoglobuliinikonjugaatin valmistamiseksi

Country Status (29)

Country	Link
US (1)	US5798097A (fi)
JP (1)	JP2736255B2 (fi)
KR (1)	KR0130906B1 (fi)
CN (1)	CN1045621C (fi)
AT (1)	AT395375B (fi)
AU (1)	AU622105B2 (fi)
BE (1)	BE1001051A4 (fi)
CA (1)	CA1329156C (fi)
CH (1)	CH678815A5 (fi)
CZ (1)	CZ161288A3 (fi)
DE (1)	DE3808166C2 (fi)
DK (1)	DK173792B1 (fi)
ES (1)	ES2006109A6 (fi)
FI (1)	FI98706C (fi)
FR (1)	FR2612074B1 (fi)
GB (1)	GB2203154B (fi)
GR (1)	GR1000059B (fi)
HU (1)	HU205266B (fi)
IE (1)	IE64781B1 (fi)
IL (1)	IL85688A0 (fi)
IT (1)	IT8819746A0 (fi)
MY (1)	MY103231A (fi)
NL (1)	NL8800610A (fi)
NO (1)	NO178954C (fi)
NZ (1)	NZ223834A (fi)
PT (1)	PT86960B (fi)
RU (1)	RU2106147C1 (fi)
SE (1)	SE503402C2 (fi)
YU (1)	YU46858B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6824777B1 (en) *	1992-10-09	2004-11-30	Licentia Ltd.	Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
ES2357406T3 (es) *	1998-10-09	2011-04-26	Vegenics Limited	Flt4 (VEGFR-3) COMO DIANA PARA LA OBTENCIÓN DE IMÁGENES DE TUMORES Y TERAPIA ANTITUMORAL.
WO2002049672A2 (en) *	2000-12-21	2002-06-27	Mcgill University	Conjugates of antibodies and anticancer drugs
CA2435503C (en) *	2001-01-19	2011-02-22	Ludwig Institute For Cancer Research	Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
WO2004094647A2 (en) *	2003-04-18	2004-11-04	Cytovia, Inc.	Methods of treating diseases responsive to induction of apoptosis and screening assays
GB0511266D0 (en) *	2005-06-02	2005-07-13	Trust	Chemical compounds
US20080108138A1 (en) *	2006-06-13	2008-05-08	Vermette Patrick	Bioactive compositions and their use in cell patterning
EA034333B1 (ru)	2010-11-30	2020-01-29	Дженентек, Инк.	Варианты антитела для переноса соединения через гематоэнцефалический барьер
SI2956476T1 (sl)	2013-02-18	2020-03-31	Vegenics Pty Limited	Molekule za vezavo na ligande in uporabe le-teh
EP4157241A4 (en) *	2020-05-29	2025-01-08	The Regents of the University of California	AGENTS AND METHODS FOR THE TREATMENT OF TAUOPATHIES

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT346838B (de) *	1975-01-22	1978-11-27	Farmaceutici Italia	Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
AT343811B (de) *	1975-01-22	1978-06-26	Farmaceutici Italia	Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
GB1500421A (en) *	1975-01-22	1978-02-08	Farmaceutici Italia	Optically active anthracyclinones
AT343812B (de) *	1975-01-22	1978-06-26	Farmaceutici Italia	Verfahren zur herstellung von neuen optisch aktiven daunosaminylderivaten von anthracyclinonen
GB1511680A (en)	1975-11-18	1978-05-24	Farmaceutici Italia	Daunosaminyl anthracyclinones
GB1541436A (en) *	1976-02-02	1979-02-28	Searle & Co	Immunological materials
US5162512A (en) *	1982-03-09	1992-11-10	Cytogen Corporation	Amine derivatives of anthracycline antibodies
US4867973A (en) *	1984-08-31	1989-09-19	Cytogen Corporation	Antibody-therapeutic agent conjugates
US4950738A (en) *	1984-09-13	1990-08-21	Cytogen Corporation	Amine derivatives of anthracycline antibiotics
JPS59186924A (ja) *	1983-04-08	1984-10-23	Kureha Chem Ind Co Ltd	ヒト免疫グロブリン結合抗腫瘍剤
US4545985A (en)	1984-01-26	1985-10-08	The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services	Pseudomonas exotoxin conjugate immunotoxins
GB8413464D0 (en) *	1984-05-25	1984-07-04	Erba Farmitalia	Anthracycline-anionic polymer conjugates
JPS61155334A (ja) *	1984-12-28	1986-07-15	Teijin Ltd	殺細胞性修飾免疫グロブリン及びその製造方法
FR2584293B1 (fr) *	1985-07-04	1989-03-17	Ire Celltarg Sa	Anticorps utiles comme agents de pilotage et conjugues les incorporant

1988
- 1988-03-10 KR KR1019880002464A patent/KR0130906B1/ko not_active Expired - Fee Related
- 1988-03-10 AU AU12881/88A patent/AU622105B2/en not_active Expired
- 1988-03-10 IL IL85688A patent/IL85688A0/xx not_active IP Right Cessation
- 1988-03-10 IE IE70188A patent/IE64781B1/xx not_active IP Right Cessation
- 1988-03-10 CA CA000561042A patent/CA1329156C/en not_active Expired - Lifetime
- 1988-03-10 YU YU48288A patent/YU46858B/sh unknown
- 1988-03-10 JP JP63055074A patent/JP2736255B2/ja not_active Expired - Lifetime
- 1988-03-10 MY MYPI88000250A patent/MY103231A/en unknown
- 1988-03-10 ES ES8800719A patent/ES2006109A6/es not_active Expired
- 1988-03-10 BE BE8800268A patent/BE1001051A4/fr not_active IP Right Cessation
- 1988-03-10 NZ NZ223834A patent/NZ223834A/xx unknown
- 1988-03-10 HU HU881160A patent/HU205266B/hu unknown
- 1988-03-11 SE SE8800886A patent/SE503402C2/sv not_active IP Right Cessation
- 1988-03-11 GB GB8805865A patent/GB2203154B/en not_active Expired - Lifetime
- 1988-03-11 NL NL8800610A patent/NL8800610A/nl not_active IP Right Cessation
- 1988-03-11 CH CH936/88A patent/CH678815A5/de not_active IP Right Cessation
- 1988-03-11 FI FI881158A patent/FI98706C/fi not_active IP Right Cessation
- 1988-03-11 NO NO881105A patent/NO178954C/no not_active IP Right Cessation
- 1988-03-11 DK DK198801315A patent/DK173792B1/da not_active IP Right Cessation
- 1988-03-11 CN CN88101810A patent/CN1045621C/zh not_active Expired - Lifetime
- 1988-03-11 GR GR880100148A patent/GR1000059B/el not_active IP Right Cessation
- 1988-03-11 CZ CS881612A patent/CZ161288A3/cs not_active IP Right Cessation
- 1988-03-11 DE DE3808166A patent/DE3808166C2/de not_active Expired - Lifetime
- 1988-03-11 IT IT8819746A patent/IT8819746A0/it unknown
- 1988-03-11 AT AT0067488A patent/AT395375B/de not_active IP Right Cessation
- 1988-03-11 FR FR888803233A patent/FR2612074B1/fr not_active Expired - Lifetime
- 1988-03-11 PT PT86960A patent/PT86960B/pt not_active IP Right Cessation
1992
- 1992-06-15 RU SU5052164A patent/RU2106147C1/ru active
1995
- 1995-04-11 US US08/420,712 patent/US5798097A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FR2612074A1 (fr)	1988-09-16
SE503402C2 (sv)	1996-06-10
CH678815A5 (fi)	1991-11-15
IE880701L (en)	1988-09-11
HUT46547A (en)	1988-11-28
HU205266B (en)	1992-04-28
IE64781B1 (en)	1995-09-06
FI881158A0 (fi)	1988-03-11
JPS63301832A (ja)	1988-12-08
RU2106147C1 (ru)	1998-03-10
YU46858B (sh)	1994-06-24
DE3808166A1 (de)	1988-09-22
AT395375B (de)	1992-12-10
IL85688A0 (en)	1988-08-31
NO881105D0 (no)	1988-03-11
US5798097A (en)	1998-08-25
AU1288188A (en)	1988-09-15
FR2612074B1 (fr)	1991-06-21
FI98706B (fi)	1997-04-30
IT8819746A0 (it)	1988-03-11
NO178954C (no)	1996-07-10
KR0130906B1 (ko)	1998-04-23
CA1329156C (en)	1994-05-03
MY103231A (en)	1993-05-29
SE8800886D0 (sv)	1988-03-11
NZ223834A (en)	1990-05-28
NL8800610A (nl)	1988-10-03
DK173792B1 (da)	2001-11-05
NO881105L (no)	1988-09-12
CZ281193B6 (cs)	1996-07-17
GR1000059B (el)	1990-06-27
GB2203154B (en)	1991-06-26
AU622105B2 (en)	1992-04-02
SE8800886L (sv)	1989-09-12
DK131588A (da)	1988-09-12
NO178954B (no)	1996-04-01
ATA67488A (de)	1992-05-15
CN1045621C (zh)	1999-10-13
PT86960A (pt)	1988-04-01
PT86960B (pt)	1992-06-30
JP2736255B2 (ja)	1998-04-02
BE1001051A4 (fr)	1989-06-20
CZ161288A3 (en)	1996-07-17
DK131588D0 (da)	1988-03-11
ES2006109A6 (es)	1989-04-01
KR880010775A (ko)	1988-10-24
GR880100148A (en)	1989-01-31
DE3808166C2 (de)	1997-08-28
FI98706C (fi)	1997-08-11
CN88101810A (zh)	1988-11-09
GB2203154A (en)	1988-10-12
NL195078C (fi)	2003-07-30
YU48288A (en)	1989-08-31
GB8805865D0 (en)	1988-04-13

Publication	Publication Date	Title
FI883426L (fi)	1989-01-21	Menetelmä terapeuttisesti käyttökelpoisen pentasakkaridin valmistamiseksi
FI885409A7 (fi)	1989-05-24	Menetelmä uusien terapeuttisesti käyttökelpoisten pyridatsiiniamiinijohdannaisten valmistamiseksi
FI862631A7 (fi)	1986-12-25	Menetelmä terapeuttisesti käyttökelpoisen membraaniankkuri-vaikuttava-ainekonjugaatin valmistamiseksi
FI893929L (fi)	1989-08-22	Menetelmä stabiilin sinkki-protamiini- -interferonikompleksin valmistamiseksi
FI981807L (fi)	1998-08-24	Menetelmä terapeuttisesti käyttökelpoisten starburst-konjugaattien valmistamiseksi
FI854797A7 (fi)	1986-06-22	Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi
FI883388L (fi)	1989-01-18	Menetelmä uusien terapeuttisesti käyttökelpoisten peptidien valmistamiseksi
FI890282L (fi)	1989-07-21	Menetelmä terapeuttisesti käyttökelpoisten 23,24-didehydro-25-hydroksikalsiferolijohdannaisten valmistamiseksi
FI884627A7 (fi)	1989-04-10	Menetelmä uusien terapeuttisesti käyttökelpoisten dideoksisytidiinijohdannaisten valmistamiseksi
FI880467A7 (fi)	1988-08-05	Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 3,4-dihydro-2H-bentsopyraanien valmistamiseksi
FI883672A7 (fi)	1989-02-08	Menetelmä terapeuttisesti käyttökelpoisten aminoalkoksifenyylijohdannaisten valmistamiseksi
FI890127L (fi)	1989-07-14	Menetelmä terapeuttisesti käyttökelpoisen hirudiinijohdannaisen valmistamiseksi
FI881525A7 (fi)	1988-10-02	Menetelmä uusien terapeuttisesti käyttökelpoisten N-aryylipiperatsiiniasetamidijohdannaisten valmistamiseksi
FI911207L (fi)	1991-09-28	Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi
FI881158L (fi)	1988-09-12	Menetelmä terapeuttisesti käyttökelpoisen immunoglobuliinikonjugaatin valmistamiseksi
FI890257A7 (fi)	1989-07-21	Menetelmä terapeuttisesti käyttökelpoisten pyridiinijohdannaisten valmistamiseksi
FI885560A7 (fi)	1988-11-30	Menetelmä uusien terapeuttisesti käyttökelpoisten bisfenyylialkyylipiperatsiinijohdannaisten valmistamiseksi
FI893003L (fi)	1989-12-21	Menetelmä uusien terapeuttisesti käyttökelpoisten neplanosiinijohdannaisten valmistamiseksi
FI880468A7 (fi)	1988-08-05	Menetelmä terapeuttisesti käyttökelpoisten N-bentsopyranyylilaktaamien valmistamiseksi
FI891144L (fi)	1989-09-10	Menetelmä uusien terapeuttisesti käyttökelpoisten suolayhdisteiden valmistamiseksi
FI911420L (fi)	1991-09-27	Menetelmä terapeuttisesti käyttökelpoisten yhdisteiden valmistamiseksi
FI886066A7 (fi)	1989-07-01	Menetelmä uusien terapeuttisesti käyttökelpoisten substituoitujen styreenijohdannaisten valmistamiseksi
FI884473A7 (fi)	1989-04-02	Menetelmä terapeuttisesti käyttökelpoisten fenoksialkyylipyrokatekolijohdannaisten valmistamiseksi
FI901775A7 (fi)	1990-10-07	Menetelmä uusien terapeuttisesti käyttökelpoisten tiourasiilijohdannaisten valmistamiseksi
FI891062L (fi)	1989-09-11	Menetelmä terapeuttisesti käyttökelpoisen sialosyyliglyseridin valmistamiseksi

Legal Events

Date	Code	Title	Description
1988-03-11	FG	Patent granted	Owner name: PHARMACIA & UPJOHN S.P.A.
1996-11-29	GB	Transfer or assigment of application	Owner name: PHARMACIA & UPJOHN S.P.A.
1997-04-01	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: PHARMACIA ITALIA S.P.A. Owner name: THE UNIVERSITY OF MELBOURNE
2008-04-22	MA	Patent expired