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FI880868A0 - Som mellanprodukter användbara tetrazolföreningar - Google Patents

Som mellanprodukter användbara tetrazolföreningar

Info

Publication number
FI880868A0
FI880868A0 FI880868A FI880868A FI880868A0 FI 880868 A0 FI880868 A0 FI 880868A0 FI 880868 A FI880868 A FI 880868A FI 880868 A FI880868 A FI 880868A FI 880868 A0 FI880868 A0 FI 880868A0
Authority
FI
Finland
Prior art keywords
intermediates
compounds useful
tetrazole compounds
tetrazole
useful
Prior art date
Application number
FI880868A
Other languages
English (en)
Finnish (fi)
Other versions
FI96600B (sv
FI880868A7 (sv
FI96600C (sv
Inventor
John J Wright
Sing-Yuen Sit
Neelakantan Balasubramanian
Peter J Brown
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI880868A0 publication Critical patent/FI880868A0/sv
Publication of FI880868A7 publication Critical patent/FI880868A7/sv
Priority to FI931580A priority Critical patent/FI96602C/sv
Priority to FI931579A priority patent/FI96953C/sv
Publication of FI96600B publication Critical patent/FI96600B/sv
Application granted granted Critical
Publication of FI96600C publication Critical patent/FI96600C/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI880868A 1987-02-25 1988-02-24 Som mellanprodukter användbara tetrazolföreningar FI96600C (sv)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI931580A FI96602C (sv) 1987-02-25 1993-04-07 Förfarande för framställning av terapeutiskt aktiva tetrazolderivat
FI931579A FI96953C (sv) 1987-02-25 1993-04-07 Tetrazolderivat och förfarande för deras framställning

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1855887A 1987-02-25 1987-02-25
US1855887 1987-02-25
US15151288 1988-02-18
US07/151,512 US4898949A (en) 1987-02-25 1988-02-18 Intermediates for the preparation of antihypercholesterolemic tetrazole compounds

Publications (4)

Publication Number Publication Date
FI880868A0 true FI880868A0 (sv) 1988-02-24
FI880868A7 FI880868A7 (sv) 1988-08-26
FI96600B FI96600B (sv) 1996-04-15
FI96600C FI96600C (sv) 1996-07-25

Family

ID=26691250

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880868A FI96600C (sv) 1987-02-25 1988-02-24 Som mellanprodukter användbara tetrazolföreningar

Country Status (27)

Country Link
US (1) US4898949A (sv)
JP (1) JP2603284B2 (sv)
KR (1) KR960007167B1 (sv)
CN (1) CN1030077C (sv)
AT (1) AT395588B (sv)
AU (1) AU610562B2 (sv)
BE (1) BE1002115A3 (sv)
CA (1) CA1328269C (sv)
CH (1) CH678182A5 (sv)
DE (1) DE3805789C2 (sv)
DK (2) DK97388A (sv)
ES (1) ES2009547A6 (sv)
FI (1) FI96600C (sv)
FR (1) FR2611201B1 (sv)
GB (1) GB2202845B (sv)
GR (1) GR1000473B (sv)
HU (3) HU201534B (sv)
IE (1) IE61608B1 (sv)
IT (1) IT1216752B (sv)
LU (1) LU87143A1 (sv)
MY (1) MY102290A (sv)
NL (1) NL8800468A (sv)
NO (1) NO178432C (sv)
NZ (1) NZ223621A (sv)
PT (1) PT86821B (sv)
SE (3) SE504553C2 (sv)
YU (1) YU46781B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
FI94339C (sv) 1989-07-21 1995-08-25 Warner Lambert Co Förfarande för framställning av farmaceutiskt användbar /R-(R*,R*)/-2-(4-fluorfenyl)- , -dihydroxi-5-(1-metyletyl)-3-fenyl-4-/(fenylamino)karbonyl/-1H-pyrrol-1-heptansyra och farmaceutiskt användbara salter därav
US5260325A (en) * 1991-08-19 1993-11-09 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking tertiary amides
CA2137049A1 (en) * 1993-12-15 1995-06-16 John K. Thottathil Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds
US6433213B1 (en) * 1997-12-19 2002-08-13 Warner-Lambert Company Process for the synthesis of 1,3-diols

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160100A (en) * 1973-03-23 1979-07-03 American Home Products Corporation Oxamic acid derivatives
US4013647A (en) * 1976-03-23 1977-03-22 American Home Products Corporation Morpholine containing tetrazole-5-carboxamide derivatives
JPS53147073A (en) * 1977-05-24 1978-12-21 Sankyo Co Ltd Mevalonolactone derivatives
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4375475A (en) * 1979-08-17 1983-03-01 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
NZ194557A (en) * 1979-08-17 1984-09-28 Merck & Co Inc Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions
EP0068038B1 (en) * 1981-06-29 1985-09-25 Merck & Co. Inc. (+)-(4r,6s)-(e)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2h-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same
WO1984002131A1 (fr) * 1982-11-22 1984-06-07 Sandoz Ag Produits analogues de mevalolactone et leurs derives, leurs procedes de production, compositions pharmaceutiques les contenant ainsi que leur utilisation en tant que produits pharmaceutiques
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
IE840153L (en) * 1983-01-24 1984-07-24 Sandoz Ltd Mevalonolactone analogues and related hydroxy acids for¹control of blood cholesterol levels.
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
CA1327360C (en) * 1983-11-14 1994-03-01 William F. Hoffman Oxo-analogs of mevinolin-like antihypercholesterolemic agents
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
ATE62906T1 (de) * 1984-06-22 1991-05-15 Sandoz Ag Pyrazolanaloge von mevalonolakton und abkoemmlinge davon, verfahren zu deren herstellung und deren verwendung.
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
US4621099A (en) * 1985-09-23 1986-11-04 Usv Pharmaceutical Corporation Polyene compounds useful in the treatment of allergic responses
US4681893A (en) * 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US4678806A (en) * 1986-09-02 1987-07-07 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds
AU601264B2 (en) * 1987-02-25 1990-09-06 Bristol-Myers Squibb Company Antihypercholesterolemic tetrazole compounds

Also Published As

Publication number Publication date
IE880502L (en) 1988-08-18
IT1216752B (it) 1990-03-08
FR2611201B1 (fr) 1991-01-11
IT8819526A0 (it) 1988-02-24
PT86821B (pt) 1992-05-29
CH678182A5 (sv) 1991-08-15
AU1213288A (en) 1988-09-01
SE9300977L (sv)
HU201534B (en) 1990-11-28
SE512485C2 (sv) 2000-03-20
ES2009547A6 (es) 1989-10-01
HUT47258A (en) 1989-02-28
NO178432B (no) 1995-12-18
LU87143A1 (fr) 1988-09-20
FI96600B (sv) 1996-04-15
DE3805789C2 (de) 2001-05-31
GB8804281D0 (en) 1988-03-23
YU36488A (en) 1990-02-28
AU610562B2 (en) 1991-05-23
HU895124D0 (sv) 1990-01-28
SE8800637D0 (sv) 1988-02-24
SE9300976D0 (sv) 1993-03-24
KR880009946A (ko) 1988-10-06
SE9300976L (sv) 1993-03-24
ATA46088A (de) 1992-06-15
NO880802L (no) 1988-08-26
YU46781B (sh) 1994-05-10
BE1002115A3 (fr) 1990-07-10
GB2202845B (en) 1991-05-22
HU201533B (en) 1990-11-28
GR1000473B (el) 1992-07-30
FI880868A7 (sv) 1988-08-26
NO880802D0 (no) 1988-02-24
SE504553C2 (sv) 1997-03-03
US4898949A (en) 1990-02-06
GB2202845A (en) 1988-10-05
SE9300977D0 (sv) 1993-03-24
NO178432C (no) 1996-03-27
MY102290A (en) 1992-05-15
DK97388A (da) 1988-08-26
SE503201C2 (sv) 1996-04-15
AT395588B (de) 1993-01-25
HU201532B (en) 1990-11-28
NL8800468A (nl) 1988-09-16
DK113897A (da) 1997-10-06
JPS63290872A (ja) 1988-11-28
CA1328269C (en) 1994-04-05
PT86821A (pt) 1988-03-01
JP2603284B2 (ja) 1997-04-23
SE8800637L (sv) 1988-08-26
DE3805789A1 (de) 1988-09-15
FI96600C (sv) 1996-07-25
CN1070642A (zh) 1993-04-07
FR2611201A1 (fr) 1988-08-26
KR960007167B1 (ko) 1996-05-29
DK97388D0 (da) 1988-02-24
IE61608B1 (en) 1994-11-16
NZ223621A (en) 1991-06-25
GR880100100A (en) 1988-12-16
CN1030077C (zh) 1995-10-18

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: BRISTOL-MYERS SQUIBB COMPANY

MA Patent expired