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FI911207L - Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi - Google Patents

Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi Download PDF

Info

Publication number
FI911207L
FI911207L FI911207A FI911207A FI911207L FI 911207 L FI911207 L FI 911207L FI 911207 A FI911207 A FI 911207A FI 911207 A FI911207 A FI 911207A FI 911207 L FI911207 L FI 911207L
Authority
FI
Finland
Prior art keywords
preparing
therapeutically useful
novel therapeutically
useful retinoid
retinoid
Prior art date
Application number
FI911207A
Other languages
English (en)
Swedish (sv)
Other versions
FI96201B (fi
FI911207A0 (fi
FI96201C (fi
Inventor
Guenter Gross
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI911207A0 publication Critical patent/FI911207A0/fi
Publication of FI911207L publication Critical patent/FI911207L/fi
Publication of FI96201B publication Critical patent/FI96201B/fi
Application granted granted Critical
Publication of FI96201C publication Critical patent/FI96201C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Vapour Deposition (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
FI911207A 1990-03-27 1991-03-12 Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi FI96201C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27
CH100890 1990-03-27

Publications (4)

Publication Number Publication Date
FI911207A0 FI911207A0 (fi) 1991-03-12
FI911207L true FI911207L (fi) 1991-09-28
FI96201B FI96201B (fi) 1996-02-15
FI96201C FI96201C (fi) 1996-05-27

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911207A FI96201C (fi) 1990-03-27 1991-03-12 Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi

Country Status (23)

Country Link
US (1) US5158773A (fi)
EP (1) EP0449099B1 (fi)
JP (1) JPH0798797B2 (fi)
KR (1) KR960008666B1 (fi)
AT (1) ATE130848T1 (fi)
AU (1) AU646439B2 (fi)
CA (1) CA2037150C (fi)
DE (1) DE59106962D1 (fi)
DK (1) DK0449099T3 (fi)
ES (1) ES2080848T3 (fi)
FI (1) FI96201C (fi)
GR (1) GR3019014T3 (fi)
HR (1) HRP930344B1 (fi)
HU (1) HU207980B (fi)
IE (1) IE71178B1 (fi)
IL (1) IL97607A (fi)
MC (1) MC2222A1 (fi)
NO (1) NO174801B (fi)
NZ (1) NZ237513A (fi)
PT (1) PT97148B (fi)
SA (1) SA91110302B1 (fi)
YU (1) YU48480B (fi)
ZA (1) ZA912075B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
CA2258593A1 (en) * 1996-07-02 1998-01-08 Abraham Nudelman Retinoyloxy(substituted)alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6043389A (en) 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US6124495A (en) 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
CN108348456B (zh) 2015-10-30 2021-09-17 亭铂医药有限责任公司 异维甲酸制剂及其用途和方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider

Also Published As

Publication number Publication date
FI96201B (fi) 1996-02-15
YU48480B (sh) 1998-09-18
IL97607A (en) 1996-08-04
ZA912075B (en) 1991-12-24
NO174801C (fi) 1994-07-13
FI911207A0 (fi) 1991-03-12
US5158773A (en) 1992-10-27
IE911005A1 (en) 1991-10-09
NO911233D0 (no) 1991-03-26
MC2222A1 (fr) 1993-02-02
IE71178B1 (en) 1997-01-29
EP0449099A3 (en) 1993-02-03
NO911233L (no) 1991-09-30
FI96201C (fi) 1996-05-27
SA91110302B1 (ar) 2001-10-07
PT97148B (pt) 1998-07-31
JPH04221362A (ja) 1992-08-11
YU45591A (sh) 1994-04-05
ES2080848T3 (es) 1996-02-16
ATE130848T1 (de) 1995-12-15
EP0449099B1 (de) 1995-11-29
CA2037150C (en) 1999-12-28
HRP930344A2 (en) 1994-10-31
EP0449099A2 (de) 1991-10-02
AU646439B2 (en) 1994-02-24
PT97148A (pt) 1991-11-29
AU7383191A (en) 1991-10-03
CA2037150A1 (en) 1991-09-28
DK0449099T3 (da) 1996-01-22
IL97607A0 (en) 1992-06-21
NO174801B (no) 1994-04-05
HUT57178A (en) 1991-11-28
NZ237513A (en) 1993-09-27
KR960008666B1 (en) 1996-06-28
KR910016674A (ko) 1991-11-05
HU207980B (en) 1993-07-28
DE59106962D1 (de) 1996-01-11
JPH0798797B2 (ja) 1995-10-25
GR3019014T3 (en) 1996-05-31
HRP930344B1 (en) 1998-12-31
HU910968D0 (en) 1991-10-28

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MA Patent expired